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Implementation research in mental health services: an emerging science with conceptual, methodological, and training challenges

Science interventions

Proctor EK, Aarons G.
GSID: e_CuI_dlqwEJ
EK Proctor, J Landsverk, G Aarons… - … and Policy in Mental …, 2009 - Springer

… and support, and various properties of interventions that make them more/less amenable to … ; system and organizational interventions from management science, economic, fiscal and … successful implementation of evidence-based interventions in varying service settings and …

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Proctor, E. K., Landsverk, J., Aarons, G., Chambers, D., Glisson, C., & Mittman, B. (2009). Implementation research in mental health services: an emerging science with conceptual, methodological, and training challenges. Administration and Policy in Mental Health and Mental Health Services Research, 36(1), 24-34.
Proctor, Enola K., et al. "Implementation research in mental health services: an emerging science with conceptual, methodological, and training challenges." Administration and Policy in Mental Health and Mental Health Services Research 36.1 (2009): 24-34.
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Organic compounds found near dump sites in Niagara Falls, New York.

Environmental science & technology

Elder VA, Proctor BL, Hites RA.
PMID: 22299705
Environ Sci Technol. 1981 Oct 01;15(10):1237-43. doi: 10.1021/es00092a015.

No abstract available.

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Elder VA, Proctor BL, Hites RA. Organic compounds found near dump sites in Niagara Falls, New York. Environ Sci Technol. 1981;15(10):1237-43doi: 10.1021/es00092a015.
Elder, V. A., Proctor, B. L., & Hites, R. A. (1981). Organic compounds found near dump sites in Niagara Falls, New York. Environmental science & technology, 15(10), 1237-43. https://doi.org/10.1021/es00092a015
Elder, V A, et al. "Organic compounds found near dump sites in Niagara Falls, New York." Environmental science & technology vol. 15,10 (1981): 1237-43. doi: https://doi.org/10.1021/es00092a015
Elder VA, Proctor BL, Hites RA. Organic compounds found near dump sites in Niagara Falls, New York. Environ Sci Technol. 1981 Oct 01;15(10):1237-43. doi: 10.1021/es00092a015. PMID: 22299705.
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Cu(I)-NHC catalyzed asymmetric silyl transfer to unsaturated lactams and amides.

Organic letters

Pace V, Rae JP, Procter DJ.
PMID: 24350760
Org Lett. 2014 Jan 17;16(2):476-9. doi: 10.1021/ol4033623. Epub 2013 Dec 18.

The first asymmetric silylation of unsaturated lactams and amides using Cu(I)-NHC catalysts and PhMe2SiBpin has been accomplished. The method has been exploited in an expedient asymmetric synthesis of the (R)-enantiomer of the nootropic drug oxiracetam.

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Pace V, Rae JP, Procter DJ. Cu(I)-NHC catalyzed asymmetric silyl transfer to unsaturated lactams and amides. Org Lett. 2013;16(2):476-9doi: 10.1021/ol4033623.
Pace, V., Rae, J. P., & Procter, D. J. (2014). Cu(I)-NHC catalyzed asymmetric silyl transfer to unsaturated lactams and amides. Organic letters, 16(2), 476-9. https://doi.org/10.1021/ol4033623
Pace, Vittorio, et al. "Cu(I)-NHC catalyzed asymmetric silyl transfer to unsaturated lactams and amides." Organic letters vol. 16,2 (2014): 476-9. doi: https://doi.org/10.1021/ol4033623
Pace V, Rae JP, Procter DJ. Cu(I)-NHC catalyzed asymmetric silyl transfer to unsaturated lactams and amides. Org Lett. 2014 Jan 17;16(2):476-9. doi: 10.1021/ol4033623. Epub 2013 Dec 18. PMID: 24350760.
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Enantioselective Generation of Adjacent Stereocenters in a Copper-Catalyzed Three-Component Coupling of Imines, Allenes, and Diboranes.

Angewandte Chemie (International ed. in English)

Yeung K, Ruscoe RE, Rae J, Pulis AP, Procter DJ.
PMID: 27539673
Angew Chem Int Ed Engl. 2016 Sep 19;55(39):11912-6. doi: 10.1002/anie.201606710. Epub 2016 Aug 19.

A highly enantio- and diastereoselective copper-catalyzed three-component coupling affords the first general synthesis of homoallylic amines bearing adjacent stereocenters from achiral starting materials. The method utilizes a commercially available NHC ligand and copper source, operates at ambient temperature, couples...

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Yeung K, Ruscoe RE, Rae J, et al. Enantioselective Generation of Adjacent Stereocenters in a Copper-Catalyzed Three-Component Coupling of Imines, Allenes, and Diboranes. Angew Chem Int Ed Engl. 2016;55(39):11912-6doi: 10.1002/anie.201606710.
Yeung, K., Ruscoe, R. E., Rae, J., Pulis, A. P., & Procter, D. J. (2016). Enantioselective Generation of Adjacent Stereocenters in a Copper-Catalyzed Three-Component Coupling of Imines, Allenes, and Diboranes. Angewandte Chemie (International ed. in English), 55(39), 11912-6. https://doi.org/10.1002/anie.201606710
Yeung, Kay, et al. "Enantioselective Generation of Adjacent Stereocenters in a Copper-Catalyzed Three-Component Coupling of Imines, Allenes, and Diboranes." Angewandte Chemie (International ed. in English) vol. 55,39 (2016): 11912-6. doi: https://doi.org/10.1002/anie.201606710
Yeung K, Ruscoe RE, Rae J, Pulis AP, Procter DJ. Enantioselective Generation of Adjacent Stereocenters in a Copper-Catalyzed Three-Component Coupling of Imines, Allenes, and Diboranes. Angew Chem Int Ed Engl. 2016 Sep 19;55(39):11912-6. doi: 10.1002/anie.201606710. Epub 2016 Aug 19. PMID: 27539673; PMCID: PMC5103189.
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Chemotherapeutic drug-specific alteration of microvascular blood flow in murine breast cancer as measured by diffuse correlation spectroscopy.

Biomedical optics express

Ramirez G, Proctor AR, Jung KW, Wu TT, Han S, Adams RR, Ren J, Byun DK, Madden KS, Brown EB, Foster TH, Farzam P, Durduran T, Choe R.
PMID: 27699124
Biomed Opt Express. 2016 Aug 24;7(9):3610-3630. doi: 10.1364/BOE.7.003610. eCollection 2016 Sep 01.

The non-invasive,

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Ramirez G, Proctor AR, Jung KW, et al. Chemotherapeutic drug-specific alteration of microvascular blood flow in murine breast cancer as measured by diffuse correlation spectroscopy. Biomed Opt Express. 2016;7(9):3610-3630doi: 10.1364/BOE.7.003610.
Ramirez, G., Proctor, A. R., Jung, K. W., Wu, T. T., Han, S., Adams, R. R., Ren, J., Byun, D. K., Madden, K. S., Brown, E. B., Foster, T. H., Farzam, P., Durduran, T., & Choe, R. (2016). Chemotherapeutic drug-specific alteration of microvascular blood flow in murine breast cancer as measured by diffuse correlation spectroscopy. Biomedical optics express, 7(9), 3610-3630. https://doi.org/10.1364/BOE.7.003610
Ramirez, Gabriel, et al. "Chemotherapeutic drug-specific alteration of microvascular blood flow in murine breast cancer as measured by diffuse correlation spectroscopy." Biomedical optics express vol. 7,9 (2016): 3610-3630. doi: https://doi.org/10.1364/BOE.7.003610
Ramirez G, Proctor AR, Jung KW, Wu TT, Han S, Adams RR, Ren J, Byun DK, Madden KS, Brown EB, Foster TH, Farzam P, Durduran T, Choe R. Chemotherapeutic drug-specific alteration of microvascular blood flow in murine breast cancer as measured by diffuse correlation spectroscopy. Biomed Opt Express. 2016 Aug 24;7(9):3610-3630. doi: 10.1364/BOE.7.003610. eCollection 2016 Sep 01. PMID: 27699124; PMCID: PMC5030036.
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Cu(I)-NHC-catalyzed silylation of allenes: diastereoselective three-component coupling with aldehydes.

Chemistry (Weinheim an der Bergstrasse, Germany)

Rae J, Hu YC, Procter DJ.
PMID: 25146221
Chemistry. 2014 Oct 06;20(41):13143-5. doi: 10.1002/chem.201404330. Epub 2014 Aug 21.

Copper-catalyzed silylation of aryl allenes using a silylborane reagent affords vinyl silane building blocks with high efficiency. The use of a seven-membered NHC ligand proved crucial for high regioselectivity. The catalytically generated allylcoppper intermediates were intercepted by aldehydes in...

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Rae J, Hu YC, Procter DJ. Cu(I)-NHC-catalyzed silylation of allenes: diastereoselective three-component coupling with aldehydes. Chemistry. 2014;20(41):13143-5doi: 10.1002/chem.201404330.
Rae, J., Hu, Y. C., & Procter, D. J. (2014). Cu(I)-NHC-catalyzed silylation of allenes: diastereoselective three-component coupling with aldehydes. Chemistry (Weinheim an der Bergstrasse, Germany), 20(41), 13143-5. https://doi.org/10.1002/chem.201404330
Rae, James, et al. "Cu(I)-NHC-catalyzed silylation of allenes: diastereoselective three-component coupling with aldehydes." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 20,41 (2014): 13143-5. doi: https://doi.org/10.1002/chem.201404330
Rae J, Hu YC, Procter DJ. Cu(I)-NHC-catalyzed silylation of allenes: diastereoselective three-component coupling with aldehydes. Chemistry. 2014 Oct 06;20(41):13143-5. doi: 10.1002/chem.201404330. Epub 2014 Aug 21. PMID: 25146221.
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Copper-Catalyzed Borylative Cross-Coupling of Allenes and Imines: Selective Three-Component Assembly of Branched Homoallyl Amines.

Angewandte Chemie (International ed. in English)

Rae J, Yeung K, McDouall JJ, Procter DJ.
PMID: 26632675
Angew Chem Int Ed Engl. 2016 Jan 18;55(3):1102-7. doi: 10.1002/anie.201508959. Epub 2015 Dec 03.

A copper-catalyzed three-component coupling of allenes, bis(pinacolato)diboron, and imines allows regio-, chemo-, and diastereoselective assembly of branched α,β-substituted-γ-boryl homoallylic amines, that is, products bearing versatile amino, alkenyl, and borane functionality. Alternatively, convenient oxidative workup allows access to α-substituted-β-amino ketones....

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Rae J, Yeung K, McDouall JJ, et al. Copper-Catalyzed Borylative Cross-Coupling of Allenes and Imines: Selective Three-Component Assembly of Branched Homoallyl Amines. Angew Chem Int Ed Engl. 2015;55(3):1102-7doi: 10.1002/anie.201508959.
Rae, J., Yeung, K., McDouall, J. J., & Procter, D. J. (2016). Copper-Catalyzed Borylative Cross-Coupling of Allenes and Imines: Selective Three-Component Assembly of Branched Homoallyl Amines. Angewandte Chemie (International ed. in English), 55(3), 1102-7. https://doi.org/10.1002/anie.201508959
Rae, James, et al. "Copper-Catalyzed Borylative Cross-Coupling of Allenes and Imines: Selective Three-Component Assembly of Branched Homoallyl Amines." Angewandte Chemie (International ed. in English) vol. 55,3 (2016): 1102-7. doi: https://doi.org/10.1002/anie.201508959
Rae J, Yeung K, McDouall JJ, Procter DJ. Copper-Catalyzed Borylative Cross-Coupling of Allenes and Imines: Selective Three-Component Assembly of Branched Homoallyl Amines. Angew Chem Int Ed Engl. 2016 Jan 18;55(3):1102-7. doi: 10.1002/anie.201508959. Epub 2015 Dec 03. PMID: 26632675; PMCID: PMC4736445.
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Cultural Adaptation and Implementation of Evidence-Based Parent-Training: A Systematic Review and Critique of Guiding Evidence.

Children and youth services review

Baumann AA, Powell BJ, Kohl PL, Tabak RG, Penalba V, Proctor EE, Domenech-Rodriguez MM, Cabassa LJ.
PMID: 25960585
Child Youth Serv Rev. 2015 Jun 01;53:113-120. doi: 10.1016/j.childyouth.2015.03.025.

With advances in knowledge regarding efficacious evidence-based interventions, there have been significant attempts to culturally adapt, implement, and disseminate parent training interventions broadly, especially across ethnic and cultural groups. We sought to examine the extent to which researchers and...

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Baumann AA, Powell BJ, Kohl PL, et al. Cultural Adaptation and Implementation of Evidence-Based Parent-Training: A Systematic Review and Critique of Guiding Evidence. Child Youth Serv Rev. 2015;53:113-120doi: 10.1016/j.childyouth.2015.03.025.
Baumann, A. A., Powell, B. J., Kohl, P. L., Tabak, R. G., Penalba, V., Proctor, E. E., Domenech-Rodriguez, M. M., & Cabassa, L. J. (2015). Cultural Adaptation and Implementation of Evidence-Based Parent-Training: A Systematic Review and Critique of Guiding Evidence. Children and youth services review, 53113-120. https://doi.org/10.1016/j.childyouth.2015.03.025
Baumann, Ana A, et al. "Cultural Adaptation and Implementation of Evidence-Based Parent-Training: A Systematic Review and Critique of Guiding Evidence." Children and youth services review vol. 53 (2015): 113-120. doi: https://doi.org/10.1016/j.childyouth.2015.03.025
Baumann AA, Powell BJ, Kohl PL, Tabak RG, Penalba V, Proctor EE, Domenech-Rodriguez MM, Cabassa LJ. Cultural Adaptation and Implementation of Evidence-Based Parent-Training: A Systematic Review and Critique of Guiding Evidence. Child Youth Serv Rev. 2015 Jun 01;53:113-120. doi: 10.1016/j.childyouth.2015.03.025. PMID: 25960585; PMCID: PMC4419735.
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Sulfoxide-Directed Metal-Free ortho-Propargylation of Aromatics and Heteroaromatics.

Chemistry (Weinheim an der Bergstrasse, Germany)

Eberhart AJ, Shrives HJ, Álvarez E, Carrër A, Zhang Y, Procter DJ.
PMID: 25832900
Chemistry. 2015 May 11;21(20):7313. doi: 10.1002/chem.201501070. Epub 2015 Apr 01.

No abstract available.

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Eberhart AJ, Shrives HJ, Álvarez E, et al. Sulfoxide-Directed Metal-Free ortho-Propargylation of Aromatics and Heteroaromatics. Chemistry. 2015;21(20):7313doi: 10.1002/chem.201501070.
Eberhart, A. J., Shrives, H. J., Álvarez, E., Carrër, A., Zhang, Y., & Procter, D. J. (2015). Sulfoxide-Directed Metal-Free ortho-Propargylation of Aromatics and Heteroaromatics. Chemistry (Weinheim an der Bergstrasse, Germany), 21(20), 7313. https://doi.org/10.1002/chem.201501070
Eberhart, Andrew J, et al. "Sulfoxide-Directed Metal-Free ortho-Propargylation of Aromatics and Heteroaromatics." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 21,20 (2015): 7313. doi: https://doi.org/10.1002/chem.201501070
Eberhart AJ, Shrives HJ, Álvarez E, Carrër A, Zhang Y, Procter DJ. Sulfoxide-Directed Metal-Free ortho-Propargylation of Aromatics and Heteroaromatics. Chemistry. 2015 May 11;21(20):7313. doi: 10.1002/chem.201501070. Epub 2015 Apr 01. PMID: 25832900.
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Rational Coupled Dynamics Network Manipulation Rescues Disease-Relevant Mutant Cystic Fibrosis Transmembrane Conductance Regulator.

Chemical science

Proctor EA, Kota P, Aleksandrov AA, He L, Riordan JR, Dokholyan NV.
PMID: 25685315
Chem Sci. 2015 Feb;6(2):1237-1246. doi: 10.1039/C4SC01320D.

Many cellular functions necessary for life are tightly regulated by protein allosteric conformational change, and correlated dynamics between protein regions has been found to contribute to the function of proteins not previously considered allosteric. The ability to map and...

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Proctor EA, Kota P, Aleksandrov AA, et al. Rational Coupled Dynamics Network Manipulation Rescues Disease-Relevant Mutant Cystic Fibrosis Transmembrane Conductance Regulator. Chem Sci. 2015;6(2):1237-1246doi: 10.1039/C4SC01320D.
Proctor, E. A., Kota, P., Aleksandrov, A. A., He, L., Riordan, J. R., & Dokholyan, N. V. (2015). Rational Coupled Dynamics Network Manipulation Rescues Disease-Relevant Mutant Cystic Fibrosis Transmembrane Conductance Regulator. Chemical science, 6(2), 1237-1246. https://doi.org/10.1039/C4SC01320D
Proctor, Elizabeth A, et al. "Rational Coupled Dynamics Network Manipulation Rescues Disease-Relevant Mutant Cystic Fibrosis Transmembrane Conductance Regulator." Chemical science vol. 6,2 (2015): 1237-1246. doi: https://doi.org/10.1039/C4SC01320D
Proctor EA, Kota P, Aleksandrov AA, He L, Riordan JR, Dokholyan NV. Rational Coupled Dynamics Network Manipulation Rescues Disease-Relevant Mutant Cystic Fibrosis Transmembrane Conductance Regulator. Chem Sci. 2015 Feb;6(2):1237-1246. doi: 10.1039/C4SC01320D. PMID: 25685315; PMCID: PMC4324596.
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Sulfoxide-Directed Metal-Free ortho-Propargylation of Aromatics and Heteroaromatics.

Chemistry (Weinheim an der Bergstrasse, Germany)

Eberhart AJ, Shrives HJ, Álvarez E, Carrër A, Zhang Y, Procter DJ.
PMID: 25752800
Chemistry. 2015 May 11;21(20):7428-34. doi: 10.1002/chem.201406424. Epub 2015 Mar 06.

A sulfoxide-directed, metal-free ortho-propargylation of aromatics and heteroaromatics exploits intermolecular delivery of a propargyl nucleophile to sulfur followed by an intramolecular relay to carbon. The operationally simple cross-coupling procedure is general, regiospecific with regard to the propargyl nucleophile, and...

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Eberhart AJ, Shrives HJ, Álvarez E, et al. Sulfoxide-Directed Metal-Free ortho-Propargylation of Aromatics and Heteroaromatics. Chemistry. 2015;21(20):7428-34doi: 10.1002/chem.201406424.
Eberhart, A. J., Shrives, H. J., Álvarez, E., Carrër, A., Zhang, Y., & Procter, D. J. (2015). Sulfoxide-Directed Metal-Free ortho-Propargylation of Aromatics and Heteroaromatics. Chemistry (Weinheim an der Bergstrasse, Germany), 21(20), 7428-34. https://doi.org/10.1002/chem.201406424
Eberhart, Andrew J, et al. "Sulfoxide-Directed Metal-Free ortho-Propargylation of Aromatics and Heteroaromatics." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 21,20 (2015): 7428-34. doi: https://doi.org/10.1002/chem.201406424
Eberhart AJ, Shrives HJ, Álvarez E, Carrër A, Zhang Y, Procter DJ. Sulfoxide-Directed Metal-Free ortho-Propargylation of Aromatics and Heteroaromatics. Chemistry. 2015 May 11;21(20):7428-34. doi: 10.1002/chem.201406424. Epub 2015 Mar 06. PMID: 25752800; PMCID: PMC4524421.
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Rotator cuff repair augmented with endogenous fibrin clot.

Arthroscopy techniques

Proctor CS.
PMID: 23766981
Arthrosc Tech. 2012 May 18;1(1):e79-82. doi: 10.1016/j.eats.2012.03.002. Print 2012 Sep.

Despite recent technical advances, rotator cuff repair continues to have a high retear rate. Recent research focused on biologic augmentation of rotator cuff repair with platelet-rich plasma has shown mixed results, and use of an endogenous fibrin clot from...

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Proctor CS. Rotator cuff repair augmented with endogenous fibrin clot. Arthrosc Tech. 2012;1(1):e79-82doi: 10.1016/j.eats.2012.03.002.
Proctor, C. S. (2012). Rotator cuff repair augmented with endogenous fibrin clot. Arthroscopy techniques, 1(1), e79-82. https://doi.org/10.1016/j.eats.2012.03.002
Proctor, Christopher S. "Rotator cuff repair augmented with endogenous fibrin clot." Arthroscopy techniques vol. 1,1 (2012): e79-82. doi: https://doi.org/10.1016/j.eats.2012.03.002
Proctor CS. Rotator cuff repair augmented with endogenous fibrin clot. Arthrosc Tech. 2012 May 18;1(1):e79-82. doi: 10.1016/j.eats.2012.03.002. Print 2012 Sep. PMID: 23766981; PMCID: PMC3678671.
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