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Showing 1 to 12 of 499 entries
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[A survey of the professional life of the Japanese nurse].

Revue de l'infirmiere et de l'assistante sociale

Thenot A, Umehara M.
PMID: 4164443
Rev Infirm Assist Soc. 1967 Apr;17(4):340-3.

No abstract available.

Case series report of navigation-based .

Annals of medicine and surgery (2012)

Takagi H, Asai S, Sato A, Maekawa M, Kawashima H, Kanzaki K.
PMID: 28392915
Ann Med Surg (Lond). 2017 Mar 29;17:33-37. doi: 10.1016/j.amsu.2017.03.032. eCollection 2017 May.

BACKGROUND: Simulations show that paradoxical anterior femoral slide in conventional dual radius total knee arthroplasty (TKA) is initiated by sudden reduction of the femoral radius from distal to posterior. Therefore, we hypothesized that a new TKA prosthesis design with...

Simulation-based training for determination of brain death by pediatric healthcare providers.

SpringerPlus

Araki T, Yokota H, Ichikawa K, Osamura T, Satomi A, Tsuru T, Umehara M, Niitsu T, Yamamoto T, Nishiyama K.
PMID: 26266083
Springerplus. 2015 Aug 12;4:412. doi: 10.1186/s40064-015-1211-4. eCollection 2015.

BACKGROUND: Low competency for determination of brain death (BD) and unfamiliarity with Japanese BD (JBD) criteria among pediatricians were highlighted in previous nationwide studies. Because the JBD criteria were amended in 2010 to allow organ donation from pediatric brain-dead...

Stem Cell Therapy for Treatment of Ocular Disorders.

Stem cells international

Sivan PP, Syed S, Mok PL, Higuchi A, Murugan K, Alarfaj AA, Munusamy MA, Awang Hamat R, Umezawa A, Kumar S.
PMID: 27293447
Stem Cells Int. 2016;2016:8304879. doi: 10.1155/2016/8304879. Epub 2016 May 15.

Sustenance of visual function is the ultimate focus of ophthalmologists. Failure of complete recovery of visual function and complications that follow conventional treatments have shifted search to a new form of therapy using stem cells. Stem cell progenitors play...

Increased .

Oncology letters

Sasaki H, Maekawa M, Tatematsu T, Okuda K, Moriyama S, Yano M, Fujii Y.
PMID: 25621040
Oncol Lett. 2015 Feb;9(2):709-712. doi: 10.3892/ol.2014.2719. Epub 2014 Nov 20.

Point mutation of the

Cullin-3 and its adaptor protein ANKFY1 determine the surface level of integrin β1 in endothelial cells.

Biology open

Maekawa M, Tanigawa K, Sakaue T, Hiyoshi H, Kubota E, Joh T, Watanabe Y, Taguchi T, Higashiyama S.
PMID: 29038302
Biol Open. 2017 Nov 15;6(11):1707-1719. doi: 10.1242/bio.029579.

Angiogenesis, the formation of new blood vessels from the pre-existing vasculature, is related to numerous pathophysiological events. We previously reported that a RING ubiquitin ligase complex scaffold protein, cullin-3 (CUL3), and one of its adaptor proteins, BAZF, regulated angiogenesis...

A case of treatment with voriconazole for chronic progressive pulmonary aspergillosis in a patient receiving tacrolimus for dermatomyositis-associated interstitial lung disease.

Respiratory medicine case reports

Mochizuki E, Furuhashi K, Fujisawa T, Enomoto N, Inui N, Nakamura Y, Kono M, Hamada E, Maekawa M, Suda T.
PMID: 26744690
Respir Med Case Rep. 2015 Nov 03;16:163-5. doi: 10.1016/j.rmcr.2015.10.008. eCollection 2015.

We report a successful treatment with voriconazole (VRCZ) for chronic progressive pulmonary aspergillosis (CPPA) in a patient with dermatomyositis-associated interstitial lung disease (DM-ILD) treated with tacrolimus. A 73-year-old man with DM-ILD, treated with tacrolimus and prednisolone, complained of productive...

In vitro transdifferentiation of human peripheral blood mononuclear cells to photoreceptor-like cells.

Biology open

Komuta Y, Ishii T, Kaneda M, Ueda Y, Miyamoto K, Toyoda M, Umezawa A, Seko Y.
PMID: 27170256
Biol Open. 2016 Jun 15;5(6):709-19. doi: 10.1242/bio.016477.

Direct reprogramming is a promising, simple and low-cost approach to generate target cells from somatic cells without using induced pluripotent stem cells. Recently, peripheral blood mononuclear cells (PBMCs) have attracted considerable attention as a somatic cell source for reprogramming....

Inhibition of NF-κB Activity Enhances Sensitivity to Anticancer Drugs in Cholangiocarcinoma Cells.

Oncology research

Seubwai W, Vaeteewoottacharn K, Kraiklang R, Umezawa K, Okada S, Wongkham S.
PMID: 29021017
Oncol Res. 2016 Jan 21;23(1):21-28. doi: 10.3727/096504015X14424348426071.

Cholangiocarcinoma (CCA) is a dismal cancer. At present, there is no effective chemotherapeutic regimen for CCA. This may be due to the marked resistance of CCA to chemotherapy drugs, for which a mechanism remains unknown. Nuclear factor-κB (NF-κB) is...

N- and O-glycan cell surface protein modifications associated with cellular senescence and human aging.

Cell & bioscience

Itakura Y, Sasaki N, Kami D, Gojo S, Umezawa A, Toyoda M.
PMID: 26893823
Cell Biosci. 2016 Feb 18;6:14. doi: 10.1186/s13578-016-0079-5. eCollection 2016.

BACKGROUND: Glycans play essential roles in biological functions such as differentiation and cancer. Recently, glycans have been considered as biomarkers for physiological aging. However, details regarding the specific glycans involved are limited. Here, we investigated cellular senescence- and human...

Molecular Epidemiology of Rubella Virus Strains Detected Around the Time of the 2012-2013 Epidemic in Japan.

Frontiers in microbiology

Mori Y, Miyoshi M, Kikuchi M, Sekine M, Umezawa M, Saikusa M, Matsushima Y, Itamochi M, Yasui Y, Kanbayashi D, Miyoshi T, Akiyoshi K, Tatsumi C, Zaitsu S, Kadoguchi M, Otsuki N, Okamoto K, Sakata M, Komase K, Takeda M.
PMID: 28848523
Front Microbiol. 2017 Aug 09;8:1513. doi: 10.3389/fmicb.2017.01513. eCollection 2017.

A nationwide rubella epidemic occurred from 2012 to 2013 in Japan, resulting in around 17,000 rubella cases and the birth of 45 infants with congenital rubella syndrome. The aim of this study was to genetically characterize the rubella viruses...

Systematic control of the excited-state dynamics and carrier-transport properties of functionalized benzo[ghi]perylene and coronene derivatives.

Chemistry (Weinheim an der Bergstrasse, Germany)

Hirayama S, Sakai H, Araki Y, Tanaka M, Imakawa M, Wada T, Takenobu T, Hasobe T.
PMID: 24953934
Chemistry. 2014 Jul 14;20(29):9081-93. doi: 10.1002/chem.201304679. Epub 2014 Jun 20.

A series of benzo[ghi]perylene (Bp) and coronene (Cor) derivatives substituted with electron-withdrawing methoxycarbonyl (COOMe) or electron-donating methoxyl (MeO) groups was synthesized. The electrochemical, spectroscopic, and photophysical properties of these compounds were investigated by cyclic voltammetry, steady-state and time-resolved spectroscopy,...

Showing 1 to 12 of 499 entries