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Li W, Quan Y, Zhang M, et al. Effects of pituitary-specific overexpression of FSHα/β on reproductive traits in transgenic boars. J Anim Sci Biotechnol. 2017;8:84doi: 10.1186/s40104-017-0208-y.
Li, W., Quan, Y., Zhang, M., Wang, K., Zhu, M., Chen, Y., Li, Q., & Wu, K. (2017). Effects of pituitary-specific overexpression of FSHα/β on reproductive traits in transgenic boars. Journal of animal science and biotechnology, 884. https://doi.org/10.1186/s40104-017-0208-y
Li, Wenting, et al. "Effects of pituitary-specific overexpression of FSHα/β on reproductive traits in transgenic boars." Journal of animal science and biotechnology vol. 8 (2017): 84. doi: https://doi.org/10.1186/s40104-017-0208-y
Li W, Quan Y, Zhang M, Wang K, Zhu M, Chen Y, Li Q, Wu K. Effects of pituitary-specific overexpression of FSHα/β on reproductive traits in transgenic boars. J Anim Sci Biotechnol. 2017 Oct 25;8:84. doi: 10.1186/s40104-017-0208-y. eCollection 2017. PMID: 29090093; PMCID: PMC5655851.
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J Anim Sci Biotechnol. 2017 Oct 25;8:84. doi: 10.1186/s40104-017-0208-y. eCollection 2017.

Effects of pituitary-specific overexpression of FSHα/β on reproductive traits in transgenic boars.

Journal of animal science and biotechnology

Wenting Li, Yujun Quan, Mengmeng Zhang, Kejun Wang, Muzhen Zhu, Ye Chen, Qiuyan Li, Keliang Wu

Affiliations

  1. College of Animal Science and Technology, China Agricultural University, Beijing, 100193 China.
  2. College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450002 China.
  3. Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101 China.
  4. The Department of Animal Husbandry, Rongchang Campus, Southwest University, Rongchang, Chongqing, 402460 China.
  5. State Key Laboratory for Agrobiotechnology, China Agricultural University, Beijing, 100193 China.

PMID: 29090093 PMCID: PMC5655851 DOI: 10.1186/s40104-017-0208-y

Abstract

BACKGROUND: Follicle-stimulating hormone (FSH) is a gonadotropin synthesized and secreted by the pituitary gland. FSH stimulates follicle development and maturation in females. It also plays an important role in spermatogenesis in males, including humans and mice. However, the effects of FSH on male pigs are largely unknown. In this study, we generated transgenic pigs to investigate the effects of FSHα/β overexpression on reproductive traits in boars.

RESULTS: After five transgenic F

CONCLUSIONS: Pituitary-specific overexpression of

Keywords: Boar; FSHα/β; Reproductive traits; Transgene

References

  1. Mol Endocrinol. 1992 Jan;6(1):81-90 - PubMed
  2. Horm Behav. 1977 Jun;8(3):275-86 - PubMed
  3. Recent Prog Horm Res. 1996;51:123-54; discussion 155-7 - PubMed
  4. World J Urol. 1997;15(1):21-6 - PubMed
  5. Fertil Steril. 1976 Mar;27(3):271-4 - PubMed
  6. J Endocrinol. 2010 May;205(2):117-31 - PubMed
  7. Endocr Rev. 1990 Feb;11(1):177-99 - PubMed
  8. Anim Genet. 2015 Feb;46(1):16-22 - PubMed
  9. PLoS One. 2012;7(4):e35136 - PubMed
  10. J Clin Endocrinol Metab. 2006 Jul;91(7):2509-13 - PubMed
  11. Trop Anim Health Prod. 2007 May;39(4):271-7 - PubMed
  12. Nucleic Acids Res. 2013 Jan;41(Database issue):D871-9 - PubMed
  13. Sci China C Life Sci. 2004 Apr;47(2):183-9 - PubMed
  14. Mol Endocrinol. 1993 Jul;7(7):898-906 - PubMed
  15. Nat Genet. 1997 Feb;15(2):201-4 - PubMed
  16. Mol Cell Endocrinol. 1989 Mar;62(1):135-9 - PubMed
  17. Proc Natl Acad Sci U S A. 1996 Jan 9;93(1):201-5 - PubMed
  18. Annu Rev Biochem. 1981;50:465-95 - PubMed
  19. Mol Cell Endocrinol. 2007 Jan 2;260-262:249-54 - PubMed
  20. Sci China C Life Sci. 1998 Dec;41(6):664-8 - PubMed
  21. Anim Reprod Sci. 2009 Feb;110(3-4):269-82 - PubMed
  22. Endocr Rev. 2000 Apr;21(2):200-14 - PubMed
  23. PLoS One. 2012;7(7):e42335 - PubMed

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