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Age-dependent sex differences in calcium and phosphate homeostasis.

Endocrine connections

Koek WNH, Campos-Obando N, van der Eerden BCJ, de Rijke YB, Ikram MA, Uitterlinden AG, van Leeuwen JPTM, Zillikens MC.
PMID: 33543729
Endocr Connect. 2021 Mar;10(3):273-282. doi: 10.1530/EC-20-0509.

BACKGROUND: Sex differences in calcium and phosphate have been observed. We aimed to assess a relation with age.METHODS: We used the laboratory values of serum calcium, phosphate and albumin from three different samples ( 2005, 2010 and 2014 years)...

Serum and cerebrospinal fluid Neutrophil gelatinase-associated lipocalin (NGAL) levels as biomarkers for the conversion from mild cognitive impairment to Alzheimer's disease dementia.

Neurobiology of aging

Naudé PJW, Ramakers IHGB, van der Flier WM, Jiskoot LC, Reesink FE, Claassen JAHR, Koek HL, Eisel ULM, De Deyn PP.
PMID: 34365256
Neurobiol Aging. 2021 Nov;107:1-10. doi: 10.1016/j.neurobiolaging.2021.07.001. Epub 2021 Jul 10.

Neutrophil gelatinase-associated lipocalin (NGAL) is an acute phase protein that has been reported as a potential marker for pre-dementia stages of Alzheimer's disease (AD). Longitudinal studies for its association with the conversion of mild cognitive impairment to AD is...

Heterogeneity of glutamine metabolism in acquired-EGFR-TKI-resistant lung cancer.

Life sciences

Kim S, Jeon JS, Choi YJ, Baek GH, Kim SK, Kang KW.
PMID: 34990648
Life Sci. 2022 Jan 03;120274. doi: 10.1016/j.lfs.2021.120274. Epub 2022 Jan 03.

AIMS: The purpose of this study was to evaluate the heterogeneities of glutamine metabolism in EGFR-TKI-resistant lung cancer cells and its potential as a therapeutic target.MAIN METHODS: Cell proliferation and cell cycle assays was performed by IncuCyte real-time analysis...

Improving Understanding and Outcomes in Congenital Hand Differences.

Plastic and reconstructive surgery

Baek GH, Kim J.
PMID: 34705781
Plast Reconstr Surg. 2021 Nov 01;148(5):769e-774e. doi: 10.1097/PRS.0000000000008413.

SUMMARY: It is very important for us, the surgeons, to understand the difficulties of parents who have a baby with a congenital hand difference, not only because the parents are the decision makers for the operation but also because...

Effects of the NMDA antagonist, dizocilpine, in various drug discriminations: characterization of intermediate levels of drug lever selection.

Behavioural pharmacology

Koek W, Kleven MS, Colpaert FC.
PMID: 11224366
Behav Pharmacol. 1995 Aug;6(5):590-600.

In each of different groups of rats trained to discriminate either 8-OH-DPAT, DOI, d-amphetamine, cocaine, chlordiazepoide or ethanol from saline, dizocilpine produced maximum percentages of drug lever (DL) selection that were intermediate between those produced by the training conditions....

Sports related fractures: A review of 113 cases.

Journal of orthopaedic surgery (Hong Kong)

Hon WH, Kock SH.
PMID: 12468841
J Orthop Surg (Hong Kong). 2001 Jun;9(1):35-38. doi: 10.1177/230949900100900107.

To establish a profile of fractures related to sporting activities, to determine the extent to which these injuries resulted in morbidity, and to find suitable target areas for injury prevention, a one-year study was undertaken at Seremban Hospital, Negeri...

Holographic simultaneous readout polarization multiplexing based on photoinduced anisotropy in bacteriorhodopsin.

Optics letters

Koek WD, Bhattacharya N, Braat JJ, Chan VS, Westerweel J.
PMID: 14719674
Opt Lett. 2004 Jan 01;29(1):101-3. doi: 10.1364/ol.29.000101.

Bacteriorhodopsin (bR) is a reversible photochromic protein that can be used as a holographic medium. The dichroic absorption of the bR molecule is polarization dependent, thereby allowing for the recording of polarization holograms. The properties of polarization holograms can...

Coronaviral RNA-methyltransferases: function, structure and inhibition.

Nucleic acids research

Nencka R, Silhan J, Klima M, Otava T, Kocek H, Krafcikova P, Boura E.
PMID: 35018474
Nucleic Acids Res. 2022 Jan 08; doi: 10.1093/nar/gkab1279. Epub 2022 Jan 08.

Coronaviral methyltransferases (MTases), nsp10/16 and nsp14, catalyze the last two steps of viral RNA-cap creation that takes place in cytoplasm. This cap is essential for the stability of viral RNA and, most importantly, for the evasion of innate immune...

Cdc48: a swiss army knife of cell biology.

Journal of amino acids

Baek GH, Cheng H, Choe V, Bao X, Shao J, Luo S, Rao H.
PMID: 24167726
J Amino Acids. 2013;2013:183421. doi: 10.1155/2013/183421. Epub 2013 Sep 15.

Cdc48 (also called VCP and p97) is an abundant protein that plays essential regulatory functions in a broad array of cellular processes. Working with various cofactors, Cdc48 utilizes its ATPase activity to promote the assembly and disassembly of protein...

Cutaneous mucormycosis in an immunocompromised patient: a case report.

Journal of surgical case reports

Suthananthan AE, Koek SA, Sieunarine K.
PMID: 28458862
J Surg Case Rep. 2017 Mar 14;2017(3):rjx056. doi: 10.1093/jscr/rjx056. eCollection 2017 Mar.

Mucormycosis is a rare and highly aggressive fungal infection, with a potential to reach its fulminant phase rapidly. We report a case of a 73-year-old immunocompromised vasculopath with cutaneous mucormycosis. The disease resulted in eventual death despite aggressive surgical...

Vascular Cognitive Impairment in a Memory Clinic Population: Rationale and Design of the "Utrecht-Amsterdam Clinical Features and Prognosis in Vascular Cognitive Impairment" (TRACE-VCI) Study.

JMIR research protocols

Boomsma JMF, Exalto LG, Barkhof F, van den Berg E, de Bresser J, Heinen R, Koek HL, Prins ND, Scheltens P, Weinstein HC, van der Flier WM, Biessels GJ.
PMID: 28428166
JMIR Res Protoc. 2017 Apr 19;6(4):e60. doi: 10.2196/resprot.6864.

BACKGROUND: Vascular Cognitive Impairment (VCI) refers to cognitive dysfunction due to vascular brain injury, as a single cause or in combination with other, often neurodegenerative, etiologies. VCI is a broad construct that captures a heterogeneous patient population both in...

Animal-habitat relationships in the Knysna Forest, South Africa: discrimination between forest types by birds and invertebrates.


Koen JH, Crowe TM.
PMID: 28311139
Oecologia. 1987 Jun;72(3):414-422. doi: 10.1007/BF00377573.

Effects of forest plant species composition and physiognomy on bird and invertebrate communities were investigated in three discrete, relatively undisturbed forest types along a dry-wet soil moisture gradient. Using discriminant function analysis, a 100% floristic and a 78% vegetation...

Showing 1 to 12 of 152 entries