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Showing 1 to 12 of 589 entries
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The expression of IGF-1R in Helicobacter pylori-infected intestinal metaplasia and gastric cancer.

Journal of clinical biochemistry and nutrition

Nakajima N, Kozu K, Kobayashi S, Nishiyama R, Okubo R, Akai Y, Moriyama M, Kinukawa N.
PMID: 27499580
J Clin Biochem Nutr. 2016 Jul;59(1):53-7. doi: 10.3164/jcbn.16-11. Epub 2016 May 21.

Overexpression of IGF-1R has been demonstrated in gastrointestinal cancers, and its expression is reported as the result of the loss of tumor suppressors. IL-16 is involved in the pathophysiological process of chronic inflammatory diseases. The aim of this study...

Novel SLC16A2 mutations in patients with Allan-Herndon-Dudley syndrome.

Intractable & rare diseases research

Shimojima K, Maruyama K, Kikuchi M, Imai A, Inoue K, Yamamoto T.
PMID: 27672545
Intractable Rare Dis Res. 2016 Aug;5(3):214-7. doi: 10.5582/irdr.2016.01051.

Allan-Herndon-Dudley syndrome (AHDS) is an X-linked disorder caused by impaired thyroid hormone transporter. Patients with AHDS usually exhibit severe motor developmental delay, delayed myelination of the brain white matter, and elevated T3 levels in thyroid tests. Neurological examination of...

Tapentadol extended release in the management of peripheral diabetic neuropathic pain.

Therapeutics and clinical risk management

Vadivelu N, Kai A, Maslin B, Kodumudi G, Legler A, Berger JM.
PMID: 25609974
Ther Clin Risk Manag. 2015 Jan 14;11:95-105. doi: 10.2147/TCRM.S32193. eCollection 2015.

Tapentadol, a μ-opioid agonist and norepinephrine reuptake inhibitor, has been found to be an effective medication for a wide variety of chronic pain conditions, including back pain, cancer-related pain, and arthritic pain. It has also been found to have...

Salvage Brachytherapy for Castration-Resistant and External Beam Radiotherapy-Resistant Local Recurrence 17 Years after Radical Prostatectomy.

Case reports in urology

Hosogoe S, Soma O, Matsumoto T, Imai A, Hatakeyama S, Yoneyama T, Hashimoto Y, Koie T, Ohyama C, Aoki M.
PMID: 26171272
Case Rep Urol. 2015;2015:839738. doi: 10.1155/2015/839738. Epub 2015 Jun 11.

A 47-year-old Japanese man was diagnosed with prostate cancer in February 1995 (Initial PSA 77.2 ng/mL, GS3 + 4, cT3N0M0). He underwent radical prostatectomy after androgen deprivation therapy (ADT) in June 1995. Nine years after operation, he was diagnosed...

Significance of renal biopsy in patients with presumed diabetic nephropathy.

Journal of diabetes investigation

Harada K, Akai Y, Sumida K, Yoshikawa M, Takahashi H, Yamaguchi Y, Kubo A, Iwano M, Saito Y.
PMID: 24843636
J Diabetes Investig. 2013 Jan 29;4(1):88-93. doi: 10.1111/j.2040-1124.2012.00233.x. Epub 2012 Aug 10.

AIMS/INTRODUCTION: Patients with diabetic nephropathy (DN) typically show varying degrees of proteinuria and renal impairment. Because these clinical signs are frequently observed in other glomerulopathies, renal biopsy is required to make a definitive diagnosis of DN. We carried out...

Student use and pedagogical impact of a mobile learning application.

Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology

Teri S, Acai A, Griffith D, Mahmoud Q, Ma DW, Newton G.
PMID: 24375862
Biochem Mol Biol Educ. 2014 Mar-Apr;42(2):121-35. doi: 10.1002/bmb.20771. Epub 2013 Dec 20.

Mobile learning (m-learning) is a relevant innovation in teaching and learning in higher education. A mobile app called NutriBiochem was developed for use in biochemistry and nutrition education for students in a second year Biochemistry and Metabolism course. NutriBiochem...

Assembly of the mitochondrial membrane system. Organization of yeast mitochondrial DNA in the Oli1 region.

Current genetics

Tzagoloff A, Nobrega M, Akail A, Macino G.
PMID: 24189806
Curr Genet. 1980 Oct;2(2):149-57. doi: 10.1007/BF00420627.

The mitochondrial DNA (mtDNA) of a cytoplasmic petite mutant (DS401) of Saccharomyces cerevisiae genetically marked for the ATPase proteolipid, serine tRNA and varl genes has been characterized by restriction endonuclease analysis and DNA sequencing. The DS401 mtDNA segment is...

Correlations between developmental capacity and structure of tissue sublines derived from the eye-antennal imaginal disc ofDrosophila melanogaster.

Wilhelm Roux' Archiv fur Entwicklungsmechanik der Organismen

Gateff E, Akai H, Schneiderman HA.
PMID: 28304837
Wilhelm Roux Arch Entwickl Mech Org. 1974 Dec;176(2):89-123. doi: 10.1007/BF02569022.

Developmental capacities of imaginal disc tissue sublines were correlated with their growth rate, morphology, histology and fine structure. Tissue sublines were derived from half an eye-antennal disc ofDrosophila melanogaster and were serially subculturedin vivo in the abdomens of adult...

A case of primary renal carcinoid tumor.

Case reports in urology

Tanaka T, Yamamoto H, Imai A, Shingo H, Yoneyama T, Koie T, Hashimoto Y, Ohyama C.
PMID: 25685590
Case Rep Urol. 2015;2015:736213. doi: 10.1155/2015/736213. Epub 2015 Jan 22.

Primary renal carcinoid tumors are extremely rare kidney lesions, with fewer than 100 reported cases previously. We describe a 75-year-old man with an incidentally detected cystic renal mass. Computed tomography showed a 3 cm tumor with a cystic component...

Dual activation by lisuride of central serotonin 5-HT(1A) and dopamine D(2) receptor sites: drug discrimination and receptor binding studies.

Behavioural pharmacology

Kimura K, Akai T, Nakamura K, Yamaguchi M, Nakagawa H, Oshino N.
PMID: 11224054
Behav Pharmacol. 1991 Apr;2(2):105-112.

To investigate central serotonergic (5-HT) and dopaminergic (DA) actions of lisuride, the discriminative properties of lisuride (0.05mg/kg, i.p.) in rats were investigated, in addition to the radioligand binding of the compound to 5-HT and DA receptor subtypes. Lisuride was...

Enhancement of nitric oxide generation by low frequency electromagnetic field.

Pathophysiology : the official journal of the International Society for Pathophysiology

Yoshikawa T, Tanigawa M, Tanigawa T, Imai A, Hongo H, Kondo M.
PMID: 10927193
Pathophysiology. 2000 Jul;7(2):131-135. doi: 10.1016/s0928-4680(00)00040-7.

Oxidative stress is implicated in the intracellular signal transduction pathways for nitric oxide synthase (NOS) induction. The electromagnetic field (EMF) is believed to increase the free radical lifespan [S. Roy, Y. Noda, V. Eckert, M.G. Traber, A. Mori, R....

Gonadotropin-releasing hormone stimulates phospholipase C but not protein phosphorylation/dephosphorylation in plasma membrane from human epithelial ovarian cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Imai A, Ohno T, Furui T, Takahashi K, Matsuda T, Tamaya T.
PMID: 11578363
Int J Gynecol Cancer. 1993 Sep;3(5):311-317. doi: 10.1046/j.1525-1438.1993.03050311.x.

In view of advances in treatment of certain hormone-dependent cancers with analogues of gonadotropin-releasing hormone (Gn-RH), this study was undertaken to establish the signal transduction events interacting with Gn-RH receptor in a cell-free system prepared from human ovarian mucinous...

Showing 1 to 12 of 589 entries