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Showing 1 to 12 of 44 entries
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Advances in Improving Healthcare with Aggregation-Induced Emission.

Advanced healthcare materials

Ding D, Tang BZ.
PMID: 34935308
Adv Healthc Mater. 2021 Dec;10(24):e2102499. doi: 10.1002/adhm.202102499.

No abstract available.

Characterization of the fluorescence emission properties of prodan in different reverse micellar environments.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Sengupta B, Guharay J, Sengupta PK.
PMID: 10888447
Spectrochim Acta A Mol Biomol Spectrosc. 2000 Jun;56(7):1433-41. doi: 10.1016/s1386-1425(00)00245-6.

We have examined the steady state and time resolved fluorescence emission properties of the hydrophobic fluorescence probe, prodan, in three representative reverse micellar systems formed by the surfactants poly(oxyethylene) (tetramethylbutyl) phenylether (Triton X-100, neutral), cetyl trimethylammonium bromide (CTAB, cationic)...

Coordinating Self-Assembly of Copper Perylenetetracarboxylate Nanorods: Selectively Lighting up Normal Cells around Cancerous Ones for Better Cancer Diagnosis.

ACS applied materials & interfaces

Wang L, Gao X, Wei Y, Liu K, Huang J, Wang J, Yan Y.
PMID: 29733187
ACS Appl Mater Interfaces. 2018 May 30;10(21):17630-17638. doi: 10.1021/acsami.8b03211. Epub 2018 May 16.

Specific imaging of cancer cells has been well-accepted in cancer diagnosis although it cannot precisely mark the boundary between the normal and cancerous cells and report their mutual influence. We report a nanorod fluorescent probe of copper perylenetetracarbonate (PTC-Cu)...

Electrokinetic molecular separation in nanoscale fluidic channels.

Lab on a chip

Garcia AL, Ista LK, Petsev DN, O'Brien MJ, Bisong P, Mammoli AA, Brueck SR, López GP.
PMID: 16234951
Lab Chip. 2005 Nov;5(11):1271-6. doi: 10.1039/b503914b. Epub 2005 Sep 12.

This report presents a study of electrokinetic transport in a series of integrated macro- to nano-fluidic chips that allow for controlled injection of molecular mixtures into high-density arrays of nanochannels. The high-aspect-ratio nanochannels were fabricated on a Si wafer...

Image-Guided Tumor Resection.

Cancer journal (Sudbury, Mass.)

Parrish-Novak J, Holland EC, Olson JM.
PMID: 26049700
Cancer J. 2015 May-Jun;21(3):206-12. doi: 10.1097/PPO.0000000000000113.

Each year, millions of individuals undergo cancer surgery that is intended to be curative or at least a necessary component of a curative regimen. Particularly for those patients whose cancer harbors cells that are resistant to chemotherapy or radiation,...

A geometric-sensitivity-difference method improves object depth-localization for continuous-wave fluorescence diffuse optical tomography: an in silico study in an axial outward-imaging geometry.

Journal of X-ray science and technology

Tokala KT, Piao D, Xu G, Ertmer PA, Ottenbreit-Leftwich AT, Sadik O.
PMID: 25265923
J Xray Sci Technol. 2014;22(5):627-43. doi: 10.3233/XST-140450.

A geometric-sensitivity-difference (GSD) based reconstruction method is demonstrated in fluorescence diffuse optical tomography (FDOT) for improving the depth-localization of objects. The GSD method optimizes the data-model fit based on paired-measurements between source-detector pairs sharing either the source or the...

Smart dual-mode fluorescent gold nanoparticle agents.

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology

Kang KA, Wang J.
PMID: 24715524
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2014 Jul-Aug;6(4):398-409. doi: 10.1002/wnan.1267. Epub 2014 Apr 08.

UNLABELLED: Fluorophore-mediated, molecular sensing is one of the most popular and important technique in biomedical studies. As in any sensing technique, the two most important factors in this sensing are the sensitivity and specificity. Since the fluorescence of a...

Testing the use of molecular dynamics to simulate fluorophore motions and FRET.

Physical chemistry chemical physics : PCCP

Deplazes E, Jayatilaka D, Corry B.
PMID: 21556410
Phys Chem Chem Phys. 2011 Jun 21;13(23):11045-54. doi: 10.1039/c1cp20447e. Epub 2011 May 09.

Fluorescence resonance energy transfer (FRET) is commonly used to determine the proximity of fluorophores, but usually many assumptions are required to gain a quantitative relationship between the likelihood of energy transfer and fluorophore separation. Molecular Dynamics (MD) simulations provide...

Aggregation-Induced Emission-Active Near-Infrared Fluorescent Organic Nanoparticles for Noninvasive Long-Term Monitoring of Tumor Growth.

ACS applied materials & interfaces

Xia Q, Chen Z, Yu Z, Wang L, Qu J, Liu R.
PMID: 29717866
ACS Appl Mater Interfaces. 2018 May 23;10(20):17081-17088. doi: 10.1021/acsami.8b03861. Epub 2018 May 10.

Effective long-term monitoring of tumor growth is significant for the evaluation of cancer therapy. Aggregation-induced emission-active near-infrared (NIR) fluorescent organic nanoparticles (TPFE-Rho dots) are designed and synthesized for long-term in vitro cell tracking and in vivo monitoring of tumor...

Fluorescent aptasensors for parallel analysis of biomolecules based on interlocked DNA catenane nanomachines.

Analytica chimica acta

Liao H, Huang T, Hu L, Wang M.
PMID: 32359510
Anal Chim Acta. 2020 Jun 01;1114:1-6. doi: 10.1016/j.aca.2020.04.004. Epub 2020 Apr 06.

Stimuli-responsive DNA catenane nanomachines have received considerable interest in the area of DNA nanotechnology. However, the sensing and bio-sensing applications of DNA catenane nanomachines are rarely explored. Herein, the biological small molecule and protein responsive DNA catenane nanomachines were...

A Spiral-Helix (3D) Tubing Array That Ensures Ultrahigh-Throughput Single-Cell Sampling.

Analytical chemistry

Wei X, Zhang X, Guo R, Chen ML, Yang T, Xu ZR, Wang JH.
PMID: 31724393
Anal Chem. 2019 Dec 17;91(24):15826-15832. doi: 10.1021/acs.analchem.9b04122. Epub 2019 Nov 25.

ICP-MS is powerful in evaluating elemental species at the single-cell level, where high throughput/efficiency/precision are the keys for achieving statistically significant information based on massive data. We report an ultrahigh-throughput single-cell sampling system, consisting of a 3D spiral-helix tubing...

Tuning the Brightness and Photostability of Organic Dots for Multivalent Targeted Cancer Imaging and Surgery.

ACS nano

Cong H, Wang K, Zhou Z, Yang J, Piao Y, Yu B, Shen Y, Zhou Z.
PMID: 32356972
ACS Nano. 2020 May 26;14(5):5887-5900. doi: 10.1021/acsnano.0c01034. Epub 2020 May 07.

Specific labeling of biomarkers with bright and high photostable fluorophores is vital in fluorescent imaging applications. Here, we report a general strategy to develop single-molecule dendritic nanodots with finely tunable optical properties for

Showing 1 to 12 of 44 entries