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Showing 1 to 12 of 25 entries
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Characterization of the fluorescence emission properties of prodan in different reverse micellar environments.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Sengupta B, Guharay J, Sengupta PK.
PMID: 10888447
Spectrochim Acta A Mol Biomol Spectrosc. 2000 Jun;56(7):1433-41. doi: 10.1016/s1386-1425(00)00245-6.

We have examined the steady state and time resolved fluorescence emission properties of the hydrophobic fluorescence probe, prodan, in three representative reverse micellar systems formed by the surfactants poly(oxyethylene) (tetramethylbutyl) phenylether (Triton X-100, neutral), cetyl trimethylammonium bromide (CTAB, cationic)...

A geometric-sensitivity-difference method improves object depth-localization for continuous-wave fluorescence diffuse optical tomography: an in silico study in an axial outward-imaging geometry.

Journal of X-ray science and technology

Tokala KT, Piao D, Xu G, Ertmer PA, Ottenbreit-Leftwich AT, Sadik O.
PMID: 25265923
J Xray Sci Technol. 2014;22(5):627-43. doi: 10.3233/XST-140450.

A geometric-sensitivity-difference (GSD) based reconstruction method is demonstrated in fluorescence diffuse optical tomography (FDOT) for improving the depth-localization of objects. The GSD method optimizes the data-model fit based on paired-measurements between source-detector pairs sharing either the source or the...

Smart dual-mode fluorescent gold nanoparticle agents.

Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology

Kang KA, Wang J.
PMID: 24715524
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2014 Jul-Aug;6(4):398-409. doi: 10.1002/wnan.1267. Epub 2014 Apr 08.

UNLABELLED: Fluorophore-mediated, molecular sensing is one of the most popular and important technique in biomedical studies. As in any sensing technique, the two most important factors in this sensing are the sensitivity and specificity. Since the fluorescence of a...

Testing the use of molecular dynamics to simulate fluorophore motions and FRET.

Physical chemistry chemical physics : PCCP

Deplazes E, Jayatilaka D, Corry B.
PMID: 21556410
Phys Chem Chem Phys. 2011 Jun 21;13(23):11045-54. doi: 10.1039/c1cp20447e. Epub 2011 May 09.

Fluorescence resonance energy transfer (FRET) is commonly used to determine the proximity of fluorophores, but usually many assumptions are required to gain a quantitative relationship between the likelihood of energy transfer and fluorophore separation. Molecular Dynamics (MD) simulations provide...

Fluorescent aptasensors for parallel analysis of biomolecules based on interlocked DNA catenane nanomachines.

Analytica chimica acta

Liao H, Huang T, Hu L, Wang M.
PMID: 32359510
Anal Chim Acta. 2020 Jun 01;1114:1-6. doi: 10.1016/j.aca.2020.04.004. Epub 2020 Apr 06.

Stimuli-responsive DNA catenane nanomachines have received considerable interest in the area of DNA nanotechnology. However, the sensing and bio-sensing applications of DNA catenane nanomachines are rarely explored. Herein, the biological small molecule and protein responsive DNA catenane nanomachines were...

A Spiral-Helix (3D) Tubing Array That Ensures Ultrahigh-Throughput Single-Cell Sampling.

Analytical chemistry

Wei X, Zhang X, Guo R, Chen ML, Yang T, Xu ZR, Wang JH.
PMID: 31724393
Anal Chem. 2019 Dec 17;91(24):15826-15832. doi: 10.1021/acs.analchem.9b04122. Epub 2019 Nov 25.

ICP-MS is powerful in evaluating elemental species at the single-cell level, where high throughput/efficiency/precision are the keys for achieving statistically significant information based on massive data. We report an ultrahigh-throughput single-cell sampling system, consisting of a 3D spiral-helix tubing...

Devising Efficient Red-Shifting Strategies for Bioimaging: A Generalizable Donor-Acceptor Fluorophore Prototype.

Chemistry, an Asian journal

Chen C, Fang C.
PMID: 32216076
Chem Asian J. 2020 May 15;15(10):1514-1523. doi: 10.1002/asia.202000175. Epub 2020 Apr 08.

Long emission wavelengths, high fluorescence quantum yields (FQYs), and large Stokes shifts are highly desirable features for fluorescent probes in biological imaging. However, the current development of many fluorescent probes remains largely trial-and-error and lacks efficiency. Moreover, to achieve...

Distance Dependence of Single-Molecule Energy Transfer to Graphene Measured with DNA Origami Nanopositioners.

Nano letters

Kaminska I, Bohlen J, Rocchetti S, Selbach F, Acuna GP, Tinnefeld P.
PMID: 31251640
Nano Lett. 2019 Jul 10;19(7):4257-4262. doi: 10.1021/acs.nanolett.9b00172. Epub 2019 Jun 28.

Despite the thorough investigation of graphene since 2004, altering its surface chemistry and reproducible functionalization remain challenging. This hinders fabrication of more complex hybrid materials with controlled architectures, and as a consequence the development of sensitive and reliable sensors...

Analysis of protein changes using two-dimensional difference gel electrophoresis.

Methods in molecular biology (Clifton, N.J.)

Gao W.
PMID: 24623216
Methods Mol Biol. 2014;1105:17-30. doi: 10.1007/978-1-62703-739-6_2.

A protocol for protein analysis using two-dimensional difference gel electrophoresis (2D-DIGE) is described. 2D-DIGE is one of the most popular and versatile methods of protein separation among rapidly increasing proteomics technologies. Similar to traditional two-dimensional polyacrylamide gel electrophoresis (2D-PAGE),...

Synthesis, crystals of centrosymmetric triphenylamine chromophores bearing prodigious two-photon absorption cross-section and biological imaging.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Wang S, Xu S, Wang Y, Tian X, Zhang Y, Wang C, Wu J, Yang J, Tian Y.
PMID: 27816887
Spectrochim Acta A Mol Biomol Spectrosc. 2017 Feb 15;173:871-879. doi: 10.1016/j.saa.2016.10.059. Epub 2016 Oct 31.

Two centrosymmetric D-π-D type triphenylamine chromophores with long π-conjugated bridge and strong electron-donating moiety were designed, synthesized and fully characterized. The crystal analysis revealed that multiple CH⋯π interactions existed in two chromophores, which played a crucial role in generating...

Quencher-free fluorescent method for homogeneously sensitive detection of microRNAs in human lung tissues.

Analytical chemistry

Zhu G, Liang L, Zhang CY.
PMID: 25356523
Anal Chem. 2014 Nov 18;86(22):11410-6. doi: 10.1021/ac503365z. Epub 2014 Nov 07.

Sensitive and accurate analysis of microRNA (miRNA) expression is imperative for understanding the biological functions of miRNAs and the early diagnosis of human cancers. Here, we develop a quencher-free fluorescent method for homogeneously sensitive detection of let-7a miRNA using...

The Promise of Aggregation-Induced Emission Luminogens for Detecting COVID-19.

Frontiers in immunology

Liu Z, Meng T, Tang X, Tian R, Guan W.
PMID: 33679789
Front Immunol. 2021 Feb 16;12:635558. doi: 10.3389/fimmu.2021.635558. eCollection 2021.

The long-term pandemic of coronavirus disease 2019 (COVID-19) requires sensitive and accurate diagnostic assays to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus and SARS-CoV-2 antibodies in infected individuals. Currently, RNA of SARS-CoV-2 virus is mainly detected by...

Showing 1 to 12 of 25 entries