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Showing 1 to 12 of 58 entries
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Galectin-3 and Venous Thromboembolism Incidence: the Atherosclerosis Risk in Communities (ARIC) Study.

Research and practice in thrombosis and haemostasis

Fashanu OE, Heckbert SR, Aguilar D, Jensen PN, Ballantyne CM, Basu S, Hoogeveen RC, deFilippi C, Cushman M, Folsom AR.
PMID: 29152608
Res Pract Thromb Haemost. 2017 Oct;1(2):223-230. doi: 10.1002/rth2.12038. Epub 2017 Sep 04.

BACKGROUND: The inflammatory biomarker galectin-3 contributes to pathologic conditions such as heart failure and stimulates murine thrombogenesis. Its association with venous thromboembolism (VTE) has been sparsely studied.OBJECTIVES: To assess the prospective association of plasma galectin-3 and the METHODS: We...

A Synthesis of Current Surveillance Planning Methods for the Sequential Monitoring of Drug and Vaccine Adverse Effects Using Electronic Health Care Data.

EGEMS (Washington, DC)

Nelson JC, Wellman R, Yu O, Cook AJ, Maro JC, Ouellet-Hellstrom R, Boudreau D, Floyd JS, Heckbert SR, Pinheiro S, Reichman M, Shoaibi A.
PMID: 27713904
EGEMS (Wash DC). 2016 Sep 06;4(1):1219. doi: 10.13063/2327-9214.1219. eCollection 2016.

INTRODUCTION: The large-scale assembly of electronic health care data combined with the use of sequential monitoring has made proactive postmarket drug- and vaccine-safety surveillance possible. Although sequential designs have been used extensively in randomized trials, less attention has been...

Incremental value of rare genetic variants for the prediction of multifactorial diseases.

Genome medicine

Mihaescu R, Pencina MJ, Alonso A, Lunetta KL, Heckbert SR, Benjamin EJ, Janssens AC.
PMID: 23961719
Genome Med. 2013 Aug 20;5(8):76. doi: 10.1186/gm480. eCollection 2013.

BACKGROUND: It is often assumed that rare genetic variants will improve available risk prediction scores. We aimed to estimate the added predictive ability of rare variants for risk prediction of common diseases in hypothetical scenarios.METHODS: In simulated data, we...

Hospital and clinical care costs associated with atrial fibrillation for Medicare beneficiaries in the Cardiovascular Health Study and the Framingham Heart Study.

SAGE open medicine

Delaney JA, Yin X, Fontes JD, Wallace ER, Skinner A, Wang N, Hammill BG, Benjamin EJ, Curtis LH, Heckbert SR.
PMID: 29511541
SAGE Open Med. 2018 Feb 20;6:2050312118759444. doi: 10.1177/2050312118759444. eCollection 2018.

BACKGROUND: Atrial fibrillation is increasingly prevalent as the US population ages and is associated with significant morbidity and mortality. Care for patients with atrial fibrillation can be costly, US health care costs are comparatively high, and there are few...

Biomarkers, menopausal hormone therapy and risk of venous thrombosis: The Women's Health Initiative.

Research and practice in thrombosis and haemostasis

Cushman M, Larson JC, Rosendaal FR, Heckbert SR, Curb JD, Phillips LS, Baird AE, Eaton CB, Stafford RS.
PMID: 30046733
Res Pract Thromb Haemost. 2018 Apr 17;2(2):310-319. doi: 10.1002/rth2.12100. eCollection 2018 Apr.

BACKGROUND: Oral menopausal hormone therapy causes venous thrombosis but whether biomarkers of thrombosis risk can identify women at risk is unknown.METHODS: We completed a nested case control study in the two Women's Health Initiative hormone trials; 27 347 women...

Insomnia and Risk of Myocardial Infarction Among People with HIV.

Journal of acquired immune deficiency syndromes (1999)

Luu BR, Nance RM, Delaney JAC, Ruderman SA, Heckbert SR, Budoff MJ, Mathews WC, Moore RD, Feinstein MJ, Burkholder GA, Eron JJ, Mugavero MJ, Saag MS, Kitahata MM, Crane HM, Whitney BM.
PMID: 35001042
J Acquir Immune Defic Syndr. 2022 Jan 06; doi: 10.1097/QAI.0000000000002910. Epub 2022 Jan 06.

BACKGROUND: Insomnia is common among people with HIV (PWH) and may be associated with increased risk of myocardial infarction (MI). This study examines the association between insomnia and MI by MI type among PWH.SETTING: Longitudinal cohort study of PWH...

Early Cumulative Fluid Balance and Outcomes in Pediatric Allogeneic Hematopoietic Cell Transplant Recipients With Acute Respiratory Failure: A Multicenter Study.

Frontiers in oncology

Sallee CJ, Smith LS, Rowan CM, Heckbert SR, Angelo JR, Daniel MC, Gertz SJ, Hsing DD, Mahadeo KM, McArthur JA, Fitzgerald JC.
PMID: 34354951
Front Oncol. 2021 Jul 20;11:705602. doi: 10.3389/fonc.2021.705602. eCollection 2021.

OBJECTIVES: To evaluate the associations between early cumulative fluid balance (CFB) and outcomes among critically ill pediatric allogeneic hematopoietic cell transplant (HCT) recipients with acute respiratory failure, and determine if these associations vary by treatment with renal replacement therapy...

Intermittent Nonhabitual Coffee Consumption and Risk of Atrial Fibrillation: The Multi-Ethnic Study of Atherosclerosis.

Journal of atrial fibrillation

Xu J, Fan W, Budoff MJ, Heckbert SR, Amsterdam EA, Alonso A, Wong ND.
PMID: 31687073
J Atr Fibrillation. 2019 Jun 30;12(1):2205. doi: 10.4022/jafib.2205. eCollection 2019 Jun.

BACKGROUND: Though it is a widely held belief that caffeinated beverages predispose individuals to arrhythmias, it is not clear whether regular coffee consumption is associated with development of atrial fibrillation (AF).OBJECTIVE: We examined the association between long-term coffee consumption...

Individual non-esterified fatty acids and incident atrial fibrillation late in life.

Heart (British Cardiac Society)

Pellegrini CN, Buzkova P, Lichtenstein AH, Matthan NR, Ix JH, Siscovick DS, Heckbert SR, Tracy RP, Mukamal KJ, Djoussé L, Kizer JR.
PMID: 33483356
Heart. 2021 Nov;107(22):1805-1812. doi: 10.1136/heartjnl-2020-317929. Epub 2021 Jan 22.

OBJECTIVE: Obesity and dysmetabolism are major risk factors for atrial fibrillation (AF). Expansion of fat depots is associated with increased circulating total non-esterified fatty acids (NEFAs), elevated levels of which are associated with incident AF. We undertook comprehensive serum...

Intermediate Markers Underlying Electrocardiographic Predictors of Incident Atrial Fibrillation: The MESA.

Circulation. Arrhythmia and electrophysiology

Xie E, Wu C, Ostovaneh M, Post WS, Kutty S, Soliman EZ, Bluemke DA, Heckbert SR, Lima J, Ambale-Venkatesh B.
PMID: 34844442
Circ Arrhythm Electrophysiol. 2021 Dec;14(12):e009805. doi: 10.1161/CIRCEP.121.009805. Epub 2021 Nov 30.

No abstract available.

Epigenetic Age and the Risk of Incident Atrial Fibrillation.

Circulation

Roberts JD, Vittinghoff E, Lu AT, Alonso A, Wang B, Sitlani CM, Mohammadi-Shemirani P, Fornage M, Kornej J, Brody JA, Arking DE, Lin H, Heckbert SR, Prokic I, Ghanbari M, Skanes AC, Bartz TM, Perez MV, Taylor KD, Lubitz SA, Ellinor PT, Lunetta KL, Pankow JS, Paré G, Sotoodehnia N, Benjamin EJ, Horvath S, Marcus GM.
PMID: 34587750
Circulation. 2021 Dec 14;144(24):1899-1911. doi: 10.1161/CIRCULATIONAHA.121.056456. Epub 2021 Sep 30.

BACKGROUND: The most prominent risk factor for atrial fibrillation (AF) is chronological age; however, underlying mechanisms are unexplained. Algorithms using epigenetic modifications to the human genome effectively predict chronological age. Chronological and epigenetic predicted ages may diverge in a...

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk.

Nature communications

Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, Hwang SJ, Jaju D, Kerr KF, Kluttig A, Krijthe BP, Kumar J, van der Laan SW, Lyytikäinen LP, Maihofer AX, Minassian A, van der Most PJ, Müller-Nurasyid M, Nivard M, Salvi E, Stewart JD, Thayer JF, Verweij N, Wong A, Zabaneh D, Zafarmand MH, Abdellaoui A, Albarwani S, Albert C, Alonso A, Ashar F, Auvinen J, Axelsson T, Baker DG, de Bakker PIW, Barcella M, Bayoumi R, Bieringa RJ, Boomsma D, Boucher G, Britton AR, Christophersen I, Dietrich A, Ehret GB, Ellinor PT, Eskola M, Felix JF, Floras JS, Franco OH, Friberg P, Gademan MGJ, Geyer MA, Giedraitis V, Hartman CA, Hemerich D, Hofman A, Hottenga JJ, Huikuri H, Hutri-Kähönen N, Jouven X, Junttila J, Juonala M, Kiviniemi AM, Kors JA, Kumari M, Kuznetsova T, Laurie CC, Lefrandt JD, Li Y, Li Y, Liao D, Limacher MC, Lin HJ, Lindgren CM, Lubitz SA, Mahajan A, McKnight B, Zu Schwabedissen HM, Milaneschi Y, Mononen N, Morris AP, Nalls MA, Navis G, Neijts M, Nikus K, North KE, O'Connor DT, Ormel J, Perz S, Peters A, Psaty BM, Raitakari OT, Risbrough VB, Sinner MF, Siscovick D, Smit JH, Smith NL, Soliman EZ, Sotoodehnia N, Staessen JA, Stein PK, Stilp AM, Stolarz-Skrzypek K, Strauch K, Sundström J, Swenne CA, Syvänen AC, Tardif JC, Taylor KD, Teumer A, Thornton TA, Tinker LE, Uitterlinden AG, van Setten J, Voss A, Waldenberger M, Wilhelmsen KC, Willemsen G, Wong Q, Zhang ZM, Zonderman AB, Cusi D, Evans MK, Greiser HK, van der Harst P, Hassan M, Ingelsson E, Järvelin MR, Kääb S, Kähönen M, Kivimaki M, Kooperberg C, Kuh D, Lehtimäki T, Lind L, Nievergelt CM, O'Donnell CJ, Oldehinkel AJ, Penninx B, Reiner AP, Riese H, van Roon AM, Rioux JD, Rotter JI, Sofer T, Stricker BH, Tiemeier H, Vrijkotte TGM, Asselbergs FW, Brundel BJJM, Heckbert SR, Whitsel EA, den Hoed M, Snieder H, de Geus EJC.
PMID: 28767105
Nat Commun. 2017 Aug 02;8:16140. doi: 10.1038/ncomms16140.

This corrects the article DOI: 10.1038/ncomms15805.

Showing 1 to 12 of 58 entries