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Showing 1 to 12 of 595 entries
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A Chemical Probe for the ATAD2 Bromodomain.

Angewandte Chemie (International ed. in English)

Bamborough P, Chung CW, Demont EH, Furze RC, Bannister AJ, Che KH, Diallo H, Douault C, Grandi P, Kouzarides T, Michon AM, Mitchell DJ, Prinjha RK, Rau C, Robson S, Sheppard RJ, Upton R, Watson RJ.
PMID: 27530368
Angew Chem Int Ed Engl. 2016 Sep 12;55(38):11382-6. doi: 10.1002/anie.201603928. Epub 2016 Aug 17.

ATAD2 is a cancer-associated protein whose bromodomain has been described as among the least druggable of that target class. Starting from a potent lead, permeability and selectivity were improved through a dual approach: 1) using CF2 as a sulfone...

New microbes and new infections

Pham TP, Cadoret F, Alou MT, Brah S, Diallo BA, Diallo A, Sokhna C, Delerce J, Fournier PE, Million M, Raoult D.
PMID: 28392924
New Microbes New Infect. 2017 Mar 03;17:84-88. doi: 10.1016/j.nmni.2017.02.004. eCollection 2017 May.

We report here the main characteristics of five new species

Extensive genomic variability of knops blood group polymorphisms is associated with sickle cell disease in Africa.

Evolutionary bioinformatics online

Duru KC, Noble JA, Guindo A, Yi L, Imumorin IG, Diallo DA, Thomas BN.
PMID: 25788827
Evol Bioinform Online. 2015 Mar 09;11:25-33. doi: 10.4137/EBO.S23132. eCollection 2015.

Sickle cell disease (SCD) is a multisystem disorder characterized by chronic hemolytic anemia, vaso-occlusive crises, and marked variability in disease severity. Patients require transfusions to manage disease complications, with complements, directed by complement regulatory genes (CR1) and its polymorphisms,...

HIV and Tuberculosis co-infection impacts T-cell activation markers but not the numbers subset of regulatory T-cells in HIV-1 infected patients.

African journal of laboratory medicine

Mbow M, Santos NSS, Camara M, Ba A, Niang A, Daneau G, Wade D, Diallo AA, Toupane M, Diakhaté M, Lèye N, Diaw PA, Mboup S, Kestens L, Dieye TN.
PMID: 29043167
Afr J Lab Med. 2013 Sep 02;2(1):76. doi: 10.4102/ajlm.v2i1.76. eCollection 2013.

BACKGROUND: Tuberculosis (TB) has been shown to accelerate the clinical course of HIV infection, but the mechanisms by which this occurs are not well understood. Regulatory T-cells (Tregs) are known to dampen hyperactivation of the immune cells, but it...

Endothelin-1 but not Endothelial Nitric Oxide Synthase Gene Polymorphism is Associated with Sickle Cell Disease in Africa.

Gene regulation and systems biology

Thakur TJ, Guindo A, Cullifer LR, Li Y, Imumorin IG, Diallo DA, Thomas BN.
PMID: 24932102
Gene Regul Syst Bio. 2014 May 25;8:119-26. doi: 10.4137/GRSB.S14836. eCollection 2014.

Sickle cell disease shows marked variability in severity and pathophysiology among individuals, probably linked to differential expression of various adhesion molecules. In this study, we investigated the differential distribution, genomic diversity and haplotype frequency of endothelial nitric oxide synthase...

Biotransformation enzyme activities in the olfactory organ of rainbow trout (Oncorhynchus mykiss). Immunocytochemical localization of cytochrome P4501A1 and its induction by β-naphthoflavone.

Fish physiology and biochemistry

Monod G, Saucier D, Perdu-Durand E, Diallo M, Cravedi JP, Astic L.
PMID: 24197139
Fish Physiol Biochem. 1994 Dec;13(6):433-44. doi: 10.1007/BF00004326.

Olfaction is a crucial function in most fish species, but little is known about biotransformation enzymes in the olfactory organ. This study demonstrates that biotransformation enzymes usually found in the rainbow trout liver, are present in the olfactory organ...

The little volcanoes that could.

Scientific American

Biello D.
PMID: 24783580
Sci Am. 2014 May;310(5):16. doi: 10.1038/scientificamerican0514-16.

No abstract available.

Noncontiguous finished genome sequence and description of Weeksella massiliensis sp. nov.

New microbes and new infections

Sankar SA, Lo CI, Fall B, Sambe-Ba B, Mediannikov O, Diallo I, Labas N, Faye N, Wade B, Raoult D, Fournier PE, Fenollar F.
PMID: 26649182
New Microbes New Infect. 2015 Oct 02;8:89-98. doi: 10.1016/j.nmni.2015.09.013. eCollection 2015 Nov.

Strain FF8(T) (= CSUR P860 = DSM 28259) was isolated in Dakar, Senegal, from the urine of a 65-year-old man with acute cystitis. This strain shows a similarity of sequence of 16S rRNA of 98.38% with Weeksella virosa, and...

Crystal structure of di-methyl-ammonium hydrogen oxalate hemi(oxalic acid).

Acta crystallographica. Section E, Crystallographic communications

Diallo W, Gueye N, Crochet A, Plasseraud L, Cattey H.
PMID: 25995858
Acta Crystallogr E Crystallogr Commun. 2015 Apr 11;71:473-5. doi: 10.1107/S2056989015005964. eCollection 2015 May 01.

Single crystals of the title salt, Me2NH2 (+)·HC2O4 (-)·0.5H2C2O4, were isolated as a side product from the reaction involving Me2NH, H2C2O4 and Sn(n-Bu)3Cl in a 1:2 ratio in methanol or by the reaction of the (Me2NH2)2C2O4 salt and Sn(CH3)3Cl...

First report and characterization of peste des petits ruminants virus in Liberia, West Africa.

Tropical animal health and production

Boussini H, Chitsungo E, Bodjo SC, Diakite A, Nwankpa N, Elsawalhy A, Anderson JR, Diallo A, Dundon WG.
PMID: 27315206
Trop Anim Health Prod. 2016 Oct;48(7):1503-7. doi: 10.1007/s11250-016-1101-y. Epub 2016 Jun 17.

No abstract available.

Polyploidy can Confer Superiority to West African Acacia senegal (L.) Willd. Trees.

Frontiers in plant science

Diallo AM, Nielsen LR, Kjær ED, Petersen KK, Ræbild A.
PMID: 27379120
Front Plant Sci. 2016 Jun 14;7:821. doi: 10.3389/fpls.2016.00821. eCollection 2016.

Polyploidy is a common phenomenon in the evolution of angiosperms. It has been suggested that polyploids manage harsh environments better than their diploid relatives but empirical data supporting this hypothesis are scarce, especially for trees. Using microsatellite markers and...

Giant thermo-optical relaxation oscillations in millimeter-size whispering gallery mode disk resonators.

Optics letters

Diallo S, Lin G, Chembo YK.
PMID: 26274672
Opt Lett. 2015 Aug 15;40(16):3834-7. doi: 10.1364/OL.40.003834.

In this Letter, we show that giant thermo-optical oscillations can be triggered in millimeter (mm)-size whispering gallery mode (WGM) disk resonators when they are pumped by a resonant continuous-wave laser. Our resonator is an ultrahigh-Q barium fluoride cavity that...

Showing 1 to 12 of 595 entries