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Hypoxia-induced pulmonary hypertension and chronic lung disease: caveolin-1 dysfunction an important underlying feature.

Pulmonary circulation

Huang J, Frid M, Gewitz MH, Fallon JT, Brown D, Krafsur G, Stenmark K, Mathew R.
PMID: 30806156
Pulm Circ. 2019 Jan-Mar;9(1):2045894019837876. doi: 10.1177/2045894019837876.

Caveolin-1 (cav-1) has been shown to play a significant role in the pathogenesis of pulmonary hypertension (PH). In the monocrotaline model of PH, the loss of endothelial cav-1 as well as reciprocal activation of proliferative and anti-apoptotic pathways initiate...

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Huang J, Frid M, Gewitz MH, et al. Hypoxia-induced pulmonary hypertension and chronic lung disease: caveolin-1 dysfunction an important underlying feature. Pulm Circ. 2019;9(1):2045894019837876doi: 10.1177/2045894019837876.
Huang, J., Frid, M., Gewitz, M. H., Fallon, J. T., Brown, D., Krafsur, G., Stenmark, K., & Mathew, R. (2019). Hypoxia-induced pulmonary hypertension and chronic lung disease: caveolin-1 dysfunction an important underlying feature. Pulmonary circulation, 9(1), 2045894019837876. https://doi.org/10.1177/2045894019837876
Huang, Jing, et al. "Hypoxia-induced pulmonary hypertension and chronic lung disease: caveolin-1 dysfunction an important underlying feature." Pulmonary circulation vol. 9,1 (2019): 2045894019837876. doi: https://doi.org/10.1177/2045894019837876
Huang J, Frid M, Gewitz MH, Fallon JT, Brown D, Krafsur G, Stenmark K, Mathew R. Hypoxia-induced pulmonary hypertension and chronic lung disease: caveolin-1 dysfunction an important underlying feature. Pulm Circ. 2019 Jan-Mar;9(1):2045894019837876. doi: 10.1177/2045894019837876. PMID: 30806156; PMCID: PMC6434444.
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Brief Report: Case Comparison of Therapy With the Histone Deacetylase Inhibitor Vorinostat in a Neonatal Calf Model of Pulmonary Hypertension.

Frontiers in physiology

Applegate TJ, Krafsur GM, Boon JA, Zhang H, Li M, Holt TN, Ambler SK, Abrams BA, Gustafson DL, Bartels K, Garry FB, Stenmark KR, Brown RD.
PMID: 34552503
Front Physiol. 2021 Sep 06;12:712583. doi: 10.3389/fphys.2021.712583. eCollection 2021.

Pulmonary hypertension (PH) is an incurable condition in humans; driven by pulmonary vascular remodeling partially mediated by epigenetic mechanisms; and leading to right ventricular hypertrophy, failure, and death. We hypothesized that targeting chromatin-modifying histone deacetylases may provide benefit. In...

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Applegate TJ, Krafsur GM, Boon JA, et al. Brief Report: Case Comparison of Therapy With the Histone Deacetylase Inhibitor Vorinostat in a Neonatal Calf Model of Pulmonary Hypertension. Front Physiol. 2021;12:712583doi: 10.3389/fphys.2021.712583.
Applegate, T. J., Krafsur, G. M., Boon, J. A., Zhang, H., Li, M., Holt, T. N., Ambler, S. K., Abrams, B. A., Gustafson, D. L., Bartels, K., Garry, F. B., Stenmark, K. R., & Brown, R. D. (2021). Brief Report: Case Comparison of Therapy With the Histone Deacetylase Inhibitor Vorinostat in a Neonatal Calf Model of Pulmonary Hypertension. Frontiers in physiology, 12712583. https://doi.org/10.3389/fphys.2021.712583
Applegate, Tanya J, et al. "Brief Report: Case Comparison of Therapy With the Histone Deacetylase Inhibitor Vorinostat in a Neonatal Calf Model of Pulmonary Hypertension." Frontiers in physiology vol. 12 (2021): 712583. doi: https://doi.org/10.3389/fphys.2021.712583
Applegate TJ, Krafsur GM, Boon JA, Zhang H, Li M, Holt TN, Ambler SK, Abrams BA, Gustafson DL, Bartels K, Garry FB, Stenmark KR, Brown RD. Brief Report: Case Comparison of Therapy With the Histone Deacetylase Inhibitor Vorinostat in a Neonatal Calf Model of Pulmonary Hypertension. Front Physiol. 2021 Sep 06;12:712583. doi: 10.3389/fphys.2021.712583. eCollection 2021. PMID: 34552503; PMCID: PMC8450341.
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Circulating MicroRNA Markers for Pulmonary Hypertension in Supervised Exercise Intervention and Nightly Oxygen Intervention.

Frontiers in physiology

Grunig G, Eichstaedt CA, Verweyen J, Durmus N, Saxer S, Krafsur G, Stenmark K, Ulrich S, Grünig E, Pylawka S.
PMID: 30090067
Front Physiol. 2018 Jul 25;9:955. doi: 10.3389/fphys.2018.00955. eCollection 2018.

No abstract available.

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Grunig G, Eichstaedt CA, Verweyen J, et al. Circulating MicroRNA Markers for Pulmonary Hypertension in Supervised Exercise Intervention and Nightly Oxygen Intervention. Front Physiol. 2018;9:955doi: 10.3389/fphys.2018.00955.
Grunig, G., Eichstaedt, C. A., Verweyen, J., Durmus, N., Saxer, S., Krafsur, G., Stenmark, K., Ulrich, S., Grünig, E., & Pylawka, S. (2018). Circulating MicroRNA Markers for Pulmonary Hypertension in Supervised Exercise Intervention and Nightly Oxygen Intervention. Frontiers in physiology, 9955. https://doi.org/10.3389/fphys.2018.00955
Grunig, Gabriele, et al. "Circulating MicroRNA Markers for Pulmonary Hypertension in Supervised Exercise Intervention and Nightly Oxygen Intervention." Frontiers in physiology vol. 9 (2018): 955. doi: https://doi.org/10.3389/fphys.2018.00955
Grunig G, Eichstaedt CA, Verweyen J, Durmus N, Saxer S, Krafsur G, Stenmark K, Ulrich S, Grünig E, Pylawka S. Circulating MicroRNA Markers for Pulmonary Hypertension in Supervised Exercise Intervention and Nightly Oxygen Intervention. Front Physiol. 2018 Jul 25;9:955. doi: 10.3389/fphys.2018.00955. eCollection 2018. PMID: 30090067; PMCID: PMC6068281.
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Identification and properties of microsatellite markers in tsetse flies Glossina morsitans sensu lato (Diptera: Glossinidae).

Molecular ecology notes

Baker MD, Krafsur ES.
PMID: 16479272
Mol Ecol Notes. 2001 Dec;1(4):234-236. doi: 10.1046/j.1471-8278.2001.00087.x.

Genomic libraries enriched for simple sequence repeats were constructed for Glossina morsitans morsitans, G. m. submorsitans, and G. m. centralis. Sixteen microsatellite markers were isolated from the libraries and evaluated on flies from natural G. m. morsitans populations and...

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Baker MD, Krafsur ES. Identification and properties of microsatellite markers in tsetse flies Glossina morsitans sensu lato (Diptera: Glossinidae). Mol Ecol Notes. 2001;1(4):234-236doi: 10.1046/j.1471-8278.2001.00087.x.
Baker, M. D., & Krafsur, E. S. (2001). Identification and properties of microsatellite markers in tsetse flies Glossina morsitans sensu lato (Diptera: Glossinidae). Molecular ecology notes, 1(4), 234-236. https://doi.org/10.1046/j.1471-8278.2001.00087.x
Baker, M D, and Krafsur, E S. "Identification and properties of microsatellite markers in tsetse flies Glossina morsitans sensu lato (Diptera: Glossinidae)." Molecular ecology notes vol. 1,4 (2001): 234-236. doi: https://doi.org/10.1046/j.1471-8278.2001.00087.x
Baker MD, Krafsur ES. Identification and properties of microsatellite markers in tsetse flies Glossina morsitans sensu lato (Diptera: Glossinidae). Mol Ecol Notes. 2001 Dec;1(4):234-236. doi: 10.1046/j.1471-8278.2001.00087.x. PMID: 16479272; PMCID: PMC1364499.
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Gene flow in the exotic 14-spotted ladybird beetle, Propylea quatuordecimpunctata.

Genome

Krafsur ES, Obrycki JJ.
PMID: 18469882
Genome. 1996 Feb;39(1):131-9. doi: 10.1139/g96-018.

Propylea quatuordecimpunctata is a Palearctic ladybird beetle that has recently become established fortuitously in northeastern North America. This predator has also been cultured by the United States Department of Agriculture from geographically diverse Old World populations and propagated for...

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Krafsur ES, Obrycki JJ. Gene flow in the exotic 14-spotted ladybird beetle, Propylea quatuordecimpunctata. Genome. 1996;39(1):131-9doi: 10.1139/g96-018.
Krafsur, E. S., & Obrycki, J. J. (1996). Gene flow in the exotic 14-spotted ladybird beetle, Propylea quatuordecimpunctata. Genome, 39(1), 131-9. https://doi.org/10.1139/g96-018
Krafsur, E S, and Obrycki, J J. "Gene flow in the exotic 14-spotted ladybird beetle, Propylea quatuordecimpunctata." Genome vol. 39,1 (1996): 131-9. doi: https://doi.org/10.1139/g96-018
Krafsur ES, Obrycki JJ. Gene flow in the exotic 14-spotted ladybird beetle, Propylea quatuordecimpunctata. Genome. 1996 Feb;39(1):131-9. doi: 10.1139/g96-018. PMID: 18469882.
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Genetic diversity and gene flow in morsitans group tsetse flies.

Tsetse and trypanosomiasis information quarterly

Krafsur ES.
PMID: 19936274
Tsetse Trypanos Inf Q. 2002;25:141-146.

No abstract available.

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Krafsur ES. Genetic diversity and gene flow in morsitans group tsetse flies. Tsetse Trypanos Inf Q. 2002;25:141-146
Krafsur, E. S. (2002). Genetic diversity and gene flow in morsitans group tsetse flies. Tsetse and trypanosomiasis information quarterly, 25141-146.
Krafsur, E S. "Genetic diversity and gene flow in morsitans group tsetse flies." Tsetse and trypanosomiasis information quarterly vol. 25 (2002): 141-146.
Krafsur ES. Genetic diversity and gene flow in morsitans group tsetse flies. Tsetse Trypanos Inf Q. 2002;25:141-146. PMID: 19936274; PMCID: PMC2779772.
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A FORTRAN program for analysis of genotypic frequencies and description of the breeding structure of populations.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

Black WC, Krafsur ES.
PMID: 24253057
Theor Appl Genet. 1985 Aug;70(5):484-90. doi: 10.1007/BF00305980.

A FORTRAN program, "Genestats" was designed to analyse genotypic and allelic frequencies in subpopulations. The genotypes of individuals gathered from electrophoretic analysis at one or more loci are submitted. The program subsequently calculates allele frequencies, determines if significant heterogeneity...

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Black WC, Krafsur ES. A FORTRAN program for analysis of genotypic frequencies and description of the breeding structure of populations. Theor Appl Genet. 1985;70(5):484-90doi: 10.1007/BF00305980.
Black, W. C., & Krafsur, E. S. (1985). A FORTRAN program for analysis of genotypic frequencies and description of the breeding structure of populations. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 70(5), 484-90. https://doi.org/10.1007/BF00305980
Black, W C, and Krafsur, E S. "A FORTRAN program for analysis of genotypic frequencies and description of the breeding structure of populations." TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik vol. 70,5 (1985): 484-90. doi: https://doi.org/10.1007/BF00305980
Black WC, Krafsur ES. A FORTRAN program for analysis of genotypic frequencies and description of the breeding structure of populations. Theor Appl Genet. 1985 Aug;70(5):484-90. doi: 10.1007/BF00305980. PMID: 24253057.
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A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

Black WC, Krafsur ES.
PMID: 24253058
Theor Appl Genet. 1985 Aug;70(5):491-6. doi: 10.1007/BF00305981.

A FORTRAN program was written that calculates composite linkage disequilibrium coefficients from genotypic data. Chi-square tests determine whether coefficients calculated for allele and locus pairs are significantly greater than zero. A subroutine is provided that partitions the variance in...

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Black WC, Krafsur ES. A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients. Theor Appl Genet. 1985;70(5):491-6doi: 10.1007/BF00305981.
Black, W. C., & Krafsur, E. S. (1985). A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 70(5), 491-6. https://doi.org/10.1007/BF00305981
Black, W C, and Krafsur, E S. "A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients." TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik vol. 70,5 (1985): 491-6. doi: https://doi.org/10.1007/BF00305981
Black WC, Krafsur ES. A FORTRAN program for the calculation and analysis of two-locus linkage disequilibrium coefficients. Theor Appl Genet. 1985 Aug;70(5):491-6. doi: 10.1007/BF00305981. PMID: 24253058.
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Phenotypic Response of .

Microorganisms

Krafsur AM, Ghosh A, Brelsfoard CL.
PMID: 32708688
Microorganisms. 2020 Jul 16;8(7). doi: 10.3390/microorganisms8071060.

No abstract available.

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Krafsur AM, Ghosh A, Brelsfoard CL. Phenotypic Response of . Microorganisms. 2020;8(7)doi: 10.3390/microorganisms8071060.
Krafsur, A. M., Ghosh, A., & Brelsfoard, C. L. (2020). Phenotypic Response of . Microorganisms, 8(7), . https://doi.org/10.3390/microorganisms8071060
Krafsur, Alyssa M, et al. "Phenotypic Response of ." Microorganisms vol. 8,7 (2020). doi: https://doi.org/10.3390/microorganisms8071060
Krafsur AM, Ghosh A, Brelsfoard CL. Phenotypic Response of . Microorganisms. 2020 Jul 16;8(7). doi: 10.3390/microorganisms8071060. PMID: 32708688; PMCID: PMC7409048.
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Temporal and spatial trends in allozyme frequencies in house fly populations, Musca domestica L.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik

Black WC, Krafsur ES.
PMID: 24247601
Theor Appl Genet. 1986 Feb;71(5):673-81. doi: 10.1007/BF00263263.

Allelic and genotypic frequencies were sampled from a single age class of the common house fly, Musca domestica L., at five farms on six dates from July 6 to October 12, 1982. Allozymes at six loci were resolved with...

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Black WC, Krafsur ES. Temporal and spatial trends in allozyme frequencies in house fly populations, Musca domestica L. Theor Appl Genet. 1986;71(5):673-81doi: 10.1007/BF00263263.
Black, W. C., & Krafsur, E. S. (1986). Temporal and spatial trends in allozyme frequencies in house fly populations, Musca domestica L. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 71(5), 673-81. https://doi.org/10.1007/BF00263263
Black, W C, and Krafsur, E S. "Temporal and spatial trends in allozyme frequencies in house fly populations, Musca domestica L." TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik vol. 71,5 (1986): 673-81. doi: https://doi.org/10.1007/BF00263263
Black WC, Krafsur ES. Temporal and spatial trends in allozyme frequencies in house fly populations, Musca domestica L. Theor Appl Genet. 1986 Feb;71(5):673-81. doi: 10.1007/BF00263263. PMID: 24247601.
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GEOGRAPHIC VARIATION IN HOUSE FLY SIZE: ADAPTATION OR LARVAL CROWDING?.

Evolution; international journal of organic evolution

Black WC, Krafsur ES.
PMID: 28564109
Evolution. 1986 Jan;40(1):204-206. doi: 10.1111/j.1558-5646.1986.tb05732.x.

No abstract available.

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Black WC, Krafsur ES. GEOGRAPHIC VARIATION IN HOUSE FLY SIZE: ADAPTATION OR LARVAL CROWDING?. Evolution. 1986;40(1):204-206doi: 10.1111/j.1558-5646.1986.tb05732.x.
Black, W. C., & Krafsur, E. S. (1986). GEOGRAPHIC VARIATION IN HOUSE FLY SIZE: ADAPTATION OR LARVAL CROWDING?. Evolution; international journal of organic evolution, 40(1), 204-206. https://doi.org/10.1111/j.1558-5646.1986.tb05732.x
Black, W C, and Krafsur, E S. "GEOGRAPHIC VARIATION IN HOUSE FLY SIZE: ADAPTATION OR LARVAL CROWDING?." Evolution; international journal of organic evolution vol. 40,1 (1986): 204-206. doi: https://doi.org/10.1111/j.1558-5646.1986.tb05732.x
Black WC, Krafsur ES. GEOGRAPHIC VARIATION IN HOUSE FLY SIZE: ADAPTATION OR LARVAL CROWDING?. Evolution. 1986 Jan;40(1):204-206. doi: 10.1111/j.1558-5646.1986.tb05732.x. PMID: 28564109.
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Cardiopulmonary remodeling in fattened beef cattle: a naturally occurring large animal model of obesity-associated pulmonary hypertension with left heart disease.

Pulmonary circulation

Krafsur GM, Neary JM, Garry F, Holt T, Gould DH, Mason GL, Thomas MG, Enns RM, Tuder RM, Heaton MP, Brown RD, Stenmark KR.
PMID: 30124135
Pulm Circ. 2019 Jan-Mar;9(1):2045894018796804. doi: 10.1177/2045894018796804. Epub 2018 Aug 20.

The obesity epidemic in developed societies has led to increased cardiovascular diseases including pulmonary hypertension associated with left heart disease (PH-LHD), the largest and fastest-growing class of PH. Similar to obese humans, PH and heart failure (HF) are increasingly...

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Krafsur GM, Neary JM, Garry F, et al. Cardiopulmonary remodeling in fattened beef cattle: a naturally occurring large animal model of obesity-associated pulmonary hypertension with left heart disease. Pulm Circ. 2018;9(1):2045894018796804doi: 10.1177/2045894018796804.
Krafsur, G. M., Neary, J. M., Garry, F., Holt, T., Gould, D. H., Mason, G. L., Thomas, M. G., Enns, R. M., Tuder, R. M., Heaton, M. P., Brown, R. D., & Stenmark, K. R. (2019). Cardiopulmonary remodeling in fattened beef cattle: a naturally occurring large animal model of obesity-associated pulmonary hypertension with left heart disease. Pulmonary circulation, 9(1), 2045894018796804. https://doi.org/10.1177/2045894018796804
Krafsur, Greta M, et al. "Cardiopulmonary remodeling in fattened beef cattle: a naturally occurring large animal model of obesity-associated pulmonary hypertension with left heart disease." Pulmonary circulation vol. 9,1 (2019): 2045894018796804. doi: https://doi.org/10.1177/2045894018796804
Krafsur GM, Neary JM, Garry F, Holt T, Gould DH, Mason GL, Thomas MG, Enns RM, Tuder RM, Heaton MP, Brown RD, Stenmark KR. Cardiopulmonary remodeling in fattened beef cattle: a naturally occurring large animal model of obesity-associated pulmonary hypertension with left heart disease. Pulm Circ. 2019 Jan-Mar;9(1):2045894018796804. doi: 10.1177/2045894018796804. Epub 2018 Aug 20. PMID: 30124135; PMCID: PMC6333945.
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Showing 1 to 12 of 16 entries