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Showing 1 to 12 of 152 entries
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A closer look into the nitrogen blank in elemental analyser/isotope ratio mass spectrometry measurements.

Rapid communications in mass spectrometry : RCM

Langel R, Dyckmans J.
PMID: 28940593
Rapid Commun Mass Spectrom. 2017 Dec 15;31(23):2051-2055. doi: 10.1002/rcm.7999.

RATIONALE: One important limitation for the precise measurement of minute amounts of nitrogen (N) in solid samples by elemental analyser/isotope ratio mass spectrometry (EA/IRMS) is the accurate determination of the analyser blank value. This study was performed to identify...

Hybrid Li Ion Conducting Membrane as Protection for the Li Anode in an Aqueous Li-Air Battery: Coupling Sol-Gel Chemistry and Electrospinning.

Langmuir : the ACS journal of surfaces and colloids

Lancel G, Stevens P, Toussaint G, Maréchal M, Krins N, Bregiroux D, Laberty-Robert C.
PMID: 28482152
Langmuir. 2017 Sep 19;33(37):9288-9297. doi: 10.1021/acs.langmuir.7b00675. Epub 2017 May 17.

Aqueous lithium-air batteries have very high theoretical energy densities, which potentially makes this technology very interesting for energy storage in electric mobility applications. However, the aqueous electrolyte requires the use of a watertight layer to protect the lithium metal,...

'Super committee' looks to health for savings to reduce deficits.

Health affairs (Project Hope)

Langel S.
PMID: 21976321
Health Aff (Millwood). 2011 Oct;30(10):1819-21. doi: 10.1377/hlthaff.2011.1057.

But, as with health care reform, Democrats and Republicans face off across a wide philosophical gulf.

Intracellular Delivery of Short Interfering RNA in Rat Organ of Corti Using a Cell-penetrating Peptide PepFect6.

Molecular therapy. Nucleic acids

Dash-Wagh S, Jacob S, Lindberg S, Fridberger A, Langel U, Ulfendahl M.
PMID: 23232329
Mol Ther Nucleic Acids. 2012 Dec 11;1:e61. doi: 10.1038/mtna.2012.50.

RNA interference (RNAi) using short interfering RNA (siRNA) is an attractive therapeutic approach for treatment of dominant-negative mutations. Some rare missense dominant-negative mutations lead to congenital-hearing impairments. A variety of viral vectors have been tested with variable efficacy for...

Modulating Anti-MicroRNA-21 Activity and Specificity Using Oligonucleotide Derivatives and Length Optimization.

ISRN pharmaceutics

Muñoz-Alarcón A, Guterstam P, Romero C, Behlke MA, Lennox KA, Wengel J, El Andaloussi S, Langel U.
PMID: 22474606
ISRN Pharm. 2012;2012:407154. doi: 10.5402/2012/407154. Epub 2012 Feb 07.

MicroRNAs are short, endogenous RNAs that direct posttranscriptional regulation of gene expression vital for many developmental and cellular functions. Implicated in the pathogenesis of several human diseases, this group of RNAs provides interesting targets for therapeutic intervention. Anti-microRNA oligonucleotides...

Applications of cell-penetrating peptides for tumor targeting and future cancer therapies.

Pharmaceuticals (Basel, Switzerland)

Regberg J, Srimanee A, Langel U.
PMID: 24280701
Pharmaceuticals (Basel). 2012 Sep 12;5(9):991-1007. doi: 10.3390/ph5090991.

Cell-penetrating peptides provide a highly promising strategy for intracellular drug delivery. One relevant clinical application of cell-penetrating peptides is cancer therapeutics. Peptide based delivery could increase the uptake of drugs in tumor cells and thereby increase the efficacy of...

Hydrolysis at stepped MgO surfaces.

Physical review letters

Langel W, Parrinello M.
PMID: 10057463
Phys Rev Lett. 1994 Jul 18;73(3):504-507. doi: 10.1103/PhysRevLett.73.504.

No abstract available.

Characterization of a Novel Cytotoxic Cell-penetrating Peptide Derived From p14ARF Protein.

Molecular therapy : the journal of the American Society of Gene Therapy

Johansson HJ, El-Andaloussi S, Holm T, Mäe M, Jänes J, Maimets T, Langel Ü.
PMID: 28192705
Mol Ther. 2008 Jan;16(1):115-123. doi: 10.1038/sj.mt.6300346. Epub 2016 Dec 07.

The tumor suppressor p14ARF is widely deregulated in many types of cancers and is believed to function as a failsafe mechanism, inhibiting proliferation and inducing apoptosis as cellular response to a high oncogene load. We have found that a...

Cell-Penetrating Peptide-Mediated Delivery of Peptide Nucleic Acid (PNA) Oligomers.

CSH protocols

Lundberg P, Kilk K, Langel U.
PMID: 21356781
CSH Protoc. 2008 Mar 01;2008:pdb.prot4889. doi: 10.1101/pdb.prot4889.

INTRODUCTIONTechniques for knockdown of specific genes and nonviral DNA delivery are important for studying protein functions, and are a means for future therapeutics. The problems with many techniques are low bioavailability and toxicity, especially in vivo. Some cationic peptides...

Effect of a Fusion Peptide by Covalent Conjugation of a Mitochondrial Cell-Penetrating Peptide and a Glutathione Analog Peptide.

Molecular therapy. Methods & clinical development

Cerrato CP, Langel Ü.
PMID: 28567432
Mol Ther Methods Clin Dev. 2017 May 04;5:221-231. doi: 10.1016/j.omtm.2017.04.010. eCollection 2017 Jun 16.

Previously, we designed and synthesized a library of mitochondrial antioxidative cell-penetrating peptides (mtCPPs) superior to the parent peptide, SS31, to protect mitochondria from oxidative damage. A library of antioxidative glutathione analogs called glutathione peptides (UPFs), exceptional in hydroxyl radical...

The Gene Toolkit Implicated in Functional Sex in Sparidae Hermaphrodites: Inferences From Comparative Transcriptomics.

Frontiers in genetics

Tsakogiannis A, Manousaki T, Lagnel J, Papanikolaou N, Papandroulakis N, Mylonas CC, Tsigenopoulos CS.
PMID: 30713551
Front Genet. 2019 Jan 18;9:749. doi: 10.3389/fgene.2018.00749. eCollection 2018.

Sex-biased gene expression is the mode through which sex dimorphism arises from a nearly identical genome, especially in organisms without genetic sex determination. Teleost fishes show great variations in the way the sex phenotype forms. Among them, Sparidae, that...

Super-Resolution .

Frontiers in oncology

Iqbal Z, Nguyen D, Hangel G, Motyka S, Bogner W, Jiang S.
PMID: 31649879
Front Oncol. 2019 Oct 09;9:1010. doi: 10.3389/fonc.2019.01010. eCollection 2019.

Magnetic resonance spectroscopic imaging (SI) is a unique imaging technique that provides biochemical information from

Showing 1 to 12 of 152 entries