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Showing 1 to 12 of 4984 entries
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Analysis of biotinylated generation 4 poly (amidoamine)(PAMAM) dendrimer distribution in the rat brain and toxicity in a cellular model of the blood-brain barrier

EPSCoR Research Infrastructure Improvement Program AND Program Evaluation

[No authors listed]
GSID: SEzJ05hIo5AJ
R Hemmer, A Hall, R Spaulding, B Rossow, M Hester… - Molecules, 2013 - mdpi.com

Dendrimers are highly customizable nanopolymers with qualities that make them ideal for drug delivery. The high binding affinity of biotin/avidin provides a useful approach to fluorescently label synthesized dendrimer-conjugates in cells and tissues. In addition, biotin may facilitate delivery...

Evaluation of biotinylated PAMAM dendrimer toxicity in models of the blood brain barrier: a biophysical and cellular approach

EPSCoR Research Infrastructure Improvement Program AND Program Evaluation

[No authors listed]
GSID: og9nyXeY4jEJ
HA Bullen, R Hemmer, A Haskamp, C Cason… - Journal of Biomaterials …, 2011 - scirp.org

The interaction of biotinylated G4 poly (amidoamine)(PAMAM) dendrimer conjugates and G4 PAMAM dendrimers with in vitro models of the blood brain barrier (BBB) was evaluated using Langmuir Blodgett monolayer techniques, atomic force microscopy (AFM) and lactate dehydrogenase measures of...

A view from the bridge.

Bulletin - San Mateo County Dental Society

Kotin B.
PMID: 5218429
Bull San Mateo Cty Dent Soc. 1966 Apr;16(4):2.

No abstract available.

Clinical relevance of the reappraisal of negative hormone receptor expression in breast cancer.

SpringerPlus

Pinto AE, Areia F, Pereira T, Cardoso P, Aparício M, Silva GL, Ferreira MC, André S.
PMID: 24010033
Springerplus. 2013 Aug 09;2:375. doi: 10.1186/2193-1801-2-375. eCollection 2013.

BACKGROUND: Accurate assessment of estrogen (ER) and progesterone (PR) receptors is critical in predicting the response to endocrine therapies in breast cancer.MATERIAL AND METHODS: From a series of 360 patients with breast invasive carcinoma assessed for hormone receptors by...

Expression and clinical significance of IGF-1, IGFBP-3, and IGFBP-7 in serum and lung cancer tissues from patients with non-small cell lung cancer.

OncoTargets and therapy

Wang Z, Wang Z, Liang Z, Liu J, Shi W, Bai P, Lin X, Magaye R, Zhao J.
PMID: 24204158
Onco Targets Ther. 2013 Oct 16;6:1437-44. doi: 10.2147/OTT.S51997. eCollection 2013.

The expression and clinical significance of insulin-like growth factor 1 (IGF-1), insulin-like growth factor binding protein 3 (IGFBP-3), and insulin-like growth factor binding protein 7 (IGFBP-7) were investigated in serum and lung cancer tissues from 57 patients with non-small...

Polymyxin B Induces Apoptosis in Kidney Proximal Tubular Cells.

Antimicrobial agents and chemotherapy

Azad MA, Finnin BA, Poudyal A, Davis K, Li J, Hill PA, Nation RL, Velkov T, Li J.
PMID: 23796937
Antimicrob Agents Chemother. 2013 Sep;57(9):4329-4335. doi: 10.1128/AAC.02587-12. Epub 2013 Jun 24.

The nephrotoxicity of polymyxins is a major dose-limiting factor for treatment of infections caused by multidrug-resistant Gram-negative pathogens. The mechanism(s) of polymyxin-induced nephrotoxicity is not clear. This study aimed to investigate polymyxin B-induced apoptosis in kidney proximal tubular cells....

Development and characterization of microsatellite loci for the Moroccan endemic endangered species Argania spinosa (Sapotaceae).

Applications in plant sciences

El Bahloul Y, Dauchot N, Machtoun I, Gaboun F, Van Cutsem P.
PMID: 25202614
Appl Plant Sci. 2014 Mar 31;2(4). doi: 10.3732/apps.1300071. eCollection 2014 Apr.

PREMISE OF THE STUDY: Microsatellite loci were developed for the Moroccan endemic endangered species Argania spinosa with a combination of a typical library enrichment procedure and a 454 GS FLX Titanium-based high-throughput sequencing approach. •METHODS AND RESULTS: A genomic...

Development of 16 microsatellite markers within the Camassia (Agavaceae) species complex and amplification in related taxa.

Applications in plant sciences

Culley TM, Leng JF, Kephart SR, Cartieri FJ, Theiss KE.
PMID: 25202572
Appl Plant Sci. 2013 Jul 22;1(8). doi: 10.3732/apps.1300001. eCollection 2013 Aug.

PREMISE OF THE STUDY: The North American genus Camassia is an ecologically important group whose variability and evolution are little understood, being influenced by hybridization and geographic isolation. We developed microsatellite markers to investigate patterns of gene flow, population...

Integration of Faradaic electrochemical impedance spectroscopy into a scalable surface plasmon biosensor for in tandem detection.

Optics express

Hong B, Sun A, Pang L, Venkatesh AG, Hall D, Fainman Y.
PMID: 26698504
Opt Express. 2015 Nov 16;23(23):30237-49. doi: 10.1364/OE.23.030237.

We present an integrated label-free biosensor based on surface plasmon resonance (SPR) and Faradaic electrochemical impedance spectroscopy (f-EIS) sensing modalities, for the simultaneous detection of biological analytes. Analyte detection is based on the angular spectroscopy of surface plasmon resonance...

Efficient Chemoenzymatic Synthesis of an N-glycan Isomer Library.

Chemical science

Li L, Liu Y, Ma C, Qu J, Calderon AD, Wu B, Wei N, Wang X, Guo Y, Xiao Z, Song J, Sugiarto G, Li Y, Yu H, Chen X, Wang PG.
PMID: 26417422
Chem Sci. 2015 Oct 01;6(10):5652-5661. doi: 10.1039/C5SC02025E. Epub 2015 Jun 23.

Quantification, characterization and biofunctional studies of N-glycans on proteins remain challenging tasks due to complexity, diversity and low abundance of these glycans. The availability of structurally defined N-glycans (especially isomers) libraries is essential to help on solving these tasks....

Towards the development of an enzyme replacement therapy for the metabolic disorder propionic acidemia.

Molecular genetics and metabolism reports

Darvish-Damavandi M, Ho HK, Kang TS.
PMID: 27504265
Mol Genet Metab Rep. 2016 Jul 27;8:51-60. doi: 10.1016/j.ymgmr.2016.06.009. eCollection 2016 Sep.

Propionic acidemia (PA) is a life-threatening disease caused by the deficiency of a mitochondrial biotin-dependent enzyme known as propionyl coenzyme-A carboxylase (PCC). This enzyme is responsible for degrading the metabolic intermediate, propionyl coenzyme-A (PP-CoA), derived from multiple metabolic pathways....

Comparing Influenza Positivity Rates by Real-Time RT-PCR, Elisa and Viral Culture Methods in Côte D'Ivoire, West Africa, in 2009.

African journal of infectious diseases

Nzussouo NT, Kadjo HA, Coulibaly D, Ekaza E, Kouakou B, N'Golo DC, Tempia S, Davis R, Dosso M, Thompson M.
PMID: 28451079
Afr J Infect Dis. 2013 Aug 09;7(2):31-35. doi: 10.4314/ajid.v7i2.3.

Detection of circulating influenza strains is a key public health concern especially in limited-resource settings where diagnosis capabilities remain a challenge. As part of multi-site surveillance in Côte d'Ivoire during the 2009 influenza A(H1N1) pandemic, we had the opportunity...

Showing 1 to 12 of 4984 entries