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Showing 1 to 12 of 34 entries
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Improved survival in multiple myeloma during the 2005-2009 and 2010-2014 periods.

Leukemia

Corre J, Perrot A, Hulin C, Caillot D, Stoppa AM, Facon T, Leleu X, Dib M, Karlin L, Moreau P, Mohty M, Mariette C, Fontan J, Marolleau JP, Demarquette H, Slama B, Voillat L, Macro M, Orsini-Piocelle F, Brechignac S, Rey P, Collet P, Tiab M, Belhadj K, Lifermann F, Clement-Filliatre L, Sohn C, Richez V, Avet-Loiseau H.
PMID: 34099876
Leukemia. 2021 Dec;35(12):3600-3603. doi: 10.1038/s41375-021-01250-0. Epub 2021 Jun 07.

No abstract available.

Prognostic significance of concurrent gene mutations in intensively treated patients with IDH-mutated AML: an ALFA study.

Blood

Duchmann M, Micol JB, Duployez N, Raffoux E, Thomas X, Marolleau JP, Braun T, Adès L, Chantepie S, Lemasle E, Berthon C, Malfuson JV, Pautas C, Lambert J, Boissel N, Celli-Lebras K, Caillot D, Turlure P, Vey N, Pigneux A, Recher C, Terré C, Gardin C, Itzykson R, Preudhomme C, Dombret H, de Botton S.
PMID: 33881523
Blood. 2021 May 20;137(20):2827-2837. doi: 10.1182/blood.2020010165.

In patients with isocitrate dehydrogenase (IDH)-mutated acute myeloid leukemia (AML) treated by intensive chemotherapy (IC), prognostic significance of co-occurring genetic alterations and allogeneic hematopoietic stem cell transplantation (HSCT) are of particular interest with the advent of IDH1/2 mutant inhibitors....

Epidemiological landscape of young patients with multiple myeloma diagnosed before 40 years of age: the French experience.

Blood

Caulier A, Roussel M, Morel P, Lombion N, Branco B, Galtier J, Hulin C, Perrot A, Richez V, Michaud AV, Touzeau C, Doyen C, Mariette C, Caillot D, Harel S, Lenain P, Ivanoff S, Fontan J, Stoppa AM, Manier S, Garderet L, Leleu X, Marolleau JP, Arnulf B, Avet-Loiseau H, Royer B.
PMID: 34479366
Blood. 2021 Dec 23;138(25):2686-2695. doi: 10.1182/blood.2021011285.

Multiple myeloma (MM) is rare in young patients, especially before age 40 years at diagnosis, representing

Enhanced liver gene transfer and evasion of preexisting humoral immunity with exosome-enveloped AAV vectors.

Blood advances

Meliani A, Boisgerault F, Fitzpatrick Z, Marmier S, Leborgne C, Collaud F, Simon Sola M, Charles S, Ronzitti G, Vignaud A, van Wittenberghe L, Marolleau B, Jouen F, Tan S, Boyer O, Christophe O, Brisson AR, Maguire CA, Mingozzi F.
PMID: 29296848
Blood Adv. 2017 Oct 16;1(23):2019-2031. doi: 10.1182/bloodadvances.2017010181. eCollection 2017 Oct 24.

Results from clinical trials of liver gene transfer for hemophilia demonstrate the potential of the adeno-associated virus (AAV) vector platform. However, to achieve therapeutic transgene expression, in some cases high vector doses are required, which are associated with a...

Determination of monochloramine dissipation kinetics in various surface water qualities under relevant environmental conditions - Consequences regarding environmental risk assessment.

The Science of the total environment

Sacher F, Gerstner P, Merklinger M, Thoma A, Kinani A, Roumiguières A, Bouchonnet S, Richard-Tanaka B, Layousse S, Ata R, Marolleau F, Kinani S.
PMID: 31181531
Sci Total Environ. 2019 Oct 01;685:542-554. doi: 10.1016/j.scitotenv.2019.05.364. Epub 2019 May 24.

A total 190 experiments were performed to study the dissipation kinetics of monochloramine (NH

The Importance of an In-depth Study of Immunoglobulin Gene Rearrangements When Ascertaining the Clonal Relationship between Concomitant Chronic Lymphocytic Leukemia and Multiple Myeloma.

Frontiers in immunology

Trudel S, Ghamlouch H, Dremaux J, Delette C, Harrivel V, Marolleau JP, Gubler B.
PMID: 28082975
Front Immunol. 2016 Dec 27;7:625. doi: 10.3389/fimmu.2016.00625. eCollection 2016.

Chronic lymphocytic leukemia (CLL) and multiple myeloma (MM) are hematological disorders that occur at different stages of B-cell development. It has been shown that CLL B-cells can differentiate into plasma cells

Human Muscle Progenitor Cells Displayed Immunosuppressive Effect through Galectin-1 and Semaphorin-3A.

Stem cells international

Lecourt S, Lepelletier Y, Vanneaux V, Jarray R, Domet T, Raynaud F, Hadj-Slimane R, Cras A, Hermine O, Marolleau JP, Larghero J.
PMID: 22606205
Stem Cells Int. 2012;2012:412610. doi: 10.1155/2012/412610. Epub 2012 Apr 23.

In human skeletal muscle, myoblasts represent the main population of myogenic progenitors. We previously showed that, beside their myogenic differentiation capacities, myoblasts also differentiate towards osteogenic and chondrogenic lineages, some properties generally considered being hallmarks of mesenchymal stem cells...

Functional Validation of a New Alginate-based Hydrogel Scaffold Combined with Mesenchymal Stem Cells in a Rat Hard Palate Cleft Model.

Plastic and reconstructive surgery. Global open

Naudot M, Davrou J, Djebara AE, Barre A, Lavagen N, Lardière S, Azdad SZ, Zabijak L, Lack S, Devauchelle B, Marolleau JP, Le Ricousse S.
PMID: 32440413
Plast Reconstr Surg Glob Open. 2020 Apr 29;8(4):e2743. doi: 10.1097/GOX.0000000000002743. eCollection 2020 Apr.

BACKGROUND: One of the major difficulties in cleft palate repair is the requirement for several surgical procedures and autologous bone grafting to form a bony bridge across the cleft defect. Engineered tissue, composed of a biomaterial scaffold and multipotent...

Epidemiological landscape of young patients with multiple myeloma diagnosed before 40 years of age: the French experience.

Blood

Caulier A, Roussel M, Morel P, Lombion N, Branco B, Galtier J, Hulin C, Perrot A, Richez V, Michaud AV, Touzeau C, Doyen C, Mariette C, Caillot D, Harel S, Lenain P, Ivanoff S, Fontan J, Stoppa AM, Manier S, Garderet L, Leleu X, Marolleau JP, Arnulf B, Avet-Loiseau H, Royer B.
PMID: 34479366
Blood. 2021 Dec 23;138(25):2686-2695. doi: 10.1182/blood.2021011285.

Multiple myeloma (MM) is rare in young patients, especially before age 40 years at diagnosis, representing

Obinutuzumab plus lenalidomide (GALEN) in advanced, previously untreated follicular lymphoma in need of systemic therapy.

Blood

Bachy E, Houot R, Feugier P, Bouabdallah K, Bouabdallah R, Nicolas-Virelizier E, Maerevoet MMF, Fruchart C, Snauwaert S, Le Gouill S, Marolleau JP, Molina L, Moluçon Chabrot C, Thieblemont C, Tilly H, Bijou F, Haioun C, Van Den Neste EW, Fabiani B, Meignan M, Cartron G, Salles GA, Casasnovas RO, Morschhauser F.
PMID: 34936697
Blood. 2021 Dec 22; doi: 10.1182/blood.2021013526. Epub 2021 Dec 22.

Obinutuzumab and lenalidomide (GALEN) is an active immunomodulatory combination with a manageable safety profile in multiple types of lymphoma. We report efficacy and safety results for the phase 2 GALEN study in previously-untreated patients with advanced follicular lymphoma (FL)....

Hereditary Predisposition to Acute Myeloid Leukemia in Older Adults.

HemaSphere

Fenwarth L, Caulier A, Lachaier E, Goursaud L, Marceau-Renaut A, Fournier E, Lebon D, Boyer T, Berthon C, Marolleau JP, Preudhomme C, Duployez N.
PMID: 33778416
Hemasphere. 2021 Mar 23;5(4):e552. doi: 10.1097/HS9.0000000000000552. eCollection 2021 Apr.

No abstract available.

Molecular classification and prognosis in younger adults with acute myeloid leukemia and intermediate-risk cytogenetics treated or not by gemtuzumab ozogamycin: Final results of the GOELAMS/FILO acute myeloid leukemia 2006-intermediate-risk trial.

European journal of haematology

Bouvier A, Hamel JF, Delaunay J, Delabesse E, Dumas PY, Ledoux MP, Peterlin P, Luquet I, Roth Guepin G, Bulabois CE, Gallego Hernanz MP, Guillerm G, Guieze R, Hicheri Y, Simand C, Himberlin C, Hunault-Berger M, Bernard M, Jourdan E, Caillot D, Dorvaux V, Tavernier E, Daguindau E, Banos A, Ojeda-Uribe M, Gyan E, Alexis M, Marolleau JP, Turlure P, Bouscary D, Humbrecht C, Zerazhi H, Béné MC, Pigneux A, Carre M, Ifrah N, Blanchet O, Vey N, Récher C, Cornillet-Lefèbvre P.
PMID: 33765335
Eur J Haematol. 2021 Jul;107(1):111-121. doi: 10.1111/ejh.13626. Epub 2021 Apr 18.

In this randomized phase 3 study, the FILO group tested whether the addition of 6 mg/m

Showing 1 to 12 of 34 entries