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Showing 1 to 12 of 900 entries
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Microperimetric evaluation of chronic central serous chorioretinopathy after half-dose photodynamic therapy.

Clinical ophthalmology (Auckland, N.Z.)

Fujita K, Shinoda K, Matsumoto CS, Imamura Y, Tanaka E, Mizutani Y, Mizota A, Yuzawa M.
PMID: 23097612
Clin Ophthalmol. 2012;6:1681-7. doi: 10.2147/OPTH.S35338. Epub 2012 Oct 16.

BACKGROUND: The purpose of this study was to determine baseline clinical factors to correlate the outcome of half-dose verteporfin photodynamic therapy (PDT) in eyes with chronic central serous chorioretinopathy (CSC).METHODS: In this prospective, non-comparative, interventional case series, 14 eyes...

Intravenous immune globulin suppresses angiogenesis in mice and humans.

Signal transduction and targeted therapy

Yasuma R, Cicatiello V, Mizutani T, Tudisco L, Kim Y, Tarallo V, Bogdanovich S, Hirano Y, Kerur N, Li S, Yasuma T, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ambati BK, Helmers SB, Lundberg IE, Viklicky O, Leusen JH, Verbeek JS, Gelfand BD, Bastos-Carvalho A, De Falco S, Ambati J.
PMID: 26925256
Signal Transduct Target Ther. 2016;1. doi: 10.1038/sigtrans.2015.2. Epub 2016 Jan 28.

Human intravenous immune globulin (IVIg), a purified IgG fraction composed of ~ 60% IgG1 and obtained from the pooled plasma of thousands of donors, is clinically used for a wide range of diseases. The biological actions of IVIg are...

Graft versus host disease-dependent renal dysfunction after hematopoietic stem cell transplantation.

CEN case reports

Motoyoshi Y, Endo A, Takagi M, Morio T, Ito E, Nagata M, Mizutani S.
PMID: 28509199
CEN Case Rep. 2014 Nov;3(2):202-205. doi: 10.1007/s13730-014-0118-1. Epub 2014 Mar 21.

Nephropathy is an important complication in hematopoietic stem cell transplantation (HSCT) wherein multifactorial causes, i.e., radiation, drug toxicity, graft versus host disease (GVHD), are thought to contribute renal dysfunction. Here, we report a 10-year-old boy with high-risk acute myelocytic...

Practical Liposomal Formulation for Taxanes with Polyethoxylated Castor Oil and Ethanol with Complete Encapsulation Efficiency and High Loading Efficiency.

Nanomaterials (Basel, Switzerland)

Shigehiro T, Masuda J, Saito S, Khayrani AC, Jinno K, Seno A, Vaidyanath A, Mizutani A, Kasai T, Murakami H, Satoh A, Ito T, Hamada H, Seno Y, Mandai T, Seno M.
PMID: 28946623
Nanomaterials (Basel). 2017 Sep 23;7(10). doi: 10.3390/nano7100290.

Taxanes including paclitaxel and docetaxel are effective anticancer agents preferably sufficient for liposomal drug delivery. However, the encapsulation of these drugs with effective amounts into conventional liposomes is difficult due to their high hydrophobicity. Therefore, an effective encapsulation strategy...

Eosinophilic fasciitis associated with myositis.

Case reports in dermatology

Adachi Y, Mizutani Y, Shu E, Kanoh H, Miyazaki T, Seishima M.
PMID: 26034478
Case Rep Dermatol. 2015 Apr 30;7(1):79-83. doi: 10.1159/000381845. eCollection 2015.

Eosinophilic fasciitis is clinically characterized by symmetrical scleroderma-like indurations of the skin with pain. The histological features are fascial inflammation with lymphocytes and eosinophils as well as thickened and fibrotic fascia. Lymphocytic infiltration and degeneration of the underlying muscle...

Anthraquinone Production by Cell Suspension Cultures of Rubia akane Nakai.

Bioscience, biotechnology, and biochemistry

Mizutani H, Hashimoto O, Nakashima R, Nagai J.
PMID: 27393171
Biosci Biotechnol Biochem. 1997 Jan;61(10):1743-4. doi: 10.1271/bbb.61.1743.

The effects of various plant growth regulators and nutrients on cell growth and anthraquinone production in cell suspension cultures of Rubia akane Nakai were investigated. Use of an optimized medium resulted in a two-fold increase in the anthraquinone content....

Inhibiting Effects of Lunularic Acid Analogs on the Growth of Liverwort, Watercress, and Timothy Grass.

Bioscience, biotechnology, and biochemistry

Nakayama T, Fukushi Y, Mizutani J, Tahara S.
PMID: 27281146
Biosci Biotechnol Biochem. 1996 Jan;60(5):862-5. doi: 10.1271/bbb.60.862.

A number of analogs of lunularic acid varying in the number of methylene carbons between the two benzene rings and in the substituents on their rings were prepared, and their effects on the growth of liverwort gemmaling, watercress, and...

ATM Regulates Adipocyte Differentiation and Contributes to Glucose Homeostasis.

Cell reports

Takagi M, Uno H, Nishi R, Sugimoto M, Hasegawa S, Piao J, Ihara N, Kanai S, Kakei S, Tamura Y, Suganami T, Kamei Y, Shimizu T, Yasuda A, Ogawa Y, Mizutani S.
PMID: 25683718
Cell Rep. 2015 Feb 17;10(6):957-967. doi: 10.1016/j.celrep.2015.01.027. Epub 2015 Feb 12.

Ataxia-telangiectasia (A-T) patients occasionally develop diabetes mellitus. However, only limited attempts have been made to gain insight into the molecular mechanism of diabetes mellitus development in A-T patients. We found that Atm

Observed adducts on positive mode direct analysis in real time mass spectrometry - Proton/ammonium adduct selectivities of 600-sample in-house chemical library.

European journal of mass spectrometry (Chichester, England)

Sugimura N, Furuya A, Yatsu T, Igarashi Y, Aoyama R, Izutani C, Yamamoto Y, Shibue T.
PMID: 28657446
Eur J Mass Spectrom (Chichester). 2017 Feb;23(1):4-10. doi: 10.1177/1469066717693851. Epub 2017 Jan 01.

In this study, direct analysis in real time adduct selectivities of a 558 in-house high-resolution mass spectrometry sample library was evaluated. The protonated molecular ion ([M + H]

Noise reduction and signal-to-noise ratio improvement of atomic magnetometers with optical gradiometer configurations.

Optics express

Kamada K, Ito Y, Ichihara S, Mizutani N, Kobayashi T.
PMID: 25836917
Opt Express. 2015 Mar 09;23(5):6976-87. doi: 10.1364/OE.23.006976.

In the field of biomagnetic measurement, optically-pumped atomic magnetometers (OPAMs) have attracted significant attention. With the improvement of signal response and the reduction of sensor noise, the sensitivity of OPAMs is limited mainly by environmental magnetic noise. To reduce...

Electrical detection of millimeter-waves by magnetic tunnel junctions using perpendicular magnetized L10-FePd free layer.

Nano letters

Naganuma H, Kim G, Kawada Y, Inami N, Hatakeyama K, Iihama S, Nazrul Islam KM, Oogane M, Mizukami S, Ando Y.
PMID: 25549140
Nano Lett. 2015 Jan 14;15(1):623-8. doi: 10.1021/nl504114v. Epub 2015 Jan 02.

Spin dynamics excited by spin-polarized current in magnetic tunnel junctions (MTJs) is potentially useful in nanoscale electrical oscillation sources and detection devices. A spin oscillator/detector should work at a high frequency, such as that of a millimeter-wave, where the...

Ingestion of a moderate high-sucrose diet results in glucose intolerance with reduced liver glucokinase activity and impaired glucagon-like peptide-1 secretion.

Journal of diabetes investigation

Sakamoto E, Seino Y, Fukami A, Mizutani N, Tsunekawa S, Ishikawa K, Ogata H, Uenishi E, Kamiya H, Hamada Y, Sato H, Harada N, Toyoda Y, Miwa I, Nakamura J, Inagaki N, Oiso Y, Ozaki N.
PMID: 24843603
J Diabetes Investig. 2012 Oct 18;3(5):432-40. doi: 10.1111/j.2040-1124.2012.00208.x.

UNLABELLED: Aims/Introduction:  Excessive intake of sucrose can cause severe health issues, such as diabetes mellitus. In animal studies, consumption of a high-sucrose diet (SUC) has been shown to cause obesity, insulin resistance and glucose intolerance. However, several in vivo...

Showing 1 to 12 of 900 entries