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Microperimetric evaluation of chronic central serous chorioretinopathy after half-dose photodynamic therapy.

Clinical ophthalmology (Auckland, N.Z.)

Fujita K, Shinoda K, Matsumoto CS, Imamura Y, Tanaka E, Mizutani Y, Mizota A, Yuzawa M.
PMID: 23097612
Clin Ophthalmol. 2012;6:1681-7. doi: 10.2147/OPTH.S35338. Epub 2012 Oct 16.

BACKGROUND: The purpose of this study was to determine baseline clinical factors to correlate the outcome of half-dose verteporfin photodynamic therapy (PDT) in eyes with chronic central serous chorioretinopathy (CSC).METHODS: In this prospective, non-comparative, interventional case series, 14 eyes...

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Fujita K, Shinoda K, Matsumoto CS, et al. Microperimetric evaluation of chronic central serous chorioretinopathy after half-dose photodynamic therapy. Clin Ophthalmol. 2012;6:1681-7doi: 10.2147/OPTH.S35338.
Fujita, K., Shinoda, K., Matsumoto, C. S., Imamura, Y., Tanaka, E., Mizutani, Y., Mizota, A., & Yuzawa, M. (2012). Microperimetric evaluation of chronic central serous chorioretinopathy after half-dose photodynamic therapy. Clinical ophthalmology (Auckland, N.Z.), 61681-7. https://doi.org/10.2147/OPTH.S35338
Fujita, Kyoko, et al. "Microperimetric evaluation of chronic central serous chorioretinopathy after half-dose photodynamic therapy." Clinical ophthalmology (Auckland, N.Z.) vol. 6 (2012): 1681-7. doi: https://doi.org/10.2147/OPTH.S35338
Fujita K, Shinoda K, Matsumoto CS, Imamura Y, Tanaka E, Mizutani Y, Mizota A, Yuzawa M. Microperimetric evaluation of chronic central serous chorioretinopathy after half-dose photodynamic therapy. Clin Ophthalmol. 2012;6:1681-7. doi: 10.2147/OPTH.S35338. Epub 2012 Oct 16. PMID: 23097612; PMCID: PMC3476484.
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Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous Neoplasm.

Clinical and translational gastroenterology

Patra KC, Bardeesy N, Mizukami Y.
PMID: 28383565
Clin Transl Gastroenterol. 2017 Apr 06;8(4):e86. doi: 10.1038/ctg.2017.3.

Pancreatic ductal adenocarcinoma (PDA), one of the most lethal cancers worldwide, is associated with two main types of morphologically distinct precursors-pancreatic intraepithelial neoplasia (PanIN) and intraductal papillary mucinous neoplasm (IPMN). Although the progression of PanIN into invasive cancer has...

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Patra KC, Bardeesy N, Mizukami Y. Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous Neoplasm. Clin Transl Gastroenterol. 2017;8(4):e86doi: 10.1038/ctg.2017.3.
Patra, K. C., Bardeesy, N., & Mizukami, Y. (2017). Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous Neoplasm. Clinical and translational gastroenterology, 8(4), e86. https://doi.org/10.1038/ctg.2017.3
Patra, Krushna C, et al. "Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous Neoplasm." Clinical and translational gastroenterology vol. 8,4 (2017): e86. doi: https://doi.org/10.1038/ctg.2017.3
Patra KC, Bardeesy N, Mizukami Y. Diversity of Precursor Lesions For Pancreatic Cancer: The Genetics and Biology of Intraductal Papillary Mucinous Neoplasm. Clin Transl Gastroenterol. 2017 Apr 06;8(4):e86. doi: 10.1038/ctg.2017.3. PMID: 28383565; PMCID: PMC5415899.
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Intravenous immune globulin suppresses angiogenesis in mice and humans.

Signal transduction and targeted therapy

Yasuma R, Cicatiello V, Mizutani T, Tudisco L, Kim Y, Tarallo V, Bogdanovich S, Hirano Y, Kerur N, Li S, Yasuma T, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ambati BK, Helmers SB, Lundberg IE, Viklicky O, Leusen JH, Verbeek JS, Gelfand BD, Bastos-Carvalho A, De Falco S, Ambati J.
PMID: 26925256
Signal Transduct Target Ther. 2016;1. doi: 10.1038/sigtrans.2015.2. Epub 2016 Jan 28.

Human intravenous immune globulin (IVIg), a purified IgG fraction composed of ~ 60% IgG1 and obtained from the pooled plasma of thousands of donors, is clinically used for a wide range of diseases. The biological actions of IVIg are...

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Yasuma R, Cicatiello V, Mizutani T, et al. Intravenous immune globulin suppresses angiogenesis in mice and humans. Signal Transduct Target Ther. 2016;1doi: 10.1038/sigtrans.2015.2.
Yasuma, R., Cicatiello, V., Mizutani, T., Tudisco, L., Kim, Y., Tarallo, V., Bogdanovich, S., Hirano, Y., Kerur, N., Li, S., Yasuma, T., Fowler, B. J., Wright, C. B., Apicella, I., Greco, A., Brunetti, A., Ambati, B. K., Helmers, S. B., Lundberg, I. E., Viklicky, O., Leusen, J. H., Verbeek, J. S., Gelfand, B. D., Bastos-Carvalho, A., De Falco, S., & Ambati, J. (2016). Intravenous immune globulin suppresses angiogenesis in mice and humans. Signal transduction and targeted therapy, 1. https://doi.org/10.1038/sigtrans.2015.2
Yasuma, Reo, et al. "Intravenous immune globulin suppresses angiogenesis in mice and humans." Signal transduction and targeted therapy vol. 1 (2016). doi: https://doi.org/10.1038/sigtrans.2015.2
Yasuma R, Cicatiello V, Mizutani T, Tudisco L, Kim Y, Tarallo V, Bogdanovich S, Hirano Y, Kerur N, Li S, Yasuma T, Fowler BJ, Wright CB, Apicella I, Greco A, Brunetti A, Ambati BK, Helmers SB, Lundberg IE, Viklicky O, Leusen JH, Verbeek JS, Gelfand BD, Bastos-Carvalho A, De Falco S, Ambati J. Intravenous immune globulin suppresses angiogenesis in mice and humans. Signal Transduct Target Ther. 2016;1. doi: 10.1038/sigtrans.2015.2. Epub 2016 Jan 28. PMID: 26925256; PMCID: PMC4768485.
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Graft versus host disease-dependent renal dysfunction after hematopoietic stem cell transplantation.

CEN case reports

Motoyoshi Y, Endo A, Takagi M, Morio T, Ito E, Nagata M, Mizutani S.
PMID: 28509199
CEN Case Rep. 2014 Nov;3(2):202-205. doi: 10.1007/s13730-014-0118-1. Epub 2014 Mar 21.

Nephropathy is an important complication in hematopoietic stem cell transplantation (HSCT) wherein multifactorial causes, i.e., radiation, drug toxicity, graft versus host disease (GVHD), are thought to contribute renal dysfunction. Here, we report a 10-year-old boy with high-risk acute myelocytic...

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Motoyoshi Y, Endo A, Takagi M, et al. Graft versus host disease-dependent renal dysfunction after hematopoietic stem cell transplantation. CEN Case Rep. 2014;3(2):202-205doi: 10.1007/s13730-014-0118-1.
Motoyoshi, Y., Endo, A., Takagi, M., Morio, T., Ito, E., Nagata, M., & Mizutani, S. (2014). Graft versus host disease-dependent renal dysfunction after hematopoietic stem cell transplantation. CEN case reports, 3(2), 202-205. https://doi.org/10.1007/s13730-014-0118-1
Motoyoshi, Yaeko, et al. "Graft versus host disease-dependent renal dysfunction after hematopoietic stem cell transplantation." CEN case reports vol. 3,2 (2014): 202-205. doi: https://doi.org/10.1007/s13730-014-0118-1
Motoyoshi Y, Endo A, Takagi M, Morio T, Ito E, Nagata M, Mizutani S. Graft versus host disease-dependent renal dysfunction after hematopoietic stem cell transplantation. CEN Case Rep. 2014 Nov;3(2):202-205. doi: 10.1007/s13730-014-0118-1. Epub 2014 Mar 21. PMID: 28509199; PMCID: PMC5411568.
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Metastasis from a primary hepatic angiosarcoma to the colon: A case report and literature review.

Oncology letters

Mokutani Y, Hata T, Miyake Y, Kuroda H, Takahashi H, Haraguchi N, Nishimura J, Mizushima T, Yamamoto H, Doki Y, Mori M.
PMID: 28454464
Oncol Lett. 2017 Apr;13(4):2765-2769. doi: 10.3892/ol.2017.5755. Epub 2017 Feb 21.

Primary hepatic angiosarcoma is a rare type of tumor with a poor prognosis. To the best of our knowledge, curative surgery of a metastatic gastrointestinal angiosarcoma from a hepatic angiosarcoma has not been reported previously. In the present report,...

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Mokutani Y, Hata T, Miyake Y, et al. Metastasis from a primary hepatic angiosarcoma to the colon: A case report and literature review. Oncol Lett. 2017;13(4):2765-2769doi: 10.3892/ol.2017.5755.
Mokutani, Y., Hata, T., Miyake, Y., Kuroda, H., Takahashi, H., Haraguchi, N., Nishimura, J., Mizushima, T., Yamamoto, H., Doki, Y., & Mori, M. (2017). Metastasis from a primary hepatic angiosarcoma to the colon: A case report and literature review. Oncology letters, 13(4), 2765-2769. https://doi.org/10.3892/ol.2017.5755
Mokutani, Yukako, et al. "Metastasis from a primary hepatic angiosarcoma to the colon: A case report and literature review." Oncology letters vol. 13,4 (2017): 2765-2769. doi: https://doi.org/10.3892/ol.2017.5755
Mokutani Y, Hata T, Miyake Y, Kuroda H, Takahashi H, Haraguchi N, Nishimura J, Mizushima T, Yamamoto H, Doki Y, Mori M. Metastasis from a primary hepatic angiosarcoma to the colon: A case report and literature review. Oncol Lett. 2017 Apr;13(4):2765-2769. doi: 10.3892/ol.2017.5755. Epub 2017 Feb 21. PMID: 28454464; PMCID: PMC5403321.
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Practical Liposomal Formulation for Taxanes with Polyethoxylated Castor Oil and Ethanol with Complete Encapsulation Efficiency and High Loading Efficiency.

Nanomaterials (Basel, Switzerland)

Shigehiro T, Masuda J, Saito S, Khayrani AC, Jinno K, Seno A, Vaidyanath A, Mizutani A, Kasai T, Murakami H, Satoh A, Ito T, Hamada H, Seno Y, Mandai T, Seno M.
PMID: 28946623
Nanomaterials (Basel). 2017 Sep 23;7(10). doi: 10.3390/nano7100290.

Taxanes including paclitaxel and docetaxel are effective anticancer agents preferably sufficient for liposomal drug delivery. However, the encapsulation of these drugs with effective amounts into conventional liposomes is difficult due to their high hydrophobicity. Therefore, an effective encapsulation strategy...

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Shigehiro T, Masuda J, Saito S, et al. Practical Liposomal Formulation for Taxanes with Polyethoxylated Castor Oil and Ethanol with Complete Encapsulation Efficiency and High Loading Efficiency. Nanomaterials (Basel). 2017;7(10)doi: 10.3390/nano7100290.
Shigehiro, T., Masuda, J., Saito, S., Khayrani, A. C., Jinno, K., Seno, A., Vaidyanath, A., Mizutani, A., Kasai, T., Murakami, H., Satoh, A., Ito, T., Hamada, H., Seno, Y., Mandai, T., & Seno, M. (2017). Practical Liposomal Formulation for Taxanes with Polyethoxylated Castor Oil and Ethanol with Complete Encapsulation Efficiency and High Loading Efficiency. Nanomaterials (Basel, Switzerland), 7(10), . https://doi.org/10.3390/nano7100290
Shigehiro, Tsukasa, et al. "Practical Liposomal Formulation for Taxanes with Polyethoxylated Castor Oil and Ethanol with Complete Encapsulation Efficiency and High Loading Efficiency." Nanomaterials (Basel, Switzerland) vol. 7,10 (2017). doi: https://doi.org/10.3390/nano7100290
Shigehiro T, Masuda J, Saito S, Khayrani AC, Jinno K, Seno A, Vaidyanath A, Mizutani A, Kasai T, Murakami H, Satoh A, Ito T, Hamada H, Seno Y, Mandai T, Seno M. Practical Liposomal Formulation for Taxanes with Polyethoxylated Castor Oil and Ethanol with Complete Encapsulation Efficiency and High Loading Efficiency. Nanomaterials (Basel). 2017 Sep 23;7(10). doi: 10.3390/nano7100290. PMID: 28946623; PMCID: PMC5666455.
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Eosinophilic fasciitis associated with myositis.

Case reports in dermatology

Adachi Y, Mizutani Y, Shu E, Kanoh H, Miyazaki T, Seishima M.
PMID: 26034478
Case Rep Dermatol. 2015 Apr 30;7(1):79-83. doi: 10.1159/000381845. eCollection 2015.

Eosinophilic fasciitis is clinically characterized by symmetrical scleroderma-like indurations of the skin with pain. The histological features are fascial inflammation with lymphocytes and eosinophils as well as thickened and fibrotic fascia. Lymphocytic infiltration and degeneration of the underlying muscle...

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Adachi Y, Mizutani Y, Shu E, et al. Eosinophilic fasciitis associated with myositis. Case Rep Dermatol. 2015;7(1):79-83doi: 10.1159/000381845.
Adachi, Y., Mizutani, Y., Shu, E., Kanoh, H., Miyazaki, T., & Seishima, M. (2015). Eosinophilic fasciitis associated with myositis. Case reports in dermatology, 7(1), 79-83. https://doi.org/10.1159/000381845
Adachi, Yuko, et al. "Eosinophilic fasciitis associated with myositis." Case reports in dermatology vol. 7,1 (2015): 79-83. doi: https://doi.org/10.1159/000381845
Adachi Y, Mizutani Y, Shu E, Kanoh H, Miyazaki T, Seishima M. Eosinophilic fasciitis associated with myositis. Case Rep Dermatol. 2015 Apr 30;7(1):79-83. doi: 10.1159/000381845. eCollection 2015. PMID: 26034478; PMCID: PMC4448070.
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Anthraquinone Production by Cell Suspension Cultures of Rubia akane Nakai.

Bioscience, biotechnology, and biochemistry

Mizutani H, Hashimoto O, Nakashima R, Nagai J.
PMID: 27393171
Biosci Biotechnol Biochem. 1997 Jan;61(10):1743-4. doi: 10.1271/bbb.61.1743.

The effects of various plant growth regulators and nutrients on cell growth and anthraquinone production in cell suspension cultures of Rubia akane Nakai were investigated. Use of an optimized medium resulted in a two-fold increase in the anthraquinone content....

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Mizutani H, Hashimoto O, Nakashima R, et al. Anthraquinone Production by Cell Suspension Cultures of Rubia akane Nakai. Biosci Biotechnol Biochem. 1997;61(10):1743-4doi: 10.1271/bbb.61.1743.
Mizutani, H., Hashimoto, O., Nakashima, R., & Nagai, J. (1997). Anthraquinone Production by Cell Suspension Cultures of Rubia akane Nakai. Bioscience, biotechnology, and biochemistry, 61(10), 1743-4. https://doi.org/10.1271/bbb.61.1743
Mizutani, H, et al. "Anthraquinone Production by Cell Suspension Cultures of Rubia akane Nakai." Bioscience, biotechnology, and biochemistry vol. 61,10 (1997): 1743-4. doi: https://doi.org/10.1271/bbb.61.1743
Mizutani H, Hashimoto O, Nakashima R, Nagai J. Anthraquinone Production by Cell Suspension Cultures of Rubia akane Nakai. Biosci Biotechnol Biochem. 1997 Jan;61(10):1743-4. doi: 10.1271/bbb.61.1743. PMID: 27393171.
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Inhibiting Effects of Lunularic Acid Analogs on the Growth of Liverwort, Watercress, and Timothy Grass.

Bioscience, biotechnology, and biochemistry

Nakayama T, Fukushi Y, Mizutani J, Tahara S.
PMID: 27281146
Biosci Biotechnol Biochem. 1996 Jan;60(5):862-5. doi: 10.1271/bbb.60.862.

A number of analogs of lunularic acid varying in the number of methylene carbons between the two benzene rings and in the substituents on their rings were prepared, and their effects on the growth of liverwort gemmaling, watercress, and...

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Nakayama T, Fukushi Y, Mizutani J, et al. Inhibiting Effects of Lunularic Acid Analogs on the Growth of Liverwort, Watercress, and Timothy Grass. Biosci Biotechnol Biochem. 1996;60(5):862-5doi: 10.1271/bbb.60.862.
Nakayama, T., Fukushi, Y., Mizutani, J., & Tahara, S. (1996). Inhibiting Effects of Lunularic Acid Analogs on the Growth of Liverwort, Watercress, and Timothy Grass. Bioscience, biotechnology, and biochemistry, 60(5), 862-5. https://doi.org/10.1271/bbb.60.862
Nakayama, T, et al. "Inhibiting Effects of Lunularic Acid Analogs on the Growth of Liverwort, Watercress, and Timothy Grass." Bioscience, biotechnology, and biochemistry vol. 60,5 (1996): 862-5. doi: https://doi.org/10.1271/bbb.60.862
Nakayama T, Fukushi Y, Mizutani J, Tahara S. Inhibiting Effects of Lunularic Acid Analogs on the Growth of Liverwort, Watercress, and Timothy Grass. Biosci Biotechnol Biochem. 1996 Jan;60(5):862-5. doi: 10.1271/bbb.60.862. PMID: 27281146.
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Dome-shaped magnetic order competing with high-temperature superconductivity at high pressures in FeSe.

Nature communications

Sun JP, Matsuura K, Ye GZ, Mizukami Y, Shimozawa M, Matsubayashi K, Yamashita M, Watashige T, Kasahara S, Matsuda Y, Yan JQ, Sales BC, Uwatoko Y, Cheng JG, Shibauchi T.
PMID: 27431724
Nat Commun. 2016 Jul 19;7:12146. doi: 10.1038/ncomms12146.

The coexistence and competition between superconductivity and electronic orders, such as spin or charge density waves, have been a central issue in high transition-temperature (Tc) superconductors. Unlike other iron-based superconductors, FeSe exhibits nematic ordering without magnetism whose relationship with...

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Sun JP, Matsuura K, Ye GZ, et al. Dome-shaped magnetic order competing with high-temperature superconductivity at high pressures in FeSe. Nat Commun. 2016;7:12146doi: 10.1038/ncomms12146.
Sun, J. P., Matsuura, K., Ye, G. Z., Mizukami, Y., Shimozawa, M., Matsubayashi, K., Yamashita, M., Watashige, T., Kasahara, S., Matsuda, Y., Yan, J. Q., Sales, B. C., Uwatoko, Y., Cheng, J. G., & Shibauchi, T. (2016). Dome-shaped magnetic order competing with high-temperature superconductivity at high pressures in FeSe. Nature communications, 712146. https://doi.org/10.1038/ncomms12146
Sun, J P, et al. "Dome-shaped magnetic order competing with high-temperature superconductivity at high pressures in FeSe." Nature communications vol. 7 (2016): 12146. doi: https://doi.org/10.1038/ncomms12146
Sun JP, Matsuura K, Ye GZ, Mizukami Y, Shimozawa M, Matsubayashi K, Yamashita M, Watashige T, Kasahara S, Matsuda Y, Yan JQ, Sales BC, Uwatoko Y, Cheng JG, Shibauchi T. Dome-shaped magnetic order competing with high-temperature superconductivity at high pressures in FeSe. Nat Commun. 2016 Jul 19;7:12146. doi: 10.1038/ncomms12146. PMID: 27431724; PMCID: PMC4960320.
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ATM Regulates Adipocyte Differentiation and Contributes to Glucose Homeostasis.

Cell reports

Takagi M, Uno H, Nishi R, Sugimoto M, Hasegawa S, Piao J, Ihara N, Kanai S, Kakei S, Tamura Y, Suganami T, Kamei Y, Shimizu T, Yasuda A, Ogawa Y, Mizutani S.
PMID: 25683718
Cell Rep. 2015 Feb 17;10(6):957-967. doi: 10.1016/j.celrep.2015.01.027. Epub 2015 Feb 12.

Ataxia-telangiectasia (A-T) patients occasionally develop diabetes mellitus. However, only limited attempts have been made to gain insight into the molecular mechanism of diabetes mellitus development in A-T patients. We found that Atm

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Takagi M, Uno H, Nishi R, et al. ATM Regulates Adipocyte Differentiation and Contributes to Glucose Homeostasis. Cell Rep. 2015;10(6):957-967doi: 10.1016/j.celrep.2015.01.027.
Takagi, M., Uno, H., Nishi, R., Sugimoto, M., Hasegawa, S., Piao, J., Ihara, N., Kanai, S., Kakei, S., Tamura, Y., Suganami, T., Kamei, Y., Shimizu, T., Yasuda, A., Ogawa, Y., & Mizutani, S. (2015). ATM Regulates Adipocyte Differentiation and Contributes to Glucose Homeostasis. Cell reports, 10(6), 957-967. https://doi.org/10.1016/j.celrep.2015.01.027
Takagi, Masatoshi, et al. "ATM Regulates Adipocyte Differentiation and Contributes to Glucose Homeostasis." Cell reports vol. 10,6 (2015): 957-967. doi: https://doi.org/10.1016/j.celrep.2015.01.027
Takagi M, Uno H, Nishi R, Sugimoto M, Hasegawa S, Piao J, Ihara N, Kanai S, Kakei S, Tamura Y, Suganami T, Kamei Y, Shimizu T, Yasuda A, Ogawa Y, Mizutani S. ATM Regulates Adipocyte Differentiation and Contributes to Glucose Homeostasis. Cell Rep. 2015 Feb 17;10(6):957-967. doi: 10.1016/j.celrep.2015.01.027. Epub 2015 Feb 12. PMID: 25683718.
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Observed adducts on positive mode direct analysis in real time mass spectrometry - Proton/ammonium adduct selectivities of 600-sample in-house chemical library.

European journal of mass spectrometry (Chichester, England)

Sugimura N, Furuya A, Yatsu T, Igarashi Y, Aoyama R, Izutani C, Yamamoto Y, Shibue T.
PMID: 28657446
Eur J Mass Spectrom (Chichester). 2017 Feb;23(1):4-10. doi: 10.1177/1469066717693851. Epub 2017 Jan 01.

In this study, direct analysis in real time adduct selectivities of a 558 in-house high-resolution mass spectrometry sample library was evaluated. The protonated molecular ion ([M + H]

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Sugimura N, Furuya A, Yatsu T, et al. Observed adducts on positive mode direct analysis in real time mass spectrometry - Proton/ammonium adduct selectivities of 600-sample in-house chemical library. Eur J Mass Spectrom (Chichester). 2017;23(1):4-10doi: 10.1177/1469066717693851.
Sugimura, N., Furuya, A., Yatsu, T., Igarashi, Y., Aoyama, R., Izutani, C., Yamamoto, Y., & Shibue, T. (2017). Observed adducts on positive mode direct analysis in real time mass spectrometry - Proton/ammonium adduct selectivities of 600-sample in-house chemical library. European journal of mass spectrometry (Chichester, England), 23(1), 4-10. https://doi.org/10.1177/1469066717693851
Sugimura, Natsuhiko, et al. "Observed adducts on positive mode direct analysis in real time mass spectrometry - Proton/ammonium adduct selectivities of 600-sample in-house chemical library." European journal of mass spectrometry (Chichester, England) vol. 23,1 (2017): 4-10. doi: https://doi.org/10.1177/1469066717693851
Sugimura N, Furuya A, Yatsu T, Igarashi Y, Aoyama R, Izutani C, Yamamoto Y, Shibue T. Observed adducts on positive mode direct analysis in real time mass spectrometry - Proton/ammonium adduct selectivities of 600-sample in-house chemical library. Eur J Mass Spectrom (Chichester). 2017 Feb;23(1):4-10. doi: 10.1177/1469066717693851. Epub 2017 Jan 01. PMID: 28657446.
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