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Showing 1 to 12 of 171 entries
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IL-6 stimulates a concentration-dependent increase in MCP-1 in immortalised human brain endothelial cells.

F1000Research

Choi JM, Rotimi OO, O'Carroll SJ, Nicholson LF.
PMID: 27347374
F1000Res. 2016 Mar 03;5:270. doi: 10.12688/f1000research.8153.1. eCollection 2016.

Systemic inflammation is associated with neurodegeneration, with elevated interleukin-6 (IL-6) in particular being correlated with an increased risk of dementia. The brain endothelial cells of the blood brain barrier (BBB) serve as the interface between the systemic circulation and...

IL-6 stimulates a concentration-dependent increase in MCP-1 in immortalised human brain endothelial cells.

F1000Research

Choi JM, Rotimi OO, O'Carroll SJ, Nicholson LF.
PMID: 27347374
F1000Res. 2016 Mar 03;5:270. doi: 10.12688/f1000research.8153.2. eCollection 2016.

Systemic inflammation is associated with neurodegeneration, with elevated interleukin-6 (IL-6) in particular being correlated with an increased risk of dementia. The brain endothelial cells of the blood brain barrier (BBB) serve as the interface between the systemic circulation and...

Causative bacteria of respiratory tract infections in Kuwait by quantitative culture of sputum.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

Ahmed K, Wilson S, Jamal WY, Martinez G, Oishi K, Nagatake T, Rotimi VO.
PMID: 11810521
J Infect Chemother. 1999 Dec;5(4):217-219. doi: 10.1007/s101560050039.

To determine the bacterial etiology of lower respiratory tract infections in Kuwait, we performed quantitative culture of sputum and measured the susceptibilities of the isolated bacteria against different antibiotics. A total of 140 sputum samples were collected for a...

Selective catalytic oxidation of ammonia to nitrogen on atomic oxygen precovered Au(111).

Journal of the American Chemical Society

Gong J, Ojifinni RA, Kim TS, White JM, Mullins CB.
PMID: 16834356
J Am Chem Soc. 2006 Jul 19;128(28):9012-3. doi: 10.1021/ja062624w.

We demonstrate ammonia oxidation promoted by an atomic oxygen precovered Au(111) surface. The selectivity of the catalytic oxidation of ammonia to NO or N2 on Au(111) is tunable by the atomic oxygen coverage. We propose that N2 and NO...

Associations of adiponectin with individual European ancestry in African Americans: the Jackson Heart Study.

Frontiers in genetics

Bidulescu A, Choudhry S, Musani SK, Buxbaum SG, Liu J, Rotimi CN, Wilson JG, Taylor HA, Gibbons GH.
PMID: 24575123
Front Genet. 2014 Feb 10;5:22. doi: 10.3389/fgene.2014.00022. eCollection 2014.

BACKGROUND: Compared with European Americans, African Americans (AAs) exhibit lower levels of the cardio-metabolically protective adiponectin even after accounting for adiposity measures. Because few studies have examined in AA the association between adiponectin and genetic admixture, a dense panel...

What does genomic medicine mean for diverse populations?.

Molecular genetics & genomic medicine

Adeyemo A, Rotimi C.
PMID: 24498625
Mol Genet Genomic Med. 2014 Jan;2(1):3-6. doi: 10.1002/mgg3.63. Epub 2014 Jan 10.

No abstract available.

Circulating adiponectin is associated with renal function independent of age and serum lipids in west africans.

International journal of nephrology

Doumatey AP, Zhou J, Huang H, Adeleye J, Balogun W, Fasanmade O, Johnson T, Oli J, Okafor G, Amoah A, Eghan B, Agyenim-Boateng K, Acheampong J, Adebamowo C, Adeyemo A, Rotimi CN.
PMID: 22957255
Int J Nephrol. 2012;2012:730920. doi: 10.1155/2012/730920. Epub 2012 Aug 22.

Adiponectin, a protein secreted by adipose tissue, has been associated with renal dysfunction. However, these observations have not been adequately investigated in large epidemiological studies of healthy individuals in general and in African populations in particular. Hence, we designed...

Peculiarities and management challenges of advanced renal cell carcinoma incidentally discovered in pregnancy.

Clinical case reports

David RA, Idowu B, Akindiose C, Laoye A, Aluko JA, Omisore AD, Alajiki E, Komolafe AO, Salako AA, Onwudiegwu U.
PMID: 29744074
Clin Case Rep. 2018 Mar 12;6(5):863-866. doi: 10.1002/ccr3.1485. eCollection 2018 May.

Our aim is that urologists, gynecologists, nephrologists, and general practitioners will be reminded that diagnosis of renal malignancies sometimes require a high index of suspicion as they may remain asymptomatic in advanced stages; even as they can also rarely...

Genome-wide association study for proliferative diabetic retinopathy in Africans.

NPJ genomic medicine

Liu C, Chen G, Bentley AR, Doumatey A, Zhou J, Adeyemo A, Yang J, Rotimi C.
PMID: 31482010
NPJ Genom Med. 2019 Aug 29;4:20. doi: 10.1038/s41525-019-0094-7. eCollection 2019.

Proliferative diabetic retinopathy (PDR) is a sight-threatening complication of diabetes that is associated with longer duration of diabetes and poor glycemic control under a genetic susceptibility background. Although GWAS of PDR have been conducted in Europeans and Asians, none...

High prevalence of irritable bowel syndrome-type symptoms in microscopic colitis: implications for treatment.

Therapeutic advances in gastroenterology

Kane JS, Irvine AJ, Derwa Y, Rotimi O, Ford AC.
PMID: 29977339
Therap Adv Gastroenterol. 2018 Jun 21;11:1756284818783600. doi: 10.1177/1756284818783600. eCollection 2018.

BACKGROUND: Patients with microscopic colitis (MC) often present with abdominal pain and diarrhoea, and previous data suggest that there may be overlap between MC and irritable bowel syndrome (IBS). We evaluated the prevalence of IBS-type symptoms in patients with...

Evaluating the promise of inclusion of African ancestry populations in genomics.

NPJ genomic medicine

Bentley AR, Callier SL, Rotimi CN.
PMID: 32140257
NPJ Genom Med. 2020 Feb 25;5:5. doi: 10.1038/s41525-019-0111-x. eCollection 2020.

The lack of representation of diverse ancestral backgrounds in genomic research is well-known, and the resultant scientific and ethical limitations are becoming increasingly appreciated. The paucity of data on individuals with African ancestry is especially noteworthy as Africa is...

Correction: Genetic associations between serum low LDL-cholesterol levels and variants in LDLR, APOB, PCSK9 and LDLRAP1 in African populations.

PloS one

Hayat M, Kerr R, Bentley AR, Rotimi CN, Raal FJ, Ramsay M.
PMID: 33770136
PLoS One. 2021 Mar 26;16(3):e0249478. doi: 10.1371/journal.pone.0249478. eCollection 2021.

[This corrects the article DOI: 10.1371/journal.pone.0229098.].

Showing 1 to 12 of 171 entries