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Showing 1 to 12 of 124 entries
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Improvement of skeletal muscle performance in ageing by the metabolic modulator Trimetazidine.

Journal of cachexia, sarcopenia and muscle

Ferraro E, Pin F, Gorini S, Pontecorvo L, Ferri A, Mollace V, Costelli P, Rosano G.
PMID: 27239426
J Cachexia Sarcopenia Muscle. 2016 Sep;7(4):449-57. doi: 10.1002/jcsm.12097. Epub 2016 Jan 05.

BACKGROUND: The loss of muscle mass (sarcopenia) and the associated reduced muscle strength are key limiting factors for elderly people's quality of life. Improving muscle performance does not necessarily correlate with increasing muscle mass. In fact, particularly in the...

Decomposition of abnormal free locomotor behavior in a rat model of Parkinson's disease.

Frontiers in systems neuroscience

Grieb B, von Nicolai C, Engler G, Sharott A, Papageorgiou I, Hamel W, Engel AK, Moll CK.
PMID: 24348346
Front Syst Neurosci. 2013 Nov 27;7:95. doi: 10.3389/fnsys.2013.00095. eCollection 2013.

Poverty of spontaneous movement, slowed execution and reduced amplitudes of movement (akinesia, brady- and hypokinesia) are cardinal motor manifestations of Parkinson's disease that can be modeled in experimental animals by brain lesions affecting midbrain dopaminergic neurons. Most behavioral investigations...

Movement-Related Activity of Human Subthalamic Neurons during a Reach-to-Grasp Task.

Frontiers in human neuroscience

Pötter-Nerger M, Reese R, Steigerwald F, Heiden JA, Herzog J, Moll CKE, Hamel W, Ramirez-Pasos U, Falk D, Mehdorn M, Gerloff C, Deuschl G, Volkmann J.
PMID: 28936169
Front Hum Neurosci. 2017 Sep 07;11:436. doi: 10.3389/fnhum.2017.00436. eCollection 2017.

The aim of the study was to record movement-related single unit activity (SUA) in the human subthalamic nucleus (STN) during a standardized motor task of the upper limb. We performed microrecordings from the motor region of the human STN...

Child occupant protection: a summary of current safety recommendations.

Primary care update for Ob/Gyns

Arbogast KB, Moll EK, Morris SD, Winston FK.
PMID: 11435121
Prim Care Update Ob Gyns. 2001 Jul;8(4):141-148. doi: 10.1016/s1068-607x(01)00074-9.

In 1998, 140 children younger than 1 year of age were killed in motor vehicle crashes, and nearly half of those children killed were restrained. Used correctly, child safety seats dramatically reduce a child's risk of death in a...

Delivery of nanojoule femtosecond pulses through large-core microstructured fibers.

Optics letters

Ouzounov DG, Moll KD, Foster MA, Zipfel WR, Webb WW, Gaeta AL.
PMID: 18026490
Opt Lett. 2002 Sep 01;27(17):1513-5. doi: 10.1364/ol.27.001513.

We investigate femtosecond-pulse propagation through large-core microstructured fibers. Although these fibers are highly multimode, excitation of the fundamental mode is readily achieved, and coupling to higher-order modes is weak even when the fiber is bent or twisted. For prechirped...

Cavity-ringdown molecular spectroscopy based on an optical frequency comb at 1.45-1.65 microm.

Optics letters

Thorpe MJ, Hudson DD, Moll KD, Lasri J, Ye J.
PMID: 17215954
Opt Lett. 2007 Feb 01;32(3):307-9. doi: 10.1364/ol.32.000307.

Optical frequency comb-based cavity-ringdown spectroscopy has recently enabled high-sensitivity absorption detection of molecules over a broad spectral range. We demonstrate an improved system based on a mode-locked erbium-doped fiber laser source centered at 1.5 microm, resulting in a spectrometer...

Output coupling methods for cavity-based high-harmonic generation.

Optics express

Moll KD, Jones RJ, Ye J.
PMID: 19529192
Opt Express. 2006 Sep 04;14(18):8189-97. doi: 10.1364/oe.14.008189.

We have investigated the coupling efficiency and cavity loss associated with a ring cavity that has a hole in one of the focusing mirrors. The aperture provides a means through which intracavity high-harmonic generation can be coupled from the...

Efficient solution of Maxwell's equations for optical fibers with arbitrary refractive-index profiles.

Optics letters

Eoll CK, Goldring T, Lucas TR.
PMID: 19741891
Opt Lett. 1987 Oct 01;12(10):841-3. doi: 10.1364/ol.12.000841.

A straightforward method of solving vectorial wave equations in terms of electric fields for cylindrically symmetrical optical fibers is described. Input profiles are modeled by functions with continuous derivatives, so all fields are continuous. To iterate propagation constants, a...

Asymmetric pallidal neuronal activity in patients with cervical dystonia.

Frontiers in systems neuroscience

Moll CK, Galindo-Leon E, Sharott A, Gulberti A, Buhmann C, Koeppen JA, Biermann M, Bäumer T, Zittel S, Westphal M, Gerloff C, Hamel W, Münchau A, Engel AK.
PMID: 24574981
Front Syst Neurosci. 2014 Feb 11;8:15. doi: 10.3389/fnsys.2014.00015. eCollection 2014.

The origin of asymmetric clinical manifestation of symptoms in patients suffering from cervical dystonia (CD) is hitherto poorly understood. Dysregulated neuronal activity in the basal ganglia has been suggested to have a role in the pathophysiology of CD. Here,...

Triphenylphosphonioacetylide: A Species Isoelectronic with Isocyanides.

Angewandte Chemie (International ed. in English)

Bestmann HJ, Frank W, Moll C, Pohlschmidt A, Clark T, Göller A.
PMID: 29711265
Angew Chem Int Ed Engl. 1998 Feb 16;37(3):338-342. doi: 10.1002/(SICI)1521-3773(19980216)37:3<338::AID-ANIE338>3.0.CO;2-5.

Stabilized only by triphenylphosphane, the title compound 1 was synthesized and investigated theoretically (the HOMO of 1 is depicted on the right). Both calculations and experimental NMR spectra show that no Lewis structure can describe the geometry and charge...

Identification of a Potent Allosteric Inhibitor of Human Protein Kinase CK2 by Bacterial Surface Display Library Screening.

Pharmaceuticals (Basel, Switzerland)

Nienberg C, Garmann C, Gratz A, Bollacke A, Götz C, Jose J.
PMID: 28067769
Pharmaceuticals (Basel). 2017 Jan 05;10(1). doi: 10.3390/ph10010006.

Human protein kinase CK2 has emerged as promising target for the treatment of neoplastic diseases. The vast majority of kinase inhibitors known today target the ATP binding site, which is highly conserved among kinases and hence leads to limited...

Qualitative research in rehabilitation science: opportunities, challenges, and future directions.

Disability and rehabilitation

VanderKaay S, Moll SE, Gewurtz RE, Jindal P, Loyola-Sanchez A, Packham TL, Lim CY.
PMID: 27973927
Disabil Rehabil. 2018 Mar;40(6):705-713. doi: 10.1080/09638288.2016.1261414. Epub 2016 Dec 15.

PURPOSE: Qualitative research has had a significant impact within rehabilitation science over time. During the past 20 years the number of qualitative studies published per year in Disability and Rehabilitation has markedly increased (from 1 to 54). In addition,...

Showing 1 to 12 of 124 entries