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One-Pot Synthesis of Pyrrolo[3,2,1-kl]phenothiazines through Copper-Catalyzed Tandem Coupling/Double Cyclization Reaction.

The Journal of organic chemistry

Tang J, Xu B, Mao X, Yang H, Wang X, Lv X.
PMID: 26430717
J Org Chem. 2015 Nov 06;80(21):11108-14. doi: 10.1021/acs.joc.5b01745. Epub 2015 Oct 09.

A novel and efficient synthesis of pyrrolo[3,2,1-kl]phenothiazines has been developed through a Cu(I)-catalyzed tandem C-S coupling/double cyclization process. Using 2-alkynyl-6-iodoanilines and o-bromobenzenethiols as the starting materials, a wide range of pyrrolo[3,2,1-kl]phenothiazine derivatives were facilely and efficiently generated in one...

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Tang J, Xu B, Mao X, et al. One-Pot Synthesis of Pyrrolo[3,2,1-kl]phenothiazines through Copper-Catalyzed Tandem Coupling/Double Cyclization Reaction. J Org Chem. 2015;80(21):11108-14doi: 10.1021/acs.joc.5b01745.
Tang, J., Xu, B., Mao, X., Yang, H., Wang, X., & Lv, X. (2015). One-Pot Synthesis of Pyrrolo[3,2,1-kl]phenothiazines through Copper-Catalyzed Tandem Coupling/Double Cyclization Reaction. The Journal of organic chemistry, 80(21), 11108-14. https://doi.org/10.1021/acs.joc.5b01745
Tang, Jiaming, et al. "One-Pot Synthesis of Pyrrolo[3,2,1-kl]phenothiazines through Copper-Catalyzed Tandem Coupling/Double Cyclization Reaction." The Journal of organic chemistry vol. 80,21 (2015): 11108-14. doi: https://doi.org/10.1021/acs.joc.5b01745
Tang J, Xu B, Mao X, Yang H, Wang X, Lv X. One-Pot Synthesis of Pyrrolo[3,2,1-kl]phenothiazines through Copper-Catalyzed Tandem Coupling/Double Cyclization Reaction. J Org Chem. 2015 Nov 06;80(21):11108-14. doi: 10.1021/acs.joc.5b01745. Epub 2015 Oct 09. PMID: 26430717.
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Phenothiazine vs 5HT3 antagonist prophylactic regimens to prevent Post-Anesthesia Care Unit rescue antiemetic: an observational study.

Open Journal of Anesthesiology

Ruiz JR, Ensor JE, Lim JW, Van Meter A, Rahlfs TF.
PMID: 26635998
Open J Anesthesiol. 2015 Feb;5(2):27-32. doi: 10.4236/ojanes.2015.52006.

PURPOSE: Our practitioners are asked to consider a patient's postoperative nausea and vomiting (PONV) risk profile when developing their prophylactic antiemetic strategy. There is wide variation in employed strategies, and we have yet to determine the most effective PONV...

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Ruiz JR, Ensor JE, Lim JW, et al. Phenothiazine vs 5HT3 antagonist prophylactic regimens to prevent Post-Anesthesia Care Unit rescue antiemetic: an observational study. Open J Anesthesiol. 2015;5(2):27-32doi: 10.4236/ojanes.2015.52006.
Ruiz, J. R., Ensor, J. E., Lim, J. W., Van Meter, A., & Rahlfs, T. F. (2015). Phenothiazine vs 5HT3 antagonist prophylactic regimens to prevent Post-Anesthesia Care Unit rescue antiemetic: an observational study. Open Journal of Anesthesiology, 5(2), 27-32. https://doi.org/10.4236/ojanes.2015.52006
Ruiz, Joseph R, et al. "Phenothiazine vs 5HT3 antagonist prophylactic regimens to prevent Post-Anesthesia Care Unit rescue antiemetic: an observational study." Open Journal of Anesthesiology vol. 5,2 (2015): 27-32. doi: https://doi.org/10.4236/ojanes.2015.52006
Ruiz JR, Ensor JE, Lim JW, Van Meter A, Rahlfs TF. Phenothiazine vs 5HT3 antagonist prophylactic regimens to prevent Post-Anesthesia Care Unit rescue antiemetic: an observational study. Open J Anesthesiol. 2015 Feb;5(2):27-32. doi: 10.4236/ojanes.2015.52006. PMID: 26635998; PMCID: PMC4664192.
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Beyond the Hammett Effect: Using Strain to Alter the Landscape of Electrochemical Potentials.

Chemphyschem : a European journal of chemical physics and physical chemistry

Casselman MD, Elliott CF, Modekrutti S, Zhang PL, Parkin SR, Risko C, Odom SA.
PMID: 28590586
Chemphyschem. 2017 Aug 18;18(16):2142-2146. doi: 10.1002/cphc.201700607. Epub 2017 Jun 21.

The substitution of sterically bulky groups at precise locations along the periphery of fused-ring aromatic systems is demonstrated to increase electrochemical oxidation potentials by preventing relaxation events in the oxidized state. Phenothiazines, which undergo significant geometric relaxation upon oxidation,...

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Casselman MD, Elliott CF, Modekrutti S, et al. Beyond the Hammett Effect: Using Strain to Alter the Landscape of Electrochemical Potentials. Chemphyschem. 2017;18(16):2142-2146doi: 10.1002/cphc.201700607.
Casselman, M. D., Elliott, C. F., Modekrutti, S., Zhang, P. L., Parkin, S. R., Risko, C., & Odom, S. A. (2017). Beyond the Hammett Effect: Using Strain to Alter the Landscape of Electrochemical Potentials. Chemphyschem : a European journal of chemical physics and physical chemistry, 18(16), 2142-2146. https://doi.org/10.1002/cphc.201700607
Casselman, Matthew D, et al. "Beyond the Hammett Effect: Using Strain to Alter the Landscape of Electrochemical Potentials." Chemphyschem : a European journal of chemical physics and physical chemistry vol. 18,16 (2017): 2142-2146. doi: https://doi.org/10.1002/cphc.201700607
Casselman MD, Elliott CF, Modekrutti S, Zhang PL, Parkin SR, Risko C, Odom SA. Beyond the Hammett Effect: Using Strain to Alter the Landscape of Electrochemical Potentials. Chemphyschem. 2017 Aug 18;18(16):2142-2146. doi: 10.1002/cphc.201700607. Epub 2017 Jun 21. PMID: 28590586.
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Tapentadol: Can It Kill Two Birds with One Stone without Breaking Windows?.

The Korean journal of pain

Chang EJ, Choi EJ, Kim KH.
PMID: 27413479
Korean J Pain. 2016 Jul;29(3):153-7. doi: 10.3344/kjp.2016.29.3.153. Epub 2016 Jul 01.

Tapentadol is a novel oral analgesic with a dual mode of action as an agonist of the µ-opioid receptor (MOR), and as a norepinephrine reuptake inhibitor (NRI) all in a single molecule. Immediate release (IR) tapentadol shows its analgesic...

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Chang EJ, Choi EJ, Kim KH. Tapentadol: Can It Kill Two Birds with One Stone without Breaking Windows?. Korean J Pain. 2016;29(3):153-7doi: 10.3344/kjp.2016.29.3.153.
Chang, E. J., Choi, E. J., & Kim, K. H. (2016). Tapentadol: Can It Kill Two Birds with One Stone without Breaking Windows?. The Korean journal of pain, 29(3), 153-7. https://doi.org/10.3344/kjp.2016.29.3.153
Chang, Eun Jung, et al. "Tapentadol: Can It Kill Two Birds with One Stone without Breaking Windows?." The Korean journal of pain vol. 29,3 (2016): 153-7. doi: https://doi.org/10.3344/kjp.2016.29.3.153
Chang EJ, Choi EJ, Kim KH. Tapentadol: Can It Kill Two Birds with One Stone without Breaking Windows?. Korean J Pain. 2016 Jul;29(3):153-7. doi: 10.3344/kjp.2016.29.3.153. Epub 2016 Jul 01. PMID: 27413479; PMCID: PMC4942642.
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Nausea and Vomiting.

Current treatment options in gastroenterology

Fraga XF, Malagelada JR.
PMID: 12095471
Curr Treat Options Gastroenterol. 2002 Aug;5(4):241-250. doi: 10.1007/s11938-002-0046-6.

Nausea and vomiting are rather stereotyped symptoms. The challenge is that nausea and vomiting have many different causes and, in some patients, management may be rather complex. The clue is to determine the causal factor early. It helps to...

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Fraga XF, Malagelada JR. Nausea and Vomiting. Curr Treat Options Gastroenterol. 2002;5(4):241-250doi: 10.1007/s11938-002-0046-6.
Fraga, X. F., & Malagelada, J. R. (2002). Nausea and Vomiting. Current treatment options in gastroenterology, 5(4), 241-250. https://doi.org/10.1007/s11938-002-0046-6
Fraga, Xose Fernández, and Malagelada, Juan R.. "Nausea and Vomiting." Current treatment options in gastroenterology vol. 5,4 (2002): 241-250. doi: https://doi.org/10.1007/s11938-002-0046-6
Fraga XF, Malagelada JR. Nausea and Vomiting. Curr Treat Options Gastroenterol. 2002 Aug;5(4):241-250. doi: 10.1007/s11938-002-0046-6. PMID: 12095471.
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N-substituted phenothiazines as redox indicators in bromatometry.

Talanta

Gowda HS, Ahmed SA.
PMID: 18962421
Talanta. 1979 Mar;26(3):233-5. doi: 10.1016/0039-9140(79)80055-7.

Diethazine hydrochloride, butaperazine dimaleate, trifluoperazine hydrochloride, promethazine hydrochloride, prochlorperazine maleate and chlorpromazine hydrochloride have been studied as indicators in bromate titration of quinol, metol and ascorbic acid. They give a very sharp reversible colour change at the equivalence point....

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Gowda HS, Ahmed SA. N-substituted phenothiazines as redox indicators in bromatometry. Talanta. 1979;26(3):233-5doi: 10.1016/0039-9140(79)80055-7.
Gowda, H. S., & Ahmed, S. A. (1979). N-substituted phenothiazines as redox indicators in bromatometry. Talanta, 26(3), 233-5. https://doi.org/10.1016/0039-9140(79)80055-7
Gowda, H S, and Ahmed, S A. "N-substituted phenothiazines as redox indicators in bromatometry." Talanta vol. 26,3 (1979): 233-5. doi: https://doi.org/10.1016/0039-9140(79)80055-7
Gowda HS, Ahmed SA. N-substituted phenothiazines as redox indicators in bromatometry. Talanta. 1979 Mar;26(3):233-5. doi: 10.1016/0039-9140(79)80055-7. PMID: 18962421.
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Enrichment techniques and trace analysis with microbore columns in liquid chromatography.

Journal of pharmaceutical and biomedical analysis

Krejci M, Slais K, Kourilová D, Vespalcová M.
PMID: 16867748
J Pharm Biomed Anal. 1984;2(2):197-205. doi: 10.1016/0731-7085(84)80071-0.

The advantages of microbore columns for trace analysis by liquid chromatography are identified, with reference to on-column enrichment techniques performed on analytical micro-columns. The selectivity and high sensitivity of the amperometric detector are utilized in combination with a microbore...

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Krejci M, Slais K, Kourilová D, et al. Enrichment techniques and trace analysis with microbore columns in liquid chromatography. J Pharm Biomed Anal. 1984;2(2):197-205doi: 10.1016/0731-7085(84)80071-0.
Krejci, M., Slais, K., Kourilová, D., & Vespalcová, M. (1984). Enrichment techniques and trace analysis with microbore columns in liquid chromatography. Journal of pharmaceutical and biomedical analysis, 2(2), 197-205. https://doi.org/10.1016/0731-7085(84)80071-0
Krejci, M, et al. "Enrichment techniques and trace analysis with microbore columns in liquid chromatography." Journal of pharmaceutical and biomedical analysis vol. 2,2 (1984): 197-205. doi: https://doi.org/10.1016/0731-7085(84)80071-0
Krejci M, Slais K, Kourilová D, Vespalcová M. Enrichment techniques and trace analysis with microbore columns in liquid chromatography. J Pharm Biomed Anal. 1984;2(2):197-205. doi: 10.1016/0731-7085(84)80071-0. PMID: 16867748.
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Pharmaceutical analysis of some tranquillizers and antidepressants with iodine monochloride.

Talanta

Beltagy YA, Issa AS, Mahrous MS.
PMID: 18962272
Talanta. 1978 Jun;25(6):349. doi: 10.1016/0039-9140(78)80140-4.

A titrimetric method for the evaluation of some tranquillizers and antidepressants is proposed. The method is based on the oxidation of these drugs by iodine monochloride, in strong acid medium, the iodine liberated being titrated with potassium iodate by...

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Beltagy YA, Issa AS, Mahrous MS. Pharmaceutical analysis of some tranquillizers and antidepressants with iodine monochloride. Talanta. 1978;25(6):349doi: 10.1016/0039-9140(78)80140-4.
Beltagy, Y. A., Issa, A. S., & Mahrous, M. S. (1978). Pharmaceutical analysis of some tranquillizers and antidepressants with iodine monochloride. Talanta, 25(6), 349. https://doi.org/10.1016/0039-9140(78)80140-4
Beltagy, Y A, et al. "Pharmaceutical analysis of some tranquillizers and antidepressants with iodine monochloride." Talanta vol. 25,6 (1978): 349. doi: https://doi.org/10.1016/0039-9140(78)80140-4
Beltagy YA, Issa AS, Mahrous MS. Pharmaceutical analysis of some tranquillizers and antidepressants with iodine monochloride. Talanta. 1978 Jun;25(6):349. doi: 10.1016/0039-9140(78)80140-4. PMID: 18962272.
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Extrapyramidal Syndrome Due to Phenothiazines.

Journal of the American Dental Society of Anesthesiology

[No authors listed]
PMID: 19599070
J Am Dent Soc Anesthesiol. 1965 Nov;12(9):286-7.

No abstract available.

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Extrapyramidal Syndrome Due to Phenothiazines. J Am Dent Soc Anesthesiol. 1965;12(9):286-7
(1965). Extrapyramidal Syndrome Due to Phenothiazines. Journal of the American Dental Society of Anesthesiology, 12(9), 286-7.
"Extrapyramidal Syndrome Due to Phenothiazines." Journal of the American Dental Society of Anesthesiology vol. 12,9 (1965): 286-7.
Extrapyramidal Syndrome Due to Phenothiazines. J Am Dent Soc Anesthesiol. 1965 Nov;12(9):286-7. PMID: 19599070; PMCID: PMC2033282.
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Sensitive determination of phenothiazines in pharmaceutical preparation and biological fluid by flow injection chemiluminescence method using luminol-KMnO(4) system.

Talanta

Li Y, Niu W, Lu J.
PMID: 19071422
Talanta. 2007 Feb 28;71(3):1124-9. doi: 10.1016/j.talanta.2006.06.007. Epub 2006 Jul 17.

A flow injection chemiluminescence method was described for the determination of four phenothiazine drugs, namely, chlorpromazine hydrochloride, perphenazine hydrochloride, fluphenazine hydrochloride and thioridazine hydrochloride. Strong Chemiluminescence (CL) signal was produced when above-mentioned drug was injected into the mixed stream...

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Li Y, Niu W, Lu J. Sensitive determination of phenothiazines in pharmaceutical preparation and biological fluid by flow injection chemiluminescence method using luminol-KMnO(4) system. Talanta. 2006;71(3):1124-9doi: 10.1016/j.talanta.2006.06.007.
Li, Y., Niu, W., & Lu, J. (2007). Sensitive determination of phenothiazines in pharmaceutical preparation and biological fluid by flow injection chemiluminescence method using luminol-KMnO(4) system. Talanta, 71(3), 1124-9. https://doi.org/10.1016/j.talanta.2006.06.007
Li, Yinhuan, et al. "Sensitive determination of phenothiazines in pharmaceutical preparation and biological fluid by flow injection chemiluminescence method using luminol-KMnO(4) system." Talanta vol. 71,3 (2007): 1124-9. doi: https://doi.org/10.1016/j.talanta.2006.06.007
Li Y, Niu W, Lu J. Sensitive determination of phenothiazines in pharmaceutical preparation and biological fluid by flow injection chemiluminescence method using luminol-KMnO(4) system. Talanta. 2007 Feb 28;71(3):1124-9. doi: 10.1016/j.talanta.2006.06.007. Epub 2006 Jul 17. PMID: 19071422.
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A Side Effect of Phenothiazines.

Canadian Medical Association journal

[No authors listed]
PMID: 20328012
Can Med Assoc J. 1964 Nov 14;91(20):1081.

No abstract available.

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A Side Effect of Phenothiazines. Can Med Assoc J. 1964;91(20):1081
(1964). A Side Effect of Phenothiazines. Canadian Medical Association journal, 91(20), 1081.
"A Side Effect of Phenothiazines." Canadian Medical Association journal vol. 91,20 (1964): 1081.
A Side Effect of Phenothiazines. Can Med Assoc J. 1964 Nov 14;91(20):1081. PMID: 20328012; PMCID: PMC1928289.
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Review: phenothiazines relieve acute migraine headaches in the ED and are better than other active agents for some outcomes.

Annals of internal medicine

Friedman BW.
PMID: 20404368
Ann Intern Med. 2010 Apr 20;152(8):JC4-11. doi: 10.7326/0003-4819-152-8-201004200-02011.

No abstract available.

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Friedman BW. Review: phenothiazines relieve acute migraine headaches in the ED and are better than other active agents for some outcomes. Ann Intern Med. 2010;152(8):JC4-11doi: 10.7326/0003-4819-152-8-201004200-02011.
Friedman, B. W. (2010). Review: phenothiazines relieve acute migraine headaches in the ED and are better than other active agents for some outcomes. Annals of internal medicine, 152(8), JC4-11. https://doi.org/10.7326/0003-4819-152-8-201004200-02011
Friedman, Benjamin W. "Review: phenothiazines relieve acute migraine headaches in the ED and are better than other active agents for some outcomes." Annals of internal medicine vol. 152,8 (2010): JC4-11. doi: https://doi.org/10.7326/0003-4819-152-8-201004200-02011
Friedman BW. Review: phenothiazines relieve acute migraine headaches in the ED and are better than other active agents for some outcomes. Ann Intern Med. 2010 Apr 20;152(8):JC4-11. doi: 10.7326/0003-4819-152-8-201004200-02011. PMID: 20404368.
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Showing 1 to 12 of 162 entries