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Showing 1 to 12 of 611 entries
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Broadening the PhD pipeline: A summer research program for HBCU students

HBCU broadening

Adida CL, Lake DA, Platt M.
GSID: hChDOuuqaQAJ
CL Adida, DA Lake, F Shafiei, M Platt - PS: Political Science & Politics, 2020 - cambridge.org

… This article describes one attempt to broaden the political … undergraduate students from two HBCUs to a summer research … This article outlines a possible model for broadening the …

Cadmium alters the formation of benzo[a]pyrene DNA adducts in the RPTEC/TERT1 human renal proximal tubule epithelial cell line.

Toxicology reports

Simon BR, Wilson MJ, Blake DA, Yu H, Wickliffe JK.
PMID: 25170436
Toxicol Rep. 2014 Jul 14;1:391-400. doi: 10.1016/j.toxrep.2014.07.003.

Previously, we demonstrated the sensitivity of RPTEC/TERT1 cells, an immortalized human renal proximal tubule epithelial cell line, to two common environmental carcinogens, cadmium (Cd) and benzo[a]pyrene (B[a]P). Here, we measured BPDE-DNA adducts using a competitive ELISA method after cells...

The town hall model in dermatology.

Medical education

Lake E, Tsoukas M.
PMID: 28394047
Med Educ. 2017 May;51(5):545-546. doi: 10.1111/medu.13319.

No abstract available.

Genetic signatures of ecological diversity along an urbanization gradient.

PeerJ

Kelly RP, O'Donnell JL, Lowell NC, Shelton AO, Samhouri JF, Hennessey SM, Feist BE, Williams GD.
PMID: 27672503
PeerJ. 2016 Sep 13;4:e2444. doi: 10.7717/peerj.2444. eCollection 2016.

Despite decades of work in environmental science and ecology, estimating human influences on ecosystems remains challenging. This is partly due to complex chains of causation among ecosystem elements, exacerbated by the difficulty of collecting biological data at sufficient spatial,...

Triptolide and its prodrug minnelide suppress Hsp70 and inhibit in vivo growth in a xenograft model of mesothelioma.

Genes & cancer

Jacobson BA, Chen EZ, Tang S, Belgum HS, McCauley JA, Evenson KA, Etchison RG, Jay-Dixon J, Patel MR, Raza A, Saluja AK, D'Cunha J, Kratzke RA.
PMID: 26000097
Genes Cancer. 2015 Mar;6(3):144-52. doi: 10.18632/genesandcancer.55.

Malignant mesothelioma is a devastating disease with a poor prognosis for which there is a clear need for more successful therapeutic approaches. Triptolide, a diterpenoid triepoxide, is a highly effective agent against several cancer types in animal models. Owing...

Janus Face Aspect of All-cis 1,2,3,4,5,6-Hexafluorocyclohexane Dictates Remarkable Anion and Cation Interactions In the Gas Phase.

Journal of the American Chemical Society

Ziegler BE, Lecours M, Marta RA, Featherstone J, Fillion E, Hopkins WS, Steinmetz V, Keddie NS, O'Hagan D, McMahon TB.
PMID: 27149387
J Am Chem Soc. 2016 Jun 22;138(24):7460-3. doi: 10.1021/jacs.6b02856. Epub 2016 May 12.

Experiments have been carried out in which electrospray ionization has been used to generate ionic complexes of all-cis 1,2,3,4,5,6 hexafluorocyclohexane. These complexes were subsequently mass isolated in a quadrupole ion trap mass spectrometer and then irradiated by the tunable...

Preservation of microbial communities enriched on lignocellulose under thermophilic and high-solid conditions.

Biotechnology for biofuels

Yu C, Reddy AP, Simmons CW, Simmons BA, Singer SW, VanderGheynst JS.
PMID: 26633993
Biotechnol Biofuels. 2015 Dec 02;8:206. doi: 10.1186/s13068-015-0392-y. eCollection 2015.

BACKGROUND: Microbial communities enriched from diverse environments have shown considerable promise for the targeted discovery of microorganisms and enzymes for bioconversion of lignocellulose to liquid fuels. While preservation of microbial communities is important for commercialization and research, few studies...

Discovery of the interstellar chiral molecule propylene oxide (CH₃CHCH₂O).

Science (New York, N.Y.)

McGuire BA, Carroll PB, Loomis RA, Finneran IA, Jewell PR, Remijan AJ, Blake GA.
PMID: 27303055
Science. 2016 Jun 17;352(6292):1449-52. doi: 10.1126/science.aae0328. Epub 2016 Jun 14.

Life on Earth relies on chiral molecules-that is, species not superimposable on their mirror images. This manifests itself in the selection of a single molecular handedness, or homochirality, across the biosphere. We present the astronomical detection of a chiral...

Ternary ionic liquid-water pretreatment systems of an agave bagasse and municipal solid waste blend.

Biotechnology for biofuels

Perez-Pimienta JA, Sathitsuksanoh N, Thompson VS, Tran K, Ponce-Noyola T, Stavila V, Singh S, Simmons BA.
PMID: 28344647
Biotechnol Biofuels. 2017 Mar 21;10:72. doi: 10.1186/s13068-017-0758-4. eCollection 2017.

BACKGROUND: Pretreatment is necessary to reduce biomass recalcitrance and enhance the efficiency of enzymatic saccharification for biofuel production. Ionic liquid (IL) pretreatment has gained a significant interest as a pretreatment process that can reduce cellulose crystallinity and remove lignin,...

Strong spontaneous tumor neoantigen responses induced by a natural human carcinogen.

Oncoimmunology

Creaney J, Ma S, Sneddon SA, Tourigny MR, Dick IM, Leon JS, Khong A, Fisher SA, Lake RA, Lesterhuis WJ, Nowak AK, Leary S, Watson MW, Robinson BW.
PMID: 26140232
Oncoimmunology. 2015 May 11;4(7):e1011492. doi: 10.1080/2162402X.2015.1011492. eCollection 2015 Jul.

A key to improving cancer immunotherapy will be the identification of tumor-specific "neoantigens" that arise from mutations and augment the resultant host immune response. In this study we identified single nucleotide variants (SNVs) by RNA sequencing of asbestos-induced murine...

Review of Therapeutic Interventions for the Upper Limb Classified by Manual Ability in Children with Cerebral Palsy.

Seminars in plastic surgery

Shierk A, Lake A, Haas T.
PMID: 26869859
Semin Plast Surg. 2016 Feb;30(1):14-23. doi: 10.1055/s-0035-1571256.

The aim of this literature review was to assemble an inventory of intervention strategies utilized for children diagnosed with cerebral palsy (CP) based on the Manual Ability Classification System (MACS). The purpose of the inventory is to guide physicians...

An overview of selected current approaches to the characterization of aqueous inorganic clusters.

Dalton transactions (Cambridge, England : 2003)

Jackson MN, Kamunde-Devonish MK, Hammann BA, Wills LA, Fullmer LB, Hayes SE, Cheong PH, Casey WH, Nyman M, Johnson DW.
PMID: 26212049
Dalton Trans. 2015 Oct 21;44(39):16982-7006. doi: 10.1039/c5dt01268f. Epub 2015 Jul 27.

This Perspective article highlights some of the traditional and non-traditional analytical tools that are presently used to characterize aqueous inorganic nanoscale clusters and polyoxometalate ions. The techniques discussed in this article include nuclear magnetic resonance spectroscopy (NMR), small angle...

Showing 1 to 12 of 611 entries