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Over-and underrepresentation of short DNA words in herpesvirus genomes

Science and underrepresentation

Leung MY, Speed TP.
GSID: QOaYS4iOTV4J
MY Leung, GM Marsh, TP Speed - Journal of Computational …, 1996 - liebertpub.com

… over-and underrepresentation of short words are statistical aspects of DNA sequences with potential biological relevance, the methods of quantifying over- and underrepresentation are …

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Leung, M. Y., Marsh, G. M., & Speed, T. P. (1996). Over-and underrepresentation of short DNA words in herpesvirus genomes. Journal of Computational Biology, 3(3), 345-360.
Leung, Ming-Ying, Genevieve M. Marsh, and Terence P. Speed. "Over-and underrepresentation of short DNA words in herpesvirus genomes." Journal of Computational Biology 3.3 (1996): 345-360.
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Gender representation in US biomedical informatics leadership and recognition

workforce diversity

Griffin AC, Leung TI, Tenenbaum JD.
GSID: VCqUSleiTMEJ
AC Griffin, TI Leung, JD Tenenbaum… - Journal of the …, 2021 - academic.oup.com

Objective This study sought to describe gender representation in leadership and recognition within the US biomedical informatics community. Materials and Methods Data were collected …

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Griffin, A. C., Leung, T. I., Tenenbaum, J. D., & Chung, A. E. (2021). Gender representation in US biomedical informatics leadership and recognition. Journal of the American Medical Informatics Association, 28(6), 1270-1274.
Griffin, Ashley C., et al. "Gender representation in US biomedical informatics leadership and recognition." Journal of the American Medical Informatics Association 28.6 (2021): 1270-1274.
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Evidence that phospholipase C is involved in the antitumour action of NSC768313, a new thieno[2,3-b]pyridine derivative.

Cancer cell international

Reynisson J, Jaiswal JK, Barker D, D'mello SA, Denny WA, Baguley BC, Leung EY.
PMID: 26966420
Cancer Cell Int. 2016 Mar 10;16:18. doi: 10.1186/s12935-016-0293-6. eCollection 2016.

BACKGROUND: The thieno[2,3-b]pyridines were discovered by virtual high throughput screening as potential inhibitors of phospholipase C (PLC) isoforms and showed potent growth inhibitory effects in National Cancer Institute's human tumour cell line panel (NCI60). The mechanism of the anti-proliferative...

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Reynisson J, Jaiswal JK, Barker D, et al. Evidence that phospholipase C is involved in the antitumour action of NSC768313, a new thieno[2,3-b]pyridine derivative. Cancer Cell Int. 2016;16:18doi: 10.1186/s12935-016-0293-6.
Reynisson, J., Jaiswal, J. K., Barker, D., D'mello, S. A., Denny, W. A., Baguley, B. C., & Leung, E. Y. (2016). Evidence that phospholipase C is involved in the antitumour action of NSC768313, a new thieno[2,3-b]pyridine derivative. Cancer cell international, 1618. https://doi.org/10.1186/s12935-016-0293-6
Reynisson, Jóhannes, et al. "Evidence that phospholipase C is involved in the antitumour action of NSC768313, a new thieno[2,3-b]pyridine derivative." Cancer cell international vol. 16 (2016): 18. doi: https://doi.org/10.1186/s12935-016-0293-6
Reynisson J, Jaiswal JK, Barker D, D'mello SA, Denny WA, Baguley BC, Leung EY. Evidence that phospholipase C is involved in the antitumour action of NSC768313, a new thieno[2,3-b]pyridine derivative. Cancer Cell Int. 2016 Mar 10;16:18. doi: 10.1186/s12935-016-0293-6. eCollection 2016. PMID: 26966420; PMCID: PMC4785615.
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Therapeutic drug monitoring of mexiletine at a large academic medical center.

SAGE open medicine

Nei SD, Danelich IM, Lose JM, Leung LY, Asirvatham SJ, McLeod CJ.
PMID: 27708780
SAGE Open Med. 2016 Sep 21;4:2050312116670659. doi: 10.1177/2050312116670659. eCollection 2016.

INTRODUCTION: The therapeutic trough range for mexiletine (0.8-2 mcg/mL) was largely established in the setting of arrhythmia prophylaxis following myocardial infarction.OBJECTIVE: Describe the usage patterns of serum mexiletine concentrations and the impact of these concentrations on mexiletine dosing in...

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Nei SD, Danelich IM, Lose JM, et al. Therapeutic drug monitoring of mexiletine at a large academic medical center. SAGE Open Med. 2016;4:2050312116670659doi: 10.1177/2050312116670659.
Nei, S. D., Danelich, I. M., Lose, J. M., Leung, L. Y., Asirvatham, S. J., & McLeod, C. J. (2016). Therapeutic drug monitoring of mexiletine at a large academic medical center. SAGE open medicine, 42050312116670659. https://doi.org/10.1177/2050312116670659
Nei, Scott D, et al. "Therapeutic drug monitoring of mexiletine at a large academic medical center." SAGE open medicine vol. 4 (2016): 2050312116670659. doi: https://doi.org/10.1177/2050312116670659
Nei SD, Danelich IM, Lose JM, Leung LY, Asirvatham SJ, McLeod CJ. Therapeutic drug monitoring of mexiletine at a large academic medical center. SAGE Open Med. 2016 Sep 21;4:2050312116670659. doi: 10.1177/2050312116670659. eCollection 2016. PMID: 27708780; PMCID: PMC5034464.
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Preimplantation genetic diagnosis for hereditary cancer syndrome: local experience.

Hong Kong medical journal = Xianggang yi xue za zhi

Lee VC, Chow JF, Lau EY, Kwong A, Leung SY, Yeung WS, Ho PC, Ng EH.
PMID: 27305697
Hong Kong Med J. 2016 Jun;22(3):289-91. doi: 10.12809/hkmj144499.

No abstract available.

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Lee VC, Chow JF, Lau EY, et al. Preimplantation genetic diagnosis for hereditary cancer syndrome: local experience. Hong Kong Med J. 2016;22(3):289-91doi: 10.12809/hkmj144499.
Lee, V. C., Chow, J. F., Lau, E. Y., Kwong, A., Leung, S. Y., Yeung, W. S., Ho, P. C., & Ng, E. H. (2016). Preimplantation genetic diagnosis for hereditary cancer syndrome: local experience. Hong Kong medical journal = Xianggang yi xue za zhi, 22(3), 289-91. https://doi.org/10.12809/hkmj144499
Lee, V Cy, et al. "Preimplantation genetic diagnosis for hereditary cancer syndrome: local experience." Hong Kong medical journal = Xianggang yi xue za zhi vol. 22,3 (2016): 289-91. doi: https://doi.org/10.12809/hkmj144499
Lee VC, Chow JF, Lau EY, Kwong A, Leung SY, Yeung WS, Ho PC, Ng EH. Preimplantation genetic diagnosis for hereditary cancer syndrome: local experience. Hong Kong Med J. 2016 Jun;22(3):289-91. doi: 10.12809/hkmj144499. PMID: 27305697.
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FLT3 inhibitors: clinical potential in acute myeloid leukemia.

OncoTargets and therapy

Hospital MA, Green AS, Maciel TT, Moura IC, Leung AY, Bouscary D, Tamburini J.
PMID: 28223820
Onco Targets Ther. 2017 Feb 03;10:607-615. doi: 10.2147/OTT.S103790. eCollection 2017.

Acute myeloid leukemia (AML) is an aggressive hematopoietic malignancy that is cured in as few as 15%-40% of cases. Tremendous improvements in AML prognostication arose from a comprehensive analysis of leukemia cell genomes. Among normal karyotype AML cases, mutations...

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Hospital MA, Green AS, Maciel TT, et al. FLT3 inhibitors: clinical potential in acute myeloid leukemia. Onco Targets Ther. 2017;10:607-615doi: 10.2147/OTT.S103790.
Hospital, M. A., Green, A. S., Maciel, T. T., Moura, I. C., Leung, A. Y., Bouscary, D., & Tamburini, J. (2017). FLT3 inhibitors: clinical potential in acute myeloid leukemia. OncoTargets and therapy, 10607-615. https://doi.org/10.2147/OTT.S103790
Hospital, Marie-Anne, et al. "FLT3 inhibitors: clinical potential in acute myeloid leukemia." OncoTargets and therapy vol. 10 (2017): 607-615. doi: https://doi.org/10.2147/OTT.S103790
Hospital MA, Green AS, Maciel TT, Moura IC, Leung AY, Bouscary D, Tamburini J. FLT3 inhibitors: clinical potential in acute myeloid leukemia. Onco Targets Ther. 2017 Feb 03;10:607-615. doi: 10.2147/OTT.S103790. eCollection 2017. PMID: 28223820; PMCID: PMC5304990.
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Toward an Objective Diagnostic Test for Bacterial Cellulitis.

PloS one

Pallin DJ, Bry L, Dwyer RC, Lipworth AD, Leung DY, Camargo CA, Kupper TS, Filbin MR, Murphy GF.
PMID: 27656884
PLoS One. 2016 Sep 22;11(9):e0162947. doi: 10.1371/journal.pone.0162947. eCollection 2016.

BACKGROUND: Prior studies repeatedly showed that cultures of skin lesions diagnosed as "cellulitis" are usually negative. However, lack of a gold standard for diagnosis (against which culture might be judged) and failure to assess the human immune response are...

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Pallin DJ, Bry L, Dwyer RC, et al. Toward an Objective Diagnostic Test for Bacterial Cellulitis. PLoS One. 2016;11(9):e0162947doi: 10.1371/journal.pone.0162947.
Pallin, D. J., Bry, L., Dwyer, R. C., Lipworth, A. D., Leung, D. Y., Camargo, C. A., Kupper, T. S., Filbin, M. R., & Murphy, G. F. (2016). Toward an Objective Diagnostic Test for Bacterial Cellulitis. PloS one, 11(9), e0162947. https://doi.org/10.1371/journal.pone.0162947
Pallin, Daniel J, et al. "Toward an Objective Diagnostic Test for Bacterial Cellulitis." PloS one vol. 11,9 (2016): e0162947. doi: https://doi.org/10.1371/journal.pone.0162947
Pallin DJ, Bry L, Dwyer RC, Lipworth AD, Leung DY, Camargo CA, Kupper TS, Filbin MR, Murphy GF. Toward an Objective Diagnostic Test for Bacterial Cellulitis. PLoS One. 2016 Sep 22;11(9):e0162947. doi: 10.1371/journal.pone.0162947. eCollection 2016. PMID: 27656884; PMCID: PMC5033594.
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The reliability and validity of the pain items of the Hong Kong version interRAI community health assessment for community-dwelling elders in Hong Kong.

Journal of clinical nursing

Liu JY, Chi I, Chan KS, Lai CK, Leung AY.
PMID: 26041334
J Clin Nurs. 2015 Aug;24(15):2352-4. doi: 10.1111/jocn.12885. Epub 2015 Jun 03.

No abstract available.

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Liu JY, Chi I, Chan KS, et al. The reliability and validity of the pain items of the Hong Kong version interRAI community health assessment for community-dwelling elders in Hong Kong. J Clin Nurs. 2015;24(15):2352-4doi: 10.1111/jocn.12885.
Liu, J. Y., Chi, I., Chan, K. S., Lai, C. K., & Leung, A. Y. (2015). The reliability and validity of the pain items of the Hong Kong version interRAI community health assessment for community-dwelling elders in Hong Kong. Journal of clinical nursing, 24(15), 2352-4. https://doi.org/10.1111/jocn.12885
Liu, Justina Y W, et al. "The reliability and validity of the pain items of the Hong Kong version interRAI community health assessment for community-dwelling elders in Hong Kong." Journal of clinical nursing vol. 24,15 (2015): 2352-4. doi: https://doi.org/10.1111/jocn.12885
Liu JY, Chi I, Chan KS, Lai CK, Leung AY. The reliability and validity of the pain items of the Hong Kong version interRAI community health assessment for community-dwelling elders in Hong Kong. J Clin Nurs. 2015 Aug;24(15):2352-4. doi: 10.1111/jocn.12885. Epub 2015 Jun 03. PMID: 26041334.
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Predictors of good functional outcome in counterpulsation-treated recent ischaemic stroke patients.

BMJ open

Lin W, Han J, Chen X, Xiong L, Leung HW, Leung TW, Soo Y, Wong LK.
PMID: 23794561
BMJ Open. 2013 Jun 20;3(6). doi: 10.1136/bmjopen-2013-002932.

OBJECTIVES: External counterpulsation (ECP) is a non-invasive method being investigated for ischaemic stroke. We aimed to explore predictors of good functional outcome for ECP-treated ischaemic stroke patients who completed a minimum of 10 sessions.METHODS: We analysed our ECP registry...

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Lin W, Han J, Chen X, et al. Predictors of good functional outcome in counterpulsation-treated recent ischaemic stroke patients. BMJ Open. 2013;3(6)doi: 10.1136/bmjopen-2013-002932.
Lin, W., Han, J., Chen, X., Xiong, L., Leung, H. W., Leung, T. W., Soo, Y., & Wong, L. K. (2013). Predictors of good functional outcome in counterpulsation-treated recent ischaemic stroke patients. BMJ open, 3(6), . https://doi.org/10.1136/bmjopen-2013-002932
Lin, Wenhua, et al. "Predictors of good functional outcome in counterpulsation-treated recent ischaemic stroke patients." BMJ open vol. 3,6 (2013). doi: https://doi.org/10.1136/bmjopen-2013-002932
Lin W, Han J, Chen X, Xiong L, Leung HW, Leung TW, Soo Y, Wong LK. Predictors of good functional outcome in counterpulsation-treated recent ischaemic stroke patients. BMJ Open. 2013 Jun 20;3(6). doi: 10.1136/bmjopen-2013-002932. PMID: 23794561; PMCID: PMC3686252.
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AMP-activated protein kinase (AMPK) as a potential therapeutic target independent of PI3K/Akt signaling in prostate cancer.

Oncoscience

Choudhury Y, Yang Z, Ahmad I, Nixon C, Salt IP, Leung HY.
PMID: 25594043
Oncoscience. 2014 Jun 04;1(6):446-56. doi: 10.18632/oncoscience.49. eCollection 2014.

Depletion of cellular energy activates the AMP-activated kinase (AMPK) to favor energy-producing catabolic processes during tumorigenesis. Using a panel of in vitro cell lines and resected tumors, we investigated the therapeutic value of manipulating AMPK in prostate cancer (PC)....

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Choudhury Y, Yang Z, Ahmad I, et al. AMP-activated protein kinase (AMPK) as a potential therapeutic target independent of PI3K/Akt signaling in prostate cancer. Oncoscience. 2014;1(6):446-56doi: 10.18632/oncoscience.49.
Choudhury, Y., Yang, Z., Ahmad, I., Nixon, C., Salt, I. P., & Leung, H. Y. (2014). AMP-activated protein kinase (AMPK) as a potential therapeutic target independent of PI3K/Akt signaling in prostate cancer. Oncoscience, 1(6), 446-56. https://doi.org/10.18632/oncoscience.49
Choudhury, Yashmin, et al. "AMP-activated protein kinase (AMPK) as a potential therapeutic target independent of PI3K/Akt signaling in prostate cancer." Oncoscience vol. 1,6 (2014): 446-56. doi: https://doi.org/10.18632/oncoscience.49
Choudhury Y, Yang Z, Ahmad I, Nixon C, Salt IP, Leung HY. AMP-activated protein kinase (AMPK) as a potential therapeutic target independent of PI3K/Akt signaling in prostate cancer. Oncoscience. 2014 Jun 04;1(6):446-56. doi: 10.18632/oncoscience.49. eCollection 2014. PMID: 25594043; PMCID: PMC4284621.
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Moyamoya disease in a patient with neuromyelitis optica.

Oxford medical case reports

Chan NH, Ip VH, Au L, Siu D, Leung T, Xiong L, Wong KS, Haspekian M.
PMID: 25988010
Oxf Med Case Reports. 2014 Apr 08;2014(1):13-5. doi: 10.1093/omcr/omu006. eCollection 2014 Apr.

Moyamoya disease can be associated with autoimmune disease such as thyrotoxicosis, but there has been only one report of association with neuromyelitis optica (NMO). We report another case of this combination with the presence of anti-SSA antibody in addition...

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Chan NH, Ip VH, Au L, et al. Moyamoya disease in a patient with neuromyelitis optica. Oxf Med Case Reports. 2014;2014(1):13-5doi: 10.1093/omcr/omu006.
Chan, N. H., Ip, V. H., Au, L., Siu, D., Leung, T., Xiong, L., Wong, K. S., & Haspekian, M. (2014). Moyamoya disease in a patient with neuromyelitis optica. Oxford medical case reports, 2014(1), 13-5. https://doi.org/10.1093/omcr/omu006
Chan, Nathan H, et al. "Moyamoya disease in a patient with neuromyelitis optica." Oxford medical case reports vol. 2014,1 (2014): 13-5. doi: https://doi.org/10.1093/omcr/omu006
Chan NH, Ip VH, Au L, Siu D, Leung T, Xiong L, Wong KS, Haspekian M. Moyamoya disease in a patient with neuromyelitis optica. Oxf Med Case Reports. 2014 Apr 08;2014(1):13-5. doi: 10.1093/omcr/omu006. eCollection 2014 Apr. PMID: 25988010; PMCID: PMC4369969.
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Screening neonatal jaundice based on the sclera color of the eye using digital photography.

Biomedical optics express

Leung TS, Kapur K, Guilliam A, Okell J, Lim B, MacDonald LW, Meek J.
PMID: 26601015
Biomed Opt Express. 2015 Oct 23;6(11):4529-38. doi: 10.1364/BOE.6.004529. eCollection 2015 Nov 01.

A new screening technique for neonatal jaundice is proposed exploiting the yellow discoloration in the sclera. It involves taking digital photographs of newborn infants' eyes (n = 110) and processing the pixel colour values of the sclera to predict...

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Leung TS, Kapur K, Guilliam A, et al. Screening neonatal jaundice based on the sclera color of the eye using digital photography. Biomed Opt Express. 2015;6(11):4529-38doi: 10.1364/BOE.6.004529.
Leung, T. S., Kapur, K., Guilliam, A., Okell, J., Lim, B., MacDonald, L. W., & Meek, J. (2015). Screening neonatal jaundice based on the sclera color of the eye using digital photography. Biomedical optics express, 6(11), 4529-38. https://doi.org/10.1364/BOE.6.004529
Leung, Terence S, et al. "Screening neonatal jaundice based on the sclera color of the eye using digital photography." Biomedical optics express vol. 6,11 (2015): 4529-38. doi: https://doi.org/10.1364/BOE.6.004529
Leung TS, Kapur K, Guilliam A, Okell J, Lim B, MacDonald LW, Meek J. Screening neonatal jaundice based on the sclera color of the eye using digital photography. Biomed Opt Express. 2015 Oct 23;6(11):4529-38. doi: 10.1364/BOE.6.004529. eCollection 2015 Nov 01. PMID: 26601015; PMCID: PMC4646559.
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Showing 1 to 12 of 710 entries