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Showing 1 to 12 of 295 entries
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Timescales of mixing and of chemistry: general discussion.

Faraday discussions

Pope F, Monks PS, Kleffmann J, Tomlin A, Whalley L, Heard D, Rickard A, Bloss W, Harrison R, Madronich S, McFiggans G, Donahue NM, Molteni U, Wahner A, Brune W, Querol X, Hou S, Tong S, Kim S.
PMID: 27374206
Faraday Discuss. 2016 Jul 18;189:253-76. doi: 10.1039/C6FD90023B.

No abstract available.

PD-1 blockade at the time of tumor escape potentiates the immune-mediated antitumor effects of a melanoma-targeting monoclonal antibody.

Oncoimmunology

They L, Michaud HA, Becquart O, Lafont V, Guillot B, Boissière-Michot F, Jarlier M, Mollevi C, Eliaou JF, Bonnefoy N, Gros L.
PMID: 29123966
Oncoimmunology. 2017 Jul 20;6(10):e1353857. doi: 10.1080/2162402X.2017.1353857. eCollection 2017.

Tumor antigen-targeting monoclonal antibodies (TA-targeting mAbs) are used as therapeutics in many malignancies and their capacity to mobilize the host immunity puts them at the forefront of anti-cancer immunotherapies. Both innate and adaptive immune cells have been associated with...

Late Echocardiographic Study of Aortic Valve and Aortic Root after Surgery for Type A Acute Aortic Dissection.

Journal of cardiovascular echography

Molteni M, De Chiara B, Casadei F, Botta L, Merlanti B, Russo CF, Giannattasio C, Moreo A.
PMID: 28465967
J Cardiovasc Echogr. 2016 Jul-Sep;26(3):78-82. doi: 10.4103/2211-4122.187948.

OBJECTIVE: In case of concomitant aortic regurgitation (AR) valve, sparing operation is considered the first choice in selected patients. The aim of this retrospective clinical and echocardiographic study was to evaluate the long-term survival results of conservative approach and...

(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.

ACS medicinal chemistry letters

Choi HS, Rucker PV, Wang Z, Fan Y, Albaugh P, Chopiuk G, Gessier F, Sun F, Adrian F, Liu G, Hood T, Li N, Jia Y, Che J, McCormack S, Li A, Li J, Steffy A, Culazzo A, Tompkins C, Phung V, Kreusch A, Lu M, Hu B, Chaudhary A, Prashad M, Tuntland T, Liu B, Harris J, Seidel HM, Loren J, Molteni V.
PMID: 26005534
ACS Med Chem Lett. 2015 Mar 16;6(5):562-7. doi: 10.1021/acsmedchemlett.5b00050. eCollection 2015 May 14.

Deregulated kinase activities of tropomyosin receptor kinase (TRK) family members have been shown to be associated with tumorigenesis and poor prognosis in a variety of cancer types. In particular, several chromosomal rearrangements involving TRKA have been reported in colorectal,...

DFT-based quantitative prediction of regioselectivity: cycloaddition of nitrilimines to methyl propiolate.

The Journal of organic chemistry

Ponti A, Molteni G.
PMID: 11463282
J Org Chem. 2001 Jul 27;66(15):5252-5. doi: 10.1021/jo0156159.

No abstract available.

DFT-HSAB prediction of regioselectivity in 1,3-dipolar cycloadditions: behavior of (4-substituted)benzonitrile oxides towards methyl propiolate.

Chemistry (Weinheim an der Bergstrasse, Germany)

Ponti A, Molteni G.
PMID: 16259036
Chemistry. 2006 Jan 23;12(4):1156-61. doi: 10.1002/chem.200500739.

The regioselectivity of 1,3-dipolar cycloadditions between (4-substituted)benzonitrile oxides and methyl propiolate cannot be rationalized on the basis of the electron demand of the reactants or frontier molecular-orbital theory. To this problem, we have applied a quantitative formulation of the...

Clinical and functional examination of the spine in working communities: occurrence of alterations in the male control group.

Clinical biomechanics (Bristol, Avon)

Occhipinti E, Colombini D, Molteni G, Menoni O, Boccardi S, Grieco A.
PMID: 23915956
Clin Biomech (Bristol, Avon). 1989 Feb;4(1):25-33. doi: 10.1016/0268-0033(89)90064-8.

The paper reports the results obtained by applying a clinical method for the study of spinal disease as described elsewhere' in a control group of 200 male subjects, stratified for age, who had not been exposed to classically accepted...

Wearable monitoring devices for assistive technology: case studies in post-polio syndrome.

Sensors (Basel, Switzerland)

Andreoni G, Mazzola M, Perego P, Standoli CE, Manzoni S, Piccini L, Molteni F.
PMID: 24469354
Sensors (Basel). 2014 Jan 24;14(2):2012-27. doi: 10.3390/s140202012.

The correct choice and customization of an orthosis are crucial to obtain the best comfort and efficiency. This study explored the feasibility of a multivariate quantitative assessment of the functional efficiency of lower limb orthosis through a novel wearable...

The effect of using variable frequency trains during functional electrical stimulation cycling.

Neuromodulation : journal of the International Neuromodulation Society

Ferrante S, Schauer T, Ferrigno G, Raisch J, Molteni F.
PMID: 22151099
Neuromodulation. 2008 Jul;11(3):216-26. doi: 10.1111/j.1525-1403.2008.00169.x.

Objectives.  This paper describes an experimental investigation of variable frequency stimulation patterns as a means of increasing torque production and, hence, performance in cycling induced by functional electrical stimulation. Materials and Methods.  Experiments were conducted on six able-bodied subjects...

Effect of the serotonin transporter gene and of environment on the continuity of anxiety and depression traits throughout adolescence.

Epidemiology and psychiatric sciences

Nobile M, Greco A, Perna G, Colombo P, Bianchi V, Bellina M, Giorda R, Monzani D, Carlet O, Griez E, Molteni M.
PMID: 24148106
Epidemiol Psychiatr Sci. 2014 Dec;23(4):399-409. doi: 10.1017/S2045796013000565. Epub 2013 Oct 22.

Aims. Many studies of various stress reactive phenotypes suggest that 5-HTTLPR short allele carriers (S-carriers) are characterised by the stable trait of negative affectivity that is converted to psychopathology only under conditions of stress. In this study, we examined...

JMV5656, A Novel Derivative of TLQP-21, Triggers the Activation of a Calcium-Dependent Potassium Outward Current in Microglial Cells.

Frontiers in cellular neuroscience

Rivolta I, Binda A, Molteni L, Rizzi L, Bresciani E, Possenti R, Fehrentz JA, Verdié P, Martinez J, Omeljaniuk RJ, Locatelli V, Torsello A.
PMID: 28280458
Front Cell Neurosci. 2017 Feb 23;11:41. doi: 10.3389/fncel.2017.00041. eCollection 2017.

TLQP-21 (TLQPPASSRRRHFHHALPPAR) is a multifunctional peptide that is involved in the control of physiological functions, including feeding, reproduction, stress responsiveness, and general homeostasis. Despite the huge interest in TLQP-21 biological activity, very little is known about its intracellular mechanisms...

The Impact of Age-Related Macular Degeneration on Quality of Life and Its Association With Demographic Data: Results From the NEI VFQ-25 Questionnaire in a Norwegian Population.

Gerontology & geriatric medicine

Schippert AC, Jelin E, Moe MC, Heiberg T, Grov EK.
PMID: 30263908
Gerontol Geriatr Med. 2018 Sep 20;4:2333721418801601. doi: 10.1177/2333721418801601. eCollection 2018.

No abstract available.

Showing 1 to 12 of 295 entries