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Showing 1 to 12 of 210 entries
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Spectroscopy and quantum mechanics of the hydrogen molecular cation: a test of molecular quantum mechanics.

Annual review of physical chemistry

Leach CA, Moss RE.
PMID: 24328942
Annu Rev Phys Chem. 1995;46:55-82. doi: 10.1146/annurev.pc.46.100195.000415.

No abstract available.

Effects of cycloheximide on cellular elongation in aManduca sexta cell line.

Wilhelm Roux's archives of developmental biology

Oberlander H, Leach CE, Lynn DE.
PMID: 28305373
Wilehm Roux Arch Dev Biol. 1981 Jan;190(1):60-61. doi: 10.1007/BF00868706.

A clone (GV1) of the CHIManduca sexta cell line responds to 20-hydroxy-ecdysone by changing cellular shape from an epithelial-like form to an elongated fibroblast-like form. We have determined that this morphological response to hormone is prevented by treatment with...

Paired leaky mode spatial light modulators with a 28° total deflection angle.

Optics letters

Qaderi K, Leach C, Smalley DE.
PMID: 28362765
Opt Lett. 2017 Apr 01;42(7):1345-1348. doi: 10.1364/OL.42.001345.

In this Letter, we present a paired set of waveguide spatial light modulators (SLMs) capable of a maximum light deflection nearing 28° for red. This deflection, which is several times larger than the angular sweep of current, state-of-the-art modulators,...

Modeling fragile X syndrome in the Fmr1 knockout mouse.

Intractable & rare diseases research

Kazdoba TM, Leach PT, Silverman JL, Crawley JN.
PMID: 25606362
Intractable Rare Dis Res. 2014 Nov;3(4):118-33. doi: 10.5582/irdr.2014.01024.

Fragile X Syndrome (FXS) is a commonly inherited form of intellectual disability and one of the leading genetic causes for autism spectrum disorder. Clinical symptoms of FXS can include impaired cognition, anxiety, hyperactivity, social phobia, and repetitive behaviors. FXS...

Partial Thickness Rotator Cuff Tears: Current Concepts.

Advances in orthopedics

Matthewson G, Beach CJ, Nelson AA, Woodmass JM, Ono Y, Boorman RS, Lo IK, Thornton GM.
PMID: 26171251
Adv Orthop. 2015;2015:458786. doi: 10.1155/2015/458786. Epub 2015 Jun 11.

Partial thickness rotator cuff tears are a common cause of pain in the adult shoulder. Despite their high prevalence, the diagnosis and treatment of partial thickness rotator cuff tears remains controversial. While recent studies have helped to elucidate the...

PLUMS: a program for the rapid optimization of focused libraries.

Journal of chemical information and computer sciences

Bravi G, Green DV, Hann MM, Leach AR.
PMID: 11128103
J Chem Inf Comput Sci. 2000 Nov-Dec;40(6):1441-8. doi: 10.1021/ci000389+.

PLUMS is a new method to perform rational monomer selection for combinatorial chemistry libraries. The algorithm has been developed to optimize focused libraries with specific two-dimensional and/or three-dimensional properties. A preliminary step is the identification of those molecules in...

Preparing for the MRCGP examination--membership of the Royal College of General Practitioners.

Journal of the Royal Army Medical Corps

Coombe MD, Leach AJ.
PMID: 12024898
J R Army Med Corps. 2002 Mar;148(1):80-6. doi: 10.1136/jramc-148-01-15.

No abstract available.

The in silico world of virtual libraries.

Drug discovery today

Leach AR, Hann MM.
PMID: 10893546
Drug Discov Today. 2000 Aug;5(8):326-336. doi: 10.1016/s1359-6446(00)01516-6.

Combinatorial chemistry has provided medicinal chemists with an unprecedented ability to synthesize large numbers of molecules. However, early experience was that this did not result in any increase in the number of real candidates for lead optimization. Attention has...

On the elastic modulus of metallic nanowires.

Nano letters

McDowell MT, Leach AM, Gall K.
PMID: 18947212
Nano Lett. 2008 Nov;8(11):3613-8. doi: 10.1021/nl801526c. Epub 2008 Oct 24.

Previous atomistic simulations and experiments have attributed size effects in the elastic modulus of Ag nanowires to surface energy effects inherent to metallic surfaces. However, differences in experimental and computational trends analyzed here imply that other factors are controlling...

The B chromosomes in Brachycome.

Cytogenetic and genome research

Leach CR, Houben A, Timmis JN.
PMID: 15292592
Cytogenet Genome Res. 2004;106(2):199-209. doi: 10.1159/000079288.

This review presents a historical account of studies of B chromosomes in the genus Brachycome Cass. (synonym: Brachyscome) from the earliest cytological investigations carried out in the late 1960s though to the most recent molecular analyses. Molecular analyses provide...

Measuring nasal bacterial load and its association with otitis media.

BMC ear, nose, and throat disorders

Smith-Vaughan H, Byun R, Nadkarni M, Jacques NA, Hunter N, Halpin S, Morris PS, Leach AJ.
PMID: 16686940
BMC Ear Nose Throat Disord. 2006 May 10;6:10. doi: 10.1186/1472-6815-6-10.

BACKGROUND: Nasal colonisation with otitis media (OM) pathogens, particularly Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis, is a precursor to the onset of OM. Many children experience asymptomatic nasal carriage of these pathogens whereas others will progress to otitis...

Local variability in PTC thermistor grain boundary structures.

Scanning

Leach C, Seaton J.
PMID: 18618600
Scanning. 2008 Jul-Aug;30(4):339-46. doi: 10.1002/sca.20117.

Scanning electron microscopy-based conductive mode (CM) microscopy, using the remote electron beam-induced current configuration, was carried out on a positive temperature coefficient of resistance thermistor at temperatures below and above the Curie temperature, T(C). Below T(C), when the thermistor...

Showing 1 to 12 of 210 entries