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Reducing Cytoplasmic Polyamine Oxidase Activity in Arabidopsis Increases Salt and Drought Tolerance by Reducing Reactive Oxygen Species Production and Increasing Defense Gene Expression.

Frontiers in plant science

Sagor GH, Zhang S, Kojima S, Simm S, Berberich T, Kusano T.
PMID: 26973665
Front Plant Sci. 2016 Feb 29;7:214. doi: 10.3389/fpls.2016.00214. eCollection 2016.

The link between polyamine oxidases (PAOs), which function in polyamine catabolism, and stress responses remains elusive. Here, we address this issue using Arabidopsis pao mutants in which the expression of the five PAO genes is knocked-out or knocked-down. As...

Mechanism of polyamine toxicity in cultured cardiac myocytes.

Toxicology in vitro : an international journal published in association with BIBRA

Tipnis UR, He GY.
PMID: 20654405
Toxicol In Vitro. 1998 Jun 01;12(3):233-40. doi: 10.1016/s0887-2333(97)00116-1.

The goal of this study was to investigate the mechanism of polyamine-mediated injury to the cardiac myocytes isolated from neonatal rat hearts. The myocytes, cultured in Dulbecco's minimal essential medium-1% foetal calf serum (FBS), were exposed to spermidine or...

Polyamine-Induced Rapid Root Abscission in Azolla pinnata.

Journal of amino acids

Gurung S, Cohen MF, Fukuto J, Yamasaki H.
PMID: 22997568
J Amino Acids. 2012;2012:493209. doi: 10.1155/2012/493209. Epub 2012 Sep 11.

Floating ferns of the genus Azolla detach their roots under stress conditions, a unique adaptive response termed rapid root abscission. We found that Azolla pinnata plants exhibited dose-dependent rapid root abscission in response to the polyamines spermidine and spermine...

Expression profile of seven polyamine oxidase genes in rice (.

Physiology and molecular biology of plants : an international journal of functional plant biology

Sagor GHM, Inoue M, Kusano T, Berberich T.
PMID: 34220045
Physiol Mol Biol Plants. 2021 Jun;27(6):1353-1359. doi: 10.1007/s12298-021-01006-1. Epub 2021 May 28.

Polyamine levels are controlled by biosynthesis, intra- and inter-cellular flux by the respective transporters, and catabolism. The catabolism is catalyzed by two groups of enzymes. One is copper-containing amine oxidases and the other is polyamine oxidases (PAOs). In SUPPLEMENTARY...

In vivo inhibition of polyamine oxidase by a spermine analogue, MDL-72527, in tomato exposed to sublethal and lethal salt stress.

Functional plant biology : FPB

Takács Z, Poór P, Szepesi Á, Tari I.
PMID: 32480581
Funct Plant Biol. 2017 May;44(5):480-492. doi: 10.1071/FP16280.

The spermine analogue N1,N4-bis-(2,3-butadienyl)-1,4-butanediamine (MDL-72527), an effective inhibitor of polyamine oxidases (PAOs), triggers a systemic response in tomato (Solanum lycopersicum L.) exposed to sublethal (100mM) and lethal (250mM) NaCl concentrations. The accumulation of free polyamines (PAs), the terminal oxidation...

Enhancing antioxidant systems by exogenous spermine and spermidine in wheat (Triticum aestivum) seedlings exposed to salt stress.

Functional plant biology : FPB

ElSayed AI, Rafudeen MS, El-Hamahmy MAM, Odero DC, Hossain MS.
PMID: 32291049
Funct Plant Biol. 2018 Jun;45(7):745-759. doi: 10.1071/FP17127.

Plants have evolved complex mechanisms to mitigate osmotic and ionic stress caused by high salinity. The effect of exogenous spermine (Spm) and spermidine (Spd) on defence responses of wheat seedlings under NaCl stress was investigated by measuring antioxidant enzyme...

Plant Polyamines.

Plants (Basel, Switzerland)

Takahashi T.
PMID: 32316095
Plants (Basel). 2020 Apr 16;9(4). doi: 10.3390/plants9040511.

Polyamines are small organic compounds found in all living organisms. According to the high degree of positive charge at physiological pH, they interact with negatively charged macromolecules, such as DNA, RNA, and proteins, and modulate their activities. In plants,...

A rapid and sensitive assay method for measuring amine oxidase based on hydrogen peroxide-titanium complex formation.

Plant science : an international journal of experimental plant biology

Nag S, Saha K, Choudhuri MA.
PMID: 10960728
Plant Sci. 2000 Aug 22;157(2):157-163. doi: 10.1016/s0168-9452(00)00281-8.

Hydrogenperoxide (H(2)O(2)) is an end product of diamine and polyamine oxidation by their respective oxidase enzymes. A new sensitive assay method is based on a H(2)O(2)-titanium (Ti) complex formation as an indicator of H(2)O(2) production due to polyamine oxidation....

Cell Wall Amine Oxidases: New Players in Root Xylem Differentiation under Stress Conditions.

Plants (Basel, Switzerland)

Ghuge SA, Tisi A, Carucci A, Rodrigues-Pousada RA, Franchi S, Tavladoraki P, Angelini R, Cona A.
PMID: 27135338
Plants (Basel). 2015 Jul 14;4(3):489-504. doi: 10.3390/plants4030489.

Polyamines (PAs) are aliphatic polycations present in all living organisms. A growing body of evidence reveals their involvement as regulators in a variety of physiological and pathological events. They are oxidatively deaminated by amine oxidases (AOs), including copper amine...

Global Metabolic Profiling of Arabidopsis Polyamine Oxidase 4 (AtPAO4) Loss-of-Function Mutants Exhibiting Delayed Dark-Induced Senescence.

Frontiers in plant science

Sequera-Mutiozabal MI, Erban A, Kopka J, Atanasov KE, Bastida J, Fotopoulos V, Alcázar R, Tiburcio AF.
PMID: 26925084
Front Plant Sci. 2016 Feb 18;7:173. doi: 10.3389/fpls.2016.00173. eCollection 2016.

Early and more recent studies have suggested that some polyamines (PAs), and particularly spermine (Spm), exhibit anti-senescence properties in plants. In this work, we have investigated the role of Arabidopsis Polyamine Oxidase 4 (PAO4), encoding a PA back-conversion oxidase,...

Peroxisomal polyamine oxidase and NADPH-oxidase cross-talk for ROS homeostasis which affects respiration rate in Arabidopsis thaliana.

Frontiers in plant science

Andronis EA, Moschou PN, Toumi I, Roubelakis-Angelakis KA.
PMID: 24765099
Front Plant Sci. 2014 Apr 03;5:132. doi: 10.3389/fpls.2014.00132. eCollection 2014.

Homeostasis of reactive oxygen species (ROS) in the intracellular compartments is of critical importance as ROS have been linked with nearly all cellular processes and more importantly with diseases and aging. PAs are nitrogenous molecules with an evolutionary conserved...

Genome-Wide Identification of Seven Polyamine Oxidase Genes in .

Frontiers in plant science

Li M, Lu J, Tao M, Li M, Yang H, Xia EH, Chen Q, Wan X.
PMID: 33013966
Front Plant Sci. 2020 Sep 04;11:544933. doi: 10.3389/fpls.2020.544933. eCollection 2020.

Polyamines (PAs) in plant play a critical role in growth and development and in response to environmental stress. Polyamine oxidase (PAO) is a flavin adenine dinucleotide dependent enzyme that plays a major role in PA catabolism. For the first...

Showing 1 to 12 of 57 entries