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Showing 1 to 12 of 798 entries
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Organizational interventions employing principles of complexity science have improved outcomes for patients with Type II diabetes

Science interventions

Pugh J.
GSID: XUNL3cByFqAJ
LK Leykum, J Pugh, V Lawrence, M Parchman… - … Science, 2007 - Springer

… We hypothesize that interventions that leverage the characteristics of complex adaptive systems, intentionally or not, and regardless of the … of organizational interventions for patients with Type II diabetes and examine these interventions through the lens of complexity...

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Leykum, L. K., Pugh, J., Lawrence, V., Parchman, M., Noël, P. H., Cornell, J., & McDaniel, R. R. (2007). Organizational interventions employing principles of complexity science have improved outcomes for patients with Type II diabetes. Implementation Science, 2(1), 1-8.
Leykum, Luci K., et al. "Organizational interventions employing principles of complexity science have improved outcomes for patients with Type II diabetes." Implementation Science 2.1 (2007): 1-8.
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Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out Conformation.

ACS medicinal chemistry letters

Goodwin NC, Cianchetta G, Burgoon HA, Healy J, Mabon R, Strobel ED, Allen J, Wang S, Hamman BD, Rawlins DB.
PMID: 25589930
ACS Med Chem Lett. 2014 Aug 07;6(1):53-7. doi: 10.1021/ml500242y. eCollection 2015 Jan 08.

The first allosteric, type III inhibitor of LIM-kinase 2 (LIMK2) is reported. A series of molecules that feature both an N-phenylsulfonamide and tertiary amide were not only very potent at LIMK2 but also were extremely selective against a panel...

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Goodwin NC, Cianchetta G, Burgoon HA, et al. Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out Conformation. ACS Med Chem Lett. 2014;6(1):53-7doi: 10.1021/ml500242y.
Goodwin, N. C., Cianchetta, G., Burgoon, H. A., Healy, J., Mabon, R., Strobel, E. D., Allen, J., Wang, S., Hamman, B. D., & Rawlins, D. B. (2015). Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out Conformation. ACS medicinal chemistry letters, 6(1), 53-7. https://doi.org/10.1021/ml500242y
Goodwin, Nicole C, et al. "Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out Conformation." ACS medicinal chemistry letters vol. 6,1 (2015): 53-7. doi: https://doi.org/10.1021/ml500242y
Goodwin NC, Cianchetta G, Burgoon HA, Healy J, Mabon R, Strobel ED, Allen J, Wang S, Hamman BD, Rawlins DB. Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out Conformation. ACS Med Chem Lett. 2014 Aug 07;6(1):53-7. doi: 10.1021/ml500242y. eCollection 2015 Jan 08. PMID: 25589930; PMCID: PMC4291701.
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Bone density and its importance in orthodontics.

Journal of oral biology and craniofacial research

Chugh T, Jain AK, Jaiswal RK, Mehrotra P, Mehrotra R.
PMID: 25737892
J Oral Biol Craniofac Res. 2013 May-Aug;3(2):92-7. doi: 10.1016/j.jobcr.2013.01.001. Epub 2013 Jan 30.

BACKGROUND: Researchers have generally focused on tissue reactions occurring within the periodontal ligament and bone to find possible explanation for various clinical phenomena, with less attention being paid to the inherent bone density. Recently, regional differences in jaw anatomy...

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Chugh T, Jain AK, Jaiswal RK, et al. Bone density and its importance in orthodontics. J Oral Biol Craniofac Res. 2013;3(2):92-7doi: 10.1016/j.jobcr.2013.01.001.
Chugh, T., Jain, A. K., Jaiswal, R. K., Mehrotra, P., & Mehrotra, R. (2013). Bone density and its importance in orthodontics. Journal of oral biology and craniofacial research, 3(2), 92-7. https://doi.org/10.1016/j.jobcr.2013.01.001
Chugh, Tina, et al. "Bone density and its importance in orthodontics." Journal of oral biology and craniofacial research vol. 3,2 (2013): 92-7. doi: https://doi.org/10.1016/j.jobcr.2013.01.001
Chugh T, Jain AK, Jaiswal RK, Mehrotra P, Mehrotra R. Bone density and its importance in orthodontics. J Oral Biol Craniofac Res. 2013 May-Aug;3(2):92-7. doi: 10.1016/j.jobcr.2013.01.001. Epub 2013 Jan 30. PMID: 25737892; PMCID: PMC3942226.
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Oxocomplexes of U(vi) with 8-hydroxyquinoline-5-sulfonate in solution: structural studies and photophysical behaviour.

Dalton transactions (Cambridge, England : 2003)

Ramos ML, Justino LLG, Barata R, Costa T, Nogueira BA, Fausto R, Burrows HD.
PMID: 28548670
Dalton Trans. 2017 Jul 25;46(29):9358-9368. doi: 10.1039/c7dt01324h.

Multinuclear (

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Ramos ML, Justino LLG, Barata R, et al. Oxocomplexes of U(vi) with 8-hydroxyquinoline-5-sulfonate in solution: structural studies and photophysical behaviour. Dalton Trans. 2017;46(29):9358-9368doi: 10.1039/c7dt01324h.
Ramos, M. L., Justino, L. L. G., Barata, R., Costa, T., Nogueira, B. A., Fausto, R., & Burrows, H. D. (2017). Oxocomplexes of U(vi) with 8-hydroxyquinoline-5-sulfonate in solution: structural studies and photophysical behaviour. Dalton transactions (Cambridge, England : 2003), 46(29), 9358-9368. https://doi.org/10.1039/c7dt01324h
Ramos, M Luísa, et al. "Oxocomplexes of U(vi) with 8-hydroxyquinoline-5-sulfonate in solution: structural studies and photophysical behaviour." Dalton transactions (Cambridge, England : 2003) vol. 46,29 (2017): 9358-9368. doi: https://doi.org/10.1039/c7dt01324h
Ramos ML, Justino LLG, Barata R, Costa T, Nogueira BA, Fausto R, Burrows HD. Oxocomplexes of U(vi) with 8-hydroxyquinoline-5-sulfonate in solution: structural studies and photophysical behaviour. Dalton Trans. 2017 Jul 25;46(29):9358-9368. doi: 10.1039/c7dt01324h. PMID: 28548670.
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An Analysis of the Populations of the Air Force's Medical and Professional Officer Corps.

Rand health quarterly

Keating EG, Massey HG, Mele JD, Mundell BF.
PMID: 28083247
Rand Health Q. 2012 Jun 01;2(2):6. eCollection 2012.

Since the advent of the all-volunteer force, one of the foremost personnel challenges of the U.S. Air Force has been recruiting and retaining an adequate number of medical and professional officers in the Air Force's seven medical and professional...

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Keating EG, Massey HG, Mele JD, et al. An Analysis of the Populations of the Air Force's Medical and Professional Officer Corps. Rand Health Q. 2012;2(2):6
Keating, E. G., Massey, H. G., Mele, J. D., & Mundell, B. F. (2012). An Analysis of the Populations of the Air Force's Medical and Professional Officer Corps. Rand health quarterly, 2(2), 6.
Keating, Edward G, et al. "An Analysis of the Populations of the Air Force's Medical and Professional Officer Corps." Rand health quarterly vol. 2,2 (2012): 6.
Keating EG, Massey HG, Mele JD, Mundell BF. An Analysis of the Populations of the Air Force's Medical and Professional Officer Corps. Rand Health Q. 2012 Jun 01;2(2):6. eCollection 2012. PMID: 28083247; PMCID: PMC4945270.
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Ventilator-associated events … perhaps not the answer.

Journal of the Intensive Care Society

Pugh R, Harrison W, Battle C, Hancock C, Szakmany T.
PMID: 29118846
J Intensive Care Soc. 2017 Aug;18(3):263-264. doi: 10.1177/1751143717694917. Epub 2017 Jul 24.

No abstract available.

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Pugh R, Harrison W, Battle C, et al. Ventilator-associated events … perhaps not the answer. J Intensive Care Soc. 2017;18(3):263-264doi: 10.1177/1751143717694917.
Pugh, R., Harrison, W., Battle, C., Hancock, C., & Szakmany, T. (2017). Ventilator-associated events … perhaps not the answer. Journal of the Intensive Care Society, 18(3), 263-264. https://doi.org/10.1177/1751143717694917
Pugh, Richard, et al. "Ventilator-associated events … perhaps not the answer." Journal of the Intensive Care Society vol. 18,3 (2017): 263-264. doi: https://doi.org/10.1177/1751143717694917
Pugh R, Harrison W, Battle C, Hancock C, Szakmany T. Ventilator-associated events … perhaps not the answer. J Intensive Care Soc. 2017 Aug;18(3):263-264. doi: 10.1177/1751143717694917. Epub 2017 Jul 24. PMID: 29118846; PMCID: PMC5665133.
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Towards the Development of a Low-Cost Device for the Detection of Explosives Vapors by Fluorescence Quenching of Conjugated Polymers in Solid Matrices.

Sensors (Basel, Switzerland)

Martelo LM, das Neves TFP, Figueiredo J, Marques L, Fedorov A, Charas A, Berberan-Santos MN, Burrows HD.
PMID: 29099776
Sensors (Basel). 2017 Nov 03;17(11). doi: 10.3390/s17112532.

Conjugated polymers (CPs) have proved to be promising chemosensory materials for detecting nitroaromatic explosives vapors, as they quickly convert a chemical interaction into an easily-measured high-sensitivity optical output. The nitroaromatic analytes are strongly electron-deficient, whereas the conjugated polymer sensing...

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Martelo LM, das Neves TFP, Figueiredo J, et al. Towards the Development of a Low-Cost Device for the Detection of Explosives Vapors by Fluorescence Quenching of Conjugated Polymers in Solid Matrices. Sensors (Basel). 2017;17(11)doi: 10.3390/s17112532.
Martelo, L. M., das Neves, T. F. P., Figueiredo, J., Marques, L., Fedorov, A., Charas, A., Berberan-Santos, M. N., & Burrows, H. D. (2017). Towards the Development of a Low-Cost Device for the Detection of Explosives Vapors by Fluorescence Quenching of Conjugated Polymers in Solid Matrices. Sensors (Basel, Switzerland), 17(11), . https://doi.org/10.3390/s17112532
Martelo, Liliana M, et al. "Towards the Development of a Low-Cost Device for the Detection of Explosives Vapors by Fluorescence Quenching of Conjugated Polymers in Solid Matrices." Sensors (Basel, Switzerland) vol. 17,11 (2017). doi: https://doi.org/10.3390/s17112532
Martelo LM, das Neves TFP, Figueiredo J, Marques L, Fedorov A, Charas A, Berberan-Santos MN, Burrows HD. Towards the Development of a Low-Cost Device for the Detection of Explosives Vapors by Fluorescence Quenching of Conjugated Polymers in Solid Matrices. Sensors (Basel). 2017 Nov 03;17(11). doi: 10.3390/s17112532. PMID: 29099776; PMCID: PMC5712976.
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How do formative objective structured clinical examinations drive learning? Analysis of residents' perceptions.

Medical teacher

Pugh D, Desjardins I, Eva K.
PMID: 29037098
Med Teach. 2018 Jan;40(1):45-52. doi: 10.1080/0142159X.2017.1388502. Epub 2017 Oct 16.

INTRODUCTION: Although several studies have explored the relationship between learning and written tests, little is understood about how performance-based examinations influence learning. The purpose of this study was to explore how a formative objective structured clinical examination (OSCE) drives...

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Pugh D, Desjardins I, Eva K. How do formative objective structured clinical examinations drive learning? Analysis of residents' perceptions. Med Teach. 2017;40(1):45-52doi: 10.1080/0142159X.2017.1388502.
Pugh, D., Desjardins, I., & Eva, K. (2018). How do formative objective structured clinical examinations drive learning? Analysis of residents' perceptions. Medical teacher, 40(1), 45-52. https://doi.org/10.1080/0142159X.2017.1388502
Pugh, Debra, et al. "How do formative objective structured clinical examinations drive learning? Analysis of residents' perceptions." Medical teacher vol. 40,1 (2018): 45-52. doi: https://doi.org/10.1080/0142159X.2017.1388502
Pugh D, Desjardins I, Eva K. How do formative objective structured clinical examinations drive learning? Analysis of residents' perceptions. Med Teach. 2018 Jan;40(1):45-52. doi: 10.1080/0142159X.2017.1388502. Epub 2017 Oct 16. PMID: 29037098.
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The Ethics of Deep Brain Stimulation for the Treatment of Anorexia Nervosa.

Neuroethics

Maslen H, Pugh J, Savulescu J.
PMID: 26594256
Neuroethics. 2015;8(3):215-230. doi: 10.1007/s12152-015-9240-9. Epub 2015 Sep 24.

There is preliminary evidence, from case reports and investigational studies, to suggest that Deep Brain Stimulation (DBS) could be used to treat some patients with Anorexia Nervosa (AN). Although this research is at an early stage, the invasive nature...

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Maslen H, Pugh J, Savulescu J. The Ethics of Deep Brain Stimulation for the Treatment of Anorexia Nervosa. Neuroethics. 2015;8(3):215-230doi: 10.1007/s12152-015-9240-9.
Maslen, H., Pugh, J., & Savulescu, J. (2015). The Ethics of Deep Brain Stimulation for the Treatment of Anorexia Nervosa. Neuroethics, 8(3), 215-230. https://doi.org/10.1007/s12152-015-9240-9
Maslen, Hannah, et al. "The Ethics of Deep Brain Stimulation for the Treatment of Anorexia Nervosa." Neuroethics vol. 8,3 (2015): 215-230. doi: https://doi.org/10.1007/s12152-015-9240-9
Maslen H, Pugh J, Savulescu J. The Ethics of Deep Brain Stimulation for the Treatment of Anorexia Nervosa. Neuroethics. 2015;8(3):215-230. doi: 10.1007/s12152-015-9240-9. Epub 2015 Sep 24. PMID: 26594256; PMCID: PMC4643100.
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Drug abuse in paediatric dentistry: a cross-sectional study.

Journal of clinical and diagnostic research : JCDR

Sharma M, Tandon S, Chugh T, Sharma S, Ps P, Aggarwal V, Kashyap N.
PMID: 24783138
J Clin Diagn Res. 2014 Mar;8(3):205-7. doi: 10.7860/JCDR/2014/7134.4163. Epub 2014 Mar 15.

UNLABELLED: Compared to adult medicine, drug use in children is not extensively researched.OBJECTIVE: The objective of present study is to find out drug prescribing pattern in the Department of Pedodontics and Preventive Dentistry and Orthodontics in teaching hospitals in...

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Sharma M, Tandon S, Chugh T, et al. Drug abuse in paediatric dentistry: a cross-sectional study. J Clin Diagn Res. 2014;8(3):205-7doi: 10.7860/JCDR/2014/7134.4163.
Sharma, M., Tandon, S., Chugh, T., Sharma, S., Ps, P., Aggarwal, V., & Kashyap, N. (2014). Drug abuse in paediatric dentistry: a cross-sectional study. Journal of clinical and diagnostic research : JCDR, 8(3), 205-7. https://doi.org/10.7860/JCDR/2014/7134.4163
Sharma, Meenakshi, et al. "Drug abuse in paediatric dentistry: a cross-sectional study." Journal of clinical and diagnostic research : JCDR vol. 8,3 (2014): 205-7. doi: https://doi.org/10.7860/JCDR/2014/7134.4163
Sharma M, Tandon S, Chugh T, Sharma S, Ps P, Aggarwal V, Kashyap N. Drug abuse in paediatric dentistry: a cross-sectional study. J Clin Diagn Res. 2014 Mar;8(3):205-7. doi: 10.7860/JCDR/2014/7134.4163. Epub 2014 Mar 15. PMID: 24783138; PMCID: PMC4003644.
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A daily glass of red wine and lifestyle changes do not affect arterial blood pressure and heart rate in patients with carotid arteriosclerosis after 4 and 20 weeks.

Cerebrovascular diseases extra

Droste DW, Iliescu C, Vaillant M, Gantenbein M, De Bremaeker N, Lieunard C, Velez T, Meyer M, Guth T, Kuemmerle A, Chioti A.
PMID: 24403903
Cerebrovasc Dis Extra. 2013 Oct 05;3(1):121-9. doi: 10.1159/000354847. eCollection 2013.

BACKGROUND: Regular consumption of small amounts of red wine improves blood lipids. However, there is concern whether this beneficial effect might be counterbalanced by an increase in blood pressure (BP) and heart rate (HR), which are risk factors for...

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Droste DW, Iliescu C, Vaillant M, et al. A daily glass of red wine and lifestyle changes do not affect arterial blood pressure and heart rate in patients with carotid arteriosclerosis after 4 and 20 weeks. Cerebrovasc Dis Extra. 2013;3(1):121-9doi: 10.1159/000354847.
Droste, D. W., Iliescu, C., Vaillant, M., Gantenbein, M., De Bremaeker, N., Lieunard, C., Velez, T., Meyer, M., Guth, T., Kuemmerle, A., & Chioti, A. (2013). A daily glass of red wine and lifestyle changes do not affect arterial blood pressure and heart rate in patients with carotid arteriosclerosis after 4 and 20 weeks. Cerebrovascular diseases extra, 3(1), 121-9. https://doi.org/10.1159/000354847
Droste, Dirk W, et al. "A daily glass of red wine and lifestyle changes do not affect arterial blood pressure and heart rate in patients with carotid arteriosclerosis after 4 and 20 weeks." Cerebrovascular diseases extra vol. 3,1 (2013): 121-9. doi: https://doi.org/10.1159/000354847
Droste DW, Iliescu C, Vaillant M, Gantenbein M, De Bremaeker N, Lieunard C, Velez T, Meyer M, Guth T, Kuemmerle A, Chioti A. A daily glass of red wine and lifestyle changes do not affect arterial blood pressure and heart rate in patients with carotid arteriosclerosis after 4 and 20 weeks. Cerebrovasc Dis Extra. 2013 Oct 05;3(1):121-9. doi: 10.1159/000354847. eCollection 2013. PMID: 24403903; PMCID: PMC3884179.
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Pericellular Ca(2+) recycling potentiates thrombin-evoked Ca(2+) signals in human platelets.

Physiological reports

Sage SO, Pugh N, Farndale RW, Harper AG.
PMID: 24303163
Physiol Rep. 2013 Oct;1(5):e00085. doi: 10.1002/phy2.85. Epub 2013 Oct 11.

We have previously demonstrated that Na(+)/Ca(2+) exchangers (NCXs) potentiate Ca(2+) signaling evoked by thapsigargin in human platelets, via their ability to modulate the secretion of autocoids from dense granules. This link was confirmed in platelets stimulated with the physiological...

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Sage SO, Pugh N, Farndale RW, et al. Pericellular Ca(2+) recycling potentiates thrombin-evoked Ca(2+) signals in human platelets. Physiol Rep. 2013;1(5):e00085doi: 10.1002/phy2.85.
Sage, S. O., Pugh, N., Farndale, R. W., & Harper, A. G. (2013). Pericellular Ca(2+) recycling potentiates thrombin-evoked Ca(2+) signals in human platelets. Physiological reports, 1(5), e00085. https://doi.org/10.1002/phy2.85
Sage, Stewart O, et al. "Pericellular Ca(2+) recycling potentiates thrombin-evoked Ca(2+) signals in human platelets." Physiological reports vol. 1,5 (2013): e00085. doi: https://doi.org/10.1002/phy2.85
Sage SO, Pugh N, Farndale RW, Harper AG. Pericellular Ca(2+) recycling potentiates thrombin-evoked Ca(2+) signals in human platelets. Physiol Rep. 2013 Oct;1(5):e00085. doi: 10.1002/phy2.85. Epub 2013 Oct 11. PMID: 24303163; PMCID: PMC3841026.
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