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Showing 1 to 12 of 1015 entries
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Bringing design to the privacy table: Broadening “design” in “privacy by design” through the lens of HCI

Broadening Participation in Computing AND Program Evaluation

Mulligan DK, Wong RY.
GSID: w5_mLak-ZRYJ
RY Wong, DK Mulligan - … CHI conference on human factors in computing …, 2019 - dl.acm.org

In calls for privacy by design (PBD), regulators and privacy scholars have investigated the richness of the concept of" privacy." In contrast," design" in HCI is comprised of rich and complex concepts and practices, but has received much less...

Nickel-Catalyzed Difluoroalkylation of (Hetero)Arylborons with Unactivated 1-Bromo-1,1-difluoroalkanes.

Angewandte Chemie (International ed. in English)

Xiao YL, Min QQ, Xu C, Wang RW, Zhang X.
PMID: 27060704
Angew Chem Int Ed Engl. 2016 May 04;55(19):5837-41. doi: 10.1002/anie.201601351. Epub 2016 Apr 06.

A nickel-catalyzed cross-coupling between (hetero)arylborons and unactivated 1-bromo-1,1-difluoroalkanes has been developed. The use of two ligands (a bidentate bipyridine-based ligand, 4,4'-ditBu-bpy, and a monodentate pyridine-based ligand, DMAP) offers a highly efficient nickel-based catalytic system to prepare difluoroalkylated arenes which...

Effects of roniciclib in preclinical models of anaplastic thyroid cancer.

Oncotarget

Lin SF, Lin JD, Hsueh C, Chou TC, Wong RJ.
PMID: 28978090
Oncotarget. 2017 Jul 08;8(40):67990-68000. doi: 10.18632/oncotarget.19092. eCollection 2017 Sep 15.

Many human cancers have altered cyclin-dependent kinase activity. Inhibition of cyclin-dependent kinases may arrest cell cycle progression and represents an important strategy in the treatment of malignancies. We evaluated the therapeutic effects of roniciclib, a cyclin-dependent kinase inhibitor, as...

Early-Onset Network Hyperexcitability in Presymptomatic Alzheimer's Disease Transgenic Mice Is Suppressed by Passive Immunization with Anti-Human APP/Aβ Antibody and by mGluR5 Blockade.

Frontiers in aging neuroscience

Kazim SF, Chuang SC, Zhao W, Wong RK, Bianchi R, Iqbal K.
PMID: 28392767
Front Aging Neurosci. 2017 Mar 24;9:71. doi: 10.3389/fnagi.2017.00071. eCollection 2017.

Cortical and hippocampal network hyperexcitability appears to be an early event in Alzheimer's disease (AD) pathogenesis, and may contribute to memory impairment. It remains unclear if network hyperexcitability precedes memory impairment in mouse models of AD and what are...

Bis(mandelato)borate: an effective, inexpensive spiroborate anion for chiral resolution.

Chemical communications (Cambridge, England)

Wong LW, Kan JW, Nguyen TH, Sung HH, Li D, Au-Yeung AS, Sharma R, Lin Z, Williams ID.
PMID: 26369891
Chem Commun (Camb). 2015 Nov 11;51(87):15760-3. doi: 10.1039/c5cc04977f.

Bis(mandelato)borate [B(Man)2](-) (R- or S-) anions are simply prepared and appear widely effective for resolution of racemic cations. Three examples demonstrate their scope; the alkaloid tetrahydropalmatine (THP), 1,2-diaminopropane (1,2-dap) and the metal-organic complex [Co(phen)3](3+) are readily resolved, either by...

Smooth and flat phase-locked Kerr frequency comb generation by higher order mode suppression.

Scientific reports

Huang SW, Liu H, Yang J, Yu M, Kwong DL, Wong CW.
PMID: 27181420
Sci Rep. 2016 May 16;6:26255. doi: 10.1038/srep26255.

High-Q microresonator is perceived as a promising platform for optical frequency comb generation, via dissipative soliton formation. In order to achieve a higher quality factor and obtain the necessary anomalous dispersion, multi-mode waveguides were previously implemented in Si3N4 microresonators....

Continuous control of the nonlinearity phase for harmonic generations.

Nature materials

Li G, Chen S, Pholchai N, Reineke B, Wong PW, Pun EY, Cheah KW, Zentgraf T, Zhang S.
PMID: 25849530
Nat Mater. 2015 Jun;14(6):607-12. doi: 10.1038/nmat4267. Epub 2015 Apr 13.

The capability of locally engineering the nonlinear optical properties of media is crucial in nonlinear optics. Although poling is the most widely employed technique for achieving locally controlled nonlinearity, it leads only to a binary nonlinear state, which is...

FIBER DIRECTION ESTIMATION, SMOOTHING AND TRACKING IN DIFFUSION MRI.

The annals of applied statistics

Wong RKW, Lee TCM, Paul D, Peng J.
PMID: 28638497
Ann Appl Stat. 2016 Sep;10(3):1137-1156. doi: 10.1214/15-AOAS880. Epub 2016 Sep 28.

Diffusion magnetic resonance imaging is an imaging technology designed to probe anatomical architectures of biological samples in an in vivo and noninvasive manner through measuring water diffusion. The contribution of this paper is threefold. First, it proposes a new...

Obesity and non-alcoholic fatty liver disease: Disparate associations among Asian populations.

World journal of hepatology

Wong RJ, Ahmed A.
PMID: 24868320
World J Hepatol. 2014 May 27;6(5):263-73. doi: 10.4254/wjh.v6.i5.263.

Obesity is a global epidemic contributing to an increasing prevalence of obesity-related systemic disorders, including nonalcoholic fatty liver disease. The rising prevalence of nonalcoholic steatohepatitis (NASH) will in the near future lead to end-stage liver disease in a large...

Antifungal mode of action of macrocarpal C extracted from Eucalyptus globulus Labill (Lan An) towards the dermatophyte Trichophyton mentagrophytes.

Chinese medicine

Wong JH, Lau KM, Wu YO, Cheng L, Wong CW, Yew DT, Leung PC, Fung KP, Hui M, Ng TB, Lau CB.
PMID: 26594235
Chin Med. 2015 Nov 21;10:34. doi: 10.1186/s13020-015-0068-3. eCollection 2015.

BACKGROUND: The fresh leaves of Eucalyptus globulus Labill. (Lan An) have been used in Chinese medicine for many years to treat dermatomycosis. Macrocarpal C was isolated from this herb and identified as its major antifungal component by bioassay-guided purification....

Cyclometalation and coupling of a rigid 4,5-bis(imino)acridanide pincer ligand on yttrium.

Dalton transactions (Cambridge, England : 2003)

Wong EW, Emslie DJ.
PMID: 26041684
Dalton Trans. 2015 Jul 07;44(25):11601-12. doi: 10.1039/c5dt01636c.

An extremely rigid NNN-donor proligand, 4,5-bis{(diphenylmethylene)amino}-2,7,9,9-tetramethylacridan, H[AIm2] was prepared in five steps starting from 5-methyl-2-aminobenzoic acid and 4-bromotoluene. Reaction of intensely orange H[AIm2] with LiCH2SiMe3 formed deep blue Li(x)[AIm2]x (x = 2 in the solid state), while reaction with...

Recurrent pneumothorax: the unexpected encounters.

Annals of translational medicine

Ng CS, Wong RH, Lau RW, Kwok MW.
PMID: 26015940
Ann Transl Med. 2015 May;3(7):98. doi: 10.3978/j.issn.2305-5839.2015.04.08.

No abstract available.

Showing 1 to 12 of 1015 entries