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Showing 1 to 12 of 2510 entries
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Noise-aided logic in an electronic analog of synthetic genetic networks.

PloS one

Hellen EH, Dana SK, Kurths J, Kehler E, Sinha S.
PMID: 24124531
PLoS One. 2013 Oct 04;8(10):e76032. doi: 10.1371/journal.pone.0076032. eCollection 2013.

We report the experimental verification of noise-enhanced logic behaviour in an electronic analog of a synthetic genetic network, composed of two repressors and two constitutive promoters. We observe good agreement between circuit measurements and numerical prediction, with the circuit...

Detecting and Characterizing Pleiotropy: New Methods for Uncovering the Connection Between the Complexity of Genomic Architecture and Multiple phenotypes.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing

Tyler AL, Crawford DC, Pendergrass SA.
PMID: 25072629
Pac Symp Biocomput. 2014 Jan;183-187. doi: 10.1142/9789814583220_0018.

No abstract available.

Synthesis and SAR of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones as Inhibitors of D-Amino Acid Oxidase.

ACS medicinal chemistry letters

Berry JF, Ferraris DV, Duvall B, Hin N, Rais R, Alt J, Thomas AG, Rojas C, Hashimoto K, Slusher BS, Tsukamoto T.
PMID: 23243487
ACS Med Chem Lett. 2012 Oct 11;3(10):839-843. doi: 10.1021/ml300212a. Epub 2012 Sep 16.

A series of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones were synthesized and evaluated for their ability to inhibit human and porcine forms of D-amino acid oxidase (DAAO). Inhibitory potency is largely dependent on the size and position of substituents on the benzene ring with...

Effect of DAPT, a gamma secretase inhibitor, on tumor angiogenesis in control mice.

Advanced biomedical research

Kalantari E, Saeidi H, Kia NS, Tahergorabi Z, Rashidi B, Dana N, Khazaei M.
PMID: 24520550
Adv Biomed Res. 2013 Nov 30;2:83. doi: 10.4103/2277-9175.122498. eCollection 2013.

BACKGROUND: Notch signaling is a key factor for angiogenesis in physiological and pathological condition and γ-secretase is the regulator of Notch signaling. The main goal of this study was to assess the effect of (N-[N-(3,5-Diflurophenaacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester) DAPT, a...

Bilateral corneal ulceration in ocular graft-versus-host disease.

Clinical ophthalmology (Auckland, N.Z.)

Stevenson W, Shikari H, Saboo US, Amparo F, Dana R.
PMID: 24204119
Clin Ophthalmol. 2013;7:2153-8. doi: 10.2147/OPTH.S51180. Epub 2013 Oct 31.

PURPOSE: To report on corneal ulceration in ocular graft-versus-host disease (GVHD).METHODS: This was a retrospective, observational case series investigating corneal ulceration and perforation in a cohort of ocular GVHD patients seen between June 2007 and October 2012.RESULTS: Four of...

The Consortium for Electrocardiographic Imaging.

Computing in cardiology

Coll-Font J, Dhamala J, Potyagaylo D, Schulze WH, Tate JD, Guillem MS, van Dam P, Dossel O, Brooks DH, Macleod RS.
PMID: 28451592
Comput Cardiol (2010). 2016 Sep;43:325-328. Epub 2017 Mar 02.

Electrocardiographic imaging (ECGI) has recently gained attention as a viable diagnostic tool for reconstructing cardiac electrical activity in normal hearts as well as in cardiac arrhythmias. However, progress has been limited by the lack of both standards and unbiased...

Laser waveform control of extreme ultraviolet high harmonics from solids.

Optics letters

You YS, Wu M, Yin Y, Chew A, Ren X, Gholam-Mirzaei S, Browne DA, Chini M, Chang Z, Schafer KJ, Gaarde MB, Ghimire S.
PMID: 28454168
Opt Lett. 2017 May 01;42(9):1816-1819. doi: 10.1364/OL.42.001816.

Solid-state high-harmonic sources offer the possibility of compact, high-repetition-rate attosecond light emitters. However, the time structure of high harmonics must be characterized at the sub-cycle level. We use strong two-cycle laser pulses to directly control the time-dependent nonlinear current...

Popcorn ball calcification.

Abdominal radiology (New York)

Amiraian DE, DiSantis DJ.
PMID: 27639562
Abdom Radiol (NY). 2016 Dec;41(12):2330-2331. doi: 10.1007/s00261-016-0902-9.

No abstract available.

Testosterone inhibits expression of lipogenic genes in visceral fat by an estrogen-dependent mechanism.

Journal of applied physiology (Bethesda, Md. : 1985)

Holland AM, Roberts MD, Mumford PW, Mobley CB, Kephart WC, Conover CF, Beggs LA, Balaez A, Otzel DM, Yarrow JF, Borst SE, Beck DT.
PMID: 27539493
J Appl Physiol (1985). 2016 Sep 01;121(3):792-805. doi: 10.1152/japplphysiol.00238.2016. Epub 2016 Aug 18.

The influence of the aromatase enzyme on the chronic fat-sparing effects of testosterone requires further elucidation. Our purpose was to determine whether chronic anastrozole (AN, an aromatase inhibitor) treatment alters testosterone-mediated lipolytic/lipogenic gene expression in visceral fat. Ten-month-old Fischer...

Evaluating the reliability of the Attitudes to Randomized Trial Questionnaire (ARTQ) in a predominantly African American sample.

SpringerPlus

Ford ME, Wei W, Moore LA, Burshell DR, Cannady K, Mack F, Ezerioha N, Ercole K, Garrett-Mayer E.
PMID: 26266082
Springerplus. 2015 Aug 12;4:411. doi: 10.1186/s40064-015-1208-z. eCollection 2015.

PURPOSE: To evaluate the reliability of the Attitudes to Randomized Trial Questionnaire (ARTQ) in measuring perceptions of cancer clinical trials in a predominantly African American (AA) sample in South Carolina (SC).METHODS: Principal Component Analysis (PCA) and Cronbach's alpha estimates...

Molecular Design for Tuning Work Functions of Transparent Conducting Electrodes.

The journal of physical chemistry letters

Koldemir U, Braid JL, Morgenstern A, Eberhart M, Collins RT, Olson DC, Sellinger A.
PMID: 26266603
J Phys Chem Lett. 2015 Jun 18;6(12):2269-76. doi: 10.1021/acs.jpclett.5b00420. Epub 2015 Jun 04.

In this Perspective, we provide a brief background on the use of aromatic phosphonic acid modifiers for tuning work functions of transparent conducting oxides, for example, zinc oxide (ZnO) and indium tin oxide (ITO). We then introduce our preliminary...

Transforming Ward Rounds Through Rounding-in-Flow.

Journal of graduate medical education

Calderon AS, Blackmore CC, Williams BL, Chawla KP, Nelson-Peterson DL, Ingraham MD, Smith DL, Kaplan GS.
PMID: 26140131
J Grad Med Educ. 2014 Dec;6(4):750-5. doi: 10.4300/JGME-D-13-00324.1.

BACKGROUND: Traditional "batched" bedside clinical care rounds, where rounds for all patients precede clinical tasks, may delay clinical care and reduce resident work efficiency.INNOVATION: Using Lean concepts, we developed a novel "Rounding-in-Flow" approach, with the patient care team completing...

Showing 1 to 12 of 2510 entries