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Showing 1 to 12 of 1127 entries
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Over-and underrepresentation of short DNA words in herpesvirus genomes

Science and underrepresentation

Leung MY, Speed TP.
GSID: QOaYS4iOTV4J
MY Leung, GM Marsh, TP Speed - Journal of Computational …, 1996 - liebertpub.com

… over-and underrepresentation of short words are statistical aspects of DNA sequences with potential biological relevance, the methods of quantifying over- and underrepresentation are …

Development of contextually-relevant sexuality education: Lessons from a comprehensive review of adolescent sexuality education across cultures

Asset based approaches STEM training

Leung H, Shek DTL.
GSID: hiweBV6cD4UJ
H Leung, DTL Shek, E Leung, EYW Shek - International journal of …, 2019 - mdpi.com

… it comes to the topic of safe sex education, it created discomfort in most teachers as nearly all training programs stem from the abstinence-based approach [71]. This issue still remains …

Evidence that phospholipase C is involved in the antitumour action of NSC768313, a new thieno[2,3-b]pyridine derivative.

Cancer cell international

Reynisson J, Jaiswal JK, Barker D, D'mello SA, Denny WA, Baguley BC, Leung EY.
PMID: 26966420
Cancer Cell Int. 2016 Mar 10;16:18. doi: 10.1186/s12935-016-0293-6. eCollection 2016.

BACKGROUND: The thieno[2,3-b]pyridines were discovered by virtual high throughput screening as potential inhibitors of phospholipase C (PLC) isoforms and showed potent growth inhibitory effects in National Cancer Institute's human tumour cell line panel (NCI60). The mechanism of the anti-proliferative...

The gas-phase structure of the asymmetric, trans-dinitrogen tetroxide (N.

The Journal of chemical physics

Seifert NA, Zaleski DP, Fehnel R, Goswami M, Pate BH, Lehmann KK, Leung HO, Marshall MD, Stanton JF.
PMID: 28390374
J Chem Phys. 2017 Apr 07;146(13):134305. doi: 10.1063/1.4979182.

We report the first experimental gas-phase observation of an asymmetric, trans-N

Log-Euclidean Metrics for Contrast Preserving Decolorization.

IEEE transactions on image processing : a publication of the IEEE Signal Processing Society

Qiegen Liu, Guangpu Shao, Yuhao Wang, Junbin Gao, Leung H.
PMID: 28858795
IEEE Trans Image Process. 2017 Dec;26(12):5772-5783. doi: 10.1109/TIP.2017.2745104. Epub 2017 Aug 25.

This paper presents a novel Log-Euclidean metric inspired color-to-gray conversion model for faithfully preserving the contrast details of color image, which differs from the traditional Euclidean metric approaches. In the proposed model, motivated by the fact that Log-Euclidean metric...

Analysis of Allelic Imbalance in Rice Hybrids Under Water Stress and Association of Asymmetrically Expressed Genes with Drought-Response QTLs.

Rice (New York, N.Y.)

Ereful NC, Liu LY, Tsai E, Kao SM, Dixit S, Mauleon R, Malabanan K, Thomson M, Laurena A, Lee D, Mackay I, Greenland A, Powell W, Leung H.
PMID: 27671164
Rice (N Y). 2016 Dec;9(1):50. doi: 10.1186/s12284-016-0123-4. Epub 2016 Sep 26.

BACKGROUND: Information on the effect of stress on the allele-specific expression (ASE) profile of rice hybrids is limited. More so, the association of allelically imbalanced genes to important traits is yet to be understood. Here we assessed allelic imbalance...

Comparative genomic analysis reveals genetic features related to the virulence of .

Gut pathogens

Koo HJ, Ahn S, Chung HY, Kim S, Kim K, Ryu S, Lee JH, Choi SH, Kim H.
PMID: 28515790
Gut Pathog. 2017 May 15;9:29. doi: 10.1186/s13099-017-0175-z. eCollection 2017.

RESULTS: We fully assembled the single circular chromosome (5,418,913 bp) and one plasmid (259,749 bp); 5511 open reading frames (ORFs) and 283 ORFs were predicted for the chromosome and plasmid, respectively. Moreover, we detected that the enterotoxin (NHE, HBL,...

Clinical Experience of the Klippel-Trenaunay Syndrome.

Archives of plastic surgery

Sung HM, Chung HY, Lee SJ, Lee JM, Huh S, Lee JW, Choi KY, Yang JD, Cho BC.
PMID: 26430625
Arch Plast Surg. 2015 Sep;42(5):552-8. doi: 10.5999/aps.2015.42.5.552. Epub 2015 Sep 15.

BACKGROUND: The Klippel-Trenaunay syndrome (KTS) is characterized by three clinical features, namely cutaneous capillary malformations, venous malformations, and soft tissue and/or bony hypertrophy of the extremities. The varied manifestations are attributed to the unpredictable clinical nature and prognosis of...

Therapeutic drug monitoring of mexiletine at a large academic medical center.

SAGE open medicine

Nei SD, Danelich IM, Lose JM, Leung LY, Asirvatham SJ, McLeod CJ.
PMID: 27708780
SAGE Open Med. 2016 Sep 21;4:2050312116670659. doi: 10.1177/2050312116670659. eCollection 2016.

INTRODUCTION: The therapeutic trough range for mexiletine (0.8-2 mcg/mL) was largely established in the setting of arrhythmia prophylaxis following myocardial infarction.OBJECTIVE: Describe the usage patterns of serum mexiletine concentrations and the impact of these concentrations on mexiletine dosing in...

Preimplantation genetic diagnosis for hereditary cancer syndrome: local experience.

Hong Kong medical journal = Xianggang yi xue za zhi

Lee VC, Chow JF, Lau EY, Kwong A, Leung SY, Yeung WS, Ho PC, Ng EH.
PMID: 27305697
Hong Kong Med J. 2016 Jun;22(3):289-91. doi: 10.12809/hkmj144499.

No abstract available.

FLT3 inhibitors: clinical potential in acute myeloid leukemia.

OncoTargets and therapy

Hospital MA, Green AS, Maciel TT, Moura IC, Leung AY, Bouscary D, Tamburini J.
PMID: 28223820
Onco Targets Ther. 2017 Feb 03;10:607-615. doi: 10.2147/OTT.S103790. eCollection 2017.

Acute myeloid leukemia (AML) is an aggressive hematopoietic malignancy that is cured in as few as 15%-40% of cases. Tremendous improvements in AML prognostication arose from a comprehensive analysis of leukemia cell genomes. Among normal karyotype AML cases, mutations...

Freezing-enhanced reduction of chromate by nitrite.

The Science of the total environment

Kim K, Chung HY, Ju J, Kim J.
PMID: 28262362
Sci Total Environ. 2017 Jul 15;590:107-113. doi: 10.1016/j.scitotenv.2017.02.176. Epub 2017 Mar 03.

The redox reactions between pollutants and chemicals (e.g., pollutant, oxygen, and water) critically affect the fate and potential risk of pollutants, and their rates significantly depend on the environmental media. Although the kinetics and mechanism of various redox reactions...

Showing 1 to 12 of 1127 entries