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Showing 1 to 12 of 99 entries
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Kinetics of cytochrome P450 enzymes for metabolism of sodium tanshinone IIA sulfonate in vitro.

Chinese medicine

Ouyang DS, Huang WH, Chen D, Zhang W, Tan ZR, Peng JB, Wang YC, Guo Y, Hu DL, Xiao J, Chen Y.
PMID: 27006687
Chin Med. 2016 Mar 22;11:11. doi: 10.1186/s13020-016-0083-z. eCollection 2016.

BACKGROUND: Sodium tanshinone IIA sulfonate (STS) is a water-soluble derivative of tanshinone IIA for treating cardiovascular disorders. The roles of cytochrome P450 enzymes (CYPs) in the metabolism of STS have remained unclear. This study aims to screen the main...

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Ouyang DS, Huang WH, Chen D, et al. Kinetics of cytochrome P450 enzymes for metabolism of sodium tanshinone IIA sulfonate in vitro. Chin Med. 2016;11:11doi: 10.1186/s13020-016-0083-z.
Ouyang, D. S., Huang, W. H., Chen, D., Zhang, W., Tan, Z. R., Peng, J. B., Wang, Y. C., Guo, Y., Hu, D. L., Xiao, J., & Chen, Y. (2016). Kinetics of cytochrome P450 enzymes for metabolism of sodium tanshinone IIA sulfonate in vitro. Chinese medicine, 1111. https://doi.org/10.1186/s13020-016-0083-z
Ouyang, Dong-Sheng, et al. "Kinetics of cytochrome P450 enzymes for metabolism of sodium tanshinone IIA sulfonate in vitro." Chinese medicine vol. 11 (2016): 11. doi: https://doi.org/10.1186/s13020-016-0083-z
Ouyang DS, Huang WH, Chen D, Zhang W, Tan ZR, Peng JB, Wang YC, Guo Y, Hu DL, Xiao J, Chen Y. Kinetics of cytochrome P450 enzymes for metabolism of sodium tanshinone IIA sulfonate in vitro. Chin Med. 2016 Mar 22;11:11. doi: 10.1186/s13020-016-0083-z. eCollection 2016. PMID: 27006687; PMCID: PMC4802617.
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Effect of Radix Sophorae Tonkinensis on the activity of cytochrome P450 isoforms in rats.

International journal of clinical and experimental medicine

Cai J, Ma J, Xu K, Gao G, Xiang Y, Lin C.
PMID: 26309650
Int J Clin Exp Med. 2015 Jun 15;8(6):9737-43. eCollection 2015.

Radix Sophorae Tonkinensis (S. tonkinensis) is the processed lateral root of Sophora subprostrata (Leguminosae) that widely distributed over the southwest China. Radix Sophorae Tonkinensis has been widely used as a Chinese medicinal herb for the treatment of disease such...

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Cai J, Ma J, Xu K, et al. Effect of Radix Sophorae Tonkinensis on the activity of cytochrome P450 isoforms in rats. Int J Clin Exp Med. 2015;8(6):9737-43
Cai, J., Ma, J., Xu, K., Gao, G., Xiang, Y., & Lin, C. (2015). Effect of Radix Sophorae Tonkinensis on the activity of cytochrome P450 isoforms in rats. International journal of clinical and experimental medicine, 8(6), 9737-43.
Cai, Jinzhang, et al. "Effect of Radix Sophorae Tonkinensis on the activity of cytochrome P450 isoforms in rats." International journal of clinical and experimental medicine vol. 8,6 (2015): 9737-43.
Cai J, Ma J, Xu K, Gao G, Xiang Y, Lin C. Effect of Radix Sophorae Tonkinensis on the activity of cytochrome P450 isoforms in rats. Int J Clin Exp Med. 2015 Jun 15;8(6):9737-43. eCollection 2015. PMID: 26309650; PMCID: PMC4538074.
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In vitro inhibitory effects of plumbagin, the promising antimalarial candidate, on human cytochrome P450 enzymes.

Asian Pacific journal of tropical medicine

Sumsakul W, Chaijaroenkul W, Na-Bangchang K.
PMID: 26614990
Asian Pac J Trop Med. 2015 Nov;8(11):914-918. doi: 10.1016/j.apjtm.2015.10.016. Epub 2015 Oct 09.

OBJECTIVE: To investigate the propensity of plumbagin to inhibit the three isoforms of human cytochrome P450 (CYP), i.e., CYP1A2, CYP2C19, and CYP3A4 using human liver microsomes in vitro.METHODS: Inhibitory effects of plumbagin on the three human CYP isoforms were...

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Sumsakul W, Chaijaroenkul W, Na-Bangchang K. In vitro inhibitory effects of plumbagin, the promising antimalarial candidate, on human cytochrome P450 enzymes. Asian Pac J Trop Med. 2015;8(11):914-918doi: 10.1016/j.apjtm.2015.10.016.
Sumsakul, W., Chaijaroenkul, W., & Na-Bangchang, K. (2015). In vitro inhibitory effects of plumbagin, the promising antimalarial candidate, on human cytochrome P450 enzymes. Asian Pacific journal of tropical medicine, 8(11), 914-918. https://doi.org/10.1016/j.apjtm.2015.10.016
Sumsakul, Wiriyaporn, et al. "In vitro inhibitory effects of plumbagin, the promising antimalarial candidate, on human cytochrome P450 enzymes." Asian Pacific journal of tropical medicine vol. 8,11 (2015): 914-918. doi: https://doi.org/10.1016/j.apjtm.2015.10.016
Sumsakul W, Chaijaroenkul W, Na-Bangchang K. In vitro inhibitory effects of plumbagin, the promising antimalarial candidate, on human cytochrome P450 enzymes. Asian Pac J Trop Med. 2015 Nov;8(11):914-918. doi: 10.1016/j.apjtm.2015.10.016. Epub 2015 Oct 09. PMID: 26614990.
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Evaluation of the impact of Flos Daturae on rat hepatic cytochrome P450 enzymes by cocktail probe drugs.

International journal of clinical and experimental medicine

Geng P, Wang S, Wang C, Chen J, Zhang L, Yang S, Wen C, Zhou Y, Zhang M.
PMID: 26885208
Int J Clin Exp Med. 2015 Dec 15;8(12):22310-8. eCollection 2015.

Flos Daturae, known as "baimantuoluo" or "yangjinhua" in China, has been used for centuries in Traditional Chinese Medicine for the treatment of asthma, convulsions, pain, and rheumatism. To investigate the influences of Flos Daturae on the activities of rat...

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Geng P, Wang S, Wang C, et al. Evaluation of the impact of Flos Daturae on rat hepatic cytochrome P450 enzymes by cocktail probe drugs. Int J Clin Exp Med. 2015;8(12):22310-8
Geng, P., Wang, S., Wang, C., Chen, J., Zhang, L., Yang, S., Wen, C., Zhou, Y., & Zhang, M. (2015). Evaluation of the impact of Flos Daturae on rat hepatic cytochrome P450 enzymes by cocktail probe drugs. International journal of clinical and experimental medicine, 8(12), 22310-8.
Geng, Peiwu, et al. "Evaluation of the impact of Flos Daturae on rat hepatic cytochrome P450 enzymes by cocktail probe drugs." International journal of clinical and experimental medicine vol. 8,12 (2015): 22310-8.
Geng P, Wang S, Wang C, Chen J, Zhang L, Yang S, Wen C, Zhou Y, Zhang M. Evaluation of the impact of Flos Daturae on rat hepatic cytochrome P450 enzymes by cocktail probe drugs. Int J Clin Exp Med. 2015 Dec 15;8(12):22310-8. eCollection 2015. PMID: 26885208; PMCID: PMC4729994.
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Analysis of tablets containing acetylsalicylic acid and phenylephrine by high-performance liquid chromatography.

Journal of pharmaceutical and biomedical analysis

Wouters I, Roets E, Hoogmartens J.
PMID: 16867728
J Pharm Biomed Anal. 1984;2(3):481-90. doi: 10.1016/0731-7085(84)80051-5.

A high-performance liquid chromatographic method permitted the quantitation of acetylsalicylic acid, phenylephrine, caffeine and phenacetin in tablets, and of the main impurities, salicylic acid and mono- and diacetyl derivatives of phenylephrine. A C8 reversed-phase column was used with a...

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Wouters I, Roets E, Hoogmartens J. Analysis of tablets containing acetylsalicylic acid and phenylephrine by high-performance liquid chromatography. J Pharm Biomed Anal. 1984;2(3):481-90doi: 10.1016/0731-7085(84)80051-5.
Wouters, I., Roets, E., & Hoogmartens, J. (1984). Analysis of tablets containing acetylsalicylic acid and phenylephrine by high-performance liquid chromatography. Journal of pharmaceutical and biomedical analysis, 2(3), 481-90. https://doi.org/10.1016/0731-7085(84)80051-5
Wouters, I, et al. "Analysis of tablets containing acetylsalicylic acid and phenylephrine by high-performance liquid chromatography." Journal of pharmaceutical and biomedical analysis vol. 2,3 (1984): 481-90. doi: https://doi.org/10.1016/0731-7085(84)80051-5
Wouters I, Roets E, Hoogmartens J. Analysis of tablets containing acetylsalicylic acid and phenylephrine by high-performance liquid chromatography. J Pharm Biomed Anal. 1984;2(3):481-90. doi: 10.1016/0731-7085(84)80051-5. PMID: 16867728.
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Chronic Pyelonephritis, Chronic Interstitial Nephritis and Phenacetin Toxicity.

Canadian Medical Association journal

[No authors listed]
PMID: 20327014
Can Med Assoc J. 1962 Jan 27;86(4):189-90.

No abstract available.

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Chronic Pyelonephritis, Chronic Interstitial Nephritis and Phenacetin Toxicity. Can Med Assoc J. 1962;86(4):189-90
(1962). Chronic Pyelonephritis, Chronic Interstitial Nephritis and Phenacetin Toxicity. Canadian Medical Association journal, 86(4), 189-90.
"Chronic Pyelonephritis, Chronic Interstitial Nephritis and Phenacetin Toxicity." Canadian Medical Association journal vol. 86,4 (1962): 189-90.
Chronic Pyelonephritis, Chronic Interstitial Nephritis and Phenacetin Toxicity. Can Med Assoc J. 1962 Jan 27;86(4):189-90. PMID: 20327014; PMCID: PMC1848704.
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Nephrotoxic lesions from 5-aminosalicylic Acid.

British medical journal

Calder IC, Funder CC, Green CR, Ham KN, Tange JD.
PMID: 20791817
Br Med J. 1972 Jan 15;1(5793):152-4. doi: 10.1136/bmj.1.5793.152.

5-Aminosalicylic acid given to rats as a single intravenous injection led to necrosis of the proximal convoluted tubules and of the renal papilla. These two lesions developed at the same time and the cortical lesions did not appear to...

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Calder IC, Funder CC, Green CR, et al. Nephrotoxic lesions from 5-aminosalicylic Acid. Br Med J. 1972;1(5793):152-4doi: 10.1136/bmj.1.5793.152.
Calder, I. C., Funder, C. C., Green, C. R., Ham, K. N., & Tange, J. D. (1972). Nephrotoxic lesions from 5-aminosalicylic Acid. British medical journal, 1(5793), 152-4. https://doi.org/10.1136/bmj.1.5793.152
Calder, I C, et al. "Nephrotoxic lesions from 5-aminosalicylic Acid." British medical journal vol. 1,5793 (1972): 152-4. doi: https://doi.org/10.1136/bmj.1.5793.152
Calder IC, Funder CC, Green CR, Ham KN, Tange JD. Nephrotoxic lesions from 5-aminosalicylic Acid. Br Med J. 1972 Jan 15;1(5793):152-4. doi: 10.1136/bmj.1.5793.152. PMID: 20791817; PMCID: PMC1787127.
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Evaluation of the effect of apatinib (YN968D1) on cytochrome P450 enzymes with cocktail probe drugs in rats by UPLC-MS/MS.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Zhou Y, Wang S, Ding T, Chen M, Wang L, Wu M, Hu G, Lu X.
PMID: 25464097
J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Dec 15;973:68-75. doi: 10.1016/j.jchromb.2014.10.013. Epub 2014 Oct 22.

An accurate and validated liquid chromatography method and a triple quadrupole mass spectrometry method were developed and validated to simultaneously evaluate the cytochrome P450 (CYP) enzymes in vivo using the co-administration of these probes. Phenacetin, losartan, metoprolol and midazolam...

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Zhou Y, Wang S, Ding T, et al. Evaluation of the effect of apatinib (YN968D1) on cytochrome P450 enzymes with cocktail probe drugs in rats by UPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2014;973:68-75doi: 10.1016/j.jchromb.2014.10.013.
Zhou, Y., Wang, S., Ding, T., Chen, M., Wang, L., Wu, M., Hu, G., & Lu, X. (2014). Evaluation of the effect of apatinib (YN968D1) on cytochrome P450 enzymes with cocktail probe drugs in rats by UPLC-MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 97368-75. https://doi.org/10.1016/j.jchromb.2014.10.013
Zhou, Yunfang, et al. "Evaluation of the effect of apatinib (YN968D1) on cytochrome P450 enzymes with cocktail probe drugs in rats by UPLC-MS/MS." Journal of chromatography. B, Analytical technologies in the biomedical and life sciences vol. 973 (2014): 68-75. doi: https://doi.org/10.1016/j.jchromb.2014.10.013
Zhou Y, Wang S, Ding T, Chen M, Wang L, Wu M, Hu G, Lu X. Evaluation of the effect of apatinib (YN968D1) on cytochrome P450 enzymes with cocktail probe drugs in rats by UPLC-MS/MS. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Dec 15;973:68-75. doi: 10.1016/j.jchromb.2014.10.013. Epub 2014 Oct 22. PMID: 25464097.
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Development and validation of liquid chromatography-mass spectrometry method for the estimation of rifampicin in plasma.

Indian journal of pharmaceutical sciences

Patil JS, Suresh S, Sureshbabu AR, Rajesh MS.
PMID: 22923869
Indian J Pharm Sci. 2011 Sep;73(5):558-63. doi: 10.4103/0250-474X.99014.

A selective, rapid and sensitive liquid chromatography-mass spectrometry method was developed for the quantitative estimation of rifampicin in plasma. With phenacetin as internal standard, sample pretreatment involved a one-step extraction with ethyl acetate from plasma. The sample was analyzed...

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Patil JS, Suresh S, Sureshbabu AR, et al. Development and validation of liquid chromatography-mass spectrometry method for the estimation of rifampicin in plasma. Indian J Pharm Sci. 2011;73(5):558-63doi: 10.4103/0250-474X.99014.
Patil, J. S., Suresh, S., Sureshbabu, A. R., & Rajesh, M. S. (2011). Development and validation of liquid chromatography-mass spectrometry method for the estimation of rifampicin in plasma. Indian journal of pharmaceutical sciences, 73(5), 558-63. https://doi.org/10.4103/0250-474X.99014
Patil, J S, et al. "Development and validation of liquid chromatography-mass spectrometry method for the estimation of rifampicin in plasma." Indian journal of pharmaceutical sciences vol. 73,5 (2011): 558-63. doi: https://doi.org/10.4103/0250-474X.99014
Patil JS, Suresh S, Sureshbabu AR, Rajesh MS. Development and validation of liquid chromatography-mass spectrometry method for the estimation of rifampicin in plasma. Indian J Pharm Sci. 2011 Sep;73(5):558-63. doi: 10.4103/0250-474X.99014. PMID: 22923869; PMCID: PMC3425068.
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The Importance and Place of Methemoglobin and Carboxyhemoglobin Levels in the Diagnosis and Prognosis of Pulmonary Embolism.

Tanaffos

Uzer F, Ozbudak O.
PMID: 31423137
Tanaffos. 2019 Jan;18(1):25-33.

BACKGROUND: This is a retrospective study to investigate the effects of Carboxyhemoglobin (COHb) and Methemoglobin (MetHb) levels in the diagnosis and prognosis of Pulmonary Thromboembolism (PTE).MATERIALS AND METHODS: Cases that were confirmed with PTE diagnosis using CT Pulmonary Angiography...

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Uzer F, Ozbudak O. The Importance and Place of Methemoglobin and Carboxyhemoglobin Levels in the Diagnosis and Prognosis of Pulmonary Embolism. Tanaffos. 2019;18(1):25-33
Uzer, F., & Ozbudak, O. (2019). The Importance and Place of Methemoglobin and Carboxyhemoglobin Levels in the Diagnosis and Prognosis of Pulmonary Embolism. Tanaffos, 18(1), 25-33.
Uzer, Fatih, and Ozbudak, Omer. "The Importance and Place of Methemoglobin and Carboxyhemoglobin Levels in the Diagnosis and Prognosis of Pulmonary Embolism." Tanaffos vol. 18,1 (2019): 25-33.
Uzer F, Ozbudak O. The Importance and Place of Methemoglobin and Carboxyhemoglobin Levels in the Diagnosis and Prognosis of Pulmonary Embolism. Tanaffos. 2019 Jan;18(1):25-33. PMID: 31423137; PMCID: PMC6690330.
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An in-vitro cocktail assay for assessing compound-mediated inhibition of six major cytochrome P450 enzymes.

Journal of pharmaceutical analysis

Wang JJ, Guo JJ, Zhan J, Bu HZ, Lin JH.
PMID: 29403890
J Pharm Anal. 2014 Aug;4(4):270-278. doi: 10.1016/j.jpha.2014.01.001. Epub 2014 Feb 14.

An efficient screening assay was developed and validated for simultaneous assessment of compound-mediated inhibition of six major human cytochrome P450 (CYP) enzymes. This method employed a cocktail of six probe substrates (i.e., phenacetin, amodiaquine, diclofenac, S-mephenytoin, dextromethorphan and midazolam...

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Wang JJ, Guo JJ, Zhan J, et al. An in-vitro cocktail assay for assessing compound-mediated inhibition of six major cytochrome P450 enzymes. J Pharm Anal. 2014;4(4):270-278doi: 10.1016/j.jpha.2014.01.001.
Wang, J. J., Guo, J. J., Zhan, J., Bu, H. Z., & Lin, J. H. (2014). An in-vitro cocktail assay for assessing compound-mediated inhibition of six major cytochrome P450 enzymes. Journal of pharmaceutical analysis, 4(4), 270-278. https://doi.org/10.1016/j.jpha.2014.01.001
Wang, Jing-Jing, et al. "An in-vitro cocktail assay for assessing compound-mediated inhibition of six major cytochrome P450 enzymes." Journal of pharmaceutical analysis vol. 4,4 (2014): 270-278. doi: https://doi.org/10.1016/j.jpha.2014.01.001
Wang JJ, Guo JJ, Zhan J, Bu HZ, Lin JH. An in-vitro cocktail assay for assessing compound-mediated inhibition of six major cytochrome P450 enzymes. J Pharm Anal. 2014 Aug;4(4):270-278. doi: 10.1016/j.jpha.2014.01.001. Epub 2014 Feb 14. PMID: 29403890; PMCID: PMC5761213.
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Phenacetine as an Antipyretic.

Glasgow medical journal

Carslaw JH.
PMID: 30434999
Glasgow Med J. 1888 Jul;30(1):64-67.

No abstract available.

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Carslaw JH. Phenacetine as an Antipyretic. Glasgow Med J. 1888;30(1):64-67
Carslaw, J. H. (1888). Phenacetine as an Antipyretic. Glasgow medical journal, 30(1), 64-67.
Carslaw, John H. "Phenacetine as an Antipyretic." Glasgow medical journal vol. 30,1 (1888): 64-67.
Carslaw JH. Phenacetine as an Antipyretic. Glasgow Med J. 1888 Jul;30(1):64-67. PMID: 30434999; PMCID: PMC5924302.
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Showing 1 to 12 of 99 entries