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Showing 1 to 12 of 297 entries
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Regional Colonic Transit Pattern Does Not Conclusively Identify Evacuation Disorders in Constipated Patients with Delayed Colonic Transit.

Journal of neurogastroenterology and motility

Park SY, Burton D, Busciglio I, Eckert D, Camilleri M.
PMID: 27667753
J Neurogastroenterol Motil. 2017 Jan 30;23(1):92-100. doi: 10.5056/jnm16066.

BACKGROUND/AIMS: After exclusion of structural diseases, chronic constipation may be associated with normal or slow transit or rectal evacuation disorders. We evaluated: (1) clinical features and anorectal function, (2) difference of regional colonic transit according to the presence or...

The Analgesic Efficacy of Intrathecal Bupivacaine and Fentanyl with Added Neostigmine or Magnesium Sulphate.

Anesthesiology and pain medicine

Mokaram Dori M, Foruzin F.
PMID: 28975069
Anesth Pain Med. 2016 Sep 18;6(6):e9651. doi: 10.5812/aapm.9651. eCollection 2016 Dec.

BACKGROUND: An appropriate anesthesia duration with minimal side effects and prolonged postoperative analgesia are the ideal characteristics of an intrathecal drug used during spinal anesthesia. Neostigmine and magnesium sulphate have been used as spinal anesthetic additives with narcotics and...

Management of Residual Neuromuscular Blockade Recovery: Age-Old Problem with a New Solution.

Case reports in anesthesiology

Green MS, Venkatesh AG, Venkataramani R.
PMID: 28392946
Case Rep Anesthesiol. 2017;2017:8197035. doi: 10.1155/2017/8197035. Epub 2017 Mar 14.

Neostigmine has been traditionally used as the agent of choice to reverse Neuromuscular Blockade (NMB) after muscle paralysis during general anesthesia. However, the use of neostigmine has not been without untoward events. Sugammadex is a novel drug that selectively...

Relationship between first-twitch depression and train-of-four ratio during sugammadex reversal of rocuronium-induced neuromuscular blockade.

Korean journal of anesthesiology

Kim KS, Oh YN, Kim TY, Oh SY, Sin YH.
PMID: 27274368
Korean J Anesthesiol. 2016 Jun;69(3):239-43. doi: 10.4097/kjae.2016.69.3.239. Epub 2016 Jun 01.

BACKGROUND: The primary outcome of sugammadex reversal for rocuronium-induced neuromuscular block (NMB) is a train-of-four ratio (TOFR) of 0.9, not first twitch (T1) height. We investigated whether the recovery of TOFR or T1 differs based on the reversal of...

The combination of sugammadex and neostigmine can reduce the dosage of sugammadex during recovery from the moderate neuromuscular blockade.

Korean journal of anesthesiology

Cheong SH, Ki S, Lee J, Lee JH, Kim MH, Hur D, Cho K, Lim SH, Lee KM, Kim YJ, Lee W.
PMID: 26634077
Korean J Anesthesiol. 2015 Dec;68(6):547-55. doi: 10.4097/kjae.2015.68.6.547. Epub 2015 Nov 25.

BACKGROUND: Sugammadex is a novel neuromuscular reversal agent, but its associated hypersensitivity reaction and high cost have been obstacles to its widespread use. In the interest of reducing the necessary dosage of sugammadex, the reversal time of the combined...

Postoperative Residual Neuromuscular Paralysis at an Australian Tertiary Children's Hospital.

Anesthesiology research and practice

Ledowski T, O'Dea B, Meyerkort L, Hegarty M, von Ungern-Sternberg BS.
PMID: 26064105
Anesthesiol Res Pract. 2015;2015:410248. doi: 10.1155/2015/410248. Epub 2015 May 10.

Purpose. Residual neuromuscular blockade (RNMB) is known to be a significant but frequently overlooked complication after the use of neuromuscular blocking agents (NMBA). Aim of this prospective audit was to investigate the incidence and severity of RNMB at our...

[Effect of ropivacaine combined with pancuronium on neuromuscular transmission and effectiveness of neostigmine and 4-aminopyridine for blockade reversal: experimental study].

Revista brasileira de anestesiologia

Braga Ade F, Carvalho VH, Braga FS, Potério GM, Santos FN.
PMID: 25666937
Rev Bras Anestesiol. 2015 Mar-Apr;65(2):136-40. doi: 10.1016/j.bjan.2013.10.020. Epub 2014 Nov 08.

BACKGROUND AND OBJECTIVES: The local anesthetic effects on neuromuscular junction and its influence on blockade produced by nondepolarizing neuromuscular blockers are still under-investigated; however, this interaction has been described in experimental studies and in humans. The aim of this...

A Double-Blind Randomized Clinical Trial Comparing the Effect of Neostigmine and Metoclopramide on Gastric Residual Volume of Mechanically Ventilated ICU Patients.

Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH

Gholipour Baradari A, Alipour A, Firouzian A, Moarab L, Emami Zeydi A.
PMID: 28077899
Acta Inform Med. 2016 Dec;24(6):385-389. doi: 10.5455/aim.2016.24.385-389.

BACKGROUND: In critically ill patients, enteral feeding through the nasogastric tube is the method of choice for nutritional support. Gastrointestinal feeding intolerance and disturbed gastric emptying are common challenges in these patients. The aim of this study was to...

A comparison between intrathecal clonidine and neostigmine as an adjuvant to bupivacaine in the subarachnoid block for elective abdominal hysterectomy operations: A prospective, double-blind and randomized controlled study.

Saudi journal of anaesthesia

Bhar D, RoyBasunia S, Das A, Kundu SB, Mondal RC, Halder PS, Mandal SK, Chattopadhyay S.
PMID: 27051359
Saudi J Anaesth. 2016 Apr-Jun;10(2):121-6. doi: 10.4103/1658-354X.168797.

BACKGROUND AND AIMS: Adjuvant to the local anesthetic agent has proven benefits when used intrathecally. With regards to intrathecal bupivacaine as control, we have compared in this study the effects of clonidine and neostigmine when co-administered intrathecally with hyperbaric...

A case with improvement of blepharospasm by zolpidem.

Journal of movement disorders

Sunwoo M, Cho J, Lee JH, Kim GS, Kim JH, Choi SA.
PMID: 24868394
J Mov Disord. 2011 May;4(1):53-4. doi: 10.14802/jmd.11010. Epub 2011 Apr 30.

Zolpidem is usually used for the treatment of insomnia as a hypnotic drug. It was also suggested to be effective in the treatment of dystonia in some studies. A 74-year-old woman had been suffering from frequent and intense bilateral...

Some Pharmacodynamic Aspects of Cefepime.

Journal of pharmaceutics

Elsayed MG, Elkomy AA, Elbadawy M.
PMID: 26555975
J Pharm (Cairo). 2013;2013:381910. doi: 10.1155/2013/381910. Epub 2012 Nov 07.

Some pharmacodynamic effects of cefepime, a new injectable semisynthetic cephalosporin, were studied in laboratory animals and the following results were obtained. Cefepime maximally stimulated isolated guinea pig's ileum, rat's colon (80 μg/mL bath), and rabbit's duodenum (400 μg/mL bath)....

Postponed effect of neostigmine on oxidative homeostasis.

Interdisciplinary toxicology

Pohanka M.
PMID: 26109890
Interdiscip Toxicol. 2014 Sep;7(3):134-8. doi: 10.2478/intox-2014-0018. Epub 2014 Dec 30.

Cholinesterases are enzymes able to hydrolyze the neurotransmitter acetylcholine and thus to terminate transmission. Once the enzymes are inhibited, excitotoxicity can appear in the adjacent cells. It is well known that oxidative stress is involved in the toxicity of...

Showing 1 to 12 of 297 entries