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Showing 1 to 12 of 492 entries
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Bioactive compounds in green tea leaves attenuate the injury of retinal ganglion RGC-5 cells induced by H2O2 and ultraviolet radiation.

Pakistan journal of pharmaceutical sciences

Jin J, Ying H, Huang M, Du Q.
PMID: 26687755
Pak J Pharm Sci. 2015 Nov;28(6):2267-72.

The Chinese commonly believe that tea helps maintain clear vision. This viewpoint has been recorded in Chinese medical books also. The key bioactive compounds in green tea leaves, (-)-epigallocatechin gallate (EGCG), L-theanine (theanine) and caffeine, were investigated for their...

Epigallocatechin gallate (EGCG) suppresses lipopolysaccharide-induced inflammatory bone resorption, and protects against alveolar bone loss in mice.

FEBS open bio

Tominari T, Matsumoto C, Watanabe K, Hirata M, Grundler FM, Miyaura C, Inada M.
PMID: 26155460
FEBS Open Bio. 2015 Jun 12;5:522-7. doi: 10.1016/j.fob.2015.06.003. eCollection 2015.

Epigallocatechin gallate (EGCG), a major polyphenol in green tea, possesses antioxidant properties and regulates various cell functions. Here, we examined the function of EGCG in inflammatory bone resorption. In calvarial organ cultures, lipopolysaccharide (LPS)-induced bone resorption was clearly suppressed...

Chronic treatment with epigallocatechin gallate reduces motor hyperactivity and affects in vitro tested intestinal motility of spontaneously hypertensive rats.

Food & nutrition research

Potenza MA, Montagnani M, Nacci C, De Salvia MA.
PMID: 26899572
Food Nutr Res. 2016 Feb 17;60:28373. doi: 10.3402/fnr.v60.28373. eCollection 2016.

BACKGROUND: Green tea catechins seem to contribute toward reducing body weight and fat.OBJECTIVE: We aimed to investigate whether chronic administration of (-)-epigallocatechin-3-gallate (EGCG), the most abundant catechin of green tea, reduces weight gain in spontaneously hypertensive rats (SHR), an...

Accumulation of catechins and expression of catechin synthetic genes in Camellia sinensis at different developmental stages.

Botanical studies

Zhang LQ, Wei K, Cheng H, Wang LY, Zhang CC.
PMID: 28597441
Bot Stud. 2016 Dec;57(1):31. doi: 10.1186/s40529-016-0143-9. Epub 2016 Oct 24.

BACKGROUND: Catechins are the main polyphenol compounds in tea (Camellia sinensis). To understand the relationship between gene expression and product accumulation, the levels of catechins and relative expressions of key genes in tea leaves of different developmental stages were...

In silico studies of medicinal compounds against hepatitis C capsid protein from north India.

Bioinformatics and biology insights

Mathew S, Faheem M, Archunan G, Ilyas M, Begum N, Jahangir S, Qadri I, Qahtani MA, Mathew S.
PMID: 25002815
Bioinform Biol Insights. 2014 Jun 23;8:159-68. doi: 10.4137/BBI.S15211. eCollection 2014.

Hepatitis viral infection is a leading cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma (HCC). Over one million people are estimated to be persistently infected with hepatitis C virus (HCV) worldwide. As capsid core protein is the key element...

Effects of alternative steeping methods on composition, antioxidant property and colour of green, black and oolong tea infusions.

Journal of food science and technology

Lantano C, Rinaldi M, Cavazza A, Barbanti D, Corradini C.
PMID: 26604404
J Food Sci Technol. 2015 Dec;52(12):8276-83. doi: 10.1007/s13197-015-1971-4. Epub 2015 Jul 29.

Cold water steeping is reported to maximise tea health benefits, but requires long infusion time. In this work, the employment of a brief hot infusion step followed by ice addition was evaluated. The comparison of this innovative method with...

The Effect of Epigallocatechin Gallate on the Dentin Bond Durability of Two Self-etch Adhesives.

Journal of dentistry (Shiraz, Iran)

Khamverdi Z, Rezaei-Soufi L, Rostamzadeh T.
PMID: 26046100
J Dent (Shiraz). 2015 Jun;16(2):68-74.

STATEMENT OF THE PROBLEM: Self-etch adhesives can activate matrix metalloproteinase (MMP) which hydrolyzes organic matrix of demineralized dentin. Epigallocatechin gallate (EGCG), especially found in green tea, could inhibit the activation of MMP.PURPOSE: The aim of this study was to...

Blood brain barrier permeability of (-)-epigallocatechin gallate, its proliferation-enhancing activity of human neuroblastoma SH-SY5Y cells, and its preventive effect on age-related cognitive dysfunction in mice.

Biochemistry and biophysics reports

Pervin M, Unno K, Nakagawa A, Takahashi Y, Iguchi K, Yamamoto H, Hoshino M, Hara A, Takagaki A, Nanjo F, Minami A, Imai S, Nakamura Y.
PMID: 28956003
Biochem Biophys Rep. 2017 Jan 05;9:180-186. doi: 10.1016/j.bbrep.2016.12.012. eCollection 2017 Mar.

BACKGROUND: The consumption of green tea catechins (GTCs) suppresses age-related cognitive dysfunction in mice. GTCs are composed of several catechins, of which epigallocatechin gallate (EGCG) is the most abundant, followed by epigallocatechin (EGC). Orally ingested EGCG is hydrolyzed by...

Simple isocratic method for simultaneous determination of caffeine and catechins in tea products by HPLC.

SpringerPlus

Fernando CD, Soysa P.
PMID: 27429880
Springerplus. 2016 Jul 04;5(1):970. doi: 10.1186/s40064-016-2672-9. eCollection 2016.

Tea is a popular beverage almost all over the world. Many studies show that tea consumption is closely associated with positive health impact. Most of the HPLC methods used for the determination of tea constituents include gradient elution systems...

Effects of tea polyphenols on proliferation and apoptosis of cadmium-transformed cells.

International journal of clinical and experimental medicine

Wang M, Lei YX.
PMID: 25932282
Int J Clin Exp Med. 2015 Feb 15;8(2):3054-62. eCollection 2015.

To investigate the roles and mechanism(s) of epigallocatechin gallate (EGCG) in carcinogenesis in malignant transformed cell line, cadmium-induced malignant transformed cells were treated with different doses of EGCG. Then cell proliferation, cell apoptosis, hTERT mRNA and protein level, and...

Epigallocatechin Gallate-Mediated Alteration of the MicroRNA Expression Profile in 5α-Dihydrotestosterone-Treated Human Dermal Papilla Cells.

Annals of dermatology

Shin S, Kim K, Lee MJ, Lee J, Choi S, Kim KS, Ko JM, Han H, Kim SY, Youn HJ, Ahn KJ, An IS, An S, Cha HJ.
PMID: 27274631
Ann Dermatol. 2016 Jun;28(3):327-34. doi: 10.5021/ad.2016.28.3.327. Epub 2016 May 25.

BACKGROUND: Dihydrotestosterone (DHT) induces androgenic alopecia by shortening the hair follicle growth phase, resulting in hair loss. We previously demonstrated how changes in the microRNA (miRNA) expression profile influenced DHT-mediated cell death, cell cycle arrest, cell viability, the generation...

Gateways to clinical trials. July-August 2008.

Methods and findings in experimental and clinical pharmacology

Tomillero A, Moral MA.
PMID: 18850047
Methods Find Exp Clin Pharmacol. 2008 Jul-Aug;30(6):459-95.

(-)-Epigallocatechin gallate, 501516, 89-12; Abatacept, Adalimumab, Adefovir dipivoxil, AG-701, Agatolimod sodium, Alefacept, Aliskiren fumarate, Apixaban, Atazanavir sulfate, Atrasentan, Axitinib; BI-1744-CL, BIBF-1120, BIBW-2992, Bortezomib; Carboxyamidotriazole, Caspofungin acetate, CBP-501, Cediranib, Ceftobiprole, Certolizumab pegol, Cetuximab, Cholesteryl hydrophobized polysaccharide-Her2 protein complex, CHP-NY-ESO-1, Cypher;...

Showing 1 to 12 of 492 entries