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Lack of an association between SNPs within the cholinergic receptor genes and smoking behavior in a Czech post-MONICA study.

Genetics and molecular biology

Hubacek JA, Lanska V, Adamkova V.
PMID: 25505836
Genet Mol Biol. 2014 Oct;37(4):625-30. doi: 10.1590/S1415-47572014005000023. Epub 2014 Nov 14.

Smoking has a significant heritable component of approximately 30-60%. Recent genome wide association studies have identified single nucleotide polymorphisms (SNPs) within the nicotinic cholinergic receptor subunits 3 (rs578776), 5 (rs16969968) and β3 (rs6474412), which are associated with nicotine dependence...

Oxidative stress and the cholinergic system in non-segmental vitiligo: Effect of narrow band ultraviolet b.

Photodermatology, photoimmunology & photomedicine

Said ER, Nagui NAER, Rashed LA, Mostafa WZ.
PMID: 33404131
Photodermatol Photoimmunol Photomed. 2021 Jul;37(4):306-312. doi: 10.1111/phpp.12653. Epub 2021 Jan 16.

BACKGROUND: Despite exhaustive research, melanocyte disappearance and the evolution of vitiligo remain enigmatic, and although multi-factorial, oxidative stress appears as a major player. The role of cutaneous cholinergic system in vitiligo pathogenesis has also been reported in some studies.OBJECTIVE:...

Nicotinic receptors in neurodegeneration.

Current neuropharmacology

Posadas I, López-Hernández B, Ceña V.
PMID: 24179465
Curr Neuropharmacol. 2013 May;11(3):298-314. doi: 10.2174/1570159X11311030005.

Many studies have focused on expanding our knowledge of the structure and diversity of peripheral and central nicotinic receptors. Nicotinic acetylcholine receptors (nAChRs) are members of the Cys-loop superfamily of pentameric ligand-gated ion channels, which include GABA (A and...

Showing 1 to 3 of 3 entries