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Teaching critical appraisal and application of medical literature to clinical problem-solving.

Journal of medical education

Radack KL, Valanis B.
PMID: 3959054
J Med Educ. 1986 Apr;61(4):329-31. doi: 10.1097/00001888-198604000-00011.

No abstract available.

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Radack KL, Valanis B. Teaching critical appraisal and application of medical literature to clinical problem-solving. J Med Educ. 1986;61(4):329-31doi: 10.1097/00001888-198604000-00011.
Radack, K. L., & Valanis, B. (1986). Teaching critical appraisal and application of medical literature to clinical problem-solving. Journal of medical education, 61(4), 329-31. https://doi.org/10.1097/00001888-198604000-00011
Radack, K L, and Valanis, B. "Teaching critical appraisal and application of medical literature to clinical problem-solving." Journal of medical education vol. 61,4 (1986): 329-31. doi: https://doi.org/10.1097/00001888-198604000-00011
Radack KL, Valanis B. Teaching critical appraisal and application of medical literature to clinical problem-solving. J Med Educ. 1986 Apr;61(4):329-31. doi: 10.1097/00001888-198604000-00011. PMID: 3959054.
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Precocious markers of cardiovascular risk and vascular damage in apparently healthy women with previous gestational diabetes.

Diabetology & metabolic syndrome

Zajdenverg L, Rodacki M, Faria JP, Pires ML, Oliveira JE, Halfoun VL.
PMID: 24955136
Diabetol Metab Syndr. 2014 May 26;6:63. doi: 10.1186/1758-5996-6-63. eCollection 2014.

UNLABELLED: Previous gestational diabetes mellitus (pGDM) indicates future risk for type 2 diabetes (T2DM). Insulin resistance (IR) may precede T2DM in many years and is associated with an increased risk for cardiovascular diseases.AIM: This study aims to identify endothelial...

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Zajdenverg L, Rodacki M, Faria JP, et al. Precocious markers of cardiovascular risk and vascular damage in apparently healthy women with previous gestational diabetes. Diabetol Metab Syndr. 2014;6:63doi: 10.1186/1758-5996-6-63.
Zajdenverg, L., Rodacki, M., Faria, J. P., Pires, M. L., Oliveira, J. E., & Halfoun, V. L. (2014). Precocious markers of cardiovascular risk and vascular damage in apparently healthy women with previous gestational diabetes. Diabetology & metabolic syndrome, 663. https://doi.org/10.1186/1758-5996-6-63
Zajdenverg, Lenita, et al. "Precocious markers of cardiovascular risk and vascular damage in apparently healthy women with previous gestational diabetes." Diabetology & metabolic syndrome vol. 6 (2014): 63. doi: https://doi.org/10.1186/1758-5996-6-63
Zajdenverg L, Rodacki M, Faria JP, Pires ML, Oliveira JE, Halfoun VL. Precocious markers of cardiovascular risk and vascular damage in apparently healthy women with previous gestational diabetes. Diabetol Metab Syndr. 2014 May 26;6:63. doi: 10.1186/1758-5996-6-63. eCollection 2014. PMID: 24955136; PMCID: PMC4064263.
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Analysis of negative result in serum anti-.

Journal of clinical biochemistry and nutrition

Adachi K, Mishiro T, Tanaka S, Kinoshita Y.
PMID: 27698543
J Clin Biochem Nutr. 2016 Sep;59(2):145-148. doi: 10.3164/jcbn.16-13. Epub 2016 Jun 10.

The purpose is to elucidate factors related to negative results of anti-

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Adachi K, Mishiro T, Tanaka S, et al. Analysis of negative result in serum anti-. J Clin Biochem Nutr. 2016;59(2):145-148doi: 10.3164/jcbn.16-13.
Adachi, K., Mishiro, T., Tanaka, S., & Kinoshita, Y. (2016). Analysis of negative result in serum anti-. Journal of clinical biochemistry and nutrition, 59(2), 145-148. https://doi.org/10.3164/jcbn.16-13
Adachi, Kyoichi, et al. "Analysis of negative result in serum anti-." Journal of clinical biochemistry and nutrition vol. 59,2 (2016): 145-148. doi: https://doi.org/10.3164/jcbn.16-13
Adachi K, Mishiro T, Tanaka S, Kinoshita Y. Analysis of negative result in serum anti-. J Clin Biochem Nutr. 2016 Sep;59(2):145-148. doi: 10.3164/jcbn.16-13. Epub 2016 Jun 10. PMID: 27698543; PMCID: PMC5018573.
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Small Molecules Facilitate Single Factor-Mediated Hepatic Reprogramming.

Cell reports

Lim KT, Lee SC, Gao Y, Kim KP, Song G, An SY, Adachi K, Jang YJ, Kim J, Oh KJ, Kwak TH, Hwang SI, You JS, Ko K, Koo SH, Sharma AD, Kim JH, Hui L, Cantz T, Schöler HR, Han DW.
PMID: 27149847
Cell Rep. 2016 Apr 26;15(4):814-829. doi: 10.1016/j.celrep.2016.03.071. Epub 2016 Apr 14.

Recent studies have shown that defined factors could lead to the direct conversion of fibroblasts into induced hepatocyte-like cells (iHeps). However, reported conversion efficiencies are very low, and the underlying mechanism of the direct hepatic reprogramming is largely unknown....

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Lim KT, Lee SC, Gao Y, et al. Small Molecules Facilitate Single Factor-Mediated Hepatic Reprogramming. Cell Rep. 2016;15(4):814-829doi: 10.1016/j.celrep.2016.03.071.
Lim, K. T., Lee, S. C., Gao, Y., Kim, K. P., Song, G., An, S. Y., Adachi, K., Jang, Y. J., Kim, J., Oh, K. J., Kwak, T. H., Hwang, S. I., You, J. S., Ko, K., Koo, S. H., Sharma, A. D., Kim, J. H., Hui, L., Cantz, T., Schöler, H. R., & Han, D. W. (2016). Small Molecules Facilitate Single Factor-Mediated Hepatic Reprogramming. Cell reports, 15(4), 814-829. https://doi.org/10.1016/j.celrep.2016.03.071
Lim, Kyung Tae, et al. "Small Molecules Facilitate Single Factor-Mediated Hepatic Reprogramming." Cell reports vol. 15,4 (2016): 814-829. doi: https://doi.org/10.1016/j.celrep.2016.03.071
Lim KT, Lee SC, Gao Y, Kim KP, Song G, An SY, Adachi K, Jang YJ, Kim J, Oh KJ, Kwak TH, Hwang SI, You JS, Ko K, Koo SH, Sharma AD, Kim JH, Hui L, Cantz T, Schöler HR, Han DW. Small Molecules Facilitate Single Factor-Mediated Hepatic Reprogramming. Cell Rep. 2016 Apr 26;15(4):814-829. doi: 10.1016/j.celrep.2016.03.071. Epub 2016 Apr 14. PMID: 27149847.
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Diagnostic utility of cardiac magnetic resonance for detection of cardiac involvement in female carriers of Duchenne muscular dystrophy.

Heart Asia

Iwase T, Takao S, Akaike M, Adachi K, Sumitomo-Ueda Y, Yagi S, Niki T, Kusunose K, Tomita N, Hirata Y, Yamaguchi K, Koshiba K, Taketani Y, Yamada H, Soeki T, Wakatsuki T, Aihara K, Harada M, Nishitani H, Sata M.
PMID: 27325943
Heart Asia. 2010 Jul 29;2(1):52-5. doi: 10.1136/ha.2010.002006. eCollection 2010.

BACKGROUND: Cardiac involvement is a recognised complication in female carriers of Duchenne muscular dystrophy (DMD). Since segmental or global left ventricle (LV) wall motion abnormalities in DMD carriers can arise even without apparent muscle weakness, it is difficult to...

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Iwase T, Takao S, Akaike M, et al. Diagnostic utility of cardiac magnetic resonance for detection of cardiac involvement in female carriers of Duchenne muscular dystrophy. Heart Asia. 2010;2(1):52-5doi: 10.1136/ha.2010.002006.
Iwase, T., Takao, S., Akaike, M., Adachi, K., Sumitomo-Ueda, Y., Yagi, S., Niki, T., Kusunose, K., Tomita, N., Hirata, Y., Yamaguchi, K., Koshiba, K., Taketani, Y., Yamada, H., Soeki, T., Wakatsuki, T., Aihara, K., Harada, M., Nishitani, H., & Sata, M. (2010). Diagnostic utility of cardiac magnetic resonance for detection of cardiac involvement in female carriers of Duchenne muscular dystrophy. Heart Asia, 2(1), 52-5. https://doi.org/10.1136/ha.2010.002006
Iwase, Takashi, et al. "Diagnostic utility of cardiac magnetic resonance for detection of cardiac involvement in female carriers of Duchenne muscular dystrophy." Heart Asia vol. 2,1 (2010): 52-5. doi: https://doi.org/10.1136/ha.2010.002006
Iwase T, Takao S, Akaike M, Adachi K, Sumitomo-Ueda Y, Yagi S, Niki T, Kusunose K, Tomita N, Hirata Y, Yamaguchi K, Koshiba K, Taketani Y, Yamada H, Soeki T, Wakatsuki T, Aihara K, Harada M, Nishitani H, Sata M. Diagnostic utility of cardiac magnetic resonance for detection of cardiac involvement in female carriers of Duchenne muscular dystrophy. Heart Asia. 2010 Jul 29;2(1):52-5. doi: 10.1136/ha.2010.002006. eCollection 2010. PMID: 27325943; PMCID: PMC4898527.
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Fundamental Differences between Group 8 Metals: Unexpected Oxidation State Preferences and Mechanisms in Ruthenium Borylene Complex Formation.

Chemistry (Weinheim an der Bergstrasse, Germany)

Braunschweig H, Damme A, Dewhurst RD, Radacki K, Weißenberger F, Wennemann B, Ye Q.
PMID: 27124888
Chemistry. 2016 Jun 13;22(25):8471-4. doi: 10.1002/chem.201601602. Epub 2016 May 09.

The reaction of the salts K[Ru(CO)3 (PMe3 )(SiR3 )] (R=Me, Et) with Br2 BDur or Cl2 BDur (Dur=2,3,5,6-Me4 C6 H) leads to both boryl and borylene complexes of divalent ruthenium, the former through simple salt elimination and the latter...

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Braunschweig H, Damme A, Dewhurst RD, et al. Fundamental Differences between Group 8 Metals: Unexpected Oxidation State Preferences and Mechanisms in Ruthenium Borylene Complex Formation. Chemistry. 2016;22(25):8471-4doi: 10.1002/chem.201601602.
Braunschweig, H., Damme, A., Dewhurst, R. D., Radacki, K., Weißenberger, F., Wennemann, B., & Ye, Q. (2016). Fundamental Differences between Group 8 Metals: Unexpected Oxidation State Preferences and Mechanisms in Ruthenium Borylene Complex Formation. Chemistry (Weinheim an der Bergstrasse, Germany), 22(25), 8471-4. https://doi.org/10.1002/chem.201601602
Braunschweig, Holger, et al. "Fundamental Differences between Group 8 Metals: Unexpected Oxidation State Preferences and Mechanisms in Ruthenium Borylene Complex Formation." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 22,25 (2016): 8471-4. doi: https://doi.org/10.1002/chem.201601602
Braunschweig H, Damme A, Dewhurst RD, Radacki K, Weißenberger F, Wennemann B, Ye Q. Fundamental Differences between Group 8 Metals: Unexpected Oxidation State Preferences and Mechanisms in Ruthenium Borylene Complex Formation. Chemistry. 2016 Jun 13;22(25):8471-4. doi: 10.1002/chem.201601602. Epub 2016 May 09. PMID: 27124888.
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Isolation of a neutral boron-containing radical stabilized by a cyclic (alkyl)(amino)carbene.

Angewandte Chemie (International ed. in English)

Bissinger P, Braunschweig H, Damme A, Krummenacher I, Phukan AK, Radacki K, Sugawara S.
PMID: 24917474
Angew Chem Int Ed Engl. 2014 Jul 07;53(28):7360-3. doi: 10.1002/anie.201403514. Epub 2014 Jun 10.

Utilizing a cyclic (alkyl)(amino)carbene (CAAC) as a ligand, neutral CAAC-stabilized radicals containing a boryl functionality could be prepared by reduction of the corresponding haloborane adducts. The radical species with a duryl substituent was fully characterized by single-crystal X-ray structural...

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Bissinger P, Braunschweig H, Damme A, et al. Isolation of a neutral boron-containing radical stabilized by a cyclic (alkyl)(amino)carbene. Angew Chem Int Ed Engl. 2014;53(28):7360-3doi: 10.1002/anie.201403514.
Bissinger, P., Braunschweig, H., Damme, A., Krummenacher, I., Phukan, A. K., Radacki, K., & Sugawara, S. (2014). Isolation of a neutral boron-containing radical stabilized by a cyclic (alkyl)(amino)carbene. Angewandte Chemie (International ed. in English), 53(28), 7360-3. https://doi.org/10.1002/anie.201403514
Bissinger, Philipp, et al. "Isolation of a neutral boron-containing radical stabilized by a cyclic (alkyl)(amino)carbene." Angewandte Chemie (International ed. in English) vol. 53,28 (2014): 7360-3. doi: https://doi.org/10.1002/anie.201403514
Bissinger P, Braunschweig H, Damme A, Krummenacher I, Phukan AK, Radacki K, Sugawara S. Isolation of a neutral boron-containing radical stabilized by a cyclic (alkyl)(amino)carbene. Angew Chem Int Ed Engl. 2014 Jul 07;53(28):7360-3. doi: 10.1002/anie.201403514. Epub 2014 Jun 10. PMID: 24917474.
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Insulin mediated improvement in glycemic control in elderly with type 2 diabetes mellitus can improve depressive symptoms and does not seem to impair health-related quality of life.

Diabetology & metabolic syndrome

Oliveira RA, Tostes M, Queiroz VA, Rodacki M, Zajdenverg L.
PMID: 26110026
Diabetol Metab Syndr. 2015 Jun 24;7:55. doi: 10.1186/s13098-015-0052-1. eCollection 2015.

BACKGROUND AND OBJECTIVES: Type 2 diabetes (T2D) is very prevalent among the elderly. Insulin therapy is often required for glycemic control. The association of starting this therapy with depressive symptoms as well the health-related quality of life (HRQoL) is...

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Oliveira RA, Tostes M, Queiroz VA, et al. Insulin mediated improvement in glycemic control in elderly with type 2 diabetes mellitus can improve depressive symptoms and does not seem to impair health-related quality of life. Diabetol Metab Syndr. 2015;7:55doi: 10.1186/s13098-015-0052-1.
Oliveira, R. A., Tostes, M., Queiroz, V. A., Rodacki, M., & Zajdenverg, L. (2015). Insulin mediated improvement in glycemic control in elderly with type 2 diabetes mellitus can improve depressive symptoms and does not seem to impair health-related quality of life. Diabetology & metabolic syndrome, 755. https://doi.org/10.1186/s13098-015-0052-1
Oliveira, R A, et al. "Insulin mediated improvement in glycemic control in elderly with type 2 diabetes mellitus can improve depressive symptoms and does not seem to impair health-related quality of life." Diabetology & metabolic syndrome vol. 7 (2015): 55. doi: https://doi.org/10.1186/s13098-015-0052-1
Oliveira RA, Tostes M, Queiroz VA, Rodacki M, Zajdenverg L. Insulin mediated improvement in glycemic control in elderly with type 2 diabetes mellitus can improve depressive symptoms and does not seem to impair health-related quality of life. Diabetol Metab Syndr. 2015 Jun 24;7:55. doi: 10.1186/s13098-015-0052-1. eCollection 2015. PMID: 26110026; PMCID: PMC4478689.
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Controlling Regiochemistry in the Syntheses of Boraindanes from Diborane(4) Starting Materials.

Chemistry (Weinheim an der Bergstrasse, Germany)

Arnold N, Braunschweig H, Ewing WC, Kupfer T, Radacki K, Thiess T, Trumpp A.
PMID: 27385314
Chemistry. 2016 Aug 01;22(32):11441-9. doi: 10.1002/chem.201601522. Epub 2016 Jul 07.

The reaction of tert-butylisonitrile (tBuNC) with 1,2-dihalo-1,2-diduryldiborane leads initially to the formation of the mono-base adduct of the symmetrical diborane(4), which then undergoes an intramolecular cyclization resulting in the formation of a 1-boraindane. This result is in contrast to...

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Arnold N, Braunschweig H, Ewing WC, et al. Controlling Regiochemistry in the Syntheses of Boraindanes from Diborane(4) Starting Materials. Chemistry. 2016;22(32):11441-9doi: 10.1002/chem.201601522.
Arnold, N., Braunschweig, H., Ewing, W. C., Kupfer, T., Radacki, K., Thiess, T., & Trumpp, A. (2016). Controlling Regiochemistry in the Syntheses of Boraindanes from Diborane(4) Starting Materials. Chemistry (Weinheim an der Bergstrasse, Germany), 22(32), 11441-9. https://doi.org/10.1002/chem.201601522
Arnold, Nicole, et al. "Controlling Regiochemistry in the Syntheses of Boraindanes from Diborane(4) Starting Materials." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 22,32 (2016): 11441-9. doi: https://doi.org/10.1002/chem.201601522
Arnold N, Braunschweig H, Ewing WC, Kupfer T, Radacki K, Thiess T, Trumpp A. Controlling Regiochemistry in the Syntheses of Boraindanes from Diborane(4) Starting Materials. Chemistry. 2016 Aug 01;22(32):11441-9. doi: 10.1002/chem.201601522. Epub 2016 Jul 07. PMID: 27385314.
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Marinibactrum halimedae gen. nov., sp. nov., a gammaproteobacterium isolated from a marine macroalga.

International journal of systematic and evolutionary microbiology

Nishijima M, Adachi K, Sano H, Yamasato K.
PMID: 28875922
Int J Syst Evol Microbiol. 2015 Nov;65(11):3866-3871. doi: 10.1099/ijsem.0.000502.

Phylogenetic and taxonomic characterization was performed for a bacterium, designated strain Q-192T, isolated from the surface of the green macroalga Halimeda sp., collected from the subtropical Ishigaki Island, Japan. The isolate was a polysaccharide-producing, Gram-stain-negative, aerobic, rod-shaped, motile bacterium...

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Nishijima M, Adachi K, Sano H, et al. Marinibactrum halimedae gen. nov., sp. nov., a gammaproteobacterium isolated from a marine macroalga. Int J Syst Evol Microbiol. 2015;65(11):3866-3871doi: 10.1099/ijsem.0.000502.
Nishijima, M., Adachi, K., Sano, H., & Yamasato, K. (2015). Marinibactrum halimedae gen. nov., sp. nov., a gammaproteobacterium isolated from a marine macroalga. International journal of systematic and evolutionary microbiology, 65(11), 3866-3871. https://doi.org/10.1099/ijsem.0.000502
Nishijima, Miyuki, et al. "Marinibactrum halimedae gen. nov., sp. nov., a gammaproteobacterium isolated from a marine macroalga." International journal of systematic and evolutionary microbiology vol. 65,11 (2015): 3866-3871. doi: https://doi.org/10.1099/ijsem.0.000502
Nishijima M, Adachi K, Sano H, Yamasato K. Marinibactrum halimedae gen. nov., sp. nov., a gammaproteobacterium isolated from a marine macroalga. Int J Syst Evol Microbiol. 2015 Nov;65(11):3866-3871. doi: 10.1099/ijsem.0.000502. PMID: 28875922.
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Global climate change driven by soot at the K-Pg boundary as the cause of the mass extinction.

Scientific reports

Kaiho K, Oshima N, Adachi K, Adachi Y, Mizukami T, Fujibayashi M, Saito R.
PMID: 27414998
Sci Rep. 2016 Jul 14;6:28427. doi: 10.1038/srep28427.

The mass extinction of life 66 million years ago at the Cretaceous/Paleogene boundary, marked by the extinctions of dinosaurs and shallow marine organisms, is important because it led to the macroevolution of mammals and appearance of humans. The current...

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Kaiho K, Oshima N, Adachi K, et al. Global climate change driven by soot at the K-Pg boundary as the cause of the mass extinction. Sci Rep. 2016;6:28427doi: 10.1038/srep28427.
Kaiho, K., Oshima, N., Adachi, K., Adachi, Y., Mizukami, T., Fujibayashi, M., & Saito, R. (2016). Global climate change driven by soot at the K-Pg boundary as the cause of the mass extinction. Scientific reports, 628427. https://doi.org/10.1038/srep28427
Kaiho, Kunio, et al. "Global climate change driven by soot at the K-Pg boundary as the cause of the mass extinction." Scientific reports vol. 6 (2016): 28427. doi: https://doi.org/10.1038/srep28427
Kaiho K, Oshima N, Adachi K, Adachi Y, Mizukami T, Fujibayashi M, Saito R. Global climate change driven by soot at the K-Pg boundary as the cause of the mass extinction. Sci Rep. 2016 Jul 14;6:28427. doi: 10.1038/srep28427. PMID: 27414998; PMCID: PMC4944614.
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Distribution of thyrotropin releasing hormone receptor in rats: an immunohistochemical study.

Endocrine regulations

Mitsuma T, Rhue N, Sobue G, Hirooka Y, Kayama M, Yokoi Y, Adachi K, Nogimori T, Sakai J, Sugie I.
PMID: 10993974
Endocr Regul. 1995 Sep;29(3):129-134.

Thyrotropin releasing hormone (TRH) receptor was identified immunohistochemically in the rat tissues using anti-peptide antiserum. Anti-TRH receptor antiserum was raised in New Zealand white rabbits immunized with a conjugate of synthetic TRH-receptor peptide (15-28) to bovine serum albumin. Immunohistochemical...

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Mitsuma T, Rhue N, Sobue G, et al. Distribution of thyrotropin releasing hormone receptor in rats: an immunohistochemical study. Endocr Regul. 1995;29(3):129-134
Mitsuma, T., Rhue, N., Sobue, G., Hirooka, Y., Kayama, M., Yokoi, Y., Adachi, K., Nogimori, T., Sakai, J., & Sugie, I. (1995). Distribution of thyrotropin releasing hormone receptor in rats: an immunohistochemical study. Endocrine regulations, 29(3), 129-134.
Mitsuma, et al. "Distribution of thyrotropin releasing hormone receptor in rats: an immunohistochemical study." Endocrine regulations vol. 29,3 (1995): 129-134.
Mitsuma T, Rhue N, Sobue G, Hirooka Y, Kayama M, Yokoi Y, Adachi K, Nogimori T, Sakai J, Sugie I. Distribution of thyrotropin releasing hormone receptor in rats: an immunohistochemical study. Endocr Regul. 1995 Sep;29(3):129-134. PMID: 10993974.
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