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Showing 1 to 9 of 9 entries
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Increased level of phosphorylated desmin and its degradation products in heart failure.

Biochemistry and biophysics reports

Bouvet M, Dubois-Deruy E, Alayi TD, Mulder P, El Amranii M, Beseme O, Amouyel P, Richard V, Tomavo S, Pinet F.
PMID: 28955862
Biochem Biophys Rep. 2016 Feb 27;6:54-62. doi: 10.1016/j.bbrep.2016.02.014. eCollection 2016 Jul.

Although several risk factors such as infarct size have been identified, the progression/severity of heart failure (HF) remains difficult to predict in clinical practice. Using an experimental rat model of ischemic HF and phosphoproteomic technology, we found an increased...

A New Strategy to Preserve and Assess Oxygen Consumption in Murine Tissues.

International journal of molecular sciences

Kluza J, Peugnet V, Daunou B, Laine W, Kervoaze G, Rémy G, Loyens A, Maboudou P, Fovez Q, Grangette C, Wolowczuk I, Gosset P, Garçon G, Marchetti P, Pinet F, Pichavant M, Dubois-Deruy E.
PMID: 35008535
Int J Mol Sci. 2021 Dec 22;23(1). doi: 10.3390/ijms23010109.

Mitochondrial dysfunctions are implicated in several pathologies, such as metabolic, cardiovascular, respiratory, and neurological diseases, as well as in cancer and aging. These metabolic alterations are usually assessed in human or murine samples by mitochondrial respiratory chain enzymatic assays,...

A New Strategy to Preserve and Assess Oxygen Consumption in Murine Tissues.

International journal of molecular sciences

Kluza J, Peugnet V, Daunou B, Laine W, Kervoaze G, Rémy G, Loyens A, Maboudou P, Fovez Q, Grangette C, Wolowczuk I, Gosset P, Garçon G, Marchetti P, Pinet F, Pichavant M, Dubois-Deruy E.
PMID: 35008535
Int J Mol Sci. 2021 Dec 22;23(1). doi: 10.3390/ijms23010109.

Mitochondrial dysfunctions are implicated in several pathologies, such as metabolic, cardiovascular, respiratory, and neurological diseases, as well as in cancer and aging. These metabolic alterations are usually assessed in human or murine samples by mitochondrial respiratory chain enzymatic assays,...

Desmin aggrephagy in rat and human ischemic heart failure through PKCζ and GSK3β as upstream signaling pathways.

Cell death discovery

Bouvet M, Dubois-Deruy E, Turkieh A, Mulder P, Peugnet V, Chwastyniak M, Beseme O, Dechaumes A, Amouyel P, Richard V, Lamblin N, Pinet F.
PMID: 34226534
Cell Death Discov. 2021 Jun 26;7(1):153. doi: 10.1038/s41420-021-00549-2.

Post-translational modifications of cardiac proteins could participate to left contractile dysfunction resulting in heart failure. Using a rat model of ischemic heart failure, we showed an accumulation of phosphorylated desmin leading to toxic aggregates in cardiomyocytes, but the cellular...

Erratum: Rémy et al. Modelling the Impact of Chronic Cigarette Smoke Exposure in Obese Mice: Metabolic, Pulmonary, Intestinal, and Cardiac Issues. .

Nutrients

Rémy G, Dubois-Deruy E, Alard J, Kervoaze G, Chwastyniak M, Baron M, Beury D, Siegwald L, Caboche S, Hot D, Gosset P, Grangette C, Pinet F, Wolowczuk I, Pichavant M.
PMID: 34579176
Nutrients. 2021 Sep 02;13(9). doi: 10.3390/nu13093084.

The authors have requested that the following changes be made to their paper [...].

Publisher Correction: MicroRNAs regulating superoxide dismutase 2 are new circulating biomarkers of heart failure.

Scientific reports

Dubois-Deruy E, Cuvelliez M, Fiedler J, Charrier H, Mulder P, Hebbar E, Pfanne A, Beseme O, Chwastyniak M, Amouyel P, Richard V, Bauters C, Thum T, Pinet F.
PMID: 30498227
Sci Rep. 2018 Nov 29;8(1):17584. doi: 10.1038/s41598-018-35955-7.

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.

Interplay Between Phosphorylation and O-GlcNAcylation of Sarcomeric Proteins in Ischemic Heart Failure.

Frontiers in endocrinology

Mercier T, Bouvet M, Dubois-Deruy E, Dechaumes A, Beseme O, Richard V, Mulder P, Pinet F.
PMID: 30344511
Front Endocrinol (Lausanne). 2018 Oct 05;9:598. doi: 10.3389/fendo.2018.00598. eCollection 2018.

Post-translational modifications (PTMs) of sarcomeric proteins could participate to left ventricular (LV) remodeling and contractile dysfunction leading in advanced heart failure (HF) with altered ejection fraction. Using an experimental rat model of HF (ligation of left coronary artery) and...

Integrative System Biology Analyses Identify Seven MicroRNAs to Predict Heart Failure.

Non-coding RNA

Charrier H, Cuvelliez M, Dubois-Deruy E, Mulder P, Richard V, Bauters C, Pinet F.
PMID: 30866581
Noncoding RNA. 2019 Mar 07;5(1). doi: 10.3390/ncrna5010022.

Heart failure (HF) has several etiologies including myocardial infarction (MI) and left ventricular remodeling (LVR), but its progression remains difficult to predict in clinical practice. Systems biology analyses of LVR after MI provide molecular insights into this event such...

Oxidative Stress in Cardiovascular Diseases.

Antioxidants (Basel, Switzerland)

Dubois-Deruy E, Peugnet V, Turkieh A, Pinet F.
PMID: 32937950
Antioxidants (Basel). 2020 Sep 14;9(9). doi: 10.3390/antiox9090864.

Reactive oxygen species (ROS) are subcellular messengers in signal transductions pathways with both beneficial and deleterious roles. ROS are generated as a by-product of mitochondrial respiration or metabolism or by specific enzymes such as superoxide dismutases, glutathione peroxidase, catalase,...

Showing 1 to 9 of 9 entries