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Control of ion and fluid transport by putative second messengers in different segments of the Malpighian tubules of the black field cricket Teleogryllus oceanicus.

Journal of insect physiology

Xu W, Marshall AT.
PMID: 12770255
J Insect Physiol. 2000 Jan;46(1):21-31. doi: 10.1016/s0022-1910(99)00097-9.

The differences in second messenger control of secretion were investigated in the distal and main segments of the Malpighian tubules of the black field cricket Teleogryllus oceanicus. Secretion by the main segment was considerably increased by corpora cardiaca extract...

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Xu W, Marshall AT. Control of ion and fluid transport by putative second messengers in different segments of the Malpighian tubules of the black field cricket Teleogryllus oceanicus. J Insect Physiol. 2000;46(1):21-31doi: 10.1016/s0022-1910(99)00097-9.
Xu, W., & Marshall, A. T. (2000). Control of ion and fluid transport by putative second messengers in different segments of the Malpighian tubules of the black field cricket Teleogryllus oceanicus. Journal of insect physiology, 46(1), 21-31. https://doi.org/10.1016/s0022-1910(99)00097-9
Xu, W, and Marshall, A T.. "Control of ion and fluid transport by putative second messengers in different segments of the Malpighian tubules of the black field cricket Teleogryllus oceanicus." Journal of insect physiology vol. 46,1 (2000): 21-31. doi: https://doi.org/10.1016/s0022-1910(99)00097-9
Xu W, Marshall AT. Control of ion and fluid transport by putative second messengers in different segments of the Malpighian tubules of the black field cricket Teleogryllus oceanicus. J Insect Physiol. 2000 Jan;46(1):21-31. doi: 10.1016/s0022-1910(99)00097-9. PMID: 12770255.
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G protein beta(1)gamma (2) subunits purification and their interaction with adenylyl cyclase.

Science in China. Series C, Life sciences

Chen J, Ni H, Sun J, Weng G.
PMID: 18758712
Sci China C Life Sci. 2003 Apr;46(2):212-23. doi: 10.1360/03yc9023.

A preliminary study on the interaction of G protein (guanine triphosphate binding protein) beta(1)gamma(2) subunits and their coupled components in cell signal transduction was conducted in vitro. The insect cell lines, Sf9 (Spodoptera frugiperda) and H5 (Trichoplusia ni) were...

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Chen J, Ni H, Sun J, et al. G protein beta(1)gamma (2) subunits purification and their interaction with adenylyl cyclase. Sci China C Life Sci. 2003;46(2):212-23doi: 10.1360/03yc9023.
Chen, J., Ni, H., Sun, J., & Weng, G. (2003). G protein beta(1)gamma (2) subunits purification and their interaction with adenylyl cyclase. Science in China. Series C, Life sciences, 46(2), 212-23. https://doi.org/10.1360/03yc9023
Chen, Julian, et al. "G protein beta(1)gamma (2) subunits purification and their interaction with adenylyl cyclase." Science in China. Series C, Life sciences vol. 46,2 (2003): 212-23. doi: https://doi.org/10.1360/03yc9023
Chen J, Ni H, Sun J, Weng G. G protein beta(1)gamma (2) subunits purification and their interaction with adenylyl cyclase. Sci China C Life Sci. 2003 Apr;46(2):212-23. doi: 10.1360/03yc9023. PMID: 18758712.
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Circadian Oscillations within the Hippocampus Support Memory Formation and Persistence.

Frontiers in molecular neuroscience

Eckel-Mahan KL.
PMID: 22529773
Front Mol Neurosci. 2012 Apr 18;5:46. doi: 10.3389/fnmol.2012.00046. eCollection 2012.

The ability to sustain memories over long periods of time, sometimes even a lifetime, is one of the most remarkable properties of the brain. Much knowledge has been gained over the past few decades regarding the molecular correlates of...

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Eckel-Mahan KL. Circadian Oscillations within the Hippocampus Support Memory Formation and Persistence. Front Mol Neurosci. 2012;5:46doi: 10.3389/fnmol.2012.00046.
Eckel-Mahan, K. L. (2012). Circadian Oscillations within the Hippocampus Support Memory Formation and Persistence. Frontiers in molecular neuroscience, 546. https://doi.org/10.3389/fnmol.2012.00046
Eckel-Mahan, Kristin L. "Circadian Oscillations within the Hippocampus Support Memory Formation and Persistence." Frontiers in molecular neuroscience vol. 5 (2012): 46. doi: https://doi.org/10.3389/fnmol.2012.00046
Eckel-Mahan KL. Circadian Oscillations within the Hippocampus Support Memory Formation and Persistence. Front Mol Neurosci. 2012 Apr 18;5:46. doi: 10.3389/fnmol.2012.00046. eCollection 2012. PMID: 22529773; PMCID: PMC3328119.
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A Concise Synthesis of Forskolin.

Angewandte Chemie (International ed. in English)

Hylse O, Maier L, Kučera R, Perečko T, Svobodová A, Kubala L, Paruch K, Švenda J.
PMID: 28782270
Angew Chem Int Ed Engl. 2017 Oct 02;56(41):12586-12589. doi: 10.1002/anie.201706809. Epub 2017 Sep 05.

A 24-step synthesis of (±)-forskolin is presented, which delivered hundred milligram quantities of this complex diterpene in one pass. Transformations key to our approach include: a) a strategic allylic transposition, b) stepwise assembly of a sterically encumbered isoxazole ring,...

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Hylse O, Maier L, Kučera R, et al. A Concise Synthesis of Forskolin. Angew Chem Int Ed Engl. 2017;56(41):12586-12589doi: 10.1002/anie.201706809.
Hylse, O., Maier, L., Kučera, R., Perečko, T., Svobodová, A., Kubala, L., Paruch, K., & Švenda, J. (2017). A Concise Synthesis of Forskolin. Angewandte Chemie (International ed. in English), 56(41), 12586-12589. https://doi.org/10.1002/anie.201706809
Hylse, Ondřej, et al. "A Concise Synthesis of Forskolin." Angewandte Chemie (International ed. in English) vol. 56,41 (2017): 12586-12589. doi: https://doi.org/10.1002/anie.201706809
Hylse O, Maier L, Kučera R, Perečko T, Svobodová A, Kubala L, Paruch K, Švenda J. A Concise Synthesis of Forskolin. Angew Chem Int Ed Engl. 2017 Oct 02;56(41):12586-12589. doi: 10.1002/anie.201706809. Epub 2017 Sep 05. PMID: 28782270.
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Evaluation of calcium-sensitive adenylyl cyclase AC1 and AC8 mRNA expression in the anterior cingulate cortex of mice with spared nerve injury neuropathy.

Neurobiology of pain (Cambridge, Mass.)

Shiers S, Elahi H, Hennen S, Price TJ.
PMID: 35005298
Neurobiol Pain. 2021 Dec 21;11:100081. doi: 10.1016/j.ynpai.2021.100081. eCollection 2022.

The anterior cingulate cortex (ACC) is a critical region of the brain for the emotional and affective components of pain in rodents and humans. Hyperactivity in this region has been observed in neuropathic pain states in both patients and...

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Shiers S, Elahi H, Hennen S, et al. Evaluation of calcium-sensitive adenylyl cyclase AC1 and AC8 mRNA expression in the anterior cingulate cortex of mice with spared nerve injury neuropathy. Neurobiol Pain. 2021;11:100081doi: 10.1016/j.ynpai.2021.100081.
Shiers, S., Elahi, H., Hennen, S., & Price, T. J. (2022). Evaluation of calcium-sensitive adenylyl cyclase AC1 and AC8 mRNA expression in the anterior cingulate cortex of mice with spared nerve injury neuropathy. Neurobiology of pain (Cambridge, Mass.), 11100081. https://doi.org/10.1016/j.ynpai.2021.100081
Shiers, Stephanie, et al. "Evaluation of calcium-sensitive adenylyl cyclase AC1 and AC8 mRNA expression in the anterior cingulate cortex of mice with spared nerve injury neuropathy." Neurobiology of pain (Cambridge, Mass.) vol. 11 (2022): 100081. doi: https://doi.org/10.1016/j.ynpai.2021.100081
Shiers S, Elahi H, Hennen S, Price TJ. Evaluation of calcium-sensitive adenylyl cyclase AC1 and AC8 mRNA expression in the anterior cingulate cortex of mice with spared nerve injury neuropathy. Neurobiol Pain. 2021 Dec 21;11:100081. doi: 10.1016/j.ynpai.2021.100081. eCollection 2022. PMID: 35005298; PMCID: PMC8715370.
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Calcium regulation of adenylyl cyclase relevance for endocrine control.

Trends in endocrinology and metabolism: TEM

Antoni FA.
PMID: 18406780
Trends Endocrinol Metab. 1997 Jan-Feb;8(1):7-14. doi: 10.1016/s1043-2760(96)00206-8.

A fundamental process in the hormonal regulation of body functions is the conversion of the intercellular signal into an intracellular signal. The first recognized intracellular messengers mediating the actions of hormones were calcium ions (Ca(2+)) and adenosine 3':5' monophosphate...

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Antoni FA. Calcium regulation of adenylyl cyclase relevance for endocrine control. Trends Endocrinol Metab. 1997;8(1):7-14doi: 10.1016/s1043-2760(96)00206-8.
Antoni, F. A. (1997). Calcium regulation of adenylyl cyclase relevance for endocrine control. Trends in endocrinology and metabolism: TEM, 8(1), 7-14. https://doi.org/10.1016/s1043-2760(96)00206-8
Antoni, F A. "Calcium regulation of adenylyl cyclase relevance for endocrine control." Trends in endocrinology and metabolism: TEM vol. 8,1 (1997): 7-14. doi: https://doi.org/10.1016/s1043-2760(96)00206-8
Antoni FA. Calcium regulation of adenylyl cyclase relevance for endocrine control. Trends Endocrinol Metab. 1997 Jan-Feb;8(1):7-14. doi: 10.1016/s1043-2760(96)00206-8. PMID: 18406780.
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Physiological Roles of Mammalian Transmembrane Adenylyl Cyclase Isoforms.

Physiological reviews

Ostrom KF, LaVigne JE, Brust TF, Seifert R, Dessauer CW, Watts VJ, Ostrom RS.
PMID: 34698552
Physiol Rev. 2021 Oct 26; doi: 10.1152/physrev.00013.2021. Epub 2021 Oct 26.

Adenylyl cyclases (ACs) catalyze the conversion of ATP to the ubiquitous second messenger cAMP. Mammals possess nine isoforms of transmembrane ACs, dubbed AC1-9, that serve as major effector enzymes of G protein-coupled receptors. The transmembrane ACs display varying expression...

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Ostrom KF, LaVigne JE, Brust TF, et al. Physiological Roles of Mammalian Transmembrane Adenylyl Cyclase Isoforms. Physiol Rev. 2021;doi: 10.1152/physrev.00013.2021.
Ostrom, K. F., LaVigne, J. E., Brust, T. F., Seifert, R., Dessauer, C. W., Watts, V. J., & Ostrom, R. S. (2021). Physiological Roles of Mammalian Transmembrane Adenylyl Cyclase Isoforms. Physiological reviews, . https://doi.org/10.1152/physrev.00013.2021
Ostrom, Katrina F, et al. "Physiological Roles of Mammalian Transmembrane Adenylyl Cyclase Isoforms." Physiological reviews vol. (2021). doi: https://doi.org/10.1152/physrev.00013.2021
Ostrom KF, LaVigne JE, Brust TF, Seifert R, Dessauer CW, Watts VJ, Ostrom RS. Physiological Roles of Mammalian Transmembrane Adenylyl Cyclase Isoforms. Physiol Rev. 2021 Oct 26; doi: 10.1152/physrev.00013.2021. Epub 2021 Oct 26. PMID: 34698552.
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Adenylyl cyclases and TRPV4 mediate Ca.

Journal of molecular biochemistry

Moore ER, Ryu HS, Zhu YX, Jacobs CR.
PMID: 31123666
J Mol Biochem. 2018;7:48-59.

Bone adapts to physical forces and this process is dependent on osteocyte mechanotransduction. One way osteocytes sense mechanical stimulation is through the primary cilium, a sensory organelle that triggers intracellular signaling cascades in response to fluid shear. Our lab...

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Moore ER, Ryu HS, Zhu YX, et al. Adenylyl cyclases and TRPV4 mediate Ca. J Mol Biochem. 2018;7:48-59
Moore, E. R., Ryu, H. S., Zhu, Y. X., & Jacobs, C. R. (2018). Adenylyl cyclases and TRPV4 mediate Ca. Journal of molecular biochemistry, 748-59.
Moore, Emily R, et al. "Adenylyl cyclases and TRPV4 mediate Ca." Journal of molecular biochemistry vol. 7 (2018): 48-59.
Moore ER, Ryu HS, Zhu YX, Jacobs CR. Adenylyl cyclases and TRPV4 mediate Ca. J Mol Biochem. 2018;7:48-59. PMID: 31123666; PMCID: PMC6529196.
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Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses.

Frontiers in cell and developmental biology

Adzika GK, Hou H, Adekunle AO, Rizvi R, Adzraku SY, Li K, Deng QM, Mprah R, Ndzie Noah ML, Adu-Amankwaah J, Machuki JO, Shang W, Ma T, Koda S, Ma X, Sun H.
PMID: 34631707
Front Cell Dev Biol. 2021 Sep 24;9:719351. doi: 10.3389/fcell.2021.719351. eCollection 2021.

Chronic catecholamine stress (CCS) induces the occurrence of cardiomyopathy-pathological cardiac hypertrophy (PCH), which is characterized by left ventricular systolic dysfunction (LVSD). Recently, mounting evidence has implicated myocardial inflammation in the exacerbation of pathological cardiac remodeling. However, there are currently...

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Adzika GK, Hou H, Adekunle AO, et al. Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses. Front Cell Dev Biol. 2021;9:719351doi: 10.3389/fcell.2021.719351.
Adzika, G. K., Hou, H., Adekunle, A. O., Rizvi, R., Adzraku, S. Y., Li, K., Deng, Q. M., Mprah, R., Ndzie Noah, M. L., Adu-Amankwaah, J., Machuki, J. O., Shang, W., Ma, T., Koda, S., Ma, X., & Sun, H. (2021). Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses. Frontiers in cell and developmental biology, 9719351. https://doi.org/10.3389/fcell.2021.719351
Adzika, Gabriel Komla, et al. "Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses." Frontiers in cell and developmental biology vol. 9 (2021): 719351. doi: https://doi.org/10.3389/fcell.2021.719351
Adzika GK, Hou H, Adekunle AO, Rizvi R, Adzraku SY, Li K, Deng QM, Mprah R, Ndzie Noah ML, Adu-Amankwaah J, Machuki JO, Shang W, Ma T, Koda S, Ma X, Sun H. Amlexanox and Forskolin Prevents Isoproterenol-Induced Cardiomyopathy by Subduing Cardiomyocyte Hypertrophy and Maladaptive Inflammatory Responses. Front Cell Dev Biol. 2021 Sep 24;9:719351. doi: 10.3389/fcell.2021.719351. eCollection 2021. PMID: 34631707; PMCID: PMC8497899.
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Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - A missed opportunity.

Seminars in cancer biology

Perez DR, Sklar LA, Chigaev A, Matlawska-Wasowska K.
PMID: 32044470
Semin Cancer Biol. 2021 Jan;68:199-208. doi: 10.1016/j.semcancer.2020.02.004. Epub 2020 Feb 07.

While current treatment regimens for acute leukemia can dramatically improve patient survival, there remains room for improvement. Due to its roles in cell differentiation, cell survival, and apoptotic signaling, modulation of the cyclic AMP (cAMP) pathway has provided a...

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Perez DR, Sklar LA, Chigaev A, et al. Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - A missed opportunity. Semin Cancer Biol. 2020;68:199-208doi: 10.1016/j.semcancer.2020.02.004.
Perez, D. R., Sklar, L. A., Chigaev, A., & Matlawska-Wasowska, K. (2021). Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - A missed opportunity. Seminars in cancer biology, 68199-208. https://doi.org/10.1016/j.semcancer.2020.02.004
Perez, Dominique R, et al. "Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - A missed opportunity." Seminars in cancer biology vol. 68 (2021): 199-208. doi: https://doi.org/10.1016/j.semcancer.2020.02.004
Perez DR, Sklar LA, Chigaev A, Matlawska-Wasowska K. Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - A missed opportunity. Semin Cancer Biol. 2021 Jan;68:199-208. doi: 10.1016/j.semcancer.2020.02.004. Epub 2020 Feb 07. PMID: 32044470; PMCID: PMC7415530.
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Members of the KCTD family are major regulators of cAMP signaling.

Proceedings of the National Academy of Sciences of the United States of America

Muntean BS, Marwari S, Li X, Sloan DC, Young BD, Wohlschlegel JA, Martemyanov KA.
PMID: 34934014
Proc Natl Acad Sci U S A. 2022 Jan 04;119(1). doi: 10.1073/pnas.2119237119.

Cyclic adenosine monophosphate (cAMP) is a pivotal second messenger with an essential role in neuronal function. cAMP synthesis by adenylyl cyclases (AC) is controlled by G protein-coupled receptor (GPCR) signaling systems. However, the network of molecular players involved in...

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Muntean BS, Marwari S, Li X, et al. Members of the KCTD family are major regulators of cAMP signaling. Proc Natl Acad Sci U S A. 2022;119(1)doi: 10.1073/pnas.2119237119.
Muntean, B. S., Marwari, S., Li, X., Sloan, D. C., Young, B. D., Wohlschlegel, J. A., & Martemyanov, K. A. (2022). Members of the KCTD family are major regulators of cAMP signaling. Proceedings of the National Academy of Sciences of the United States of America, 119(1), . https://doi.org/10.1073/pnas.2119237119
Muntean, Brian S, et al. "Members of the KCTD family are major regulators of cAMP signaling." Proceedings of the National Academy of Sciences of the United States of America vol. 119,1 (2022). doi: https://doi.org/10.1073/pnas.2119237119
Muntean BS, Marwari S, Li X, Sloan DC, Young BD, Wohlschlegel JA, Martemyanov KA. Members of the KCTD family are major regulators of cAMP signaling. Proc Natl Acad Sci U S A. 2022 Jan 04;119(1). doi: 10.1073/pnas.2119237119. PMID: 34934014.
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Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - A missed opportunity.

Seminars in cancer biology

Perez DR, Sklar LA, Chigaev A, Matlawska-Wasowska K.
PMID: 32044470
Semin Cancer Biol. 2021 Jan;68:199-208. doi: 10.1016/j.semcancer.2020.02.004. Epub 2020 Feb 07.

While current treatment regimens for acute leukemia can dramatically improve patient survival, there remains room for improvement. Due to its roles in cell differentiation, cell survival, and apoptotic signaling, modulation of the cyclic AMP (cAMP) pathway has provided a...

Cite
Perez DR, Sklar LA, Chigaev A, et al. Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - A missed opportunity. Semin Cancer Biol. 2020;68:199-208doi: 10.1016/j.semcancer.2020.02.004.
Perez, D. R., Sklar, L. A., Chigaev, A., & Matlawska-Wasowska, K. (2021). Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - A missed opportunity. Seminars in cancer biology, 68199-208. https://doi.org/10.1016/j.semcancer.2020.02.004
Perez, Dominique R, et al. "Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - A missed opportunity." Seminars in cancer biology vol. 68 (2021): 199-208. doi: https://doi.org/10.1016/j.semcancer.2020.02.004
Perez DR, Sklar LA, Chigaev A, Matlawska-Wasowska K. Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - A missed opportunity. Semin Cancer Biol. 2021 Jan;68:199-208. doi: 10.1016/j.semcancer.2020.02.004. Epub 2020 Feb 07. PMID: 32044470; PMCID: PMC7415530.
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Showing 1 to 12 of 39 entries