Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 1 to 12 of 202 entries
Sorted by: Best Match Show Resources per page
Immunohistochemical assays incorporating SP142 and 22C3 monoclonal antibodies for detection of PD-L1 expression in NSCLC patients with known status of .

Oncotarget

Krawczyk P, Jarosz B, Kucharczyk T, Grenda A, Reszka K, Pankowski J, Wojas-Krawczyk K, Nicoś M, Szumiło J, Trojanowski T, Milanowski J.
PMID: 28969070
Oncotarget. 2017 Jul 31;8(38):64283-64293. doi: 10.18632/oncotarget.19724. eCollection 2017 Sep 08.

Different immunohistochemical (IHC) assays were approved for PD-L1 expression examination on tumor cells in qualification to immune-checkpoint inhibitors therapy in NSCLC patients. These assays have some similarities, but also very serious differences. We assessed 2 IHC tests for PD-L1...

Progression of motor neuron disease is accelerated and the ability to recover is compromised with advanced age in rNLS8 mice.

Acta neuropathologica communications

Spiller KJ, Restrepo CR, Khan T, Stieber AM, Kwong LK, Trojanowski JQ, Lee VM.
PMID: 27687289
Acta Neuropathol Commun. 2016 Sep 29;4(1):105. doi: 10.1186/s40478-016-0377-5.

In order to treat progressive paralysis in ALS patients, it is critical to develop a mouse that closely models human ALS in both pathology and also in the timing of these events. We have recently generated new TDP-43 bigenic...

Alzheimer's disease centers and the dementias of aging program of the national institute on aging: a brief overview.

Journal of Alzheimer's disease : JAD

Trojanowski JQ.
PMID: 12214066
J Alzheimers Dis. 2001 Apr;3(2):249-251. doi: 10.3233/jad-2001-3210.

The National Institute on Aging (NIA) of the National Institutes of Health (NIH) has stimulated many recent landmark advances in the understanding and treatment of Alzheimer's disease (AD) and related dementing disorders. This progress is due in part to...

Ways toward an early diagnosis in Alzheimer's disease: the Alzheimer's Disease Neuroimaging Initiative (ADNI).

Alzheimer's & dementia : the journal of the Alzheimer's Association

Mueller SG, Weiner MW, Thal LJ, Petersen RC, Jack CR, Jagust W, Trojanowski JQ, Toga AW, Beckett L.
PMID: 17476317
Alzheimers Dement. 2005 Jul;1(1):55-66. doi: 10.1016/j.jalz.2005.06.003.

With the increasing life expectancy in developed countries, the incidence of Alzheimer's disease (AD) and thus its socioeconomic impact are growing. Increasing knowledge over the last years about the pathomechanisms involved in AD allow for the development of specific...

Impact of prediation on the evolution of European bird life histories.

Trends in ecology & evolution

Tryjanowski P.
PMID: 21237961
Trends Ecol Evol. 1997 Jan;12(1):33. doi: 10.1016/s0169-5347(97)88392-9.

No abstract available.

Computed tomography perfusion examination is helpful in evaluating the extent of oropharyngeal and oral cavity cancer.

Polish journal of radiology

Trojanowska A, Grzycka-Kowalczyk L, Trojanowski P, Klatka J, Drop A.
PMID: 22802811
Pol J Radiol. 2011 Jan;76(1):14-9.

BACKGROUND: Squamous cell cancer (SCC) of the head and neck, like other malignancies, should be reported with regard to TNM classification and treated accordingly. Sole anatomic imaging has its drawbacks, as early lesion detection often remains challenging, non-neoplastic processes...

Effects of habitat and time of day on flock size of Turkey Vultures in Cuba (.

ZooKeys

Tryjanowski P, Morelli F.
PMID: 29362546
Zookeys. 2018 Jan 08;(726):79-86. doi: 10.3897/zookeys.726.14581. eCollection 2018.

In agricultural landscapes, the Turkey Vulture

Cognitive Functional Abilities in Parkinson's Disease: Agreement Between Patients and Informants.

Movement disorders clinical practice

Deck BL, Xie SX, Choi G, Rick J, Siderowf A, Rudovsky S, Chen-Plotkin A, Duda JE, Morley JF, Dahodwala N, Trojanowski JQ, Weintraub D.
PMID: 31392244
Mov Disord Clin Pract. 2019 May 17;6(6):440-445. doi: 10.1002/mdc3.12781. eCollection 2019 Jul.

BACKGROUND: The Penn Parkinson's Daily Activities Questionnaire-15 (PDAQ-15) assesses cognition-related instrumental activities of daily living (IADL) in Parkinson's disease (PD).OBJECTIVES: To assess the degree and predictors of disagreement between patients (PT) and knowledgeable informants (KI) on the PDAQ-15.METHODS: We...

Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group.

ACS medicinal chemistry letters

Lassalas P, Oukoloff K, Makani V, James M, Tran V, Yao Y, Huang L, Vijayendran K, Monti L, Trojanowski JQ, Lee VM, Kozlowski MC, Smith AB, Brunden KR, Ballatore C.
PMID: 28835803
ACS Med Chem Lett. 2017 Jul 05;8(8):864-868. doi: 10.1021/acsmedchemlett.7b00212. eCollection 2017 Aug 10.

The oxetane ring serves as an isostere of the carbonyl moiety, suggesting that oxetan-3-ol may be considered as a potential surrogate of the carboxylic acid functional group. To investigate this structural unit, as well as thietan-3-ol and the corresponding...

Urban plums and toads: do fleshy fruits affect the post-metamorphic growth of amphibians?.

PeerJ

Kaczmarski M, Tryjanowski P, Kubicka AM.
PMID: 30723623
PeerJ. 2019 Jan 30;7:e6337. doi: 10.7717/peerj.6337. eCollection 2019.

BACKGROUND: The main aim of the study was to analyse the influence of fleshy fruits (plums) on the post-metamorphic growth and feeding behaviour of the green toad METHODS: A total of 120 fresh metamorphs of the green toad were...

The effect of pre-laying maternal immunization on offspring growth and immunity differs across experimentally altered postnatal rearing conditions in a wild songbird.

Frontiers in zoology

Martyka R, Śliwińska EB, Martyka M, Cichoń M, Tryjanowski P.
PMID: 29946341
Front Zool. 2018 Jun 19;15:25. doi: 10.1186/s12983-018-0272-y. eCollection 2018.

BACKGROUND: Prenatal antibody transfer is an immune-mediated maternal effect by which females can shape postnatal offspring resistance to pathogens and parasites. Maternal antibodies passed on to offspring provide primary protection to neonates against diverse pathogenic antigens, but they may...

Derivation of cutoffs for the Elecsys.

Alzheimer's & dementia (Amsterdam, Netherlands)

Shaw LM, Waligorska T, Fields L, Korecka M, Figurski M, Trojanowski JQ, Eichenlaub U, Wahl S, Quan M, Pontecorvo MJ, Lachno DR, Talbot JA, Andersen SW, Siemers ER, Dean RA.
PMID: 30426066
Alzheimers Dement (Amst). 2018 Aug 11;10:698-705. doi: 10.1016/j.dadm.2018.07.002. eCollection 2018.

INTRODUCTION: An Elecsys® Amyloid β (Aβ [1-42]) immunoassay cutoff for classification of patients with Alzheimer's disease was investigated.METHODS: Cerebrospinal fluid samples collected from patients with mild-to-moderate Alzheimer's disease were analyzed by Elecsys® immunoassays: (1) Aβ (1-42), (2) total tau,...

Showing 1 to 12 of 202 entries