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Showing 1 to 12 of 593 entries
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Clinical trials of health education for hypertensive outpatients: design and baseline data.

Preventive medicine

Green LW, Levine DM, Deeds S.
PMID: 813195
Prev Med. 1975 Dec;4(4):417-25. doi: 10.1016/0091-7435(75)90030-4.

No abstract available.

Low-dose photon irradiation induces invasiveness through the SDF-1α/CXCR4 pathway in malignant mesothelioma cells.

Oncotarget

Yamauchi Y, Safi S, Orschiedt L, Gardyan A, Brons S, Rieber J, Nicolay NH, Huber PE, Eichhorn M, Dienemann H, Herth FJF, Weber KJ, Debus J, Hoffmann H, Rieken S.
PMID: 28978091
Oncotarget. 2017 Jul 10;8(40):68001-68011. doi: 10.18632/oncotarget.19134. eCollection 2017 Sep 15.

BACKGROUND: Low-dose photon irradiation has repeatedly been suspected to increase a risk of promoting local recurrence of disease or even systemic dissemination. The purpose of this study was to investigate the motility of malignant pleural mesothelioma (MPM) cell lines...

Demonstration of a beam loaded nanocoulomb-class laser wakefield accelerator.

Nature communications

Couperus JP, Pausch R, Köhler A, Zarini O, Krämer JM, Garten M, Huebl A, Gebhardt R, Helbig U, Bock S, Zeil K, Debus A, Bussmann M, Schramm U, Irman A.
PMID: 28887456
Nat Commun. 2017 Sep 08;8(1):487. doi: 10.1038/s41467-017-00592-7.

Laser-plasma wakefield accelerators have seen tremendous progress, now capable of producing quasi-monoenergetic electron beams in the GeV energy range with few-femtoseconds bunch duration. Scaling these accelerators to the nanocoulomb range would yield hundreds of kiloamperes peak current and stimulate...

Correlation of Particle Traversals with Clonogenic Survival Using Cell-Fluorescent Ion Track Hybrid Detector.

Frontiers in oncology

Dokic I, Niklas M, Zimmermann F, Mairani A, Seidel P, Krunic D, Jäkel O, Debus J, Greilich S, Abdollahi A.
PMID: 26697410
Front Oncol. 2015 Dec 07;5:275. doi: 10.3389/fonc.2015.00275. eCollection 2015.

Development of novel approaches linking the physical characteristics of particles with biological responses are of high relevance for the field of particle therapy. In radiobiology, the clonogenic survival of cells is considered the gold standard assay for the assessment...

Application of classical simulations for the computation of vibrational properties of free molecules.

Physical chemistry chemical physics : PCCP

Tikhonov DS, Sharapa DI, Schwabedissen J, Rybkin VV.
PMID: 27722605
Phys Chem Chem Phys. 2016 Oct 12;18(40):28325-28338. doi: 10.1039/c6cp05849c.

In this study, we investigate the ability of classical molecular dynamics (MD) and Monte-Carlo (MC) simulations for modeling the intramolecular vibrational motion. These simulations were used to compute thermally-averaged geometrical structures and infrared vibrational intensities for a benchmark set...

Kinetics and mechanism of the reaction of hydrogen sulfide with diaquacobinamide in aqueous solution.

European journal of inorganic chemistry

Salnikov DS, Makarov SV, van Eldik R, Kucherenko PN, Boss GR.
PMID: 25580081
Eur J Inorg Chem. 2014 Sep;2014(25):4123-4133. doi: 10.1002/ejic.201402082.

We conducted a detailed kinetic study of the reaction of the vitamin B

Randomised controlled trial of two sequential artemisinin-based combination therapy regimens to treat uncomplicated falciparum malaria in African children: a protocol to investigate safety, efficacy and adherence.

BMJ global health

Schallig HD, Tinto H, Sawa P, Kaur H, Duparc S, Ishengoma DS, Magnussen P, Alifrangis M, Sutherland CJ.
PMID: 29082016
BMJ Glob Health. 2017 Aug 30;2(3):e000371. doi: 10.1136/bmjgh-2017-000371. eCollection 2017.

BACKGROUND: Management of uncomplicated METHODS: We present an open-label, randomised three-arm clinical trial protocol in three African settings representative of varying malaria epidemiology to investigate whether prolonged ACT-based regimens using currently available formulations can eliminate potentially resistant parasites. The...

Concurrence in the ability for lipid synthesis between life stages in insects.

Royal Society open science

Visser B, Willett DS, Harvey JA, Alborn HT.
PMID: 28405368
R Soc Open Sci. 2017 Mar 22;4(3):160815. doi: 10.1098/rsos.160815. eCollection 2017 Mar.

The ability to synthesize lipids is critical for an organism's fitness; hence, metabolic pathways, underlying lipid synthesis, tend to be highly conserved. Surprisingly, the majority of parasitoids deviate from this general metabolic model by lacking the ability to convert...

Intervalltherapie mit Vemurafenib beim malignen Melanom.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

Treiber N, Huber MA, Schneider LA, Scharffetter-Kochanek K, Schultz E, Debus D.
PMID: 28378474
J Dtsch Dermatol Ges. 2017 Apr;15(4):450-453. doi: 10.1111/ddg.13034_g.

No abstract available.

Combination of Photon and Carbon Ion Irradiation with Targeted Therapy Substances Temsirolimus and Gemcitabine in Hepatocellular Carcinoma Cell Lines.

Frontiers in oncology

Dehne S, Fritz C, Rieken S, Baris D, Brons S, Haberer T, Debus J, Weber KJ, Schmid TE, Combs SE, Habermehl D.
PMID: 28348976
Front Oncol. 2017 Mar 13;7:35. doi: 10.3389/fonc.2017.00035. eCollection 2017.

BACKGROUND: This work investigates on putative cytotoxic effects in four different hepatocellular carcinoma (HCC) cell lines after irradiation with photons or carbon ions in combination with new targeted molecular therapy using either Temsirolimus (TEM) or Gemcitabine (GEM).METHODS AND MATERIALS:...

Selective functionalization of methylene bridges of calix[6]arenes. Isolation and identification of stable conformers of methyl ether of p-tert-butylcalix[6]arene.

Chemical communications (Cambridge, England)

Arora S, Sharma S, Mithu VS, Hee-Lee C, Singh K.
PMID: 25670155
Chem Commun (Camb). 2015 Mar 11;51(20):4227-30. doi: 10.1039/c4cc10400e.

Direct disubstitution at the methylene bridges of p-tert-butylcalix[6]arenemethyl ether has been achieved for the first time using a lithiation-substitution protocol. Two stable conformers have been isolated using column chromatography, and their structures have been unambiguously confirmed from 1D, 2D...

Probing highly confined optical fields in the focal region of a high NA parabolic mirror with subwavelength spatial resolution.

Journal of microscopy

Debus C, Lieb MA, Drechsler A, Meixner AJ.
PMID: 12787085
J Microsc. 2003 Jun;210:203-8. doi: 10.1046/j.1365-2818.2003.01091.x.

Parabolic mirrors with a high numerical aperture can be conveniently used to produce highly confined optical fields in the focal region. Furthermore, these fields can have interesting polarization behaviour due to the high numerical aperture. In particular, if the...

Showing 1 to 12 of 593 entries