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Crystal structures of penicillin‐binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms

STEM and males

Males A, Nettleship JE, Ren J, Stuart DI.
GSID: RLhj-jyBnqsJ
J Ren, JE Nettleship, A Males, DI Stuart… - FEBS letters, 2016 - Wiley Online Library

… PBP3 and other penicillin-binding proteins are inhibited by β-lactam antibiotics which act as suicide substrates [2, 3] by mimicking the D-alanyl-D-alanine stem peptide of the …

[Greetings from merry Grusia].

Katilolehti

Laine A.
PMID: 252561
Katilolehti. 1978 Dec;83(12):479-84.

No abstract available.

Ingesting a pre-workout supplement containing caffeine, B-vitamins, amino acids, creatine, and beta-alanine before exercise delays fatigue while improving reaction time and muscular endurance.

Nutrition & metabolism

Spradley BD, Crowley KR, Tai CY, Kendall KL, Fukuda DH, Esposito EN, Moon SE, Moon JR.
PMID: 22463603
Nutr Metab (Lond). 2012 Mar 30;9:28. doi: 10.1186/1743-7075-9-28.

BACKGROUND: The purpose of this study was to determine the effects of the pre-workout supplement Assault™ (MusclePharm, Denver, CO, USA) on upper and lower body muscular endurance, aerobic and anaerobic capacity, and choice reaction time in recreationally-trained males. Subjective...

Increasing Hepatitis C treatment uptake among HIV-infected patients using an HIV primary care model.

AIDS research and therapy

Cachay ER, Hill L, Ballard C, Colwell B, Torriani F, Wyles D, Mathews WC.
PMID: 23537147
AIDS Res Ther. 2013 Mar 28;10(1):9. doi: 10.1186/1742-6405-10-9.

BACKGROUND: Access to Hepatitis C (HCV) care is low among HIV-infected individuals, highlighting the need for new models to deliver care for this population.METHODS: Retrospective cohort analysis that compared the number of HIV patients who initiated HCV therapy: hepatology...

Partial characterization of two stable auxotrophic cell strains of Datura innoxia Mill.

Planta

King J, Horsch RB, Savage AD.
PMID: 24306477
Planta. 1980 Oct;149(5):480-4. doi: 10.1007/BF00385752.

A growth analysis of several presumptive "leaky" auxotrophs from Datura innoxia suspension cultures led to the discovery of an adenine-requiring cultures led to the discovery of an adenine-requiring cell strain (Ad1). Both Ad1 and Pn1, a pantothenate-requiring strain isolated...

Effect of sodium bicarbonate and beta-alanine supplementation on maximal sprint swimming.

Journal of the International Society of Sports Nutrition

Mero AA, Hirvonen P, Saarela J, Hulmi JJ, Hoffman JR, Stout JR.
PMID: 24215679
J Int Soc Sports Nutr. 2013 Nov 11;10(1):52. doi: 10.1186/1550-2783-10-52.

BACKGROUND: This study examined the effect of simultaneous supplementation of extracellular buffer sodium bicarbonate (SB) and intracellular buffer beta-alanine (BA) on maximal sprint swimming.METHODS: Thirteen competitive male swimmers completed 4 different treatments (placebo [PL], SB, BA + PL, and...

Liver-kidney transplantation in primary hyperoxaluria type-1: case report and literature review.

International journal of organ transplantation medicine

Siegal D, Su WS, DaBreo D, Puglia M, Gregor L, Gangji AS.
PMID: 25013605
Int J Organ Transplant Med. 2011;2(3):126-32.

Primary hyperoxaluria type-1 (PH1) is a rare inherited autosomal recessive disorder in which a deficiency of the hepatic enzyme alanine-glyoxylate aminotransferase leads to endogenous oxalate overproduction, renal failure, systemic oxalate deposition and death. As hemodialysis provides insufficient oxalate clearance,...

Histopathological differences utilizing the nonalcoholic fatty liver disease activity score criteria in diabetic (type 2 diabetes mellitus) and non-diabetic patients with nonalcoholic fatty liver disease.

World journal of hepatology

Puchakayala BK, Verma S, Kanwar P, Hart J, Sanivarapu RR, Mohanty SR.
PMID: 26557954
World J Hepatol. 2015 Nov 08;7(25):2610-8. doi: 10.4254/wjh.v7.i25.2610.

AIM: To study clinical and histopathological features of nonalcoholic fatty liver disease (NAFLD) in patients with and without type 2 diabetes mellitus (T2DM) using updated nonalcoholic steatohepatitis clinical research network (NASH-CRN) grading system.METHODS: We retrospectively analyzed data of 235...

Amino acids inhibit kynurenic acid formation via suppression of kynurenine uptake or kynurenic acid synthesis in rat brain in vitro.

SpringerPlus

Sekine A, Okamoto M, Kanatani Y, Sano M, Shibata K, Fukuwatari T.
PMID: 25674503
Springerplus. 2015 Feb 01;4:48. doi: 10.1186/s40064-015-0826-9. eCollection 2015.

The tryptophan metabolite, kynurenic acid (KYNA), is a preferential antagonist of the α7 nicotinic acetylcholine receptor at endogenous brain concentrations. Recent studies have suggested that increase of brain KYNA levels is involved in psychiatric disorders such as schizophrenia and...

Cyanidin 3-O-β-Glucoside Ameliorates Ethanol-Induced Acute Liver Injury by Attenuating Oxidative Stress and Apoptosis: The Role of SIRT1/FOXO1 Signaling.

Alcoholism, clinical and experimental research

Liu J, Zhou J, Wu Z, Wang X, Liu L, Yao C.
PMID: 26934204
Alcohol Clin Exp Res. 2016 Mar;40(3):457-66. doi: 10.1111/acer.12982.

BACKGROUND: The aim of this study was to examine the effects of Cyanidin 3-O-β-glucoside (C3G) on ethanol (EtOH)-induced acute liver injury in mice as well as in cultured hepatic cells exposed to EtOH, with a focus on the involvement...

Anti-climacterium effects of pomegranate concentrated solutions in ovariectomized ddY mice.

Experimental and therapeutic medicine

Kang SJ, Choi BR, Kim SH, Yi HY, Park HR, Song CH, Ku SK, Lee YJ.
PMID: 28413464
Exp Ther Med. 2017 Apr;13(4):1249-1266. doi: 10.3892/etm.2017.4109. Epub 2017 Feb 08.

In the present study, the complex anti-climacterium potential of standardized pomegranate concentrated solution (PCS) was investigated using bilateral ovariectomy (OVX) female ddY mice. Changes in body weight and gain during experimental periods, food consumption, serum estradiol levels, total body...

Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

Nature

Sousa CM, Biancur DE, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, Asara JM, Evans RM, Cantley LC, Lyssiotis CA, Kimmelman AC.
PMID: 27706144
Nature. 2016 Dec 01;540(7631):150. doi: 10.1038/nature19851. Epub 2016 Oct 05.

No abstract available.

Showing 1 to 12 of 8701 entries