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Showing 1 to 12 of 20 entries
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Women entrepreneurship in STEM fields: literature review and future research avenues

STEM and gender

De L, Foss L, Mari M, Poggesi S.
GSID: lK3ndlf32HsJ
S Poggesi, M Mari, L De Vita, L Foss - International Entrepreneurship and …, 2020 - Springer

… that STEM fields are generally characterized by a strong gender … This gender gap in STEM education is typically ascribed to … gender stereotypes, based on the idea of specific gender …

Benefits of Combined All-Trans Retinoic Acid and Arsenic Trioxide Treatment of Acute Promyelocytic Leukemia Cells and Further Enhancement by Inhibition of Atypically Expressed Transglutaminase 2.

Cancers

Jambrovics K, Uray IP, Keillor JW, Fésüs L, Balajthy Z.
PMID: 32168763
Cancers (Basel). 2020 Mar 11;12(3). doi: 10.3390/cancers12030648.

Randomized trials in acute promyelocytic leukemia patients have shown that treatment with a combination of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) is superior in efficacy to monotherapy, with significantly decreased mortality. So far, there are little data...

Evolution of the Gram-Negative Antibiotic Resistance Spiral over Time: A Time-Series Analysis.

Antibiotics (Basel, Switzerland)

Tóth H, Buchholcz G, Fésüs A, Balázs B, Nagy JB, Majoros L, Szarka K, Kardos G.
PMID: 34204497
Antibiotics (Basel). 2021 Jun 17;10(6). doi: 10.3390/antibiotics10060734.

We followed up the interplay between antibiotic use and resistance over time in a tertiary-care hospital in Hungary. Dynamic relationships between monthly time-series of antibiotic consumption data (defined daily doses per 100 bed-days) and of incidence densities of Gram-negative...

The Effect of Pharmacist-Led Intervention on Surgical Antibacterial Prophylaxis (SAP) at an Orthopedic Unit.

Antibiotics (Basel, Switzerland)

Fésüs A, Benkő R, Matuz M, Kungler-Gorácz O, Fésüs MÁ, Bazsó T, Csernátony Z, Kardos G.
PMID: 34943721
Antibiotics (Basel). 2021 Dec 09;10(12). doi: 10.3390/antibiotics10121509.

Perioperative antibiotic use is a common reason for antibiotic misuse. Evidence suggests that adherence to SAP guidelines may improve outcomes. The purpose of this study was to analyze the impact of pharmacist-led antibiotic stewardship interventions on SAP guideline compliance....

Gamma-gliadin specific celiac disease antibodies recognize p31-43 and p57-68 alpha gliadin peptides in deamidation related manner as a result of cross-reaction.

Amino acids

Diós Á, Elek R, Szabó I, Horváth S, Gyimesi J, Király R, Werkstetter K, Koletzko S, Fésüs L, Korponay-Szabó IR.
PMID: 34059947
Amino Acids. 2021 Jul;53(7):1051-1063. doi: 10.1007/s00726-021-03006-7. Epub 2021 May 31.

Celiac disease (CeD) is a T-cell-dependent enteropathy with autoimmune features where tissue transglutaminase (TG2)-mediated posttranslational modification of gliadin peptides has a decisive role in the pathomechanism. The humoral immune response is reported to target mainly TG2-deamidated γ-gliadin peptides. However,...

The Effect of Pharmacist-Led Intervention on Surgical Antibacterial Prophylaxis (SAP) at an Orthopedic Unit.

Antibiotics (Basel, Switzerland)

Fésüs A, Benkő R, Matuz M, Kungler-Gorácz O, Fésüs MÁ, Bazsó T, Csernátony Z, Kardos G.
PMID: 34943721
Antibiotics (Basel). 2021 Dec 09;10(12). doi: 10.3390/antibiotics10121509.

Perioperative antibiotic use is a common reason for antibiotic misuse. Evidence suggests that adherence to SAP guidelines may improve outcomes. The purpose of this study was to analyze the impact of pharmacist-led antibiotic stewardship interventions on SAP guideline compliance....

Efficiency of long-term high-dose intravenous ascorbic acid therapy in locally advanced basal cell carcinoma - a pilot study.

Postepy dermatologii i alergologii

Bánvölgyi A, Lőrincz K, Kiss N, Avci P, Fésűs L, Szipőcs R, Krenács T, Gyöngyösi N, Wikonkál N, Kárpáti S, Németh K.
PMID: 32994778
Postepy Dermatol Alergol. 2020 Aug;37(4):548-558. doi: 10.5114/ada.2019.83027. Epub 2019 Feb 26.

INTRODUCTION: The anti-cancer properties of high-dose intravenous ascorbic acid have been demonstrated in various malignancies. In our recent study, we tested topically applied ascorbic acid to treat basal cell carcinoma (BCC), and achieved a good clinical response.AIM: Based on...

Author Correction: A nonlinear time-series analysis approach to identify thresholds in associations between population antibiotic use and rates of resistance.

Nature microbiology

López-Lozano JM, Lawes T, Nebot C, Beyaert A, Bertrand X, Hocquet D, Aldeyab M, Scott M, Conlon-Bingham G, Farren D, Kardos G, Fésűs A, Rodríguez-Baño J, Retamar P, Gonzalo-Jiménez N, Gould IM.
PMID: 32958859
Nat Microbiol. 2020 Nov;5(11):1449. doi: 10.1038/s41564-020-00796-6.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Quantitative Multispectral Imaging Differentiates Melanoma from Seborrheic Keratosis.

Diagnostics (Basel, Switzerland)

Bozsányi S, Farkas K, Bánvölgyi A, Lőrincz K, Fésűs L, Anker P, Zakariás S, Jobbágy A, Lihacova I, Lihachev A, Lange M, Bliznuks D, Medvecz M, Kiss N, Wikonkál NM.
PMID: 34441250
Diagnostics (Basel). 2021 Jul 22;11(8). doi: 10.3390/diagnostics11081315.

Melanoma is a melanocytic tumor that is responsible for the most skin cancer-related deaths. By contrast, seborrheic keratosis (SK) is a very common benign lesion with a clinical picture that may resemble melanoma. We used a multispectral imaging device...

Role of Tissue Transglutaminase Catalytic and Guanosine Triphosphate-Binding Domains in Renal Cell Carcinoma Progression.

ACS omega

Ulukan B, Bihorac A, Sipahioglu T, Kiraly R, Fesus L, Telci D.
PMID: 33163811
ACS Omega. 2020 Oct 20;5(43):28273-28284. doi: 10.1021/acsomega.0c04226. eCollection 2020 Nov 03.

Tissue transglutaminase (TG2) is a multifunctional protein that can act as a cross-linking enzyme, GTPase/ATPase, protein kinase, and protein disulfide isomerase. TG2 is involved in cell adhesion, migration, invasion, and growth, as well as epithelial-mesenchymal transition (EMT). Our previous...

FEBS Open Bio: past, present and future.

FEBS open bio

Wright DE, Goñi FM, Purton M, Fésüs L, Buchner J, Mowbray J, De la Rosa MA.
PMID: 34851554
FEBS Open Bio. 2021 Dec;11(12):3183-3188. doi: 10.1002/2211-5463.13326.

In celebration of the 10th anniversary of FEBS Open Bio, we spoke to some of the key figures of the journal's genesis, development, and its future direction, and recount here their thoughts and experiences. Prof. Félix. Goñi discusses the...

Biochemical Characterisation of Human Transglutaminase 4.

International journal of molecular sciences

Csobán-Szabó Z, Bécsi B, El Alaoui S, Fésüs L, Korponay-Szabó IR, Király R.
PMID: 34830327
Int J Mol Sci. 2021 Nov 18;22(22). doi: 10.3390/ijms222212448.

Transglutaminases are protein-modifying enzymes involved in physiological and pathological processes with potent therapeutic possibilities. Human TG4, also called prostate transglutaminase, is involved in the development of autoimmune and tumour diseases. Although rodent TG4 is well characterised, biochemical characteristics of...

Showing 1 to 12 of 20 entries