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Showing 1 to 12 of 91 entries
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Automated Brightness and Contrast Adjustment of Color Fundus Photographs for the Grading of Age-Related Macular Degeneration.

Translational vision science & technology

Tsikata E, Laíns I, Gil J, Marques M, Brown K, Mesquita T, Melo P, da Luz Cachulo M, Kim IK, Vavvas D, Murta JN, Miller JB, Silva R, Miller JW, Chen TC, Husain D.
PMID: 28316876
Transl Vis Sci Technol. 2017 Mar 13;6(2):3. doi: 10.1167/tvst.6.2.3. eCollection 2017 Mar.

PURPOSE: The purpose of this study was to develop an algorithm to automatically standardize the brightness, contrast, and color balance of digital color fundus photographs used to grade AMD and to validate this algorithm by determining the effects of...

Necrotic enlargement of cone photoreceptor cells and the release of high-mobility group box-1 in retinitis pigmentosa.

Cell death discovery

Murakami Y, Ikeda Y, Nakatake S, Tachibana T, Fujiwara K, Yoshida N, Notomi S, Nakao S, Hisatomi T, Miller JW, Vavvas DG, Sonoda KH, Ishibashi T.
PMID: 27551484
Cell Death Discov. 2015 Nov 30;1:15058. doi: 10.1038/cddiscovery.2015.58. eCollection 2015.

Retinitis pigmentosa (RP) refers to a group of inherited retinal degenerations resulting form rod and cone photoreceptor cell death. The rod cell death due to deleterious genetic mutations has been shown to occur mainly through apoptosis, whereas the mechanisms...

Real-world treatment of diabetic macular oedema: a comparison of combined ranibizumab plus macular LASER with macular LASER monotherapy.

Hellenic journal of nuclear medicine

Zygoura V, Papavasileiou E, Vavvas DG, Cortis D, Eleftheriadis H, Jackson TL.
PMID: 26665210
Hell J Nucl Med. 2015 Sep-Dec;18:33-41.

OBJECTIVE: To study real world outcomes of ranibizumab (Lucentis) intravitreal injection in diabetic macular oedema (DMO).SUBJECTS AND METHODS: We included 100 patients with DMO. Those who had optical coherence tomography central retinal thickness (CRT) of 400μm or more (Group...

Femtosecond laser irradiation of metallic surfaces: effects of laser parameters on superhydrophobicity.

Nanotechnology

Moradi S, Kamal S, Englezos P, Hatzikiriakos SG.
PMID: 24045766
Nanotechnology. 2013 Oct 18;24(41):415302. doi: 10.1088/0957-4484/24/41/415302. Epub 2013 Sep 17.

This work studies in detail the effect of femtosecond laser irradiation process parameters (fluence and scanning speed) on the hydrophobicity of the resulting micro/nano-patterned morphologies on stainless steel. Depending on the laser parameters, four distinctly different nano-patterns were produced,...

Epigenetic Treatment of Neurodegenerative Ophthalmic Disorders: An Eye Toward the Future.

BioResearch open access

Moos WH, Faller DV, Glavas IP, Harpp DN, Irwin MH, Kanara I, Pinkert CA, Powers WR, Steliou K, Vavvas DG, Kodukula K.
PMID: 29291141
Biores Open Access. 2017 Dec 01;6(1):169-181. doi: 10.1089/biores.2017.0036. eCollection 2017.

Eye disease is one of the primary medical conditions that requires attention and therapeutic intervention in ageing populations worldwide. Further, the global burden of diabetes and obesity, along with heart disease, all lead to secondary manifestations of ophthalmic distress....

A New Approach to Treating Neurodegenerative Otologic Disorders.

BioResearch open access

Moos WH, Faller DV, Glavas IP, Harpp DN, Irwin MH, Kanara I, Pinkert CA, Powers WR, Steliou K, Vavvas DG, Kodukula K.
PMID: 30069423
Biores Open Access. 2018 Jul 01;7(1):107-115. doi: 10.1089/biores.2018.0017. eCollection 2018.

Hearing loss, the most common neurological disorder and the fourth leading cause of years lived with disability, can have profound effects on quality of life. The impact of this "invisible disability," with significant consequences, economic and personal, is most...

Novel grid combined with peripheral distortion correction for ultra-widefield image grading of age-related macular degeneration.

Clinical ophthalmology (Auckland, N.Z.)

Oellers P, Laíns I, Mach S, Garas S, Kim IK, Vavvas DG, Miller JW, Husain D, Miller JB.
PMID: 29184386
Clin Ophthalmol. 2017 Nov 08;11:1967-1974. doi: 10.2147/OPTH.S143246. eCollection 2017.

PURPOSE: Eyes with age-related macular degeneration (AMD) often harbor pathological changes in the retinal periphery and perimacular region. These extramacular changes have not been well classified, but may be phenotypically and functionally relevant. The purpose of this study was...

Contrast sensitivity function in patients with macular disease and good visual acuity.

The British journal of ophthalmology

Wai KM, Vingopoulos F, Garg I, Kasetty M, Silverman RF, Katz R, Laíns I, Miller JW, Husain D, Vavvas DG, Kim LA, Miller JB.
PMID: 33536229
Br J Ophthalmol. 2021 Feb 03; doi: 10.1136/bjophthalmol-2020-318494. Epub 2021 Feb 03.

INTRODUCTION: Contrast sensitivity function (CSF) may better estimate a patient's visual function compared with visual acuity (VA). Our study evaluates the quick CSF (qCSF) method to measure visual function in eyes with macular disease and good letter acuity.METHODS: Patients...

Quantitative Comparison Of Microvascular Metrics On Three Optical Coherence Tomography Angiography Devices In Chorioretinal Disease.

Clinical ophthalmology (Auckland, N.Z.)

Lu Y, Wang JC, Zeng R, Katz R, Vavvas DG, Miller JW, Miller JB.
PMID: 31749603
Clin Ophthalmol. 2019 Oct 22;13:2063-2069. doi: 10.2147/OPTH.S215322. eCollection 2019.

PURPOSE: Optical coherence tomography angiography (OCT-A) has emerged as a novel tool for the non-invasive imaging and evaluation of the retinal microvasculature. There is little existing literature that compares OCT-A microvasculature metrics across different OCT-A devices in chorioretinal diseases....

BASELINE PREDICTORS ASSOCIATED WITH 3-YEAR CHANGES IN DARK ADAPTATION IN AGE-RELATED MACULAR DEGENERATION.

Retina (Philadelphia, Pa.)

Lains I, Pundlik SJ, Nigalye A, Katz R, Luo G, Kim IK, Vavvas DG, Miller JW, Miller JB, Husain D.
PMID: 33625114
Retina. 2021 Oct 01;41(10):2098-2105. doi: 10.1097/IAE.0000000000003152.

PURPOSE: To assess the relationship between baseline age-related macular degeneration (AMD) and disease stage, as well as optical coherence tomography features seen in AMD, with 3-year changes in dark adaptation (DA).METHODS: Prospective longitudinal study including patients with AMD and...

A Review of Completed and Ongoing Complement Inhibitor Trials for Geographic Atrophy Secondary to Age-Related Macular Degeneration.

Journal of clinical medicine

Halawa OA, Lin JB, Miller JW, Vavvas DG.
PMID: 34208067
J Clin Med. 2021 Jun 11;10(12). doi: 10.3390/jcm10122580.

Age-related macular degeneration (AMD) is a leading cause of irreversible blindness among older adults in the Western world. While therapies exist for patients with exudative AMD, there are currently no approved therapies for non-exudative AMD and its advanced form...

Osborne-Cotterill Lesion a Forgotten Injury: Review Article and Case Report.

Clinics in shoulder and elbow

Vargas DG, Woodcock S, Porto GF, Gonzalez JC.
PMID: 33330230
Clin Shoulder Elb. 2020 Feb 21;23(1):27-30. doi: 10.5397/cise.2019.00318. eCollection 2020 Mar.

Osborne-Cotterill lesion is an osteochondral fracture located in the posterolateral margin of the humeral capitellum, which may be associated with a defect of the radial head after an elbow dislocation. This lesion causes instability by affecting the lateral ulnar...

Showing 1 to 12 of 91 entries