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Showing 1 to 12 of 128 entries
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Tapentadol extended release in the management of peripheral diabetic neuropathic pain.

Therapeutics and clinical risk management

Vadivelu N, Kai A, Maslin B, Kodumudi G, Legler A, Berger JM.
PMID: 25609974
Ther Clin Risk Manag. 2015 Jan 14;11:95-105. doi: 10.2147/TCRM.S32193. eCollection 2015.

Tapentadol, a μ-opioid agonist and norepinephrine reuptake inhibitor, has been found to be an effective medication for a wide variety of chronic pain conditions, including back pain, cancer-related pain, and arthritic pain. It has also been found to have...

Phenotypic variation in dorsal fin morphology of coastal bottlenose dolphins (.

PeerJ

Morteo E, Rocha-Olivares A, Morteo R, Weller DW.
PMID: 28626607
PeerJ. 2017 Jun 13;5:e3415. doi: 10.7717/peerj.3415. eCollection 2017.

Geographic variation in external morphology is thought to reflect an interplay between genotype and the environment. Morphological variation has been well-described for a number of cetacean species, including the bottlenose dolphin (

RESPONSE: re: brain and other central nervous system cancers: recent trends in incidence and mortality.

Journal of the National Cancer Institute

Legler JM, Gloeckler Ries LA, Smith MA, Warren JL, Heineman EF, Kaplan RS, Linet MS.
PMID: 10620639
J Natl Cancer Inst. 2000 Jan 05;92(1):77A-8. doi: 10.1093/jnci/92.1.77a.

No abstract available.

Integrating a family-centered approach into social work practice with families of children and adolescents with disabilities.

Journal of social work in disability & rehabilitation

Strock-Lynskey D, Keller DW.
PMID: 17989025
J Soc Work Disabil Rehabil. 2006;6(1):111-34. doi: 10.1300/j198v06n01_07.

This article identifies a family-centered practice construct for working with children and adolescents with disabilities and their families. The experiences of these families have shifted considerably over the past 30 years. A legislative and historical context provides the basis...

Trimethylsilylmethyl complexes of the rare-earth metals with sterically hindered N-heterocyclic carbene ligands: adduct formation and C-H bond activation.

Dalton transactions (Cambridge, England : 2003)

Fegler W, Spaniol TP, Okuda J.
PMID: 20428582
Dalton Trans. 2010 Aug 07;39(29):6774-9. doi: 10.1039/c001699c. Epub 2010 Apr 28.

Tris(trimethylsilylmethyl) complexes of yttrium and lutetium [LnR(3)(THF)(2)] (R = CH(2)SiMe(3)) were treated with sterically bulky N-heterocyclic carbenes (NHC) 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene (IPr) and 1,3-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene (IMes). IPr gave labile mono-adducts [LnR(3)(NHC)], isolated as thermally robust crystals and fully characterized by NMR spectroscopy...

Effects of inbreeding on male function and self-fertility in the partially self-incompatible herb Campanula rapunculoides (Campanulaceae).

American journal of botany

Good-Avila SV, Nagel T, Vogler DW, Stephenson AG.
PMID: 21653350
Am J Bot. 2003 Dec;90(12):1736-45. doi: 10.3732/ajb.90.12.1736.

We examined the effect of inbreeding on fitness (through both male and female functions) and changes in self-fertility in the partially self-incompatible species Campanula rapunculoides. Individuals in natural populations of C. rapunculoides varied extensively in their strength of self-incompatibility...

Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity.

Environmental toxicology and pharmacology

van Lipzig MM, Vermeulen NP, Gusinu R, Legler J, Frank H, Seidel A, Meerman JH.
PMID: 21783461
Environ Toxicol Pharmacol. 2005 Jan;19(1):41-55. doi: 10.1016/j.etap.2004.03.010.

Metabolism of polycyclic aromatic hydrocarbons (PAHs) has been studied intensively, and potential metabolites with estrogenic activity have been identified previously. However, little attention has been paid to the metabolic pathways in mammalians and to the combined effect of individual...

Development of organophosphate hydrolase activity in a bacterial homolog of human cholinesterase.

Frontiers in chemistry

Legler PM, Boisvert SM, Compton JR, Millard CB.
PMID: 25077141
Front Chem. 2014 Jul 16;2:46. doi: 10.3389/fchem.2014.00046. eCollection 2014.

We applied a combination of rational design and directed evolution (DE) to Bacillus subtilis p-nitrobenzyl esterase (pNBE) with the goal of enhancing organophosphorus acid anhydride hydrolase (OPAAH) activity. DE started with a designed variant, pNBE A107H, carrying a histidine...

Genome-enabled studies of anaerobic, nitrate-dependent iron oxidation in the chemolithoautotrophic bacterium Thiobacillus denitrificans.

Frontiers in microbiology

Beller HR, Zhou P, Legler TC, Chakicherla A, Kane S, Letain TE, A O'Day P.
PMID: 24065960
Front Microbiol. 2013 Aug 27;4:249. doi: 10.3389/fmicb.2013.00249. eCollection 2013.

Thiobacillus denitrificans is a chemolithoautotrophic bacterium capable of anaerobic, nitrate-dependent U(IV) and Fe(II) oxidation, both of which can strongly influence the long-term efficacy of in situ reductive immobilization of uranium in contaminated aquifers. We previously identified two c-type cytochromes...

Unbiased Analysis of Item-Specific Multi-Voxel Activation Patterns Across Learning.

Frontiers in neuroscience

Ruge H, Legler E, Schäfer TAJ, Zwosta K, Wolfensteller U, Mohr H.
PMID: 30337852
Front Neurosci. 2018 Oct 04;12:723. doi: 10.3389/fnins.2018.00723. eCollection 2018.

Recent work has highlighted that multi-voxel pattern analysis (MVPA) can be severely biased when BOLD response estimation involves systematic imbalance in model regressor correlations. This problem occurs in situations where trial types of interest are temporally dependent and the...

Digitization workflows for flat sheets and packets of plants, algae, and fungi.

Applications in plant sciences

Nelson G, Sweeney P, Wallace LE, Rabeler RK, Allard D, Brown H, Carter JR, Denslow MW, Ellwood ER, Germain-Aubrey CC, Gilbert E, Gillespie E, Goertzen LR, Legler B, Marchant DB, Marsico TD, Morris AB, Murrell Z, Nazaire M, Neefus C, Oberreiter S, Paul D, Ruhfel BR, Sasek T, Shaw J, Soltis PS, Watson K, Weeks A, Mast AR.
PMID: 26421256
Appl Plant Sci. 2015 Sep 10;3(9). doi: 10.3732/apps.1500065. eCollection 2015 Sep.

Effective workflows are essential components in the digitization of biodiversity specimen collections. To date, no comprehensive, community-vetted workflows have been published for digitizing flat sheets and packets of plants, algae, and fungi, even though latest estimates suggest that only...

Rhodium Oxide Surface-Loaded Gas Sensors.

Nanomaterials (Basel, Switzerland)

Staerz A, Boehme I, Degler D, Bahri M, Doronkin DE, Zimina A, Brinkmann H, Herrmann S, Junker B, Ersen O, Grunwaldt JD, Weimar U, Barsan N.
PMID: 30388804
Nanomaterials (Basel). 2018 Nov 01;8(11). doi: 10.3390/nano8110892.

In order to increase their stability and tune-sensing characteristics, metal oxides are often surface-loaded with noble metals. Although a great deal of empirical work shows that surface-loading with noble metals drastically changes sensing characteristics, little information exists on the...

Showing 1 to 12 of 128 entries