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Showing 1 to 12 of 86 entries
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Involvement of CNS cholinergic systems in alcohol drinking of P rats.

Addiction biology

Katner SN, McBRIDE WJ, Lumeng L, Li TK, Murphy JM.
PMID: 26735639
Addict Biol. 1997 Apr;2(2):215-23. doi: 10.1080/13556219772769.

Experiments were undertaken to determine if CNS muscarinic- and nicotinic-cholinergic receptors are involved in regulating alcohol drinking of rats from the selectively-bred alcohol-preferring P line. Intracerebroventricular (i.c.v.) drug infusions were administered into the lateral ventricle of female P rats...

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Katner SN, McBRIDE WJ, Lumeng L, et al. Involvement of CNS cholinergic systems in alcohol drinking of P rats. Addict Biol. 1997;2(2):215-23doi: 10.1080/13556219772769.
Katner, S. N., McBRIDE, W. J., Lumeng, L., Li, T. K., & Murphy, J. M. (1997). Involvement of CNS cholinergic systems in alcohol drinking of P rats. Addiction biology, 2(2), 215-23. https://doi.org/10.1080/13556219772769
Katner, S N, et al. "Involvement of CNS cholinergic systems in alcohol drinking of P rats." Addiction biology vol. 2,2 (1997): 215-23. doi: https://doi.org/10.1080/13556219772769
Katner SN, McBRIDE WJ, Lumeng L, Li TK, Murphy JM. Involvement of CNS cholinergic systems in alcohol drinking of P rats. Addict Biol. 1997 Apr;2(2):215-23. doi: 10.1080/13556219772769. PMID: 26735639.
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Subthalamic and Cortical Local Field Potentials Associated with Pilocarpine-Induced Oral Tremor in the Rat.

Frontiers in behavioral neuroscience

Long LL, Podurgiel SJ, Haque AF, Errante EL, Chrobak JJ, Salamone JD.
PMID: 27378874
Front Behav Neurosci. 2016 Jun 17;10:123. doi: 10.3389/fnbeh.2016.00123. eCollection 2016.

Tremulous jaw movements (TJMs) are rapid vertical deflections of the lower jaw that resemble chewing but are not directed at any particular stimulus. In rodents, TJMs are induced by neurochemical conditions that parallel those seen in human Parkinsonism, including...

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Long LL, Podurgiel SJ, Haque AF, et al. Subthalamic and Cortical Local Field Potentials Associated with Pilocarpine-Induced Oral Tremor in the Rat. Front Behav Neurosci. 2016;10:123doi: 10.3389/fnbeh.2016.00123.
Long, L. L., Podurgiel, S. J., Haque, A. F., Errante, E. L., Chrobak, J. J., & Salamone, J. D. (2016). Subthalamic and Cortical Local Field Potentials Associated with Pilocarpine-Induced Oral Tremor in the Rat. Frontiers in behavioral neuroscience, 10123. https://doi.org/10.3389/fnbeh.2016.00123
Long, Lauren L, et al. "Subthalamic and Cortical Local Field Potentials Associated with Pilocarpine-Induced Oral Tremor in the Rat." Frontiers in behavioral neuroscience vol. 10 (2016): 123. doi: https://doi.org/10.3389/fnbeh.2016.00123
Long LL, Podurgiel SJ, Haque AF, Errante EL, Chrobak JJ, Salamone JD. Subthalamic and Cortical Local Field Potentials Associated with Pilocarpine-Induced Oral Tremor in the Rat. Front Behav Neurosci. 2016 Jun 17;10:123. doi: 10.3389/fnbeh.2016.00123. eCollection 2016. PMID: 27378874; PMCID: PMC4911403.
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Factors affecting medication discontinuation in patients with overactive bladder symptoms.

Obstetrics & gynecology science

Shim EJ, Yoo EH, Kim YM, Kim D.
PMID: 26623416
Obstet Gynecol Sci. 2015 Nov;58(6):507-13. doi: 10.5468/ogs.2015.58.6.507. Epub 2015 Nov 16.

OBJECTIVE: To find out the factors affecting medication discontinuation in patients with overactive bladder (OAB) symptoms.METHODS: The clinical data of 125 patients with OAB symptoms who had taken antimuscarinics and behavioral therapy were retrospectively reviewed. Antimuscarinics related outcomes were...

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Shim EJ, Yoo EH, Kim YM, et al. Factors affecting medication discontinuation in patients with overactive bladder symptoms. Obstet Gynecol Sci. 2015;58(6):507-13doi: 10.5468/ogs.2015.58.6.507.
Shim, E. J., Yoo, E. H., Kim, Y. M., & Kim, D. (2015). Factors affecting medication discontinuation in patients with overactive bladder symptoms. Obstetrics & gynecology science, 58(6), 507-13. https://doi.org/10.5468/ogs.2015.58.6.507
Shim, Eun-Jung, et al. "Factors affecting medication discontinuation in patients with overactive bladder symptoms." Obstetrics & gynecology science vol. 58,6 (2015): 507-13. doi: https://doi.org/10.5468/ogs.2015.58.6.507
Shim EJ, Yoo EH, Kim YM, Kim D. Factors affecting medication discontinuation in patients with overactive bladder symptoms. Obstet Gynecol Sci. 2015 Nov;58(6):507-13. doi: 10.5468/ogs.2015.58.6.507. Epub 2015 Nov 16. PMID: 26623416; PMCID: PMC4663230.
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Associations between different measures of anticholinergic drug exposure and Barthel Index in older hospitalized patients.

Therapeutic advances in drug safety

Bostock CV, Soiza RL, Mangoni AA.
PMID: 25114784
Ther Adv Drug Saf. 2013 Dec;4(6):235-45. doi: 10.1177/2042098613500689.

OBJECTIVE: To compare associations between four measures of anticholinergic exposure (anticholinergic risk scale, ARS; anticholinergic drug burden, DBAC; number and use versus no use of anticholinergic drugs), Barthel Index (BI, physical function) and Abbreviated Mental Test (AMT, cognitive function)...

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Bostock CV, Soiza RL, Mangoni AA. Associations between different measures of anticholinergic drug exposure and Barthel Index in older hospitalized patients. Ther Adv Drug Saf. 2013;4(6):235-45doi: 10.1177/2042098613500689.
Bostock, C. V., Soiza, R. L., & Mangoni, A. A. (2013). Associations between different measures of anticholinergic drug exposure and Barthel Index in older hospitalized patients. Therapeutic advances in drug safety, 4(6), 235-45. https://doi.org/10.1177/2042098613500689
Bostock, Clare V, et al. "Associations between different measures of anticholinergic drug exposure and Barthel Index in older hospitalized patients." Therapeutic advances in drug safety vol. 4,6 (2013): 235-45. doi: https://doi.org/10.1177/2042098613500689
Bostock CV, Soiza RL, Mangoni AA. Associations between different measures of anticholinergic drug exposure and Barthel Index in older hospitalized patients. Ther Adv Drug Saf. 2013 Dec;4(6):235-45. doi: 10.1177/2042098613500689. PMID: 25114784; PMCID: PMC4125311.
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Effects of selective antagonism or depletion of the cholinergic system on visual discrimination performance in rats.

Behavioural pharmacology

Drinkenburg WH, Sondag HN, Coenders CJ, Andrews JS, Vossen JM.
PMID: 11224372
Behav Pharmacol. 1995 Nov;6(7):695-702.

A two-lever simultaneous visual discrimination task was used to study the effects on performance in Long-Evans rats of the muscarinic antagonists scopolamine (0.0125, 0.05, 0.2 and 0.8mg/kg s.c.), the M(1) antagonist pirenzepine, the M(2) antagonist AF-DX 116, the M(3)...

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Drinkenburg WH, Sondag HN, Coenders CJ, et al. Effects of selective antagonism or depletion of the cholinergic system on visual discrimination performance in rats. Behav Pharmacol. 1995;6(7):695-702
Drinkenburg, W. H., Sondag, H. N., Coenders, C. J., Andrews, J. S., & Vossen, J. M. (1995). Effects of selective antagonism or depletion of the cholinergic system on visual discrimination performance in rats. Behavioural pharmacology, 6(7), 695-702.
Drinkenburg, W.H.I.M., et al. "Effects of selective antagonism or depletion of the cholinergic system on visual discrimination performance in rats." Behavioural pharmacology vol. 6,7 (1995): 695-702.
Drinkenburg WH, Sondag HN, Coenders CJ, Andrews JS, Vossen JM. Effects of selective antagonism or depletion of the cholinergic system on visual discrimination performance in rats. Behav Pharmacol. 1995 Nov;6(7):695-702. PMID: 11224372.
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Muscarinic autoreceptors are differentially affected by selective muscarinic antagonists in rat hippocampus.

Neurochemistry international

Gulya K, Budai D, Kása P.
PMID: 20504477
Neurochem Int. 1989;15(2):153-6. doi: 10.1016/0197-0186(89)90094-6.

The effects of atropine, pirenzepine and AF-DX 116 on the high K(+)-evoked release of endogenous ACh from rat hippocampal slices were compared. As expected, atropine in concentrations of 10(?5) and 10(?6)M increased the release of acetylcholine, to 128 and...

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Gulya K, Budai D, Kása P. Muscarinic autoreceptors are differentially affected by selective muscarinic antagonists in rat hippocampus. Neurochem Int. 1989;15(2):153-6doi: 10.1016/0197-0186(89)90094-6.
Gulya, K., Budai, D., & Kása, P. (1989). Muscarinic autoreceptors are differentially affected by selective muscarinic antagonists in rat hippocampus. Neurochemistry international, 15(2), 153-6. https://doi.org/10.1016/0197-0186(89)90094-6
Gulya, K, et al. "Muscarinic autoreceptors are differentially affected by selective muscarinic antagonists in rat hippocampus." Neurochemistry international vol. 15,2 (1989): 153-6. doi: https://doi.org/10.1016/0197-0186(89)90094-6
Gulya K, Budai D, Kása P. Muscarinic autoreceptors are differentially affected by selective muscarinic antagonists in rat hippocampus. Neurochem Int. 1989;15(2):153-6. doi: 10.1016/0197-0186(89)90094-6. PMID: 20504477.
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Pharmacotherapies for chronic obstructive pulmonary disease: a multiple treatment comparison meta-analysis.

Clinical epidemiology

Mills EJ, Druyts E, Ghement I, Puhan MA.
PMID: 21487451
Clin Epidemiol. 2011 Mar 28;3:107-29. doi: 10.2147/CLEP.S16235.

BACKGROUND: Most patients with moderate and severe chronic obstructive pulmonary disease (COPD) receive long-acting bronchodilators (LABA) for symptom control. It is, however, unclear if and what drug treatments should be added to LABAs to reduce exacerbations, which is an...

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Mills EJ, Druyts E, Ghement I, et al. Pharmacotherapies for chronic obstructive pulmonary disease: a multiple treatment comparison meta-analysis. Clin Epidemiol. 2011;3:107-29doi: 10.2147/CLEP.S16235.
Mills, E. J., Druyts, E., Ghement, I., & Puhan, M. A. (2011). Pharmacotherapies for chronic obstructive pulmonary disease: a multiple treatment comparison meta-analysis. Clinical epidemiology, 3107-29. https://doi.org/10.2147/CLEP.S16235
Mills, Edward J, et al. "Pharmacotherapies for chronic obstructive pulmonary disease: a multiple treatment comparison meta-analysis." Clinical epidemiology vol. 3 (2011): 107-29. doi: https://doi.org/10.2147/CLEP.S16235
Mills EJ, Druyts E, Ghement I, Puhan MA. Pharmacotherapies for chronic obstructive pulmonary disease: a multiple treatment comparison meta-analysis. Clin Epidemiol. 2011 Mar 28;3:107-29. doi: 10.2147/CLEP.S16235. PMID: 21487451; PMCID: PMC3072154.
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Pharmacotherapies for COPD.

Clinical medicine insights. Circulatory, respiratory and pulmonary medicine

Ejiofor S, Turner AM.
PMID: 23700381
Clin Med Insights Circ Respir Pulm Med. 2013 Apr 25;7:17-34. doi: 10.4137/CCRPM.S7211. Print 2013.

This review article summarizes the main treatments for chronic obstructive pulmonary disease, their mechanisms, and the key evidence from trials supporting their use. Drug classes covered were short acting beta agonists (SABA), short acting muscarinic antagonists (SAMA), long acting...

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Ejiofor S, Turner AM. Pharmacotherapies for COPD. Clin Med Insights Circ Respir Pulm Med. 2013;7:17-34doi: 10.4137/CCRPM.S7211.
Ejiofor, S., & Turner, A. M. (2013). Pharmacotherapies for COPD. Clinical medicine insights. Circulatory, respiratory and pulmonary medicine, 717-34. https://doi.org/10.4137/CCRPM.S7211
Ejiofor, Stan, and Turner, Alice M. "Pharmacotherapies for COPD." Clinical medicine insights. Circulatory, respiratory and pulmonary medicine vol. 7 (2013): 17-34. doi: https://doi.org/10.4137/CCRPM.S7211
Ejiofor S, Turner AM. Pharmacotherapies for COPD. Clin Med Insights Circ Respir Pulm Med. 2013 Apr 25;7:17-34. doi: 10.4137/CCRPM.S7211. Print 2013. PMID: 23700381; PMCID: PMC3653890.
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Maintenance of the therapeutic effect of two high-dosage antimuscarinics in the management of overactive bladder in elderly women.

International neurourology journal

Kosilov K, Loparev S, Ivanovskaya M, Kosilova L.
PMID: 24466467
Int Neurourol J. 2013 Dec;17(4):191-6. doi: 10.5213/inj.2013.17.4.191. Epub 2013 Dec 31.

PURPOSE: To improve the long-term efficiency of the pharmacologic management of overactive bladder (OAB) in elderly women.METHODS: The study comprised 229 women (mean age, 66.3 years; range, 65-77 years) with urodynamically and clinically confirmed OAB. All patients received the...

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Kosilov K, Loparev S, Ivanovskaya M, et al. Maintenance of the therapeutic effect of two high-dosage antimuscarinics in the management of overactive bladder in elderly women. Int Neurourol J. 2013;17(4):191-6doi: 10.5213/inj.2013.17.4.191.
Kosilov, K., Loparev, S., Ivanovskaya, M., & Kosilova, L. (2013). Maintenance of the therapeutic effect of two high-dosage antimuscarinics in the management of overactive bladder in elderly women. International neurourology journal, 17(4), 191-6. https://doi.org/10.5213/inj.2013.17.4.191
Kosilov, Kirill, et al. "Maintenance of the therapeutic effect of two high-dosage antimuscarinics in the management of overactive bladder in elderly women." International neurourology journal vol. 17,4 (2013): 191-6. doi: https://doi.org/10.5213/inj.2013.17.4.191
Kosilov K, Loparev S, Ivanovskaya M, Kosilova L. Maintenance of the therapeutic effect of two high-dosage antimuscarinics in the management of overactive bladder in elderly women. Int Neurourol J. 2013 Dec;17(4):191-6. doi: 10.5213/inj.2013.17.4.191. Epub 2013 Dec 31. PMID: 24466467; PMCID: PMC3895512.
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Bladder Wall Thickness is Associated with Responsiveness of Storage Symptoms to Alpha-Blockers in Men with Lower Urinary Tract Symptoms.

Korean journal of urology

Park JS, Lee HW, Lee SW, Moon HS, Park HY, Kim YT.
PMID: 22866221
Korean J Urol. 2012 Jul;53(7):487-91. doi: 10.4111/kju.2012.53.7.487. Epub 2012 Jul 19.

PURPOSE: Bladder wall thickness (BWT) is reported to be related to detrusor overactivity and bladder outlet obstruction. We investigated the relationship between BWT and the responsiveness of storage symptoms to alpha-blockers in men with lower urinary tract symptoms (LUTS).MATERIALS...

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Park JS, Lee HW, Lee SW, et al. Bladder Wall Thickness is Associated with Responsiveness of Storage Symptoms to Alpha-Blockers in Men with Lower Urinary Tract Symptoms. Korean J Urol. 2012;53(7):487-91doi: 10.4111/kju.2012.53.7.487.
Park, J. S., Lee, H. W., Lee, S. W., Moon, H. S., Park, H. Y., & Kim, Y. T. (2012). Bladder Wall Thickness is Associated with Responsiveness of Storage Symptoms to Alpha-Blockers in Men with Lower Urinary Tract Symptoms. Korean journal of urology, 53(7), 487-91. https://doi.org/10.4111/kju.2012.53.7.487
Park, Jung Soo, et al. "Bladder Wall Thickness is Associated with Responsiveness of Storage Symptoms to Alpha-Blockers in Men with Lower Urinary Tract Symptoms." Korean journal of urology vol. 53,7 (2012): 487-91. doi: https://doi.org/10.4111/kju.2012.53.7.487
Park JS, Lee HW, Lee SW, Moon HS, Park HY, Kim YT. Bladder Wall Thickness is Associated with Responsiveness of Storage Symptoms to Alpha-Blockers in Men with Lower Urinary Tract Symptoms. Korean J Urol. 2012 Jul;53(7):487-91. doi: 10.4111/kju.2012.53.7.487. Epub 2012 Jul 19. PMID: 22866221; PMCID: PMC3406196.
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Barriers to achieving asthma control in adults: evidence for the role of tiotropium in current management strategies.

Therapeutics and clinical risk management

Jenkins C.
PMID: 30936705
Ther Clin Risk Manag. 2019 Mar 14;15:423-435. doi: 10.2147/TCRM.S177603. eCollection 2019.

Despite the availability of a range of treatment options and management guidelines, a high proportion of adults with asthma remain uncontrolled. The challenge of managing uncontrolled asthma includes providing efficacious treatment while limiting side effects, recognizing situations when a...

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Jenkins C. Barriers to achieving asthma control in adults: evidence for the role of tiotropium in current management strategies. Ther Clin Risk Manag. 2019;15:423-435doi: 10.2147/TCRM.S177603.
Jenkins, C. (2019). Barriers to achieving asthma control in adults: evidence for the role of tiotropium in current management strategies. Therapeutics and clinical risk management, 15423-435. https://doi.org/10.2147/TCRM.S177603
Jenkins, Christine. "Barriers to achieving asthma control in adults: evidence for the role of tiotropium in current management strategies." Therapeutics and clinical risk management vol. 15 (2019): 423-435. doi: https://doi.org/10.2147/TCRM.S177603
Jenkins C. Barriers to achieving asthma control in adults: evidence for the role of tiotropium in current management strategies. Ther Clin Risk Manag. 2019 Mar 14;15:423-435. doi: 10.2147/TCRM.S177603. eCollection 2019. PMID: 30936705; PMCID: PMC6422417.
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Patient-reported outcomes and considerations in the management of COPD: focus on indacaterol/glycopyrronium bromide.

Patient preference and adherence

Ridolo E, Pellicelli I, Gritti B, Incorvaia C.
PMID: 30679906
Patient Prefer Adherence. 2019 Jan 14;13:145-150. doi: 10.2147/PPA.S166704. eCollection 2019.

Dual bronchodilation with long-acting beta-2 agonists and muscarinic antagonists is recommended in patients with severe to very severe COPD. Among dual bronchodilator combinations, indacaterol/glycopyrronium combination (IGC) received evidence of higher efficacy and good safety compared with monotherapy with either...

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Ridolo E, Pellicelli I, Gritti B, et al. Patient-reported outcomes and considerations in the management of COPD: focus on indacaterol/glycopyrronium bromide. Patient Prefer Adherence. 2019;13:145-150doi: 10.2147/PPA.S166704.
Ridolo, E., Pellicelli, I., Gritti, B., & Incorvaia, C. (2019). Patient-reported outcomes and considerations in the management of COPD: focus on indacaterol/glycopyrronium bromide. Patient preference and adherence, 13145-150. https://doi.org/10.2147/PPA.S166704
Ridolo, Erminia, et al. "Patient-reported outcomes and considerations in the management of COPD: focus on indacaterol/glycopyrronium bromide." Patient preference and adherence vol. 13 (2019): 145-150. doi: https://doi.org/10.2147/PPA.S166704
Ridolo E, Pellicelli I, Gritti B, Incorvaia C. Patient-reported outcomes and considerations in the management of COPD: focus on indacaterol/glycopyrronium bromide. Patient Prefer Adherence. 2019 Jan 14;13:145-150. doi: 10.2147/PPA.S166704. eCollection 2019. PMID: 30679906; PMCID: PMC6338236.
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Showing 1 to 12 of 86 entries