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Showing 1 to 12 of 16 entries
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Hypoxanthine phosphoribosyltransferase activity in bovine embryos during the early embryonic development.

Theriogenology

Kita M, Imai H.
PMID: 16727321
Theriogenology. 1993 Aug;40(2):357-64. doi: 10.1016/0093-691x(93)90273-8.

The activity of hypoxanthine phosphoribosyltransferase (HPRT) was determined in the bovine embryo during early embryonic development. Microassay, using [(3)H] hypoxanthine, was improved to measure enzyme activity in the embryonic extract. This activity depended on the reaction time and the...

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Kita M, Imai H. Hypoxanthine phosphoribosyltransferase activity in bovine embryos during the early embryonic development. Theriogenology. 1993;40(2):357-64doi: 10.1016/0093-691x(93)90273-8.
Kita, M., & Imai, H. (1993). Hypoxanthine phosphoribosyltransferase activity in bovine embryos during the early embryonic development. Theriogenology, 40(2), 357-64. https://doi.org/10.1016/0093-691x(93)90273-8
Kita, M, and Imai, H. "Hypoxanthine phosphoribosyltransferase activity in bovine embryos during the early embryonic development." Theriogenology vol. 40,2 (1993): 357-64. doi: https://doi.org/10.1016/0093-691x(93)90273-8
Kita M, Imai H. Hypoxanthine phosphoribosyltransferase activity in bovine embryos during the early embryonic development. Theriogenology. 1993 Aug;40(2):357-64. doi: 10.1016/0093-691x(93)90273-8. PMID: 16727321.
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Purine-phosphoribosyltransferase activities in rat and mouse tissues and in Ehrlich ascites-tumour cells.

The Biochemical journal

Murray AW.
PMID: 16742414
Biochem J. 1966 Sep;100(3):664-70. doi: 10.1042/bj1000664.

1. The activities of adenine phosphoribosyltransferase and hypoxanthine phosphoribosyltransferase in extracts of rat and mouse liver, brain, spleen, heart and kidney, of rat bone marrow and of Ehrlich ascites-tumour cells have been measured. The specific activity of adenine phosphoribosyltransferase...

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Murray AW. Purine-phosphoribosyltransferase activities in rat and mouse tissues and in Ehrlich ascites-tumour cells. Biochem J. 1966;100(3):664-70doi: 10.1042/bj1000664.
Murray, A. W. (1966). Purine-phosphoribosyltransferase activities in rat and mouse tissues and in Ehrlich ascites-tumour cells. The Biochemical journal, 100(3), 664-70. https://doi.org/10.1042/bj1000664
Murray, A W. "Purine-phosphoribosyltransferase activities in rat and mouse tissues and in Ehrlich ascites-tumour cells." The Biochemical journal vol. 100,3 (1966): 664-70. doi: https://doi.org/10.1042/bj1000664
Murray AW. Purine-phosphoribosyltransferase activities in rat and mouse tissues and in Ehrlich ascites-tumour cells. Biochem J. 1966 Sep;100(3):664-70. doi: 10.1042/bj1000664. PMID: 16742414; PMCID: PMC1265199.
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Technical Report: A Simple and Robust Real-Time Quantitative PCR Method for the Detection of Radiation-Induced Multiple Exon Deletions of the Human HPRT Gene.

Radiation research

Kawamura K, Suzuki K, Mitsutake N.
PMID: 34143221
Radiat Res. 2021 Jun 18; doi: 10.1667/RADE-21-00047.1. Epub 2021 Jun 18.

The hypoxanthine-phosphoribosyltransferase (HPRT) mutation assay has been widely used to investigate gene mutations induced by radiation. Here, we developed a novel method detecting deletions of multiple exons of the HPRT gene based on real-time quantitative PCR (qPCR). Immortalized normal...

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Kawamura K, Suzuki K, Mitsutake N. Technical Report: A Simple and Robust Real-Time Quantitative PCR Method for the Detection of Radiation-Induced Multiple Exon Deletions of the Human HPRT Gene. Radiat Res. 2021;doi: 10.1667/RADE-21-00047.1.
Kawamura, K., Suzuki, K., & Mitsutake, N. (2021). Technical Report: A Simple and Robust Real-Time Quantitative PCR Method for the Detection of Radiation-Induced Multiple Exon Deletions of the Human HPRT Gene. Radiation research, . https://doi.org/10.1667/RADE-21-00047.1
Kawamura, Kasumi, et al. "Technical Report: A Simple and Robust Real-Time Quantitative PCR Method for the Detection of Radiation-Induced Multiple Exon Deletions of the Human HPRT Gene." Radiation research vol. (2021). doi: https://doi.org/10.1667/RADE-21-00047.1
Kawamura K, Suzuki K, Mitsutake N. Technical Report: A Simple and Robust Real-Time Quantitative PCR Method for the Detection of Radiation-Induced Multiple Exon Deletions of the Human HPRT Gene. Radiat Res. 2021 Jun 18; doi: 10.1667/RADE-21-00047.1. Epub 2021 Jun 18. PMID: 34143221.
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Potential molecular link between the β-amyloid precursor protein (APP) and hypoxanthine-guanine phosphoribosyltransferase (HGprt) enzyme in Lesch-Nyhan disease and cancer.

AIMS neuroscience

Nguyen KV.
PMID: 34877405
AIMS Neurosci. 2021 Oct 28;8(4):548-557. doi: 10.3934/Neuroscience.2021030. eCollection 2021.

Lesch-Nyhan disease (LND) is a rare X-linked inherited neurogenetic disorders of purine metabolic in which the cytoplasmic enzyme, hypoxanthine-guanine phosphoribosyltransferase (HGprt) is defective. Despite having been characterized over 60 years ago, however, up to now, there is no satisfactory...

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Nguyen KV. Potential molecular link between the β-amyloid precursor protein (APP) and hypoxanthine-guanine phosphoribosyltransferase (HGprt) enzyme in Lesch-Nyhan disease and cancer. AIMS Neurosci. 2021;8(4):548-557doi: 10.3934/Neuroscience.2021030.
Nguyen, K. V. (2021). Potential molecular link between the β-amyloid precursor protein (APP) and hypoxanthine-guanine phosphoribosyltransferase (HGprt) enzyme in Lesch-Nyhan disease and cancer. AIMS neuroscience, 8(4), 548-557. https://doi.org/10.3934/Neuroscience.2021030
Nguyen, Khue Vu. "Potential molecular link between the β-amyloid precursor protein (APP) and hypoxanthine-guanine phosphoribosyltransferase (HGprt) enzyme in Lesch-Nyhan disease and cancer." AIMS neuroscience vol. 8,4 (2021): 548-557. doi: https://doi.org/10.3934/Neuroscience.2021030
Nguyen KV. Potential molecular link between the β-amyloid precursor protein (APP) and hypoxanthine-guanine phosphoribosyltransferase (HGprt) enzyme in Lesch-Nyhan disease and cancer. AIMS Neurosci. 2021 Oct 28;8(4):548-557. doi: 10.3934/Neuroscience.2021030. eCollection 2021. PMID: 34877405; PMCID: PMC8611187.
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Evaluation of an Hprt-Luciferase Reporter Gene on a Mammalian Artificial Chromosome in Response to Cytotoxicity.

Yonago acta medica

Endo T, Noda N, Kuromi Y, Kokura K, Kazuki Y, Oshimura M, Ohbayashi T.
PMID: 27493490
Yonago Acta Med. 2016 Jun 29;59(2):174-82. eCollection 2016 Jun.

BACKGROUND: Hypoxanthine guanine phosphoribosyltransferase (Hprt) is known as a house-keeping gene, and has been used as an internal control for real-time quantitative RT-PCR and various other methods of gene expression analysis. To evaluate the Hprt mRNA levels as a...

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Endo T, Noda N, Kuromi Y, et al. Evaluation of an Hprt-Luciferase Reporter Gene on a Mammalian Artificial Chromosome in Response to Cytotoxicity. Yonago Acta Med. 2016;59(2):174-82
Endo, T., Noda, N., Kuromi, Y., Kokura, K., Kazuki, Y., Oshimura, M., & Ohbayashi, T. (2016). Evaluation of an Hprt-Luciferase Reporter Gene on a Mammalian Artificial Chromosome in Response to Cytotoxicity. Yonago acta medica, 59(2), 174-82.
Endo, Takeshi, et al. "Evaluation of an Hprt-Luciferase Reporter Gene on a Mammalian Artificial Chromosome in Response to Cytotoxicity." Yonago acta medica vol. 59,2 (2016): 174-82.
Endo T, Noda N, Kuromi Y, Kokura K, Kazuki Y, Oshimura M, Ohbayashi T. Evaluation of an Hprt-Luciferase Reporter Gene on a Mammalian Artificial Chromosome in Response to Cytotoxicity. Yonago Acta Med. 2016 Jun 29;59(2):174-82. eCollection 2016 Jun. PMID: 27493490; PMCID: PMC4973025.
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Identification of stable reference genes for lipopolysaccharide-stimulated macrophage gene expression studies.

Biology methods & protocols

Kalagara R, Gao W, Glenn HL, Ziegler C, Belmont L, Meldrum DR.
PMID: 32161782
Biol Methods Protoc. 2016 Dec 27;1(1):bpw005. doi: 10.1093/biomethods/bpw005. eCollection 2016 Mar.

Gene expression studies which utilize lipopolysaccharide (LPS)-stimulated macrophages to model immune signaling are widely used for elucidating the mechanisms of inflammation-related disease. When expression levels of target genes are quantified using Real-Time quantitative Reverse Transcription Polymerase Chain Reaction (qRT-PCR),...

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Kalagara R, Gao W, Glenn HL, et al. Identification of stable reference genes for lipopolysaccharide-stimulated macrophage gene expression studies. Biol Methods Protoc. 2016;1(1):bpw005doi: 10.1093/biomethods/bpw005.
Kalagara, R., Gao, W., Glenn, H. L., Ziegler, C., Belmont, L., & Meldrum, D. R. (2016). Identification of stable reference genes for lipopolysaccharide-stimulated macrophage gene expression studies. Biology methods & protocols, 1(1), bpw005. https://doi.org/10.1093/biomethods/bpw005
Kalagara, Roshini, et al. "Identification of stable reference genes for lipopolysaccharide-stimulated macrophage gene expression studies." Biology methods & protocols vol. 1,1 (2016): bpw005. doi: https://doi.org/10.1093/biomethods/bpw005
Kalagara R, Gao W, Glenn HL, Ziegler C, Belmont L, Meldrum DR. Identification of stable reference genes for lipopolysaccharide-stimulated macrophage gene expression studies. Biol Methods Protoc. 2016 Dec 27;1(1):bpw005. doi: 10.1093/biomethods/bpw005. eCollection 2016 Mar. PMID: 32161782; PMCID: PMC6994071.
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Thermophilic phosphoribosyltransferases .

Beilstein journal of organic chemistry

Fateev IV, Sinitsina EV, Bikanasova AU, Kostromina MA, Tuzova ES, Esipova LV, Muravyova TI, Kayushin AL, Konstantinova ID, Esipov RS.
PMID: 30643587
Beilstein J Org Chem. 2018 Dec 21;14:3098-3105. doi: 10.3762/bjoc.14.289. eCollection 2018.

Phosphoribosyltransferases are the tools that allow the synthesis of nucleotide analogues using multi-enzymatic cascades. The recombinant adenine phosphoribosyltransferase (

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Fateev IV, Sinitsina EV, Bikanasova AU, et al. Thermophilic phosphoribosyltransferases . Beilstein J Org Chem. 2018;14:3098-3105doi: 10.3762/bjoc.14.289.
Fateev, I. V., Sinitsina, E. V., Bikanasova, A. U., Kostromina, M. A., Tuzova, E. S., Esipova, L. V., Muravyova, T. I., Kayushin, A. L., Konstantinova, I. D., & Esipov, R. S. (2018). Thermophilic phosphoribosyltransferases . Beilstein journal of organic chemistry, 143098-3105. https://doi.org/10.3762/bjoc.14.289
Fateev, Ilja V, et al. "Thermophilic phosphoribosyltransferases ." Beilstein journal of organic chemistry vol. 14 (2018): 3098-3105. doi: https://doi.org/10.3762/bjoc.14.289
Fateev IV, Sinitsina EV, Bikanasova AU, Kostromina MA, Tuzova ES, Esipova LV, Muravyova TI, Kayushin AL, Konstantinova ID, Esipov RS. Thermophilic phosphoribosyltransferases . Beilstein J Org Chem. 2018 Dec 21;14:3098-3105. doi: 10.3762/bjoc.14.289. eCollection 2018. PMID: 30643587; PMCID: PMC6317416.
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Evaluation and validation of suitable reference genes for reverse transcription-quantitative polymerase chain reaction studies in cholangiocarcinoma patients and cell lines.

Oncology letters

Yang J, Yang Q, Yu S, Zhang X.
PMID: 27073537
Oncol Lett. 2016 Apr;11(4):2673-2681. doi: 10.3892/ol.2016.4232. Epub 2016 Feb 17.

Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) has become a frequently used method in gene expression studies. The relative quantification method is an important and common method for the evaluation of RT-qPCR data. One of the key requirements of this...

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Yang J, Yang Q, Yu S, et al. Evaluation and validation of suitable reference genes for reverse transcription-quantitative polymerase chain reaction studies in cholangiocarcinoma patients and cell lines. Oncol Lett. 2016;11(4):2673-2681doi: 10.3892/ol.2016.4232.
Yang, J., Yang, Q., Yu, S., & Zhang, X. (2016). Evaluation and validation of suitable reference genes for reverse transcription-quantitative polymerase chain reaction studies in cholangiocarcinoma patients and cell lines. Oncology letters, 11(4), 2673-2681. https://doi.org/10.3892/ol.2016.4232
Yang, Jinghui, et al. "Evaluation and validation of suitable reference genes for reverse transcription-quantitative polymerase chain reaction studies in cholangiocarcinoma patients and cell lines." Oncology letters vol. 11,4 (2016): 2673-2681. doi: https://doi.org/10.3892/ol.2016.4232
Yang J, Yang Q, Yu S, Zhang X. Evaluation and validation of suitable reference genes for reverse transcription-quantitative polymerase chain reaction studies in cholangiocarcinoma patients and cell lines. Oncol Lett. 2016 Apr;11(4):2673-2681. doi: 10.3892/ol.2016.4232. Epub 2016 Feb 17. PMID: 27073537; PMCID: PMC4812119.
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A deficiency of hypoxanthine phosphoribosyltransferase in a sycamore callus resistant to azaguanine.

Planta

Bright SW, Northcote DH.
PMID: 24436026
Planta. 1975 Jan;123(1):79-89. doi: 10.1007/BF00388062.

Sycamore (Acer pseudoplatanus L.) calluses resistant to azaguanine were isolated after mutagenesis with nitrosoguanidine. One callus SNC61 was highly variable in its growth on 10 μg/ml azaguanine and it was concluded that its resistance was not due to a...

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Bright SW, Northcote DH. A deficiency of hypoxanthine phosphoribosyltransferase in a sycamore callus resistant to azaguanine. Planta. 1975;123(1):79-89doi: 10.1007/BF00388062.
Bright, S. W., & Northcote, D. H. (1975). A deficiency of hypoxanthine phosphoribosyltransferase in a sycamore callus resistant to azaguanine. Planta, 123(1), 79-89. https://doi.org/10.1007/BF00388062
Bright, S W, and Northcote, D H. "A deficiency of hypoxanthine phosphoribosyltransferase in a sycamore callus resistant to azaguanine." Planta vol. 123,1 (1975): 79-89. doi: https://doi.org/10.1007/BF00388062
Bright SW, Northcote DH. A deficiency of hypoxanthine phosphoribosyltransferase in a sycamore callus resistant to azaguanine. Planta. 1975 Jan;123(1):79-89. doi: 10.1007/BF00388062. PMID: 24436026.
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Evaluation of housekeeping genes for quantitative gene expression analysis in the equine kidney.

Journal of equine science

Azarpeykan S, Dittmer KE.
PMID: 27974876
J Equine Sci. 2016;27(4):165-168. doi: 10.1294/jes.27.165. Epub 2016 Dec 15.

Housekeeping genes (HKGs) are used as internal controls for normalising and calculating the relative expression of target genes in RT-qPCR experiments. There is no unique universal HKG and HKGs vary among organisms and tissues, so this study aimed to...

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Azarpeykan S, Dittmer KE. Evaluation of housekeeping genes for quantitative gene expression analysis in the equine kidney. J Equine Sci. 2016;27(4):165-168doi: 10.1294/jes.27.165.
Azarpeykan, S., & Dittmer, K. E. (2016). Evaluation of housekeeping genes for quantitative gene expression analysis in the equine kidney. Journal of equine science, 27(4), 165-168. https://doi.org/10.1294/jes.27.165
Azarpeykan, Sara, and Dittmer, Keren E. "Evaluation of housekeeping genes for quantitative gene expression analysis in the equine kidney." Journal of equine science vol. 27,4 (2016): 165-168. doi: https://doi.org/10.1294/jes.27.165
Azarpeykan S, Dittmer KE. Evaluation of housekeeping genes for quantitative gene expression analysis in the equine kidney. J Equine Sci. 2016;27(4):165-168. doi: 10.1294/jes.27.165. Epub 2016 Dec 15. PMID: 27974876; PMCID: PMC5155135.
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Overexpression of HPRT1 is associated with poor prognosis in head and neck squamous cell carcinoma.

FEBS open bio

Ahmadi M, Eftekhari Kenzerki M, Akrami SM, Pashangzadeh S, Hajiesmaeili F, Rahnavard S, Habibipour L, Saffarzadeh N, Mousavi P.
PMID: 34231338
FEBS Open Bio. 2021 Sep;11(9):2525-2540. doi: 10.1002/2211-5463.13250. Epub 2021 Aug 04.

Hypoxanthine phosphoribosyltransferase (HPRT1), as a salvage pathway enzyme, plays a crucial role in modulating the cell cycle and has been reported to be overexpressed in multiple cancers. Nevertheless, the relationship between the HPRT1 gene and head and neck squamous...

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Ahmadi M, Eftekhari Kenzerki M, Akrami SM, et al. Overexpression of HPRT1 is associated with poor prognosis in head and neck squamous cell carcinoma. FEBS Open Bio. 2021;11(9):2525-2540doi: 10.1002/2211-5463.13250.
Ahmadi, M., Eftekhari Kenzerki, M., Akrami, S. M., Pashangzadeh, S., Hajiesmaeili, F., Rahnavard, S., Habibipour, L., Saffarzadeh, N., & Mousavi, P. (2021). Overexpression of HPRT1 is associated with poor prognosis in head and neck squamous cell carcinoma. FEBS open bio, 11(9), 2525-2540. https://doi.org/10.1002/2211-5463.13250
Ahmadi, Mohsen, et al. "Overexpression of HPRT1 is associated with poor prognosis in head and neck squamous cell carcinoma." FEBS open bio vol. 11,9 (2021): 2525-2540. doi: https://doi.org/10.1002/2211-5463.13250
Ahmadi M, Eftekhari Kenzerki M, Akrami SM, Pashangzadeh S, Hajiesmaeili F, Rahnavard S, Habibipour L, Saffarzadeh N, Mousavi P. Overexpression of HPRT1 is associated with poor prognosis in head and neck squamous cell carcinoma. FEBS Open Bio. 2021 Sep;11(9):2525-2540. doi: 10.1002/2211-5463.13250. Epub 2021 Aug 04. PMID: 34231338; PMCID: PMC8409317.
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Overexpression of HPRT1 is associated with poor prognosis in head and neck squamous cell carcinoma.

FEBS open bio

Ahmadi M, Eftekhari Kenzerki M, Akrami SM, Pashangzadeh S, Hajiesmaeili F, Rahnavard S, Habibipour L, Saffarzadeh N, Mousavi P.
PMID: 34231338
FEBS Open Bio. 2021 Sep;11(9):2525-2540. doi: 10.1002/2211-5463.13250. Epub 2021 Aug 04.

Hypoxanthine phosphoribosyltransferase (HPRT1), as a salvage pathway enzyme, plays a crucial role in modulating the cell cycle and has been reported to be overexpressed in multiple cancers. Nevertheless, the relationship between the HPRT1 gene and head and neck squamous...

Cite
Ahmadi M, Eftekhari Kenzerki M, Akrami SM, et al. Overexpression of HPRT1 is associated with poor prognosis in head and neck squamous cell carcinoma. FEBS Open Bio. 2021;11(9):2525-2540doi: 10.1002/2211-5463.13250.
Ahmadi, M., Eftekhari Kenzerki, M., Akrami, S. M., Pashangzadeh, S., Hajiesmaeili, F., Rahnavard, S., Habibipour, L., Saffarzadeh, N., & Mousavi, P. (2021). Overexpression of HPRT1 is associated with poor prognosis in head and neck squamous cell carcinoma. FEBS open bio, 11(9), 2525-2540. https://doi.org/10.1002/2211-5463.13250
Ahmadi, Mohsen, et al. "Overexpression of HPRT1 is associated with poor prognosis in head and neck squamous cell carcinoma." FEBS open bio vol. 11,9 (2021): 2525-2540. doi: https://doi.org/10.1002/2211-5463.13250
Ahmadi M, Eftekhari Kenzerki M, Akrami SM, Pashangzadeh S, Hajiesmaeili F, Rahnavard S, Habibipour L, Saffarzadeh N, Mousavi P. Overexpression of HPRT1 is associated with poor prognosis in head and neck squamous cell carcinoma. FEBS Open Bio. 2021 Sep;11(9):2525-2540. doi: 10.1002/2211-5463.13250. Epub 2021 Aug 04. PMID: 34231338; PMCID: PMC8409317.
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Showing 1 to 12 of 16 entries