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Design thinking in digital innovation projects—Exploring the effects of intangibility

teaching innovation

Klinker K, Przybilla L.
GSID: JHvXw8wXiOQJ
L Przybilla, K Klinker, M Lang… - IEEE Transactions …, 2020 - ieeexplore.ieee.org

The locus of innovation has shifted from mechanical advances to digital solutions. By emphasizing the importance of user needs, Design Thinking is apt to develop human …

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Przybilla, L., Klinker, K., Lang, M., Schreieck, M., Wiesche, M., & Krcmar, H. (2020). Design thinking in digital innovation projects—Exploring the effects of intangibility. IEEE Transactions on Engineering Management.
Przybilla, Leonard, et al. "Design thinking in digital innovation projects—Exploring the effects of intangibility." IEEE Transactions on Engineering Management (2020).
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[The most significant items for the pediatrician from the 1964 German literature].

Kinderarztliche Praxis

Klinke K.
PMID: 5332670
Kinderarztl Prax. 1966 Aug;34(8):375-80 contd.

No abstract available.

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Klinke K. Das für den Kinderarzt Wichtigste aus dem deutschen Schrifttum des Jahres 1964. [The most significant items for the pediatrician from the 1964 German literature]. Kinderarztl Prax. 1966;34(8):375-80 contd
Klinke, K. (1966). Das für den Kinderarzt Wichtigste aus dem deutschen Schrifttum des Jahres 1964. [The most significant items for the pediatrician from the 1964 German literature]. Kinderarztliche Praxis, 34(8), 375-80 contd.
Klinke, K. "Das für den Kinderarzt Wichtigste aus dem deutschen Schrifttum des Jahres 1964." [The most significant items for the pediatrician from the 1964 German literature]. Kinderarztliche Praxis vol. 34,8 (1966): 375-80 contd.
Klinke K. Das für den Kinderarzt Wichtigste aus dem deutschen Schrifttum des Jahres 1964. [The most significant items for the pediatrician from the 1964 German literature]. Kinderarztl Prax. 1966 Aug;34(8):375-80 contd. German. PMID: 5332670.
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Antimicrobial Stewardship in the Emergency Department.

Infectious diseases and therapy

Trinh TD, Klinker KP.
PMID: 26362293
Infect Dis Ther. 2015 Sep;4:39-50. doi: 10.1007/s40121-015-0084-8. Epub 2015 Sep 11.

The literature contains robust evidence on the positive impact of antimicrobial stewardship programs (ASP) in the inpatient setting. With national policies shifting toward provisions of quality health care, the impetus to expand ASP services becomes an important strategy for...

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Trinh TD, Klinker KP. Antimicrobial Stewardship in the Emergency Department. Infect Dis Ther. 2015;4:39-50doi: 10.1007/s40121-015-0084-8.
Trinh, T. D., & Klinker, K. P. (2015). Antimicrobial Stewardship in the Emergency Department. Infectious diseases and therapy, 439-50. https://doi.org/10.1007/s40121-015-0084-8
Trinh, Trang D, and Klinker, Kenneth P. "Antimicrobial Stewardship in the Emergency Department." Infectious diseases and therapy vol. 4 (2015): 39-50. doi: https://doi.org/10.1007/s40121-015-0084-8
Trinh TD, Klinker KP. Antimicrobial Stewardship in the Emergency Department. Infect Dis Ther. 2015 Sep;4:39-50. doi: 10.1007/s40121-015-0084-8. Epub 2015 Sep 11. PMID: 26362293; PMCID: PMC4569640.
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Acousto-optic pulse picking scheme with carrier-frequency-to-pulse-repetition-rate synchronization.

Optics express

de Vries O, Saule T, Plötner M, Lücking F, Eidam T, Hoffmann A, Klenke A, Hädrich S, Limpert J, Holzberger S, Schreiber T, Eberhardt R, Pupeza I, Tünnermann A.
PMID: 26367616
Opt Express. 2015 Jul 27;23(15):19586-95. doi: 10.1364/OE.23.019586.

We introduce and experimentally validate a pulse picking technique based on a travelling-wave-type acousto-optic modulator (AOM) having the AOM carrier frequency synchronized to the repetition rate of the original pulse train. As a consequence, the phase noise characteristic of...

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de Vries O, Saule T, Plötner M, et al. Acousto-optic pulse picking scheme with carrier-frequency-to-pulse-repetition-rate synchronization. Opt Express. 2015;23(15):19586-95doi: 10.1364/OE.23.019586.
de Vries, O., Saule, T., Plötner, M., Lücking, F., Eidam, T., Hoffmann, A., Klenke, A., Hädrich, S., Limpert, J., Holzberger, S., Schreiber, T., Eberhardt, R., Pupeza, I., & Tünnermann, A. (2015). Acousto-optic pulse picking scheme with carrier-frequency-to-pulse-repetition-rate synchronization. Optics express, 23(15), 19586-95. https://doi.org/10.1364/OE.23.019586
de Vries, Oliver, et al. "Acousto-optic pulse picking scheme with carrier-frequency-to-pulse-repetition-rate synchronization." Optics express vol. 23,15 (2015): 19586-95. doi: https://doi.org/10.1364/OE.23.019586
de Vries O, Saule T, Plötner M, Lücking F, Eidam T, Hoffmann A, Klenke A, Hädrich S, Limpert J, Holzberger S, Schreiber T, Eberhardt R, Pupeza I, Tünnermann A. Acousto-optic pulse picking scheme with carrier-frequency-to-pulse-repetition-rate synchronization. Opt Express. 2015 Jul 27;23(15):19586-95. doi: 10.1364/OE.23.019586. PMID: 26367616.
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Coulomb blockade based field-effect transistors exploiting stripe-shaped channel geometries of self-assembled metal nanoparticles.

Nanoscale

Lehmann H, Willing S, Möller S, Volkmann M, Klinke C.
PMID: 27232949
Nanoscale. 2016 Aug 14;8(30):14384-92. doi: 10.1039/c6nr02489k. Epub 2016 May 27.

Metallic nanoparticles offer possibilities to build basic electric devices with new functionality and improved performance. Due to the small volume and the resulting low self-capacitance, each single nanoparticle exhibits a high charging energy. Thus, a Coulomb-energy gap emerges during...

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Lehmann H, Willing S, Möller S, et al. Coulomb blockade based field-effect transistors exploiting stripe-shaped channel geometries of self-assembled metal nanoparticles. Nanoscale. 2016;8(30):14384-92doi: 10.1039/c6nr02489k.
Lehmann, H., Willing, S., Möller, S., Volkmann, M., & Klinke, C. (2016). Coulomb blockade based field-effect transistors exploiting stripe-shaped channel geometries of self-assembled metal nanoparticles. Nanoscale, 8(30), 14384-92. https://doi.org/10.1039/c6nr02489k
Lehmann, Hauke, et al. "Coulomb blockade based field-effect transistors exploiting stripe-shaped channel geometries of self-assembled metal nanoparticles." Nanoscale vol. 8,30 (2016): 14384-92. doi: https://doi.org/10.1039/c6nr02489k
Lehmann H, Willing S, Möller S, Volkmann M, Klinke C. Coulomb blockade based field-effect transistors exploiting stripe-shaped channel geometries of self-assembled metal nanoparticles. Nanoscale. 2016 Aug 14;8(30):14384-92. doi: 10.1039/c6nr02489k. Epub 2016 May 27. PMID: 27232949.
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Single-particle tracking uncovers dynamics of glutamate-induced retrograde transport of NF-κB p65 in living neurons.

Neurophotonics

Widera D, Klenke C, Nair D, Heidbreder M, Malkusch S, Sibarita JB, Choquet D, Kaltschmidt B, Heilemann M, Kaltschmidt C.
PMID: 27226975
Neurophotonics. 2016 Oct;3(4):041804. doi: 10.1117/1.NPh.3.4.041804. Epub 2016 May 18.

Retrograde transport of NF-κB from the synapse to the nucleus in neurons is mediated by the dynein/dynactin motor complex and can be triggered by synaptic activation. The caliber of axons is highly variable ranging down to 100 nm, aggravating...

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Widera D, Klenke C, Nair D, et al. Single-particle tracking uncovers dynamics of glutamate-induced retrograde transport of NF-κB p65 in living neurons. Neurophotonics. 2016;3(4):041804doi: 10.1117/1.NPh.3.4.041804.
Widera, D., Klenke, C., Nair, D., Heidbreder, M., Malkusch, S., Sibarita, J. B., Choquet, D., Kaltschmidt, B., Heilemann, M., & Kaltschmidt, C. (2016). Single-particle tracking uncovers dynamics of glutamate-induced retrograde transport of NF-κB p65 in living neurons. Neurophotonics, 3(4), 041804. https://doi.org/10.1117/1.NPh.3.4.041804
Widera, Darius, et al. "Single-particle tracking uncovers dynamics of glutamate-induced retrograde transport of NF-κB p65 in living neurons." Neurophotonics vol. 3,4 (2016): 041804. doi: https://doi.org/10.1117/1.NPh.3.4.041804
Widera D, Klenke C, Nair D, Heidbreder M, Malkusch S, Sibarita JB, Choquet D, Kaltschmidt B, Heilemann M, Kaltschmidt C. Single-particle tracking uncovers dynamics of glutamate-induced retrograde transport of NF-κB p65 in living neurons. Neurophotonics. 2016 Oct;3(4):041804. doi: 10.1117/1.NPh.3.4.041804. Epub 2016 May 18. PMID: 27226975; PMCID: PMC4870386.
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Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells.

Scientific reports

Vogel S, Grabski E, Buschjäger D, Klawonn F, Döring M, Wang J, Fletcher E, Bechmann I, Witte T, Durisin M, Schraven B, Mangsbo SM, Schönfeld K, Czeloth N, Kalinke U.
PMID: 26670584
Sci Rep. 2015 Dec 16;5:18308. doi: 10.1038/srep18308.

Treatment of PBMC with the CD4-specific mAb BT-061 induces CD4 down-modulation of T cells. Here we report that addition of BT-061 to purified T cells did not confer this effect, whereas incubation of T cells in BT-061 coated wells...

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Vogel S, Grabski E, Buschjäger D, et al. Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells. Sci Rep. 2015;5:18308doi: 10.1038/srep18308.
Vogel, S., Grabski, E., Buschjäger, D., Klawonn, F., Döring, M., Wang, J., Fletcher, E., Bechmann, I., Witte, T., Durisin, M., Schraven, B., Mangsbo, S. M., Schönfeld, K., Czeloth, N., & Kalinke, U. (2015). Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells. Scientific reports, 518308. https://doi.org/10.1038/srep18308
Vogel, Stephanie, et al. "Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells." Scientific reports vol. 5 (2015): 18308. doi: https://doi.org/10.1038/srep18308
Vogel S, Grabski E, Buschjäger D, Klawonn F, Döring M, Wang J, Fletcher E, Bechmann I, Witte T, Durisin M, Schraven B, Mangsbo SM, Schönfeld K, Czeloth N, Kalinke U. Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells. Sci Rep. 2015 Dec 16;5:18308. doi: 10.1038/srep18308. PMID: 26670584; PMCID: PMC4680940.
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Metal Domain Size Dependent Electrical Transport in Pt-CdSe Hybrid Nanoparticle Monolayers.

ACS nano

Meyns M, Willing S, Lehmann H, Klinke C.
PMID: 26052966
ACS Nano. 2015 Jun 23;9(6):6077-87. doi: 10.1021/acsnano.5b01221. Epub 2015 Jun 08.

Thin films prepared of semiconductor nanoparticles are promising for low-cost electronic applications such as transistors and solar cells. One hurdle for their breakthrough is their notoriously low conductivity. To address this, we precisely decorate CdSe nanoparticles with platinum domains...

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Meyns M, Willing S, Lehmann H, et al. Metal Domain Size Dependent Electrical Transport in Pt-CdSe Hybrid Nanoparticle Monolayers. ACS Nano. 2015;9(6):6077-87doi: 10.1021/acsnano.5b01221.
Meyns, M., Willing, S., Lehmann, H., & Klinke, C. (2015). Metal Domain Size Dependent Electrical Transport in Pt-CdSe Hybrid Nanoparticle Monolayers. ACS nano, 9(6), 6077-87. https://doi.org/10.1021/acsnano.5b01221
Meyns, Michaela, et al. "Metal Domain Size Dependent Electrical Transport in Pt-CdSe Hybrid Nanoparticle Monolayers." ACS nano vol. 9,6 (2015): 6077-87. doi: https://doi.org/10.1021/acsnano.5b01221
Meyns M, Willing S, Lehmann H, Klinke C. Metal Domain Size Dependent Electrical Transport in Pt-CdSe Hybrid Nanoparticle Monolayers. ACS Nano. 2015 Jun 23;9(6):6077-87. doi: 10.1021/acsnano.5b01221. Epub 2015 Jun 08. PMID: 26052966.
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Divided-pulse nonlinear compression.

Optics letters

Klenke A, Kienel M, Eidam T, Hädrich S, Limpert J, Tünnermann A.
PMID: 24322082
Opt Lett. 2013 Nov 15;38(22):4593-6. doi: 10.1364/OL.38.004593.

We report on the nonlinear pulse compression of temporally divided pulses, which is presented in a proof-of-principle experiment. A single 320 fs pulse is divided into four replicas, spectrally broadened in a solid-core fiber, and subsequently recombined. This approach...

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Klenke A, Kienel M, Eidam T, et al. Divided-pulse nonlinear compression. Opt Lett. 2013;38(22):4593-6doi: 10.1364/OL.38.004593.
Klenke, A., Kienel, M., Eidam, T., Hädrich, S., Limpert, J., & Tünnermann, A. (2013). Divided-pulse nonlinear compression. Optics letters, 38(22), 4593-6. https://doi.org/10.1364/OL.38.004593
Klenke, Arno, et al. "Divided-pulse nonlinear compression." Optics letters vol. 38,22 (2013): 4593-6. doi: https://doi.org/10.1364/OL.38.004593
Klenke A, Kienel M, Eidam T, Hädrich S, Limpert J, Tünnermann A. Divided-pulse nonlinear compression. Opt Lett. 2013 Nov 15;38(22):4593-6. doi: 10.1364/OL.38.004593. PMID: 24322082.
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Seasonal and urban effects on the endocrinology of a wild passerine.

Ecology and evolution

Russ A, Reitemeier S, Weissmann A, Gottschalk J, Einspanier A, Klenke R.
PMID: 27069618
Ecol Evol. 2015 Nov 19;5(23):5698-710. doi: 10.1002/ece3.1820. eCollection 2015 Dec.

In order to maximize their fitness, organisms in seasonal environments rely on external cues to optimally time their life-history stages. One of the most important zeitgeber to time reproduction is the photoperiod, but further environmental cues are assessed to...

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Russ A, Reitemeier S, Weissmann A, et al. Seasonal and urban effects on the endocrinology of a wild passerine. Ecol Evol. 2015;5(23):5698-710doi: 10.1002/ece3.1820.
Russ, A., Reitemeier, S., Weissmann, A., Gottschalk, J., Einspanier, A., & Klenke, R. (2015). Seasonal and urban effects on the endocrinology of a wild passerine. Ecology and evolution, 5(23), 5698-710. https://doi.org/10.1002/ece3.1820
Russ, Anja, et al. "Seasonal and urban effects on the endocrinology of a wild passerine." Ecology and evolution vol. 5,23 (2015): 5698-710. doi: https://doi.org/10.1002/ece3.1820
Russ A, Reitemeier S, Weissmann A, Gottschalk J, Einspanier A, Klenke R. Seasonal and urban effects on the endocrinology of a wild passerine. Ecol Evol. 2015 Nov 19;5(23):5698-710. doi: 10.1002/ece3.1820. eCollection 2015 Dec. PMID: 27069618; PMCID: PMC4813110.
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Mesenchymal stem cells in the treatment of inflammatory and autoimmune diseases in experimental animal models.

World journal of stem cells

Klinker MW, Wei CH.
PMID: 25914763
World J Stem Cells. 2015 Apr 26;7(3):556-67. doi: 10.4252/wjsc.v7.i3.556.

Multipotent mesenchymal stromal cells [also known as mesenchymal stem cells (MSCs)] are currently being studied as a cell-based treatment for inflammatory disorders. Experimental animal models of human immune-mediated diseases have been instrumental in establishing their immunosuppressive properties. In this...

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Klinker MW, Wei CH. Mesenchymal stem cells in the treatment of inflammatory and autoimmune diseases in experimental animal models. World J Stem Cells. 2015;7(3):556-67doi: 10.4252/wjsc.v7.i3.556.
Klinker, M. W., & Wei, C. H. (2015). Mesenchymal stem cells in the treatment of inflammatory and autoimmune diseases in experimental animal models. World journal of stem cells, 7(3), 556-67. https://doi.org/10.4252/wjsc.v7.i3.556
Klinker, Matthew W, and Wei, Cheng-Hong. "Mesenchymal stem cells in the treatment of inflammatory and autoimmune diseases in experimental animal models." World journal of stem cells vol. 7,3 (2015): 556-67. doi: https://doi.org/10.4252/wjsc.v7.i3.556
Klinker MW, Wei CH. Mesenchymal stem cells in the treatment of inflammatory and autoimmune diseases in experimental animal models. World J Stem Cells. 2015 Apr 26;7(3):556-67. doi: 10.4252/wjsc.v7.i3.556. PMID: 25914763; PMCID: PMC4404391.
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Immunoadsorption versus plasma exchange versus combination for treatment of myasthenic deterioration.

Therapeutic advances in neurological disorders

Schneider-Gold C, Krenzer M, Klinker E, Mansouri-Thalegani B, Müllges W, Toyka KV, Gold R.
PMID: 27366236
Ther Adv Neurol Disord. 2016 Jul;9(4):297-303. doi: 10.1177/1756285616637046. Epub 2016 Mar 10.

OBJECTIVES: The goal of this study was to analyze safety and assess the efficacy of standard plasma exchange (PE) compared with immunoadsorption (IA) alone, or an alternating combination of both in deteriorating myasthenia gravis (MG).METHODS: A total of 72...

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Schneider-Gold C, Krenzer M, Klinker E, et al. Immunoadsorption versus plasma exchange versus combination for treatment of myasthenic deterioration. Ther Adv Neurol Disord. 2016;9(4):297-303doi: 10.1177/1756285616637046.
Schneider-Gold, C., Krenzer, M., Klinker, E., Mansouri-Thalegani, B., Müllges, W., Toyka, K. V., & Gold, R. (2016). Immunoadsorption versus plasma exchange versus combination for treatment of myasthenic deterioration. Therapeutic advances in neurological disorders, 9(4), 297-303. https://doi.org/10.1177/1756285616637046
Schneider-Gold, Christiane, et al. "Immunoadsorption versus plasma exchange versus combination for treatment of myasthenic deterioration." Therapeutic advances in neurological disorders vol. 9,4 (2016): 297-303. doi: https://doi.org/10.1177/1756285616637046
Schneider-Gold C, Krenzer M, Klinker E, Mansouri-Thalegani B, Müllges W, Toyka KV, Gold R. Immunoadsorption versus plasma exchange versus combination for treatment of myasthenic deterioration. Ther Adv Neurol Disord. 2016 Jul;9(4):297-303. doi: 10.1177/1756285616637046. Epub 2016 Mar 10. PMID: 27366236; PMCID: PMC4916519.
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Showing 1 to 12 of 308 entries