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Showing 1 to 12 of 88 entries
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Delirium Accompanied by Cholinergic Deficiency and Organ Failure in a 73-Year-Old Critically Ill Patient: Physostigmine as a Therapeutic Option.

Case reports in critical care

Zujalovic B, Barth E.
PMID: 26550498
Case Rep Crit Care. 2015;2015:793015. doi: 10.1155/2015/793015. Epub 2015 Oct 13.

Delirium is a common problem in ICU patients, resulting in prolonged ICU stay and increased mortality. A cholinergic deficiency in the central nervous system is supposed to be a relevant pathophysiologic process in delirium. Acetylcholine is a major transmitter...

Response to Combination Cholinergic/Noradrenergic Treatments in a Patient With Alzheimer's Disease.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Aisen PS, Bierer LM, Davidson M, Ryan TM, Kaminsky R, Davis KL.
PMID: 28530925
Am J Geriatr Psychiatry. 1993 Summer;1(3):244-248. doi: 10.1097/00019442-199300130-00009. Epub 2013 Jan 28.

A patient with probable Alzheimer's disease participated in four studies involving cholinergic and combination cholinergic/noradrenergic treatment regimens. This patient demonstrated clinically significant improvement only with the combination of physostigmine and clonidine. The implications of these findings are discussed with...

Recovery of metabolic activity in retinofugal targets after traumatic optic nerve injury is independent of retinofugal input.

Restorative neurology and neuroscience

Schmitt U, Sabel BA, Cross R, Samson FE, Pazdernik TL.
PMID: 12671276
Restor Neurol Neurosci. 1998;13(3):153-61.

Traumatic injury of the adult optic nerve causes a progressive degeneration of retinal ganglion cells. Despite this ongoing degeneration, a partial recovery of visual behavioral function and of local cerebral glucose use (LCGU) has been observed. To evaluate whether...

Clinical signs and studies of the site of action of purified larkspur alkaloid, methyllycaconitine, administered parenterally to calves.

The Canadian veterinary journal = La revue veterinaire canadienne

Nation PN, Benn MH, Roth SH, Wilkens JL.
PMID: 17422179
Can Vet J. 1982 Sep;23(9):264-6.

The purified diterpenoid alkaloid, methyllycaconitine was isolated from Delphinium brownii and injected intravenously into beef calves in order to observe the clinical signs. Following injection and depending upon dosage, calves showed a variety of signs; agitation, respiratory difficulty and...

The action of atropine, pilocarpine and physostigmine.

The Journal of physiology

Cushny AR.
PMID: 16993048
J Physiol. 1910 Nov 09;41(3):233-45. doi: 10.1113/jphysiol.1910.sp001400.

No abstract available.

Photometric determination of physostigmine.

Farmacevtisk revy

EHRLEN I.
PMID: 18884016
Farm Revy. 1948 Aug 07;47(32):519-24.

No abstract available.

Liquid chromatographic determination of the pH-dependent degradation of eseroline--hydrolysis product of physostigmine.

Journal of pharmaceutical and biomedical analysis

Yang ST, Wilken LO, Clark CR.
PMID: 16867508
J Pharm Biomed Anal. 1987;5(4):383-93. doi: 10.1016/0731-7085(87)80045-6.

The stability of eseroline, the hydrolysis product of physostigmine under aerobic conditions, was studied by liquid chromatography. A reversed-phase, ion-pair technique was used to separate eseroline from its degradation products. The degradation of eseroline in phosphate buffer solutions of...

Peripubertal and adult male rats differ in their hypothalamic-pituitary response to cholinergic challenge.

Journal of child and adolescent psychopharmacology

McCracken JT, Poland RE.
PMID: 19630662
J Child Adolesc Psychopharmacol. 1990;1(2):141-5. doi: 10.1089/cap.1990.1.141.

ABSTRACT The influence of pubertal development on the cholinergic regulation of adrenocorticotropin (ACTH) was examined by measuring the ACTH response to the cholinergic agonist physostigmine in peripubertal and adult male rats. Adult animals showed significantly greater ACTH responses to...

Investigations of the cholinergic deficit hypothesis in the hippocampus of the aged rat brain with physostigmine and scopolamine.

Archives of gerontology and geriatrics

Meier-Ruge W, Kolbe M, Sattler J.
PMID: 15374451
Arch Gerontol Geriatr. 1991 Mar-Jun;12(2):239-51. doi: 10.1016/0167-4943(91)90031-k.

Using histochemically demonstrated acetylcholinesterase activity and (14)C-2-deoxyglucose uptake as the respective indices, a study was set up to determine whether cerebral (hippocampal) metabolism was stimulated by a cholinergic agonist and/or inhibited by a cholinergic antagonist. For this 36 12-month-old...

Differences between Physostigmine- and Yohimbine-induced States Are Visualized in Canonical Space Constructed from EEG during Natural Sleep-wake Cycle in Rats.

Experimental neurobiology

Lee MG, Kim M, Roh M, Jang IS, Won SH.
PMID: 22110362
Exp Neurobiol. 2011 Mar;20(1):54-65. doi: 10.5607/en.2011.20.1.54. Epub 2011 Mar 31.

Although quantitative EEG parameters, such as spectral band powers, are sensitive to centrally acting drugs in dose- and time-related manners, changes of the EEG parameters are redundant. It is desirable to reduce multiple EEG parameters to a few components...

Drug-induced arterial hypertension - a frequently ignored cause of secondary hypertension: a review.

Acta cardiologica

Diaconu CC, Dediu GN, Iancu MA.
PMID: 29291681
Acta Cardiol. 2018 Jan 01;1-7. doi: 10.1080/00015385.2017.1421445. Epub 2018 Jan 01.

The prevalence of hypertension is likely to grow during the future years, mainly due to aging of the population and increasing prevalence of obesity, as an important risk factor for hypertension. One of the main causes of secondary hypertension,...

Clinicobiochemical changes in ivermectin toxicity in Doberman pinscher pups.

Journal of parasitic diseases : official organ of the Indian Society for Parasitology

Dey S, Kurade NP, Khurana KL, Dan A.
PMID: 28615883
J Parasit Dis. 2017 Jun;41(2):580-583. doi: 10.1007/s12639-016-0806-1. Epub 2016 Jun 30.

This study is based on naturally intoxicated Doberman pinscher pups. Six Doberman pinscher pups were overdosed 50 times of recommended ivermectin dose by the pet owner and presented to Referral Veterinary Polyclinic section of this institute in a state...

Showing 1 to 12 of 88 entries