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Of monkeys and men: immunomic profiling of sera from humans and non-human primates resistant to schistosomiasis reveals novel potential vaccine candidates.

Frontiers in immunology

Pearson MS, Becker L, Driguez P, Young ND, Gaze S, Mendes T, Li XH, Doolan DL, Midzi N, Mduluza T, McManus DP, Wilson RA, Bethony JM, Nausch N, Mutapi F, Felgner PL, Loukas A.
PMID: 25999951
Front Immunol. 2015 May 05;6:213. doi: 10.3389/fimmu.2015.00213. eCollection 2015.

Schistosoma haematobium affects more than 100 million people throughout Africa and is the causative agent of urogenital schistosomiasis. The parasite is strongly associated with urothelial cancer in infected individuals and as such is designated a group I carcinogen by...

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Pearson MS, Becker L, Driguez P, et al. Of monkeys and men: immunomic profiling of sera from humans and non-human primates resistant to schistosomiasis reveals novel potential vaccine candidates. Front Immunol. 2015;6:213doi: 10.3389/fimmu.2015.00213.
Pearson, M. S., Becker, L., Driguez, P., Young, N. D., Gaze, S., Mendes, T., Li, X. H., Doolan, D. L., Midzi, N., Mduluza, T., McManus, D. P., Wilson, R. A., Bethony, J. M., Nausch, N., Mutapi, F., Felgner, P. L., & Loukas, A. (2015). Of monkeys and men: immunomic profiling of sera from humans and non-human primates resistant to schistosomiasis reveals novel potential vaccine candidates. Frontiers in immunology, 6213. https://doi.org/10.3389/fimmu.2015.00213
Pearson, Mark S, et al. "Of monkeys and men: immunomic profiling of sera from humans and non-human primates resistant to schistosomiasis reveals novel potential vaccine candidates." Frontiers in immunology vol. 6 (2015): 213. doi: https://doi.org/10.3389/fimmu.2015.00213
Pearson MS, Becker L, Driguez P, Young ND, Gaze S, Mendes T, Li XH, Doolan DL, Midzi N, Mduluza T, McManus DP, Wilson RA, Bethony JM, Nausch N, Mutapi F, Felgner PL, Loukas A. Of monkeys and men: immunomic profiling of sera from humans and non-human primates resistant to schistosomiasis reveals novel potential vaccine candidates. Front Immunol. 2015 May 05;6:213. doi: 10.3389/fimmu.2015.00213. eCollection 2015. PMID: 25999951; PMCID: PMC4419842.
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Association of GSTO1 and GSTO2 Polymorphism with Risk of End-Stage Renal Disease Development and Patient Survival.

Journal of medical biochemistry

Cimbaljevic S, Suvakov S, Matic M, Pljesa-Ercegovac M, Pekmezovic T, Radic T, Coric V, Damjanovic T, Dimkovic N, Markovic R, Savic-Radojevic A, Simic T.
PMID: 28356881
J Med Biochem. 2016 Sep;35(3):302-311. doi: 10.1515/jomb-2016-0009. Epub 2016 Jul 06.

BACKGROUND: Oxidative stress in patients with end-stage renal disease (ESRD) is associated with long-term cardiovascular complications. The cytosolic family of glutathione S-transferases (GSTs) is involved in the detoxication of various toxic compounds and antioxidant protection. GST omega class members,...

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Cimbaljevic S, Suvakov S, Matic M, et al. Association of GSTO1 and GSTO2 Polymorphism with Risk of End-Stage Renal Disease Development and Patient Survival. J Med Biochem. 2016;35(3):302-311doi: 10.1515/jomb-2016-0009.
Cimbaljevic, S., Suvakov, S., Matic, M., Pljesa-Ercegovac, M., Pekmezovic, T., Radic, T., Coric, V., Damjanovic, T., Dimkovic, N., Markovic, R., Savic-Radojevic, A., & Simic, T. (2016). Association of GSTO1 and GSTO2 Polymorphism with Risk of End-Stage Renal Disease Development and Patient Survival. Journal of medical biochemistry, 35(3), 302-311. https://doi.org/10.1515/jomb-2016-0009
Cimbaljevic, Slavica, et al. "Association of GSTO1 and GSTO2 Polymorphism with Risk of End-Stage Renal Disease Development and Patient Survival." Journal of medical biochemistry vol. 35,3 (2016): 302-311. doi: https://doi.org/10.1515/jomb-2016-0009
Cimbaljevic S, Suvakov S, Matic M, Pljesa-Ercegovac M, Pekmezovic T, Radic T, Coric V, Damjanovic T, Dimkovic N, Markovic R, Savic-Radojevic A, Simic T. Association of GSTO1 and GSTO2 Polymorphism with Risk of End-Stage Renal Disease Development and Patient Survival. J Med Biochem. 2016 Sep;35(3):302-311. doi: 10.1515/jomb-2016-0009. Epub 2016 Jul 06. PMID: 28356881; PMCID: PMC5346808.
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Genetic polymorphism of glutathione S-transferase P1 (GSTP1) in Delhi population and comparison with other global populations.

Meta gene

Sharma A, Pandey A, Sharma S, Chatterjee I, Mehrotra R, Sehgal A, Sharma JK.
PMID: 25606397
Meta Gene. 2014 Jan 20;2:134-42. doi: 10.1016/j.mgene.2013.12.003. eCollection 2014 Dec.

Glutathione S-transferases (GSTs) belong to a super family of phase II detoxification enzymes, which play an important role in protecting cells from damage caused by endogenous and exogenous compounds by conjugating reactive intermediates with glutathione to produce less reactive...

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Sharma A, Pandey A, Sharma S, et al. Genetic polymorphism of glutathione S-transferase P1 (GSTP1) in Delhi population and comparison with other global populations. Meta Gene. 2014;2:134-42doi: 10.1016/j.mgene.2013.12.003.
Sharma, A., Pandey, A., Sharma, S., Chatterjee, I., Mehrotra, R., Sehgal, A., & Sharma, J. K. (2014). Genetic polymorphism of glutathione S-transferase P1 (GSTP1) in Delhi population and comparison with other global populations. Meta gene, 2134-42. https://doi.org/10.1016/j.mgene.2013.12.003
Sharma, Anita, et al. "Genetic polymorphism of glutathione S-transferase P1 (GSTP1) in Delhi population and comparison with other global populations." Meta gene vol. 2 (2014): 134-42. doi: https://doi.org/10.1016/j.mgene.2013.12.003
Sharma A, Pandey A, Sharma S, Chatterjee I, Mehrotra R, Sehgal A, Sharma JK. Genetic polymorphism of glutathione S-transferase P1 (GSTP1) in Delhi population and comparison with other global populations. Meta Gene. 2014 Jan 20;2:134-42. doi: 10.1016/j.mgene.2013.12.003. eCollection 2014 Dec. PMID: 25606397; PMCID: PMC4287809.
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The effect of GSTT1, GSTM1 and GSTP1 gene polymorphisms on the susceptibility of age-related cataract in Chinese Han population.

International journal of clinical and experimental medicine

Qi R, Gu Z, Zhou L.
PMID: 26770590
Int J Clin Exp Med. 2015 Oct 15;8(10):19448-53. eCollection 2015.

OBJECTIVE: Age-related cataract (ARC) is one of the most common eye diseases in the elderly worldwide, especially in China. The genetic polymorphisms of many glutathione S-transferases coding genes are likely to be closely related to the development of ARC,...

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Qi R, Gu Z, Zhou L. The effect of GSTT1, GSTM1 and GSTP1 gene polymorphisms on the susceptibility of age-related cataract in Chinese Han population. Int J Clin Exp Med. 2015;8(10):19448-53
Qi, R., Gu, Z., & Zhou, L. (2015). The effect of GSTT1, GSTM1 and GSTP1 gene polymorphisms on the susceptibility of age-related cataract in Chinese Han population. International journal of clinical and experimental medicine, 8(10), 19448-53.
Qi, Ruo, et al. "The effect of GSTT1, GSTM1 and GSTP1 gene polymorphisms on the susceptibility of age-related cataract in Chinese Han population." International journal of clinical and experimental medicine vol. 8,10 (2015): 19448-53.
Qi R, Gu Z, Zhou L. The effect of GSTT1, GSTM1 and GSTP1 gene polymorphisms on the susceptibility of age-related cataract in Chinese Han population. Int J Clin Exp Med. 2015 Oct 15;8(10):19448-53. eCollection 2015. PMID: 26770590; PMCID: PMC4694490.
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Sexual Dimorphism in the Response of Mercurialis annua to Stress.

Metabolites

Orlofsky EM, Kozhoridze G, Lyubenova L, Ostrozhenkova E, Winkler JB, Schröder P, Bacher A, Eisenreich W, Guy M, Golan-Goldhirsh A.
PMID: 27128954
Metabolites. 2016 Apr 26;6(2). doi: 10.3390/metabo6020013.

The research presented stemmed from the observations that female plants of the annual dioecious Mercurialis annua outlive male plants. This led to the hypothesis that female plants of M. annua would be more tolerant to stress than male plants....

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Orlofsky EM, Kozhoridze G, Lyubenova L, et al. Sexual Dimorphism in the Response of Mercurialis annua to Stress. Metabolites. 2016;6(2)doi: 10.3390/metabo6020013.
Orlofsky, E. M., Kozhoridze, G., Lyubenova, L., Ostrozhenkova, E., Winkler, J. B., Schröder, P., Bacher, A., Eisenreich, W., Guy, M., & Golan-Goldhirsh, A. (2016). Sexual Dimorphism in the Response of Mercurialis annua to Stress. Metabolites, 6(2), . https://doi.org/10.3390/metabo6020013
Orlofsky, Ezra M, et al. "Sexual Dimorphism in the Response of Mercurialis annua to Stress." Metabolites vol. 6,2 (2016). doi: https://doi.org/10.3390/metabo6020013
Orlofsky EM, Kozhoridze G, Lyubenova L, Ostrozhenkova E, Winkler JB, Schröder P, Bacher A, Eisenreich W, Guy M, Golan-Goldhirsh A. Sexual Dimorphism in the Response of Mercurialis annua to Stress. Metabolites. 2016 Apr 26;6(2). doi: 10.3390/metabo6020013. PMID: 27128954; PMCID: PMC4931544.
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Biomarkers of exposure, effect, and susceptibility in workers exposed to chloronitrobenzenes.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals

Sabbioni G, Norppa H, Hirvonen A, Järventaus H, Jones CR, Yan H, Sepai O.
PMID: 27121198
Biomarkers. 2016 Dec;21(8):721-730. doi: 10.3109/1354750X.2016.1172116. Epub 2016 Apr 27.

Biomonitoring methods were applied to workers exposed to high levels of chloronitrobenzenes. The external dose, internal dose, biologically effective dose, and biological effects were determined. Individual susceptibility was assessed by analyzing genetic polymorphisms of glutathione S-transferases M1, P1 and...

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Sabbioni G, Norppa H, Hirvonen A, et al. Biomarkers of exposure, effect, and susceptibility in workers exposed to chloronitrobenzenes. Biomarkers. 2016;21(8):721-730doi: 10.3109/1354750X.2016.1172116.
Sabbioni, G., Norppa, H., Hirvonen, A., Järventaus, H., Jones, C. R., Yan, H., & Sepai, O. (2016). Biomarkers of exposure, effect, and susceptibility in workers exposed to chloronitrobenzenes. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 21(8), 721-730. https://doi.org/10.3109/1354750X.2016.1172116
Sabbioni, Gabriele, et al. "Biomarkers of exposure, effect, and susceptibility in workers exposed to chloronitrobenzenes." Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals vol. 21,8 (2016): 721-730. doi: https://doi.org/10.3109/1354750X.2016.1172116
Sabbioni G, Norppa H, Hirvonen A, Järventaus H, Jones CR, Yan H, Sepai O. Biomarkers of exposure, effect, and susceptibility in workers exposed to chloronitrobenzenes. Biomarkers. 2016 Dec;21(8):721-730. doi: 10.3109/1354750X.2016.1172116. Epub 2016 Apr 27. PMID: 27121198.
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The poplar Phi class glutathione transferase: expression, activity and structure of GSTF1.

Frontiers in plant science

Pégeot H, Koh CS, Petre B, Mathiot S, Duplessis S, Hecker A, Didierjean C, Rouhier N.
PMID: 25566286
Front Plant Sci. 2014 Dec 23;5:712. doi: 10.3389/fpls.2014.00712. eCollection 2014.

Glutathione transferases (GSTs) constitute a superfamily of enzymes with essential roles in cellular detoxification and secondary metabolism in plants as in other organisms. Several plant GSTs, including those of the Phi class (GSTFs), require a conserved catalytic serine residue...

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Pégeot H, Koh CS, Petre B, et al. The poplar Phi class glutathione transferase: expression, activity and structure of GSTF1. Front Plant Sci. 2014;5:712doi: 10.3389/fpls.2014.00712.
Pégeot, H., Koh, C. S., Petre, B., Mathiot, S., Duplessis, S., Hecker, A., Didierjean, C., & Rouhier, N. (2014). The poplar Phi class glutathione transferase: expression, activity and structure of GSTF1. Frontiers in plant science, 5712. https://doi.org/10.3389/fpls.2014.00712
Pégeot, Henri, et al. "The poplar Phi class glutathione transferase: expression, activity and structure of GSTF1." Frontiers in plant science vol. 5 (2014): 712. doi: https://doi.org/10.3389/fpls.2014.00712
Pégeot H, Koh CS, Petre B, Mathiot S, Duplessis S, Hecker A, Didierjean C, Rouhier N. The poplar Phi class glutathione transferase: expression, activity and structure of GSTF1. Front Plant Sci. 2014 Dec 23;5:712. doi: 10.3389/fpls.2014.00712. eCollection 2014. PMID: 25566286; PMCID: PMC4274894.
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Association of glutathione S-transferase (GSTM1 and GSTT1) genes with chronic myeloid leukemia.

SpringerPlus

Kassogue Y, Dehbi H, Quachouh M, Quessar A, Benchekroun S, Nadifi S.
PMID: 25969820
Springerplus. 2015 May 01;4:210. doi: 10.1186/s40064-015-0966-y. eCollection 2015.

Chronic myeloid leukemia (CML), as most of cancers results from a complex interaction between genetic or non genetic factors. Exposures to xenobiotics endogenous or exogenous associated with a reduced individual ability in detoxifying activity, constitutes a risk of developing...

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Kassogue Y, Dehbi H, Quachouh M, et al. Association of glutathione S-transferase (GSTM1 and GSTT1) genes with chronic myeloid leukemia. Springerplus. 2015;4:210doi: 10.1186/s40064-015-0966-y.
Kassogue, Y., Dehbi, H., Quachouh, M., Quessar, A., Benchekroun, S., & Nadifi, S. (2015). Association of glutathione S-transferase (GSTM1 and GSTT1) genes with chronic myeloid leukemia. SpringerPlus, 4210. https://doi.org/10.1186/s40064-015-0966-y
Kassogue, Yaya, et al. "Association of glutathione S-transferase (GSTM1 and GSTT1) genes with chronic myeloid leukemia." SpringerPlus vol. 4 (2015): 210. doi: https://doi.org/10.1186/s40064-015-0966-y
Kassogue Y, Dehbi H, Quachouh M, Quessar A, Benchekroun S, Nadifi S. Association of glutathione S-transferase (GSTM1 and GSTT1) genes with chronic myeloid leukemia. Springerplus. 2015 May 01;4:210. doi: 10.1186/s40064-015-0966-y. eCollection 2015. PMID: 25969820; PMCID: PMC4417468.
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Messenger RNA encoding a glutathione-S-transferase responsible for herbicide tolerance in maize is induced in response to safener treatment.

Plant molecular biology

Wiegand RC, Shah DM, Mozer TJ, Harding EI, Diaz-Collier J, Saunders C, Jaworski EG, Tiemeier DC.
PMID: 24302366
Plant Mol Biol. 1986 Jul;7(4):235-43. doi: 10.1007/BF00752897.

Glutathione-S-transferases (GST's) in maize represent a family of enzymes which conjugate glutathione to several major classes of pre-emergent, selective herbicides. Chemicals termed safeners have been demonstrated to increase the tolerance of maize toward such herbicides when the maize seed...

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Wiegand RC, Shah DM, Mozer TJ, et al. Messenger RNA encoding a glutathione-S-transferase responsible for herbicide tolerance in maize is induced in response to safener treatment. Plant Mol Biol. 1986;7(4):235-43doi: 10.1007/BF00752897.
Wiegand, R. C., Shah, D. M., Mozer, T. J., Harding, E. I., Diaz-Collier, J., Saunders, C., Jaworski, E. G., & Tiemeier, D. C. (1986). Messenger RNA encoding a glutathione-S-transferase responsible for herbicide tolerance in maize is induced in response to safener treatment. Plant molecular biology, 7(4), 235-43. https://doi.org/10.1007/BF00752897
Wiegand, R C, et al. "Messenger RNA encoding a glutathione-S-transferase responsible for herbicide tolerance in maize is induced in response to safener treatment." Plant molecular biology vol. 7,4 (1986): 235-43. doi: https://doi.org/10.1007/BF00752897
Wiegand RC, Shah DM, Mozer TJ, Harding EI, Diaz-Collier J, Saunders C, Jaworski EG, Tiemeier DC. Messenger RNA encoding a glutathione-S-transferase responsible for herbicide tolerance in maize is induced in response to safener treatment. Plant Mol Biol. 1986 Jul;7(4):235-43. doi: 10.1007/BF00752897. PMID: 24302366.
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Predictive role of Glutathione S-transferases (GSTs) on the prognosis of osteosarcoma patients treated with chemotherapy.

Pakistan journal of medical sciences

Teng JW, Yang ZM, Li J, Xu B.
PMID: 24353716
Pak J Med Sci. 2013 Sep;29(5):1182-6. doi: 10.12669/pjms.295.3870.

OBJECTIVE: We conducted a comprehensive study to investigate the role of GSTM1, GSTTI and GSTP1 genetic variation involved in transport pathways in response to chemotherapy and clinical outcome of osteosarcoma.METHODS: A total of 146 patients were included in our...

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Teng JW, Yang ZM, Li J, et al. Predictive role of Glutathione S-transferases (GSTs) on the prognosis of osteosarcoma patients treated with chemotherapy. Pak J Med Sci. 2013;29(5):1182-6doi: 10.12669/pjms.295.3870.
Teng, J. W., Yang, Z. M., Li, J., & Xu, B. (2013). Predictive role of Glutathione S-transferases (GSTs) on the prognosis of osteosarcoma patients treated with chemotherapy. Pakistan journal of medical sciences, 29(5), 1182-6. https://doi.org/10.12669/pjms.295.3870
Teng, Jia-Wen, et al. "Predictive role of Glutathione S-transferases (GSTs) on the prognosis of osteosarcoma patients treated with chemotherapy." Pakistan journal of medical sciences vol. 29,5 (2013): 1182-6. doi: https://doi.org/10.12669/pjms.295.3870
Teng JW, Yang ZM, Li J, Xu B. Predictive role of Glutathione S-transferases (GSTs) on the prognosis of osteosarcoma patients treated with chemotherapy. Pak J Med Sci. 2013 Sep;29(5):1182-6. doi: 10.12669/pjms.295.3870. PMID: 24353716; PMCID: PMC3858940.
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Large-Scale Proteomics of the Cassava Storage Root and Identification of a Target Gene to Reduce Postharvest Deterioration.

The Plant cell

Vanderschuren H, Nyaboga E, Poon JS, Baerenfaller K, Grossmann J, Hirsch-Hoffmann M, Kirchgessner N, Nanni P, Gruissem W.
PMID: 24876255
Plant Cell. 2014 May;26(5):1913-1924. doi: 10.1105/tpc.114.123927. Epub 2014 May 29.

Cassava (Manihot esculenta) is the most important root crop in the tropics, but rapid postharvest physiological deterioration (PPD) of the root is a major constraint to commercial cassava production. We established a reliable method for image-based PPD symptom quantification...

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Vanderschuren H, Nyaboga E, Poon JS, et al. Large-Scale Proteomics of the Cassava Storage Root and Identification of a Target Gene to Reduce Postharvest Deterioration. Plant Cell. 2014;26(5):1913-1924doi: 10.1105/tpc.114.123927.
Vanderschuren, H., Nyaboga, E., Poon, J. S., Baerenfaller, K., Grossmann, J., Hirsch-Hoffmann, M., Kirchgessner, N., Nanni, P., & Gruissem, W. (2014). Large-Scale Proteomics of the Cassava Storage Root and Identification of a Target Gene to Reduce Postharvest Deterioration. The Plant cell, 26(5), 1913-1924. https://doi.org/10.1105/tpc.114.123927
Vanderschuren, Hervé, et al. "Large-Scale Proteomics of the Cassava Storage Root and Identification of a Target Gene to Reduce Postharvest Deterioration." The Plant cell vol. 26,5 (2014): 1913-1924. doi: https://doi.org/10.1105/tpc.114.123927
Vanderschuren H, Nyaboga E, Poon JS, Baerenfaller K, Grossmann J, Hirsch-Hoffmann M, Kirchgessner N, Nanni P, Gruissem W. Large-Scale Proteomics of the Cassava Storage Root and Identification of a Target Gene to Reduce Postharvest Deterioration. Plant Cell. 2014 May;26(5):1913-1924. doi: 10.1105/tpc.114.123927. Epub 2014 May 29. PMID: 24876255; PMCID: PMC4079358.
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Sulforaphane Reverses the Expression of Various Tumor Suppressor Genes by Targeting DNMT3B and HDAC1 in Human Cervical Cancer Cells.

Evidence-based complementary and alternative medicine : eCAM

Ali Khan M, Kedhari Sundaram M, Hamza A, Quraishi U, Gunasekera D, Ramesh L, Goala P, Al Alami U, Ansari MZ, Rizvi TA, Sharma C, Hussain A.
PMID: 26161119
Evid Based Complement Alternat Med. 2015;2015:412149. doi: 10.1155/2015/412149. Epub 2015 Jun 16.

Sulforaphane (SFN) may hinder carcinogenesis by altering epigenetic events in the cells; however, its molecular mechanisms are unclear. The present study investigates the role of SFN in modifying epigenetic events in human cervical cancer cells, HeLa. HeLa cells were...

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Ali Khan M, Kedhari Sundaram M, Hamza A, et al. Sulforaphane Reverses the Expression of Various Tumor Suppressor Genes by Targeting DNMT3B and HDAC1 in Human Cervical Cancer Cells. Evid Based Complement Alternat Med. 2015;2015:412149doi: 10.1155/2015/412149.
Ali Khan, M., Kedhari Sundaram, M., Hamza, A., Quraishi, U., Gunasekera, D., Ramesh, L., Goala, P., Al Alami, U., Ansari, M. Z., Rizvi, T. A., Sharma, C., & Hussain, A. (2015). Sulforaphane Reverses the Expression of Various Tumor Suppressor Genes by Targeting DNMT3B and HDAC1 in Human Cervical Cancer Cells. Evidence-based complementary and alternative medicine : eCAM, 2015412149. https://doi.org/10.1155/2015/412149
Ali Khan, Munawwar, et al. "Sulforaphane Reverses the Expression of Various Tumor Suppressor Genes by Targeting DNMT3B and HDAC1 in Human Cervical Cancer Cells." Evidence-based complementary and alternative medicine : eCAM vol. 2015 (2015): 412149. doi: https://doi.org/10.1155/2015/412149
Ali Khan M, Kedhari Sundaram M, Hamza A, Quraishi U, Gunasekera D, Ramesh L, Goala P, Al Alami U, Ansari MZ, Rizvi TA, Sharma C, Hussain A. Sulforaphane Reverses the Expression of Various Tumor Suppressor Genes by Targeting DNMT3B and HDAC1 in Human Cervical Cancer Cells. Evid Based Complement Alternat Med. 2015;2015:412149. doi: 10.1155/2015/412149. Epub 2015 Jun 16. PMID: 26161119; PMCID: PMC4487331.
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