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Showing 1 to 12 of 12 entries
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Topographical Association of the Platelet Fc-receptor with the Glycoprotein IIb-IIIa Complex.

Platelets

Berndt MC, Mazurov AV, Vinogradov DV, Burns GF, Chesterman CN.
PMID: 21043840
Platelets. 1993;4(4):190-6. doi: 10.3109/09537109309013216.

In this study, we have examined whether the platelet Fc-receptor, FcγRII (CD32), is associated with either of the two major platelet membrane glycoproteins, the GPIb-IX complex and the GPIIb-IIIa complex. Monoclonal and polyclonal anti-GPIb-IX complex antibodies inhibited to only...

Molecular typing of human platelet antigens in immune thrombocytopenia patients in northern Brazil.

Revista brasileira de hematologia e hemoterapia

Carmo JCD, Klippel PS, Cordeiro SDC, Fernandes ÂMDS, Pinto RM, Weber SS, Fantin C.
PMID: 28577648
Rev Bras Hematol Hemoter. 2017 Apr - Jun;39(2):122-126. doi: 10.1016/j.bjhh.2017.01.003. Epub 2017 Feb 22.

BACKGROUND: Immune thrombocytopenia is an immune disease characterized by thrombocytopenia and bleeding due to platelet antibodies against platelet membrane glycoproteins. Human platelet antigens are derived from polymorphisms of these glycoproteins. The aim of this study was to investigate human...

The Molecular Genetics of Platelet Membrane Proteins and their Inherited Disorders.

Platelets

Cooper DN.
PMID: 21047281
Platelets. 1991;2(2):59-67. doi: 10.3109/09537109109113690.

The platelet membrane glycoproteins fulfil a vital function in platelet adhesion and aggrkgation. The advent of recombinant DNA technology has provided a wealth of new information on the sequence, structure, expression and chromosomal location of the genes encoding these...

A new variant of Glanzmann's thrombasthenia with defective activation-dependent fibrinogen binding and altered expression of epitopes for several monoclonal antibodies against GP IIb-IIIa.

Platelets

Meyer M, Thieme A, Jablonka B, Just M, Ströhl C, Schellenberg I, Kirchmaier CM.
PMID: 21043690
Platelets. 1996;7(4):215-24. doi: 10.3109/09537109609023581.

In a family, a moderate bleeding disorder in two patients has been specified as Glanzmann's thrombasthenia because of characteristic defects in platelet function. Analysis of platelet membrane glycoproteins revealed about a 50% decrease in the amount of GP IIb-IIIa...

Drug-induced Immune Thrombocytopenia.

Platelets

Chong BH.
PMID: 21043926
Platelets. 1991;2(4):173-81. doi: 10.3109/09537109109005508.

SUMMARY. Immune thrombocytopenia is a relatively common problem associated with the clinical usage of drugs. Drugs frequently implicated include quinine, quinidine, heparin, penicillins, cephalosporins, co-trimoxazole, gold and D-penicillamine. Bleeding including bruising and purpura is the usual clinical manifestation except...

Anti-glycoprotein VI mediated immune thrombocytopenia: An under-recognized and significant entity?.

Research and practice in thrombosis and haemostasis

Rabbolini DJ, Gardiner EE, Morel-Kopp MC, Dunkley S, Jahangiri A, Lee CS, Stevenson WS, Ward CM.
PMID: 30046699
Res Pract Thromb Haemost. 2017 Aug 24;1(2):291-295. doi: 10.1002/rth2.12033. eCollection 2017 Oct.

Idiopathic immune thrombocytopenia (ITP) is an autoimmune disorder characterized by relapsing/ remitting thrombocytopenia. Bleeding complications are infrequent with platelet counts above 30×10

Thrombus management during direct coronary intervention for acute myocardial infarction.

American journal of translational research

Geng T, Song Z, Wang B, Dai S, Xu Z.
PMID: 34306427
Am J Transl Res. 2021 Jun 15;13(6):6784-6789. eCollection 2021.

OBJECTIVE: To study the management of thrombus during direct coronary intervention in patients with acute myocardial infarction (AMI).METHODS: We retrospectively analyzed 332 acute myocardial infarction patients receiving coronary artery intervention in our hospital from May 2017 to May 2019....

Expression of the 60 kDa and 71 kDa heat shock proteins and presence of antibodies against the 71 kDa heat shock protein in pediatric patients with immune thrombocytopenic purpura.

BMC blood disorders

Xiao C, Chen S, Yuan M, Ding F, Yang D, Wang R, Li J, Tanguay RM, Wu T.
PMID: 15070425
BMC Blood Disord. 2004 Mar 02;4:1. doi: 10.1186/1471-2326-4-1. eCollection 2004.

BACKGROUND: Immune thrombocytopenic purpura (ITP) is an autoimmune disease characterized by platelet destruction resulting from autoantibodies against platelet proteins, particularly platelet glycoprotein IIb/IIIa. Heat shock proteins (Hsp) have been shown to be major antigenic determinants in some autoimmune diseases....

Inhibitory role of S-nitrosoglutathione in the aggregation of frozen platelets, and its effect on the expression of membrane glycoproteins.

Experimental and therapeutic medicine

Wu T, Zhang C, Wang Z, Liu J, Li H, Zhou W, Wang S.
PMID: 24137275
Exp Ther Med. 2013 Sep;6(3):831-839. doi: 10.3892/etm.2013.1221. Epub 2013 Jul 12.

The aim of this study was to explore the effects of S-nitrosoglutathione (GSNO) on the aggregation of frozen platelets, the platelet nitric oxide (NO) content and the expression of membrane glycoproteins. The level of frozen platelet aggregation was measured...

A Case of Confirmed Ceftriaxone-induced Immune Thrombocytopenia.

Cureus

Piedra Abusharar S, Shah N, Patel R, Jain R, Polimera HV.
PMID: 31338265
Cureus. 2019 May 17;11(5):e4688. doi: 10.7759/cureus.4688.

Drug-induced immune thrombocytopenia (DITP) is a rare, but potentially fatal cause of isolated thrombocytopenia. DITP is thought to occur when drug-dependent antibodies bind to the platelet membrane glycoproteins to activate platelet consumption signaling. Common implicated drugs include quinine/quinidine, penicillamines,...

Platelet receptors for collagens.

Platelets

Kehrel B.
PMID: 21043583
Platelets. 1995;6(1):11-6. doi: 10.3109/09537109509013256.

Collagens belong to the constituents that determine the thrombogenicity of the vessel wall. Seven genetically distinct collagens-type I, III, IV, V, VI, VIII and XIII-have been identified in the vessel wall. The interaction of platelets with collagens is a...

Evaluation of platelet membrane glycoproteins in coronary artery disease : consequences for diagnosis and therapy .

Circulation

Gawaz M, Neumann FJ, Schomig A.
PMID: 9884400
Circulation. 1999 Jan 05;99(1):E1-E11. doi: 10.1161/01.cir.99.1.e1.

No abstract available.

Showing 1 to 12 of 12 entries