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Tight junction physiology of pleural mesothelium.

Frontiers in physiology

Markov AG, Amasheh S.
PMID: 25009499
Front Physiol. 2014 Jun 24;5:221. doi: 10.3389/fphys.2014.00221. eCollection 2014.

Pleura consists of visceral and parietal cell layers, producing a fluid, which is necessary for lubrication of the pleural space. Function of both mesothelial cell layers is necessary for the regulation of a constant pleural fluid volume and composition...

Quinox, a quinoline-type N-oxide, as organocatalyst in the asymmetric allylation of aromatic aldehydes with allyltrichlorosilanes: the role of arene-arene interactions.

Angewandte Chemie (International ed. in English)

Malkov AV, Dufková L, Farrugia L, Kocovský P.
PMID: 12916045
Angew Chem Int Ed Engl. 2003 Aug 11;42(31):3674-7. doi: 10.1002/anie.200351737.

No abstract available.

New Lewis-Acidic Molybdenum(II) and Tungsten(II) Catalysts for Intramolecular Carbonyl Ene and Prins Reactions. Reversal of the Stereoselectivity of Cyclization of Citronellal.

The Journal of organic chemistry

Kocovský P, Ahmed G, Srogl J, Malkov AV, Steele J.
PMID: 11674345
J Org Chem. 1999 Apr 16;64(8):2765-2775. doi: 10.1021/jo9821675.

New Mo(II) complexes BnEt(3)N(+)[Mo(CO)(4)ClBr(2)](-) (A) and Mo(CO)(5)(OTf)(2) (B) and their W(II) congeners D and E have been developed as catalysts for the title reactions. Unlike other Lewis acids, the latter catalysts exhibit cis-stereoselectivity in the cyclization of citronellal (1...

Bronchopulmonary infection due to Moraxella (Branhamella) catarrhalis at Qatif Central Hospital.

Annals of Saudi medicine

Elbashier AM, Al-Salem AH, Al-Jama AH, Khogali A, Abusrair H, Khot AP, Malik AG.
PMID: 17587050
Ann Saudi Med. 1992 Nov;12(6):562-4. doi: 10.5144/0256-4947.1992.562.

Moraxella (Branhamella) catarrhalis is now recognized as an important cause of respiratory tract infections. Over a two year period, Moraxella (Branhamella) catarrhalis was isolated in pure culture from 3.4% of the sputums collected from patients with symptoms of acute...

Desymmetrization of cyclic meso-epoxides with silicon tetrachloride catalyzed by PINDOX, a chiral bipyridine mono-N-oxide.

Organic letters

Malkov AV, Gordon MR, Stoncius S, Hussain J, Kocovský P.
PMID: 19899747
Org Lett. 2009 Dec 03;11(23):5390-3. doi: 10.1021/ol902148s.

PINDOX 8 has been identified as a chiral organocatalyst for the enantioselective ring-opening of cyclic meso-epoxides with SiCl(4) to produce chlorohydrins in up to 90% ee. The catalyst is most effective with saturated cyclic substrates containing more than seven...

Comparison of resonant tunneling in a double-quantum-well three-barrier system and a single-quantum-well double-barrier system.

Physical review. B, Condensed matter

Iogansen LV, Malov VV, Xu JM.
PMID: 10004722
Phys Rev B Condens Matter. 1993 Mar 15;47(12):7253-7259. doi: 10.1103/physrevb.47.7253.

No abstract available.

Kinetic Resolution of Secondary Allyl Boronates and Their Application in the Synthesis of Homoallylic Amines.

Chemistry (Weinheim an der Bergstrasse, Germany)

Villar L, Orlov NV, Kondratyev NS, Uria U, Vicario JL, Malkov AV.
PMID: 30175420
Chemistry. 2018 Nov 02;24(61):16262-16265. doi: 10.1002/chem.201804395. Epub 2018 Oct 09.

Highly enantioenriched, chromatographically-stable secondary allyl boronates featuring a 1,1,2,2-tetraethyl-1,2-ethanediol fragment (Epin) were obtained by kinetic resolution of their racemic mixtures. The Epin group at boron considerably improved stability of allyl boronates allowing them to be readily isolated by chromatography...

Increased paracellular permeability of tumor-adjacent areas in 1,2-dimethylhydrazine-induced colon carcinogenesis in rats.

Cancer biology & medicine

Bekusova VV, Falchuk EL, Okorokova LS, Kruglova NM, Nozdrachev AD, Markov AG.
PMID: 30197792
Cancer Biol Med. 2018 Aug;15(3):251-259. doi: 10.20892/j.issn.2095-3941.2018.0016.

OBJECTIVE: The morphology and functions of the proximal and distal large intestine are not the same. The incidence of colorectal cancer in these regions is also different, as tumors more often appear in the descending colon than in the...

Basolateral pressure challenges mammary epithelial cell monolayer integrity, in vitro.

Cytotechnology

Mießler KS, Vitzthum C, Markov AG, Amasheh S.
PMID: 28852895
Cytotechnology. 2018 Apr;70(2):567-576. doi: 10.1007/s10616-017-0130-3. Epub 2017 Aug 29.

Mammary gland epithelium is physiologically exposed to variations of hydrostatic pressure due to accumulation of milk and removal by suckling and mechanical milking. Integrity of the mammary gland epithelium primarily relies on the tight junction. To analyze pressure-induced effects...

Mechanistic dichotomy in the asymmetric allylation of aldehydes with allyltrichlorosilanes catalyzed by chiral pyridine N-oxides.

Chemistry (Weinheim an der Bergstrasse, Germany)

Malkov AV, Stončius S, Bell M, Castelluzzo F, Ramírez-López P, Biedermannová L, Langer V, Rulíšek L, Kočovský P.
PMID: 23744629
Chemistry. 2013 Jul 08;19(28):9167-85. doi: 10.1002/chem.201203817. Epub 2013 Jun 06.

Detailed kinetic and computational investigation of the enantio- and diastereoselective allylation of aldehydes 1 with allyltrichlorosilanes 5, employing the pyridine N-oxides METHOX (9) and QUINOX (10) as chiral organocatalysts, indicate that the reaction can proceed through a dissociative (cationic)...

Palladium-catalyzed stereoselective intramolecular oxidative amidation of alkenes in the synthesis of 1,3- and 1,4-amino alcohols and 1,3-diamines.

Chemistry (Weinheim an der Bergstrasse, Germany)

Malkov AV, Lee DS, Barłóg M, Elsegood MR, Kočovský P.
PMID: 24664814
Chemistry. 2014 Apr 22;20(17):4901-5. doi: 10.1002/chem.201400123. Epub 2014 Mar 24.

An efficient and practical Pd-catalyzed intramolecular oxidative allylic amidation provides facile access to derivatives of 1,3- and 1,4-amino alcohols and 1,3-diamines. The method operates under mild reaction conditions (RT) with molecular oxygen (1 atm) as the sole reoxidant of...

Early Pain Exposure Influences Functional Brain Connectivity in Very Preterm Neonates.

Frontiers in neuroscience

Tortora D, Severino M, Di Biase C, Malova M, Parodi A, Minghetti D, Traggiai C, Uccella S, Boeri L, Morana G, Rossi A, Ramenghi LA.
PMID: 31507370
Front Neurosci. 2019 Aug 23;13:899. doi: 10.3389/fnins.2019.00899. eCollection 2019.

BACKGROUND: Early exposure to nociceptive events may cause brain structural alterations in preterm neonates, with long-lasting consequences on neurodevelopmental outcome. Little is known on the extent to which early pain may affect brain connectivity. We aim to evaluate brain...

Showing 1 to 12 of 98 entries