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Gkouskou K, Lazou E, Skoufas E, et al. Genetically Guided Mediterranean Diet for the Personalized Nutritional Management of Type 2 Diabetes Mellitus. Nutrients. 2021;13(2)doi: 10.3390/nu13020355.
Gkouskou, K., Lazou, E., Skoufas, E., & Eliopoulos, A. G. (2021). Genetically Guided Mediterranean Diet for the Personalized Nutritional Management of Type 2 Diabetes Mellitus. Nutrients, 13(2), . https://doi.org/10.3390/nu13020355
Gkouskou, Kalliopi, et al. "Genetically Guided Mediterranean Diet for the Personalized Nutritional Management of Type 2 Diabetes Mellitus." Nutrients vol. 13,2 (2021). doi: https://doi.org/10.3390/nu13020355
Gkouskou K, Lazou E, Skoufas E, Eliopoulos AG. Genetically Guided Mediterranean Diet for the Personalized Nutritional Management of Type 2 Diabetes Mellitus. Nutrients. 2021 Jan 25;13(2). doi: 10.3390/nu13020355. PMID: 33503923; PMCID: PMC7912380.
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Nutrients. 2021 Jan 25;13(2). doi: 10.3390/nu13020355.

Genetically Guided Mediterranean Diet for the Personalized Nutritional Management of Type 2 Diabetes Mellitus.

Nutrients

Kalliopi Gkouskou, Evgenia Lazou, Efstathios Skoufas, Aristides G Eliopoulos

Affiliations

  1. Department of Biology, School of Medicine, National and Kapodistrian University of Athens, Mikras Asias 75, 11527 Athens, Greece.
  2. Embiodiagnostics Biology Research Company, 71305 Heraklion, Greece.
  3. Center for New Biotechnologies and Precision Medicine, School of Medicine, National and Kapodistrian University of Athens, 15772 Athens, Greece.
  4. Center of Basic Research, Biomedical Research Foundation of the Academy of Athens, 11527 Athens, Greece.

PMID: 33503923 PMCID: PMC7912380 DOI: 10.3390/nu13020355

Abstract

The current consensus for the prevention and management of type 2 diabetes mellitus (T2DM) is that high-quality diets and adherence to a healthy lifestyle provide significant health benefits. Remarkably, however, there is little agreement on the proportions of macronutrients in the diet that should be recommended to people suffering from pre-diabetes or T2DM. We herein discuss emerging evidence that underscores the importance of gene-diet interactions in the improvement of glycemic biomarkers in T2DM. We propose that we can achieve better glycemic control in T2DM patients by coupling Mediterranean diets to genetic information as a predictor for optimal diet macronutrient composition in a personalized manner. We provide evidence to support this concept by presenting a case study of a T2DM patient who achieved rapid glycemic control when adhered to a personalized, genetically-guided Mediterranean Diet.

Keywords: Mediterranean diet; SNP; glycemia; nutrigenetics; personalized nutrition; type 2 diabetes mellitus

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