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Emerging empirical science of wisdom: definition, measurement, neurobiology, longevity, and interventions

Science interventions

Lee EE.
GSID: IaLH3ST0qsMJ
DV Jeste, EE Lee - Harvard review of psychiatry, 2019 - ncbi.nlm.nih.gov

Wisdom has been discussed for centuries in religious and philosophical texts. However, since the 1970s the field of empirical research on wisdom has been growing, similar to scientific inquires into other seemingly fuzzy psychological constructs such as consciousness, stress,...

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Jeste, D. V., & Lee, E. E. (2019). Emerging empirical science of wisdom: definition, measurement, neurobiology, longevity, and interventions. Harvard review of psychiatry, 27(3), 127.
Jeste, Dilip V., and Ellen E. Lee. "Emerging empirical science of wisdom: definition, measurement, neurobiology, longevity, and interventions." Harvard review of psychiatry 27.3 (2019): 127.
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Editorial: Is our value beyond measure?.

Journal of medical education

Lee E.
PMID: 957397
J Med Educ. 1976 Sep;51(9):776-8.

No abstract available.

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Lee E. Editorial: Is our value beyond measure?. J Med Educ. 1976;51(9):776-8
Lee, E. (1976). Editorial: Is our value beyond measure?. Journal of medical education, 51(9), 776-8.
Lee, E. "Editorial: Is our value beyond measure?." Journal of medical education vol. 51,9 (1976): 776-8.
Lee E. Editorial: Is our value beyond measure?. J Med Educ. 1976 Sep;51(9):776-8. PMID: 957397.
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Carrier envelope offset frequency of a doubly resonant, nondegenerate, mid-infrared GaAs optical parametric oscillator.

Optics letters

Lee KF, Jiang J, Mohr C, Bethge J, Fermann ME, Leindecker N, Vodopyanov KL, Schunemann PG, Hartl I.
PMID: 23595427
Opt Lett. 2013 Apr 15;38(8):1191-3. doi: 10.1364/OL.38.001191.

We measure the carrier envelope offset (CEO) frequency of the mid-infrared frequency comb (wavelength tunable between 3 and 6 μm) from a doubly resonant nondegenerate synchronously pumped optical parametric oscillator (SPOPO) as a function of the CEO frequency of...

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Lee KF, Jiang J, Mohr C, et al. Carrier envelope offset frequency of a doubly resonant, nondegenerate, mid-infrared GaAs optical parametric oscillator. Opt Lett. 2013;38(8):1191-3doi: 10.1364/OL.38.001191.
Lee, K. F., Jiang, J., Mohr, C., Bethge, J., Fermann, M. E., Leindecker, N., Vodopyanov, K. L., Schunemann, P. G., & Hartl, I. (2013). Carrier envelope offset frequency of a doubly resonant, nondegenerate, mid-infrared GaAs optical parametric oscillator. Optics letters, 38(8), 1191-3. https://doi.org/10.1364/OL.38.001191
Lee, Kevin F, et al. "Carrier envelope offset frequency of a doubly resonant, nondegenerate, mid-infrared GaAs optical parametric oscillator." Optics letters vol. 38,8 (2013): 1191-3. doi: https://doi.org/10.1364/OL.38.001191
Lee KF, Jiang J, Mohr C, Bethge J, Fermann ME, Leindecker N, Vodopyanov KL, Schunemann PG, Hartl I. Carrier envelope offset frequency of a doubly resonant, nondegenerate, mid-infrared GaAs optical parametric oscillator. Opt Lett. 2013 Apr 15;38(8):1191-3. doi: 10.1364/OL.38.001191. PMID: 23595427.
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Nasopharyngeal Carriage Rate and Serotypes of Streptococcus pneumoniae and Antimicrobial Susceptibility in Healthy Korean Children Younger than 5 Years Old: Focus on Influence of Pneumococcal Conjugate Vaccination.

Infection & chemotherapy

Lee EK, Jun JK, Choi UY, Kwon HJ, Kim KH, Kang JH.
PMID: 24265953
Infect Chemother. 2013 Mar;45(1):76-84. doi: 10.3947/ic.2013.45.1.76. Epub 2013 Mar 29.

BACKGROUND: Even after pneumococcal vaccination introduction, Streptococcus pneumoniae (pneumoccocus) is still an important cause of respiratory and invasive severe infection. Pneumococcus is resided in nasal mucosa and local or systemic infection begins with the nasal mucosa damage. We studied...

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Lee EK, Jun JK, Choi UY, et al. Nasopharyngeal Carriage Rate and Serotypes of Streptococcus pneumoniae and Antimicrobial Susceptibility in Healthy Korean Children Younger than 5 Years Old: Focus on Influence of Pneumococcal Conjugate Vaccination. Infect Chemother. 2013;45(1):76-84doi: 10.3947/ic.2013.45.1.76.
Lee, E. K., Jun, J. K., Choi, U. Y., Kwon, H. J., Kim, K. H., & Kang, J. H. (2013). Nasopharyngeal Carriage Rate and Serotypes of Streptococcus pneumoniae and Antimicrobial Susceptibility in Healthy Korean Children Younger than 5 Years Old: Focus on Influence of Pneumococcal Conjugate Vaccination. Infection & chemotherapy, 45(1), 76-84. https://doi.org/10.3947/ic.2013.45.1.76
Lee, Eu Kyoung, et al. "Nasopharyngeal Carriage Rate and Serotypes of Streptococcus pneumoniae and Antimicrobial Susceptibility in Healthy Korean Children Younger than 5 Years Old: Focus on Influence of Pneumococcal Conjugate Vaccination." Infection & chemotherapy vol. 45,1 (2013): 76-84. doi: https://doi.org/10.3947/ic.2013.45.1.76
Lee EK, Jun JK, Choi UY, Kwon HJ, Kim KH, Kang JH. Nasopharyngeal Carriage Rate and Serotypes of Streptococcus pneumoniae and Antimicrobial Susceptibility in Healthy Korean Children Younger than 5 Years Old: Focus on Influence of Pneumococcal Conjugate Vaccination. Infect Chemother. 2013 Mar;45(1):76-84. doi: 10.3947/ic.2013.45.1.76. Epub 2013 Mar 29. PMID: 24265953; PMCID: PMC3780942.
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Temperature-dependent studies on the total phenolics, flavonoids, antioxidant activities, and sugar content in six onion varieties.

Journal of food and drug analysis

Sharma K, Ko EY, Assefa AD, Ha S, Nile SH, Lee ET, Park SW.
PMID: 28911379
J Food Drug Anal. 2015 Jun;23(2):243-252. doi: 10.1016/j.jfda.2014.10.005. Epub 2014 Dec 27.

Heating effect on total phenol, flavonoids, antioxidant activity, and sugar content of six onion varieties has been quantitatively investigated to explore the effect of different temperatures. The onion varieties comprised one red-skinned variety, two white-skinned varieties, and three yellow-skinned...

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Sharma K, Ko EY, Assefa AD, et al. Temperature-dependent studies on the total phenolics, flavonoids, antioxidant activities, and sugar content in six onion varieties. J Food Drug Anal. 2014;23(2):243-252doi: 10.1016/j.jfda.2014.10.005.
Sharma, K., Ko, E. Y., Assefa, A. D., Ha, S., Nile, S. H., Lee, E. T., & Park, S. W. (2015). Temperature-dependent studies on the total phenolics, flavonoids, antioxidant activities, and sugar content in six onion varieties. Journal of food and drug analysis, 23(2), 243-252. https://doi.org/10.1016/j.jfda.2014.10.005
Sharma, Kavita, et al. "Temperature-dependent studies on the total phenolics, flavonoids, antioxidant activities, and sugar content in six onion varieties." Journal of food and drug analysis vol. 23,2 (2015): 243-252. doi: https://doi.org/10.1016/j.jfda.2014.10.005
Sharma K, Ko EY, Assefa AD, Ha S, Nile SH, Lee ET, Park SW. Temperature-dependent studies on the total phenolics, flavonoids, antioxidant activities, and sugar content in six onion varieties. J Food Drug Anal. 2015 Jun;23(2):243-252. doi: 10.1016/j.jfda.2014.10.005. Epub 2014 Dec 27. PMID: 28911379.
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Biocompatibility and resorption pattern of newly developed hyaluronic acid hydrogel reinforced three-layer poly (lactide-co-glycolide) membrane: histologic observation in rabbit calvarial defect model.

Biomaterials research

You H, Lee EU, Kim YK, Kim BC, Park JY, Lim HC, Lee JS, Noh I, Jung UW, Choi SH.
PMID: 26331063
Biomater Res. 2014 Sep 24;18:12. doi: 10.1186/2055-7124-18-12. eCollection 2014.

BACKGROUND: The aim of this study was to evaluate the biocompatibility and resorption pattern in three-layer poly (lactide-co-glycolide) (PLGA) membrane according to the concentrations of hyaluronic acid (HA) hydrogel in rabbit calvarial defect model. Four standardized circular defects with...

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You H, Lee EU, Kim YK, et al. Biocompatibility and resorption pattern of newly developed hyaluronic acid hydrogel reinforced three-layer poly (lactide-co-glycolide) membrane: histologic observation in rabbit calvarial defect model. Biomater Res. 2014;18:12doi: 10.1186/2055-7124-18-12.
You, H., Lee, E. U., Kim, Y. K., Kim, B. C., Park, J. Y., Lim, H. C., Lee, J. S., Noh, I., Jung, U. W., & Choi, S. H. (2014). Biocompatibility and resorption pattern of newly developed hyaluronic acid hydrogel reinforced three-layer poly (lactide-co-glycolide) membrane: histologic observation in rabbit calvarial defect model. Biomaterials research, 1812. https://doi.org/10.1186/2055-7124-18-12
You, Hoon, et al. "Biocompatibility and resorption pattern of newly developed hyaluronic acid hydrogel reinforced three-layer poly (lactide-co-glycolide) membrane: histologic observation in rabbit calvarial defect model." Biomaterials research vol. 18 (2014): 12. doi: https://doi.org/10.1186/2055-7124-18-12
You H, Lee EU, Kim YK, Kim BC, Park JY, Lim HC, Lee JS, Noh I, Jung UW, Choi SH. Biocompatibility and resorption pattern of newly developed hyaluronic acid hydrogel reinforced three-layer poly (lactide-co-glycolide) membrane: histologic observation in rabbit calvarial defect model. Biomater Res. 2014 Sep 24;18:12. doi: 10.1186/2055-7124-18-12. eCollection 2014. PMID: 26331063; PMCID: PMC4552410.
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Inhibitory effect of burdock leaves on elastase and tyrosinase activity.

Experimental and therapeutic medicine

Horng CT, Wu HC, Chiang NN, Lee CF, Huang YS, Wang HY, Yang JS, Chen FA.
PMID: 28912875
Exp Ther Med. 2017 Oct;14(4):3247-3252. doi: 10.3892/etm.2017.4880. Epub 2017 Aug 03.

Burdock (

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Horng CT, Wu HC, Chiang NN, et al. Inhibitory effect of burdock leaves on elastase and tyrosinase activity. Exp Ther Med. 2017;14(4):3247-3252doi: 10.3892/etm.2017.4880.
Horng, C. T., Wu, H. C., Chiang, N. N., Lee, C. F., Huang, Y. S., Wang, H. Y., Yang, J. S., & Chen, F. A. (2017). Inhibitory effect of burdock leaves on elastase and tyrosinase activity. Experimental and therapeutic medicine, 14(4), 3247-3252. https://doi.org/10.3892/etm.2017.4880
Horng, Chi-Ting, et al. "Inhibitory effect of burdock leaves on elastase and tyrosinase activity." Experimental and therapeutic medicine vol. 14,4 (2017): 3247-3252. doi: https://doi.org/10.3892/etm.2017.4880
Horng CT, Wu HC, Chiang NN, Lee CF, Huang YS, Wang HY, Yang JS, Chen FA. Inhibitory effect of burdock leaves on elastase and tyrosinase activity. Exp Ther Med. 2017 Oct;14(4):3247-3252. doi: 10.3892/etm.2017.4880. Epub 2017 Aug 03. PMID: 28912875; PMCID: PMC5585880.
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Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography.

Arab journal of urology

Murray KM, Parker W, Stephany H, Redger K, Mirza M, Lopez-Corona E, Holzbeierlein JM, Lee EK.
PMID: 26966592
Arab J Urol. 2016 Mar;14(1):37-43. doi: 10.1016/j.aju.2015.11.002. Epub 2015 Dec 29.

OBJECTIVES: To detect the incidence of immediate postoperative deep vein thrombosis (DVT) using screening lower extremity ultrasonography (US) in patients undergoing radical cystectomy (RC) and to determine the rate of symptomatic pulmonary embolism (PE) after RC and identify risk...

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Murray KM, Parker W, Stephany H, et al. Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography. Arab J Urol. 2015;14(1):37-43doi: 10.1016/j.aju.2015.11.002.
Murray, K. M., Parker, W., Stephany, H., Redger, K., Mirza, M., Lopez-Corona, E., Holzbeierlein, J. M., & Lee, E. K. (2016). Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography. Arab journal of urology, 14(1), 37-43. https://doi.org/10.1016/j.aju.2015.11.002
Murray, Katie M, et al. "Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography." Arab journal of urology vol. 14,1 (2016): 37-43. doi: https://doi.org/10.1016/j.aju.2015.11.002
Murray KM, Parker W, Stephany H, Redger K, Mirza M, Lopez-Corona E, Holzbeierlein JM, Lee EK. Venous thromboembolism after radical cystectomy: Experience with screening ultrasonography. Arab J Urol. 2016 Mar;14(1):37-43. doi: 10.1016/j.aju.2015.11.002. Epub 2015 Dec 29. PMID: 26966592; PMCID: PMC4767786.
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Inhibition of lung cancer growth by HangAmDan-B is mediated by macrophage activation to M1 subtype.

Oncology letters

Park HR, Lee EJ, Moon SC, Chung TW, Kim KJ, Yoo HS, Cho CK, Ha KT.
PMID: 28454399
Oncol Lett. 2017 Apr;13(4):2330-2336. doi: 10.3892/ol.2017.5730. Epub 2017 Feb 13.

Re-education of tumor-associated macrophages (TAMs) toward antitumor effectors may be a promising therapeutic strategy for the successful treatment of cancer. HangAmDan-B (HAD-B), a herbal formula, has been used for stimulating immune function and activation of vital energy to cancer...

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Park HR, Lee EJ, Moon SC, et al. Inhibition of lung cancer growth by HangAmDan-B is mediated by macrophage activation to M1 subtype. Oncol Lett. 2017;13(4):2330-2336doi: 10.3892/ol.2017.5730.
Park, H. R., Lee, E. J., Moon, S. C., Chung, T. W., Kim, K. J., Yoo, H. S., Cho, C. K., & Ha, K. T. (2017). Inhibition of lung cancer growth by HangAmDan-B is mediated by macrophage activation to M1 subtype. Oncology letters, 13(4), 2330-2336. https://doi.org/10.3892/ol.2017.5730
Park, Hye-Rin, et al. "Inhibition of lung cancer growth by HangAmDan-B is mediated by macrophage activation to M1 subtype." Oncology letters vol. 13,4 (2017): 2330-2336. doi: https://doi.org/10.3892/ol.2017.5730
Park HR, Lee EJ, Moon SC, Chung TW, Kim KJ, Yoo HS, Cho CK, Ha KT. Inhibition of lung cancer growth by HangAmDan-B is mediated by macrophage activation to M1 subtype. Oncol Lett. 2017 Apr;13(4):2330-2336. doi: 10.3892/ol.2017.5730. Epub 2017 Feb 13. PMID: 28454399; PMCID: PMC5403442.
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Prediction of lymph node metastasis in patients with apparent early endometrial cancer.

Obstetrics & gynecology science

Son JH, Kong TW, Kim SH, Paek J, Chang SJ, Lee EJ, Ryu HS.
PMID: 26430663
Obstet Gynecol Sci. 2015 Sep;58(5):385-90. doi: 10.5468/ogs.2015.58.5.385. Epub 2015 Sep 22.

OBJECTIVE: The purpose of this study is to investigate the incidence of lymph node metastasis in early endometrial cancer patients and to evaluate preoperative clinicopathological factors predicting lymph node metastasis.METHODS: We identified 142 patients with endometrial cancer between January...

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Son JH, Kong TW, Kim SH, et al. Prediction of lymph node metastasis in patients with apparent early endometrial cancer. Obstet Gynecol Sci. 2015;58(5):385-90doi: 10.5468/ogs.2015.58.5.385.
Son, J. H., Kong, T. W., Kim, S. H., Paek, J., Chang, S. J., Lee, E. J., & Ryu, H. S. (2015). Prediction of lymph node metastasis in patients with apparent early endometrial cancer. Obstetrics & gynecology science, 58(5), 385-90. https://doi.org/10.5468/ogs.2015.58.5.385
Son, Joo-Hyuk, et al. "Prediction of lymph node metastasis in patients with apparent early endometrial cancer." Obstetrics & gynecology science vol. 58,5 (2015): 385-90. doi: https://doi.org/10.5468/ogs.2015.58.5.385
Son JH, Kong TW, Kim SH, Paek J, Chang SJ, Lee EJ, Ryu HS. Prediction of lymph node metastasis in patients with apparent early endometrial cancer. Obstet Gynecol Sci. 2015 Sep;58(5):385-90. doi: 10.5468/ogs.2015.58.5.385. Epub 2015 Sep 22. PMID: 26430663; PMCID: PMC4588843.
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Characterization of EST Gene in the Bovine Corpus Luteum during the Estrous Cycle.

Development & reproduction

Lee E, Kim SH, Kim BG, Yoon JT.
PMID: 26973974
Dev Reprod. 2015 Dec;19(4):227-34. doi: 10.12717/DR.2015.19.4.227.

The objective of this study was to investigate the expression of bovine luteum expressed sequence tags (ESTs), vascular endothelial growth factor (VEGF), and tumor necrosis factor receptor 1 (TNFR1) and the presence of functional ESTs in the bovine corpus...

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Lee E, Kim SH, Kim BG, et al. Characterization of EST Gene in the Bovine Corpus Luteum during the Estrous Cycle. Dev Reprod. 2015;19(4):227-34doi: 10.12717/DR.2015.19.4.227.
Lee, E., Kim, S. H., Kim, B. G., & Yoon, J. T. (2015). Characterization of EST Gene in the Bovine Corpus Luteum during the Estrous Cycle. Development & reproduction, 19(4), 227-34. https://doi.org/10.12717/DR.2015.19.4.227
Lee, Eunyoung, et al. "Characterization of EST Gene in the Bovine Corpus Luteum during the Estrous Cycle." Development & reproduction vol. 19,4 (2015): 227-34. doi: https://doi.org/10.12717/DR.2015.19.4.227
Lee E, Kim SH, Kim BG, Yoon JT. Characterization of EST Gene in the Bovine Corpus Luteum during the Estrous Cycle. Dev Reprod. 2015 Dec;19(4):227-34. doi: 10.12717/DR.2015.19.4.227. PMID: 26973974; PMCID: PMC4786484.
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Transcription Factors Regulating Inflammatory Cytokine Production Are Differentially Expressed in Peripheral Blood Mononuclear Cells of Behçet Disease Depending on Disease Activity.

Annals of dermatology

Woo MY, Yun SJ, Lee MJ, Kim K, Lee ES, Park S.
PMID: 28392644
Ann Dermatol. 2017 Apr;29(2):173-179. doi: 10.5021/ad.2017.29.2.173. Epub 2017 Mar 24.

BACKGROUND: Behçet disease (BD) is a relapsing inflammatory disease with increased production of inflammatory cytokines in peripheral blood mononuclear cells (PBMCs); however, the underlying molecular mechanisms are not well known.OBJECTIVE: To analyze whether the differential expression of transcription factors...

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Woo MY, Yun SJ, Lee MJ, et al. Transcription Factors Regulating Inflammatory Cytokine Production Are Differentially Expressed in Peripheral Blood Mononuclear Cells of Behçet Disease Depending on Disease Activity. Ann Dermatol. 2017;29(2):173-179doi: 10.5021/ad.2017.29.2.173.
Woo, M. Y., Yun, S. J., Lee, M. J., Kim, K., Lee, E. S., & Park, S. (2017). Transcription Factors Regulating Inflammatory Cytokine Production Are Differentially Expressed in Peripheral Blood Mononuclear Cells of Behçet Disease Depending on Disease Activity. Annals of dermatology, 29(2), 173-179. https://doi.org/10.5021/ad.2017.29.2.173
Woo, Min-Yeong, et al. "Transcription Factors Regulating Inflammatory Cytokine Production Are Differentially Expressed in Peripheral Blood Mononuclear Cells of Behçet Disease Depending on Disease Activity." Annals of dermatology vol. 29,2 (2017): 173-179. doi: https://doi.org/10.5021/ad.2017.29.2.173
Woo MY, Yun SJ, Lee MJ, Kim K, Lee ES, Park S. Transcription Factors Regulating Inflammatory Cytokine Production Are Differentially Expressed in Peripheral Blood Mononuclear Cells of Behçet Disease Depending on Disease Activity. Ann Dermatol. 2017 Apr;29(2):173-179. doi: 10.5021/ad.2017.29.2.173. Epub 2017 Mar 24. PMID: 28392644; PMCID: PMC5383742.
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Showing 13 to 24 of 3892 entries