Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 1840 entries
Sorted by: Best Match Show Resources per page
Population pharmacokinetics of olprinone in healthy male volunteers.

Clinical pharmacology : advances and applications

Kunisawa T, Kasai H, Suda M, Yoshimura M, Sugawara A, Izumi Y, Iida T, Kurosawa A, Iwasaki H.
PMID: 24623995
Clin Pharmacol. 2014 Mar 04;6:43-50. doi: 10.2147/CPAA.S50626. eCollection 2014.

BACKGROUND: Olprinone decreases the cardiac preload and/or afterload because of its vasodilatory effect and increases myocardial contractility by inhibiting phosphodiesterase III.PURPOSE: The objective of this study was to characterize the population pharmacokinetics of olprinone after a single continuous infusion...

Structural characterization of copia-type retrotransposons leads to insights into the marker development in a biofuel crop, Jatropha curcas L.

Biotechnology for biofuels

Alipour A, Tsuchimoto S, Sakai H, Ohmido N, Fukui K.
PMID: 24020916
Biotechnol Biofuels. 2013 Sep 10;6(1):129. doi: 10.1186/1754-6834-6-129.

BACKGROUND: Recently, Jatropha curcas L. has attracted worldwide attention for its potential as a source of biodiesel. However, most DNA markers have demonstrated high levels of genetic similarity among and within jatropha populations around the globe. Despite promising features...

Effects of irbesartan on serum uric acid levels in patients with hypertension and diabetes.

Clinical pharmacology : advances and applications

Nakamura M, Sasai N, Hisatome I, Ichida K.
PMID: 24833923
Clin Pharmacol. 2014 May 03;6:79-86. doi: 10.2147/CPAA.S61462. eCollection 2014.

BACKGROUND: Hyperuricemia has been proposed to be a risk factor for cardiovascular disease and chronic kidney disease. Since diabetes is often complicated by hypertension and hyperuricemia, efficient therapeutic strategy against these two complications is very important in diabetic treatment....

Retinoid roles in blocking hepatocellular carcinoma.

Hepatobiliary surgery and nutrition

Shirakami Y, Sakai H, Shimizu M.
PMID: 26311412
Hepatobiliary Surg Nutr. 2015 Aug;4(4):222-8. doi: 10.3978/j.issn.2304-3881.2015.05.01.

Hepatocellular carcinoma (HCC) is a major health issue in many countries. The prognosis of HCC is still poor due to its high recurrence rate and its resistance to chemotherapy. Retinoids have long been known to have a connection with...

Magnetocaloric Materials with Multiple Instabilities.

Advanced materials (Deerfield Beach, Fla.)

Taguchi Y, Sakai H, Choudhury D.
PMID: 28387437
Adv Mater. 2017 Jul;29(25). doi: 10.1002/adma.201606144. Epub 2017 Apr 07.

The magnetocaloric effect is a well-known phenomenon where the temperature of a magnetic material varies upon application or removal of a magnetic field. This effect is anticipated to be applied to magnetic refrigeration technology, which is environmentally benign. For...

Rationale and design of ASSAF-K (A study of the safety and efficacy of anticoagulant therapy in the treatment of atrial fibrillation in Kanagawa).

Journal of arrhythmia

Hatori Y, Sakai H, Kunishima T, Hatori N, Chen L, Ishigami T, Satoh N.
PMID: 28416976
J Arrhythm. 2017 Apr;33(2):111-116. doi: 10.1016/j.joa.2016.07.008. Epub 2016 Aug 23.

BACKGROUND: Atrial fibrillation (AF) is one of the most prevalent cardiac arrhythmias associated with substantially increased risks of ischemic stroke and thromboembolism. Oral anticoagulants (OACs) are the cornerstone of AF management and effectively prevent AF-related stroke. As new non-vitamin...

Diagnosing and discriminating between primary and secondary aneurysmal bone cysts.

Oncology letters

Sasaki H, Nagano S, Shimada H, Yokouchi M, Setoguchi T, Ishidou Y, Kunigou O, Maehara K, Komiya S.
PMID: 28454393
Oncol Lett. 2017 Apr;13(4):2290-2296. doi: 10.3892/ol.2017.5682. Epub 2017 Feb 07.

Aneurysmal bone cysts (ABCs) are benign bony lesions frequently accompanied by multiple cystic lesions and aggressive bone destruction. They are relatively rare lesions, representing only 1% of bone tumors. The pathogenesis of ABCs has yet to be elucidated. In...

Focal partial salvage low-dose-rate brachytherapy for local recurrent prostate cancer after permanent prostate brachytherapy with a review of the literature.

Journal of contemporary brachytherapy

Kunogi H, Wakumoto Y, Yamaguchi N, Horie S, Sasai K.
PMID: 27504124
J Contemp Brachytherapy. 2016 Jun;8(3):165-72. doi: 10.5114/jcb.2016.60452. Epub 2016 Jun 13.

PURPOSE: To investigate the treatment results for focal partial salvage re-implantation against local recurrence after permanent prostate brachytherapy.MATERIAL AND METHODS: Between January 2010 and September 2015, 12 patients were treated with focal partial salvage re-implantation for local recurrence after...

Morphological comparison and functional reconstitution of rat hepatic parenchymal cells on various matrices.

Journal of gastroenterology and hepatology

Awata R, Sawai H, Imai K, Terada K, Senoo H, Sugiyama T.
PMID: 28976700
J Gastroenterol Hepatol. 1998 Sep;13:S55-S61. doi: 10.1111/jgh.1998.13.s1.55.

Four types of materials, type I collagen coat (Coat), acid-soluble type I collagen gel (Hardgel), pepsin-treated acid-soluble type I collagen gel (Softgel), and an extract of extracellular matrix of the murine Engelbreth-Holm-Swarm sarcoma (Matrigel), were used as matrices to...

Dielectric Mismatch Mediates Carrier Mobility in Organic-Intercalated Layered TiS2.

Nano letters

Wan C, Kodama Y, Kondo M, Sasai R, Qian X, Gu X, Koga K, Yabuki K, Yang R, Koumoto K.
PMID: 26308495
Nano Lett. 2015 Oct 14;15(10):6302-8. doi: 10.1021/acs.nanolett.5b01013. Epub 2015 Sep 01.

The dielectric constant is a key parameter that determines both optical and electronic properties of materials. It is desirable to tune electronic properties though dielectric engineering approach. Here, we present a systematic approach to tune carrier mobilities of hybrid...

Establishment of Immortalized Human Hepatocytes by Introduction of HPV16 E6/E7 and hTERT as Cell Sources for Liver Cell-Based Therapy.

Cell transplantation

Tsuruga Y, Kiyono T, Matsushita M, Takahashi T, Kasai H, Todo S.
PMID: 28863749
Cell Transplant. 2008 Sep;17(9):1083-1094. doi: 10.3727/096368908786991542.

For future cell-based therapies for liver diseases, the shortage of cell sources must be resolved. Immortalized human hepatocytes are expected to be among the new sources. In addition to telomerase activation by the introduction of human telomerase reverse transcriptase...

Alkali burn treated with 2% rebamipide ophthalmic suspension: a case report.

Case reports in ophthalmology

Sasaki H, Kokubun T.
PMID: 25762927
Case Rep Ophthalmol. 2014 Nov 20;5(3):380-5. doi: 10.1159/000369201. eCollection 2014.

A 47-year-old man presented at the Ophthalmology Department of Saku City Asama General Hospital complaining of hyperemia and pain after industrial sodium hydroxide (approx. 40% concentration) had entered his left eye. With an epithelial defect of the bulbar and...

Showing 1 to 12 of 1840 entries